ES2125901T3 - Empleo de lipasas para la obtencion de medicamentos. - Google Patents
Empleo de lipasas para la obtencion de medicamentos.Info
- Publication number
- ES2125901T3 ES2125901T3 ES92912628T ES92912628T ES2125901T3 ES 2125901 T3 ES2125901 T3 ES 2125901T3 ES 92912628 T ES92912628 T ES 92912628T ES 92912628 T ES92912628 T ES 92912628T ES 2125901 T3 ES2125901 T3 ES 2125901T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- lipases
- sec
- date
- pub
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/38—Pseudomonas
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/21—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
- G01N2333/918—Carboxylic ester hydrolases (3.1.1)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nutrition Science (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
SE DESCRIBE LA APLICACION DE UNA LIPASA BACTERIAL QUE INDICA UNA REACCION CRUCIAL INMUNOLOGICA POSITIVA CON LOS ANTICUERPOS DE LIPASA, QUE SE FORMAN A PARTIR DE MICROORGANISMOS PSEUDOMONAS SPEC DSM 6843 Y/O PSEUDOMONAS CEPACIA IAM 1057, PARA PRODUCIR MEDICAMENTOS PARA LA TERAPIA DE TRASTORNOS DEL APARATO DIGESTIVO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4121704 | 1991-07-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2125901T3 true ES2125901T3 (es) | 1999-03-16 |
Family
ID=6435147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92912628T Expired - Lifetime ES2125901T3 (es) | 1991-07-01 | 1992-06-23 | Empleo de lipasas para la obtencion de medicamentos. |
Country Status (10)
Country | Link |
---|---|
US (3) | US5489530A (es) |
EP (1) | EP0592478B1 (es) |
JP (1) | JP3593550B2 (es) |
AT (1) | ATE175117T1 (es) |
CA (1) | CA2110497C (es) |
DE (1) | DE59209604D1 (es) |
DK (1) | DK0592478T3 (es) |
ES (1) | ES2125901T3 (es) |
MX (1) | MX9203832A (es) |
WO (1) | WO1993000924A1 (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6140475A (en) * | 1997-04-11 | 2000-10-31 | Altus Biologics Inc. | Controlled dissolution crosslinked protein crystals |
US20010046493A1 (en) * | 2000-02-24 | 2001-11-29 | Alex Margolin | Lipase-containing composition and methods of use thereof |
DE10032058A1 (de) * | 2000-07-05 | 2002-01-17 | Basf Ag | Mikrobielle Produktion von R-Phenylacetylcarbinol durch biologische Umwandlung von Benzaldehyd durch filamentöse Pilze |
US20040033220A1 (en) * | 2000-11-02 | 2004-02-19 | Marcus Hartmann | Use of enzymes obtained from ciliates as medicaments for promoting digestion |
AU785249B2 (en) * | 2002-04-24 | 2006-12-07 | Asahi Industrial Co., Ltd. | New microorganism and drainage method |
US7172895B2 (en) * | 2002-04-25 | 2007-02-06 | Takuya Kitamura | Microorganism and drainage method |
US7142464B2 (en) * | 2003-04-29 | 2006-11-28 | Saifun Semiconductors Ltd. | Apparatus and methods for multi-level sensing in a memory array |
JP5032300B2 (ja) * | 2004-03-22 | 2012-09-26 | アボット プロダクツ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 界面活性剤を含有している、リパーゼを含有する生成物の、とりわけパンクレアチンの経口医薬組成物 |
UA91521C2 (ru) * | 2004-10-14 | 2010-08-10 | Элтус Фармасьютикалз Инк. | Композиции, содержащие липазу, протеазу и амилазу, предназначенные для лечения недостаточности поджелудочной железы |
CA2616943C (en) * | 2005-07-29 | 2016-04-12 | Solvay Pharmaceuticals Gmbh | Processes for the manufacture of sterilized pancreatin powder |
US9198871B2 (en) | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
US11266607B2 (en) | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
US20100196344A1 (en) * | 2005-10-14 | 2010-08-05 | Cystic Fibrosis Foundation Therapeutics, Inc. | Compositions and methods for treating pancreatic insufficiency |
WO2007053619A2 (en) * | 2005-11-01 | 2007-05-10 | Bio-Cat, Inc. | A composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrous as well as people suffering from pancreatic lipase insufficiency |
US10072256B2 (en) | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
US20090130063A1 (en) * | 2007-11-15 | 2009-05-21 | Solvay Pharmaceuticals Gmbh | Process for separating and determining the viral load in a pancreatin sample |
CN106139132A (zh) * | 2009-01-29 | 2016-11-23 | 诺尔玛克药物有限责任及股份两合公司 | 细菌脂肪酶药物制剂 |
DE102009006594A1 (de) | 2009-01-29 | 2010-08-05 | Nordmark Arzneimittel Gmbh & Co. Kg | Pharmazeutisches Präparat |
PL2391382T3 (pl) | 2009-01-29 | 2014-11-28 | Nordmark Arzneimittel Gmbh & Co Kg | Preparat farmaceutyczny zawierający lipazę pochodzenia bakteryjnego |
JP2014193909A (ja) * | 2014-06-04 | 2014-10-09 | Nordmark Arzneimittel Gmbh & Co Kg | 医薬調製物 |
WO2016126970A1 (en) | 2015-02-04 | 2016-08-11 | Abbvie Inc. | Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency |
DE102015114857A1 (de) | 2015-09-04 | 2017-03-09 | Nordmark Arzneimittel Gmbh & Co. Kg | Getränk, enthaltend eine pharmazeutische Zusammensetzung |
DE102015114862A1 (de) | 2015-09-04 | 2017-03-09 | Nordmark Arzneimittel Gmbh & Co. Kg | Pharmazeutische Zusammensetzung, enthaltend eine bakterielle Lipase |
DE102015114859A1 (de) | 2015-09-04 | 2017-03-09 | Nordmark Arzneimittel Gmbh & Co. Kg | Verwendung einer pharmazeutischen Zusammensetzung, enthaltend mindestens ein Verdauungsenzym, bei der künstlichen Ernährung |
AU2017221289A1 (en) | 2016-02-19 | 2018-08-30 | Basf Se | Baking lipases |
DE102017104480A1 (de) | 2017-03-03 | 2018-09-06 | Nordmark Arzneimittel Gmbh & Co. Kg | Wässrige Lösung von Burlulipase umfassend Kalziumionen |
DE102017104472A1 (de) | 2017-03-03 | 2018-09-06 | Nordmark Arzneimittel Gmbh & Co. Kg | Schmelztablette enthaltend Burlulipase und daraus hergestellte pharmazeutische Zusammensetzung |
WO2018209018A1 (en) | 2017-05-12 | 2018-11-15 | Basf Se | Lipase enzymes |
CA3076578A1 (en) | 2017-10-25 | 2019-05-02 | Basf Se | Beta-amylase enzymes |
WO2020185737A1 (en) | 2019-03-11 | 2020-09-17 | Basf Se | Amylases and methods for making and using them |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1084431A (en) * | 1964-05-06 | 1967-09-20 | Analyses Et De Rech S Biolog M | Improvements in and relating to lipases |
US3431175A (en) * | 1964-07-18 | 1969-03-04 | Amano Pharma Co Ltd | Method for the preparation of a lipoprotein lipase by cultivating organisms |
DE1300487B (de) * | 1965-08-19 | 1969-08-07 | Hoechst Ag | Verfahren zur mikrobiologischen Herstellung von Lipase |
DE1642654C3 (de) * | 1968-01-16 | 1979-11-29 | Centre Europeen De Recherches Mauvernay, C.E.R.M., Riom | Verfahren zur mikrobiologischen Herstellung eines stabilen gereinigten Lipase-Präparates und pharmazeutisches Mittel, welches dieses enthält |
JPS4629787B1 (es) * | 1968-07-02 | 1971-08-30 | ||
US3875007A (en) * | 1972-11-03 | 1975-04-01 | Amano Pharma Co Ltd | Lipid metabolism improving and anti-atheromatic agent |
US4019959A (en) * | 1975-10-06 | 1977-04-26 | Continental Oil Company | Bacterial production of lipase and pyocyanine from n-paraffins |
US4283494A (en) * | 1978-04-26 | 1981-08-11 | Meito Sangyo Kabushiki Kaisha | Microbial lipase, process for its preparation and microbiologically pure culture therefor |
GB8514708D0 (en) * | 1985-06-11 | 1985-07-10 | Unilever Plc | Enzymatic detergent composition |
EP0318775B1 (en) * | 1987-12-03 | 1994-02-02 | Chisso Corporation | A lipase gene |
JP3079276B2 (ja) * | 1988-02-28 | 2000-08-21 | 天野製薬株式会社 | 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法 |
ES2059986T3 (es) * | 1989-03-08 | 1994-11-16 | Simon Lodewijk Scharpe | Una composicion para el tratamiento de la insuficiencia exocrina del pancreas, y el uso de dicha composicion. |
-
1992
- 1992-06-23 EP EP92912628A patent/EP0592478B1/de not_active Expired - Lifetime
- 1992-06-23 DE DE59209604T patent/DE59209604D1/de not_active Expired - Lifetime
- 1992-06-23 ES ES92912628T patent/ES2125901T3/es not_active Expired - Lifetime
- 1992-06-23 JP JP50191593A patent/JP3593550B2/ja not_active Expired - Lifetime
- 1992-06-23 AT AT92912628T patent/ATE175117T1/de not_active IP Right Cessation
- 1992-06-23 US US08/170,358 patent/US5489530A/en not_active Expired - Lifetime
- 1992-06-23 CA CA002110497A patent/CA2110497C/en not_active Expired - Lifetime
- 1992-06-23 WO PCT/EP1992/001412 patent/WO1993000924A1/de active IP Right Grant
- 1992-06-23 DK DK92912628T patent/DK0592478T3/da active
- 1992-06-30 MX MX9203832A patent/MX9203832A/es not_active IP Right Cessation
-
1995
- 1995-04-17 US US08/422,921 patent/US5645832A/en not_active Expired - Lifetime
-
1997
- 1997-03-20 US US08/821,729 patent/US6030798A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0592478B1 (de) | 1998-12-30 |
EP0592478A1 (de) | 1994-04-20 |
US6030798A (en) | 2000-02-29 |
DE59209604D1 (de) | 1999-02-11 |
ATE175117T1 (de) | 1999-01-15 |
JPH06509330A (ja) | 1994-10-20 |
US5645832A (en) | 1997-07-08 |
JP3593550B2 (ja) | 2004-11-24 |
MX9203832A (es) | 1993-01-01 |
US5489530A (en) | 1996-02-06 |
CA2110497A1 (en) | 1993-01-21 |
WO1993000924A1 (de) | 1993-01-21 |
DK0592478T3 (da) | 1999-08-30 |
CA2110497C (en) | 2005-04-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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