ES2129474T3 - Procedimiento de dosificado inmunologico por medio de espectros raman exaltados de superficie (sers). - Google Patents

Procedimiento de dosificado inmunologico por medio de espectros raman exaltados de superficie (sers).

Info

Publication number
ES2129474T3
ES2129474T3 ES93113836T ES93113836T ES2129474T3 ES 2129474 T3 ES2129474 T3 ES 2129474T3 ES 93113836 T ES93113836 T ES 93113836T ES 93113836 T ES93113836 T ES 93113836T ES 2129474 T3 ES2129474 T3 ES 2129474T3
Authority
ES
Spain
Prior art keywords
analyte
raman
test mixture
exalted
sers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93113836T
Other languages
English (en)
Inventor
Peter J Tarcha
Thomas E Rohr
James J Markese
Therese Cotton
Bernard Rospendowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2129474T3 publication Critical patent/ES2129474T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/801—Electron dense compounds, e.g. ferritin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Abstract

SE DESCRIBEN UN METODO, COMPOSICION, DISPOSITIVO, APARATO, Y EQUIPO PARA LA DETERMINACION DE LA PRESENCIA DE UNA CANTIDAD DE UNA ANALITA AL VISUALIZAR UN SUCESO DE ENLACE MEDIADO POR ANALITA EN UNA MEZCLA DE PRUEBA QUE CONTIENE LA ANALITA A ANALIZAR, UN MIEMBRO DE ENLACE ESPECIFICO, UNA ETIQUETA RAMAN-ACTIVA CON UNA SUPERFICIE CAPAZ DE INDUCIR LA DIFUSION DE LUZ RAMAN DE SUPERFICIE INTENSIFICADA. LA MEZCLA DE ENSAYO SE ILUMINA CON UNA RADIACION SUFICIENTE PARA CAUSAR LA ETIQUETA RAMAN ACTIVA PARA EMITIR UN ESPECTRO RAMAN DETECTABLE. LAS DIFERENCIAS EN LA DIFUSION RAMAN DE SUPERFICIE INTENSIFICADA DETECTADA SON DEPENDIENTES DE LA CANTIDAD DE ANALITA PRESENTE EN LA MEZCLA DE ENSAYO. ASI, AL VISUALIZAR LAS DIFERENCIAS, LA PRESENCIA DE UNA CANTIDAD DE ANALITA SE DETERMINA.
ES93113836T 1992-09-11 1993-08-30 Procedimiento de dosificado inmunologico por medio de espectros raman exaltados de superficie (sers). Expired - Lifetime ES2129474T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/944,138 US5376556A (en) 1989-10-27 1992-09-11 Surface-enhanced Raman spectroscopy immunoassay

Publications (1)

Publication Number Publication Date
ES2129474T3 true ES2129474T3 (es) 1999-06-16

Family

ID=25480865

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93113836T Expired - Lifetime ES2129474T3 (es) 1992-09-11 1993-08-30 Procedimiento de dosificado inmunologico por medio de espectros raman exaltados de superficie (sers).

Country Status (12)

Country Link
US (2) US5376556A (es)
EP (1) EP0587008B1 (es)
JP (1) JP3444630B2 (es)
KR (1) KR940007533A (es)
AT (1) ATE176727T1 (es)
AU (1) AU4625993A (es)
CA (1) CA2105782A1 (es)
DE (1) DE69323459T2 (es)
DK (1) DK0587008T3 (es)
ES (1) ES2129474T3 (es)
GR (1) GR3029912T3 (es)
TW (1) TW240291B (es)

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EP0587008A1 (en) 1994-03-16
US5567628A (en) 1996-10-22
CA2105782A1 (en) 1994-03-12
DE69323459D1 (de) 1999-03-25
AU4625993A (en) 1994-03-17
DK0587008T3 (da) 1999-09-20
JPH06174723A (ja) 1994-06-24
US5376556A (en) 1994-12-27
TW240291B (es) 1995-02-11
EP0587008B1 (en) 1999-02-10
GR3029912T3 (en) 1999-07-30
ATE176727T1 (de) 1999-02-15
DE69323459T2 (de) 1999-09-02
JP3444630B2 (ja) 2003-09-08
KR940007533A (ko) 1994-04-27

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