ES8707114A1 - Procedimiento para la obtencion de un anticuerpo monoclonal anti-alfa-amilasa - Google Patents

Procedimiento para la obtencion de un anticuerpo monoclonal anti-alfa-amilasa

Info

Publication number
ES8707114A1
ES8707114A1 ES552781A ES552781A ES8707114A1 ES 8707114 A1 ES8707114 A1 ES 8707114A1 ES 552781 A ES552781 A ES 552781A ES 552781 A ES552781 A ES 552781A ES 8707114 A1 ES8707114 A1 ES 8707114A1
Authority
ES
Spain
Prior art keywords
inhibition
monoclonal antibodies
human saliva
amylase
pancreas amylase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES552781A
Other languages
English (en)
Other versions
ES552781A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES8707114A1 publication Critical patent/ES8707114A1/es
Publication of ES552781A0 publication Critical patent/ES552781A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G3/00—Glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7154—Barrels, drums, tuns, vats

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

METODO DE OBTENER UN ANTICUERPO MONOCLONAL ANTI-ALFA-AMILASA. COMPRENDE: A) INMUNIZAR RATONES CON A-AMILASA, EN HIDROXIDO DE ALUMINIO Y CON PRESENCIA DE BORDETELLA PERTUSSIS; B) FUSIONAR A LOS RATONES DE LA ETAPA (A) CON CELULAS DE MIELOMA B-LINFOCITOS PROCEDENTRES DEL BAZO; C) CLONAR LAS CELULAS DE HIBRIDOMA FORMADAS; D) AISLAR LAS CELULAS CLONADAS; Y E) CULTIVAR LOS CLONES QUE INHIBEN LA A-AMILASA DE SALIVA Y LA AMILASA DE PANCREAS, PARA OBTENER ANTICUERPOS MONOCLONALES 77F5, NCACC 85022203 O 73CB. SE UTILIZAN COMO MEDICAMENTOS.
ES552781A 1985-03-08 1986-03-07 Procedimiento para la obtencion de un anticuerpo monoclonal anti-alfa-amilasa Expired ES8707114A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853508384 DE3508384A1 (de) 1985-03-08 1985-03-08 Hemmung humaner speichel- und pankreasamylase durch monoklonale antikoerper

Publications (2)

Publication Number Publication Date
ES8707114A1 true ES8707114A1 (es) 1987-08-01
ES552781A0 ES552781A0 (es) 1987-08-01

Family

ID=6264674

Family Applications (1)

Application Number Title Priority Date Filing Date
ES552781A Expired ES8707114A1 (es) 1985-03-08 1986-03-07 Procedimiento para la obtencion de un anticuerpo monoclonal anti-alfa-amilasa

Country Status (13)

Country Link
US (1) US4863728A (es)
EP (1) EP0194600A3 (es)
JP (1) JPS61218529A (es)
KR (1) KR860007275A (es)
AU (1) AU569816B2 (es)
DE (1) DE3508384A1 (es)
DK (1) DK105886A (es)
ES (1) ES8707114A1 (es)
HU (1) HUT40700A (es)
IE (1) IE860227L (es)
IL (1) IL77990A (es)
PT (1) PT82113B (es)
ZA (1) ZA861706B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3342736A1 (de) * 1983-11-25 1985-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Hybridoma-antikoerper
DE3621271A1 (de) * 1986-06-25 1988-01-07 Boehringer Mannheim Gmbh Verfahren und reagenz zur bestimmung von alpha-amylase
WO1988001386A1 (en) * 1986-08-13 1988-02-25 Humagen, Incorporated Production and diagnostic use of antibodies against pancreatic alpha-amylase
DK630886A (da) * 1986-10-17 1988-04-18 Kohjin Co Monoklonalt antistof mod human pancreas-amylase, fremgangsmaade til fremstilling deraf og fremgangsmaade til bestemmelse af human pancreas-amylase ved hjaelp af antistoffet
US5654163A (en) * 1991-04-23 1997-08-05 Boehringer Mannheim Gmbh Indophenol substituted maltooligosides as α-amylase substrates
AUPP705898A0 (en) * 1998-11-11 1998-12-03 Quality Wheat Crc Limited Detection of preharvest sprouting in cereal grains
US20080050451A1 (en) * 2006-06-16 2008-02-28 Mabry Helen C Methods for assessing dehydration and shock, assays and kits for the methods
WO2008013455A1 (en) * 2006-07-27 2008-01-31 Lactive B.V. Means and methods for preventing elevated blood glucose levels in humans with animal antibodies produced in milk
CA2787021A1 (en) * 2009-02-05 2010-08-12 Hydradx, Inc. Diagnostic device and method

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5296731A (en) * 1976-02-05 1977-08-13 Green Cross Corp:The Prophylactics and remedies of cyanomycosis
US4145527A (en) * 1976-07-13 1979-03-20 E. I. Du Pont De Nemours And Company Nitro aromatic glycosides
US4102747A (en) * 1977-07-28 1978-07-25 American Hospital Supply Corporation Amylase determination
AT362526B (de) * 1977-09-13 1981-05-25 Boehringer Mannheim Gmbh Verfahren und reagens zur bestimmung von alpha- -amylase
US4233403A (en) * 1978-02-27 1980-11-11 E. I. Du Pont De Nemours And Company Amylase assay
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
JPS58183098A (ja) * 1982-04-20 1983-10-26 Wako Pure Chem Ind Ltd アイソザイム分別定量法
EP0104047B1 (en) * 1982-09-16 1987-07-29 Wako Pure Chemical Industries, Ltd. Modified oligosaccharides used as substrate for measuring alpha-amylase activity
DE3342736A1 (de) * 1983-11-25 1985-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Hybridoma-antikoerper
FI844289L (fi) * 1984-01-21 1985-07-22 Hoechst Ag Nya polypeptider med -amylashaemmande verkan, foerfarande foer deras framstaellning, deras anvaendning och farmaceutiska preparat.
US4649108A (en) * 1984-07-26 1987-03-10 Genzyme Corporation Alpha amylase assay
JPS61194365A (ja) * 1985-02-23 1986-08-28 Wako Pure Chem Ind Ltd 単クロ−ン性抗α−アミラ−ゼ抗体及びこれを用いるα−アミラ−ゼの分別定量法

Also Published As

Publication number Publication date
IE860227L (en) 1986-09-08
DK105886A (da) 1986-09-09
IL77990A (en) 1990-02-09
DE3508384A1 (de) 1986-11-06
DK105886D0 (da) 1986-03-07
AU5265686A (en) 1986-09-18
ES552781A0 (es) 1987-08-01
ZA861706B (en) 1986-11-26
KR860007275A (ko) 1986-10-10
AU569816B2 (en) 1988-02-18
US4863728A (en) 1989-09-05
EP0194600A2 (de) 1986-09-17
PT82113B (pt) 1987-12-30
JPS61218529A (ja) 1986-09-29
HUT40700A (en) 1987-01-28
EP0194600A3 (de) 1988-03-16
PT82113A (de) 1986-03-01

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