ES2104626T3 - Secuencia de adn que comprende un gen codante para la reductasa de xilosa o la reductasa de xilosa y la deshidrogenasa de xilitol. - Google Patents

Secuencia de adn que comprende un gen codante para la reductasa de xilosa o la reductasa de xilosa y la deshidrogenasa de xilitol.

Info

Publication number
ES2104626T3
ES2104626T3 ES91104558T ES91104558T ES2104626T3 ES 2104626 T3 ES2104626 T3 ES 2104626T3 ES 91104558 T ES91104558 T ES 91104558T ES 91104558 T ES91104558 T ES 91104558T ES 2104626 T3 ES2104626 T3 ES 2104626T3
Authority
ES
Spain
Prior art keywords
xylose reductase
xylitol dehydrogenase
dna sequence
codating
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91104558T
Other languages
English (en)
Inventor
Alexander W M Dr Strasser
Cornelis P Prof Dr Hollenberg
Michael Von Pr Ciriacy-Wantrup
Peter Kotter
Rene Amore
Michael Piontek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dynavax GmbH
Original Assignee
Rhein Biotech GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhein Biotech GmbH filed Critical Rhein Biotech GmbH
Application granted granted Critical
Publication of ES2104626T3 publication Critical patent/ES2104626T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA INVENCION SE REFIERE A UNA SECUENCIA DE ADN QUE TIENE UN GEN ESTRUCTURAL QUE CODIFICA REDUCTASA DE XILOSA Y/O DEHIDROGENASA DE XILITOL Y QUE ES CAPAZ DE EXPRESAR ESTOS POLIPEPTIDOS EN UN MICROORGANISMO. LA INVENCION SE REFIERE ADEMAS A UNA COMBINACION DE SECUENCIAS DE ADN, UN VECTOR, UN MICROORGANISMO, UN METODO PARA PRODUCIR REDUCTASA DE XILOSA Y/O DEHIDROGENASA DE XILITOL. LOS MICROORGANISMOS, QUE EXPRESAN LOS GENES ESTRUCTURALES COMPRENDIDOS POR LAS SECUENCIAS DE ADN INVESTIVAS PUEDEN SER UTILIZADAS PARA PRODUCIR ETANOL A PARTIR DE XILULOSA, PARA PRODUCIR BIOMASA Y RECUPERAR NADP ELEVADO + DE NADPH. LOS MICROORGANISMOS PREFERIDOS SON S.CEREVISIAL Y SCHIZOSACCHAROMYCAS POMBE.
ES91104558T 1990-03-26 1991-03-22 Secuencia de adn que comprende un gen codante para la reductasa de xilosa o la reductasa de xilosa y la deshidrogenasa de xilitol. Expired - Lifetime ES2104626T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4009676A DE4009676A1 (de) 1990-03-26 1990-03-26 Dna-sequenz, umfassend ein fuer xylosereduktase und/oder xylitoldehydrogenase codierendes strukturgen

Publications (1)

Publication Number Publication Date
ES2104626T3 true ES2104626T3 (es) 1997-10-16

Family

ID=6403083

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91104558T Expired - Lifetime ES2104626T3 (es) 1990-03-26 1991-03-22 Secuencia de adn que comprende un gen codante para la reductasa de xilosa o la reductasa de xilosa y la deshidrogenasa de xilitol.

Country Status (8)

Country Link
EP (1) EP0450430B1 (es)
JP (3) JP3122153B2 (es)
AT (1) ATE154829T1 (es)
CA (1) CA2039021C (es)
DE (2) DE4009676A1 (es)
DK (1) DK0450430T3 (es)
ES (1) ES2104626T3 (es)
GR (1) GR3024409T3 (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5866382A (en) 1990-04-06 1999-02-02 Xyrofin Oy Xylose utilization by recombinant yeasts
FI901771A (fi) * 1990-04-06 1991-10-07 Valtion Teknillinen Anvaendning av xylos hos hybridjaest.
FI913197A0 (fi) * 1991-07-01 1991-07-01 Xyrofin Oy Nya jaeststammar med reducerad foermaoga att metabolisera xylitol, foerfarande foer bildande av dessa och deras anvaendning vid framstaellning av xylitol.
PL178040B1 (pl) * 1992-11-05 2000-02-29 Xyrofin Oy Sposób wytwarzania ksylitolu i zrekombinowany gospodarz drobnoustrojowy
EP0672161B1 (en) * 1992-11-05 1999-09-22 Xyrofin Oy Recombinant method and host for manufacture of xylitol
US7226761B2 (en) 1992-11-05 2007-06-05 Danisco Sweeteners Oy Manufacture of five-carbon sugars and sugar alcohols
US6723540B1 (en) 1992-11-05 2004-04-20 Xyrofin Oy Manufacture of xylitol using recombinant microbial hosts
JP3574682B2 (ja) * 1993-09-24 2004-10-06 ダイセル化学工業株式会社 新規な酵素、該酵素を製造する方法、該酵素をコードするｄｎａ、該ｄｎａを含む形質転換体、該酵素による光学活性アルコール等の製造方法
US5712114A (en) * 1995-06-06 1998-01-27 Basf Aktiengesellschaft Compositions for expression of proteins in host cells using a preprocollagen signal sequence
IN191596B (es) 1996-05-06 2003-12-06 Purdue Research Foundation
DE69928656D1 (de) * 1998-04-20 2006-01-05 Forskarpatent I Syd Ab Lund Gentechnisch hergestellte hefestämme und deren mutanten zur fermentierung von lignocellulosehydrolysate
JP2000295994A (ja) * 1999-02-09 2000-10-24 Ajinomoto Co Inc キシリトールの製造法
FI20010308A0 (fi) * 2001-02-16 2001-02-16 Valtion Teknillinen Sienen käsitteleminen geneettisesti siten, että se pystyy käyttämään L-arabinoosia
US7309602B2 (en) 2006-04-13 2007-12-18 Ambrozea, Inc. Compositions and methods for producing fermentation products and residuals
WO2007121100A2 (en) * 2006-04-13 2007-10-25 Ambrozea, Inc. Compositions and methods for producing fermentation products and residuals
PL2051824T3 (pl) * 2006-08-01 2020-11-16 Vwp Waste Processing Limited Recykling odpadów z gospodarstw domowych
BRPI0807237A2 (pt) 2007-02-02 2014-04-29 Kirin Holdings Kk Dna que codifica xilitol desidrogenase, construção de ácido nucléico, vetores, microorganismos e métodos para produzir xilitol desigrogenase e etanol
WO2008144012A2 (en) * 2007-05-14 2008-11-27 The Regents Of The University Of California Xylose- and arabinose- metabolizing enzyme -encoding nucleotide sequences with refined translational kinetics and methods of making same
WO2009064277A1 (en) 2007-11-16 2009-05-22 University Of Iowa Research Foundation Spray dried microbes and methods of preparation and use
JP5219074B2 (ja) * 2008-01-24 2013-06-26 独立行政法人産業技術総合研究所 キシロース発酵能が優れた六炭糖・五炭糖同時発酵酵母およびそれを用いたエタノールの高効率生産方法
CA2761877A1 (en) * 2009-02-23 2010-08-26 Kirin Holdings Kabushiki Kaisha Method for production of substance in candida utilis using xylose as carbon source
CA2779163A1 (en) 2009-12-30 2011-07-07 Iogen Energy Corporation Modified yeast strains exhibiting enhanced fermentation of lignocellulosic hydrolysates
WO2011099657A1 (ko) * 2010-02-10 2011-08-18 건국대학교 산학협력단 신규 자일리톨 탈수소화효소 및 이를 이용한 ｌ-자일룰로즈의 생산방법
WO2012024698A1 (en) 2010-08-20 2012-02-23 Codexis, Inc. Use of glycoside hydrolase 61 family proteins in processing of cellulose
JP5881300B2 (ja) * 2011-03-04 2016-03-09 サントリーホールディングス株式会社 リグノセルロース系バイオマスからのエタノール醗酵微生物
EP2748317B1 (en) 2011-08-22 2017-04-19 Codexis, Inc. Gh61 glycoside hydrolase protein variants and cofactors that enhance gh61 activity
US10202622B2 (en) 2014-07-22 2019-02-12 Iogen Corporation Process for producing fuel using two fermentations
US10619173B2 (en) 2014-07-22 2020-04-14 Iogen Corporation Process for using biogenic carbon dioxide derived from non-fossil organic material
US11434509B2 (en) 2014-12-08 2022-09-06 Iogen Corporation Process for using biogenic carbon dioxide derived from non-fossil organic material
US10513715B2 (en) 2015-09-24 2019-12-24 Iogen Corporation Wet oxidation of biomass
WO2017088061A1 (en) 2015-11-25 2017-06-01 Iogen Energy Corporation System and method for cooling pretreated biomass
CA3006672A1 (en) 2015-12-18 2017-06-22 Iogen Corporation Sulfur dioxide and/or sulfurous acid pretreatment
US10655149B2 (en) 2016-02-10 2020-05-19 Iogen Corporation Pretreatment of lignocellulosic biomass with sulfur dioxide and/or sulfurous acid
EP3559207A4 (en) * 2016-12-21 2020-08-12 Creatus Biosciences Inc. XYLITOL-PRODUCING METSCHNIKOWIA SPECIES
CA3078822A1 (en) 2017-11-09 2019-05-16 Iogen Corporation Low temperature sulfur dioxide pretreatment
US11345935B2 (en) 2017-11-09 2022-05-31 Iogen Corporation Low temperature pretreatment with sulfur dioxide
CA3094413A1 (en) 2018-04-06 2019-10-10 Iogen Corporation Pretreatment with lignosulfonic acid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2151635B (en) * 1983-12-08 1988-01-13 Ici Plc Production of single cell protein and sucrose
JPS60199383A (ja) * 1984-03-21 1985-10-08 Shigemi Morimoto ペンテイト−ル・デハイドロギナ−ゼとアルド−ズ・レダクタ−ゼの精製純化法
JPS6163291A (ja) * 1984-08-31 1986-04-01 Dai Ichi Kogyo Seiyaku Co Ltd 酵素法によるキシリト−ルの製造法
US4840903A (en) * 1985-08-08 1989-06-20 The United States Of America As Represented By The United States Department Of Energy Process for producing ethanol from plant biomass using the fungus paecilomyces sp.
DK122686D0 (da) * 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner

Also Published As

Publication number Publication date
DE4009676C2 (es) 1993-09-09
EP0450430B1 (en) 1997-06-25
JP2001103988A (ja) 2001-04-17
DE69126632T2 (de) 1997-10-23
CA2039021A1 (en) 1991-09-27
JP2000139486A (ja) 2000-05-23
JP3193917B2 (ja) 2001-07-30
JP3122153B2 (ja) 2001-01-09
EP0450430A2 (en) 1991-10-09
JPH06339383A (ja) 1994-12-13
CA2039021C (en) 2006-09-12
ATE154829T1 (de) 1997-07-15
DK0450430T3 (da) 1998-01-19
DE69126632D1 (de) 1997-07-31
EP0450430A3 (en) 1992-01-02
DE4009676A1 (de) 1991-10-02
GR3024409T3 (en) 1997-11-28

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