ES2101867T3 - Aplicaciones diagnosticas de la formacion de lazos d dobles. - Google Patents
Aplicaciones diagnosticas de la formacion de lazos d dobles.Info
- Publication number
- ES2101867T3 ES2101867T3 ES92918877T ES92918877T ES2101867T3 ES 2101867 T3 ES2101867 T3 ES 2101867T3 ES 92918877 T ES92918877 T ES 92918877T ES 92918877 T ES92918877 T ES 92918877T ES 2101867 T3 ES2101867 T3 ES 2101867T3
- Authority
- ES
- Spain
- Prior art keywords
- double
- formation
- dna
- diagnostic applications
- ties
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/520,321 US5223414A (en) | 1990-05-07 | 1990-05-07 | Process for nucleic acid hybridization and amplification |
| US07/755,462 US5273881A (en) | 1990-05-07 | 1991-09-04 | Diagnostic applications of double D-loop formation |
| US91079192A | 1992-07-09 | 1992-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2101867T3 true ES2101867T3 (es) | 1997-07-16 |
Family
ID=27414753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92918877T Expired - Lifetime ES2101867T3 (es) | 1990-05-07 | 1992-09-04 | Aplicaciones diagnosticas de la formacion de lazos d dobles. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5670316A (https=) |
| EP (1) | EP0612352B1 (https=) |
| JP (1) | JP2745816B2 (https=) |
| KR (1) | KR100245284B1 (https=) |
| AT (1) | ATE153707T1 (https=) |
| AU (1) | AU661505B2 (https=) |
| CA (1) | CA2116215C (https=) |
| DE (1) | DE69220084T2 (https=) |
| DK (1) | DK0612352T3 (https=) |
| ES (1) | ES2101867T3 (https=) |
| FI (1) | FI941016L (https=) |
| NO (1) | NO313557B1 (https=) |
| WO (1) | WO1993005178A1 (https=) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5506098A (en) * | 1991-09-04 | 1996-04-09 | Daikin Industries, Ltd. | In situ hybridization method |
| JPH07506252A (ja) * | 1992-04-24 | 1995-07-13 | エス・アール・アイ・インターナシヨナル | 真核細胞内でのイン・ビボ相同配列ターゲッティング |
| US5929043A (en) * | 1995-01-31 | 1999-07-27 | Pangene Corporation | Recombinase mediated DNA therapies |
| FR2737502B1 (fr) * | 1995-07-31 | 1997-10-24 | Genset Sa | Procede de detection d'acides nucleiques utilisant des sondes nucleotidiques permettant a la fois une capture specifique et une detection |
| AU712873B2 (en) * | 1996-08-29 | 1999-11-18 | Tapestry Pharmaceuticals, Inc. | Methods for targeting, enriching, detecting and/or isolating target nucleic acidsequence using reca-like recombinase |
| JP3891620B2 (ja) * | 1996-11-14 | 2007-03-14 | 株式会社アイシン・コスモス研究所 | ヘアピン型構造の核酸プローブ分子、及び該核酸プローブ分子を利用した核酸検出方法 |
| US5948653A (en) * | 1997-03-21 | 1999-09-07 | Pati; Sushma | Sequence alterations using homologous recombination |
| US6342350B1 (en) * | 1997-09-05 | 2002-01-29 | The General Hospital Corporation | Alpha-2-macroglobulin diagnostic test |
| AU762766B2 (en) | 1997-12-11 | 2003-07-03 | Napro Biotherapeutics, Inc. | The use of consensus sequences for targeted homologous gene isolation and recombination in gene families |
| WO1999050446A1 (de) * | 1998-04-01 | 1999-10-07 | Wolfrum Juergen | Verfahren und vorrichtung zur quantifizierung von dna und rna |
| US6287772B1 (en) * | 1998-04-29 | 2001-09-11 | Boston Probes, Inc. | Methods, kits and compositions for detecting and quantitating target sequences |
| US6541227B1 (en) * | 1998-10-12 | 2003-04-01 | Aisin Seiki Kabushiki Kaisha | Preparation of labeled DNA |
| JP4265028B2 (ja) * | 1999-04-14 | 2009-05-20 | アイシン精機株式会社 | 二本鎖ｄｎａの特異的切断方法およびそのためのキット |
| US6977295B2 (en) | 1999-04-21 | 2005-12-20 | Invitrogen Corporation | Locked nucleic acid hybrids and methods of use |
| CA2394974A1 (en) * | 1999-12-21 | 2001-06-28 | Ortho-Clinical Diagnostics, Inc. | Method of nucleic acid detection using target-specific assays |
| WO2001048249A2 (en) * | 1999-12-28 | 2001-07-05 | Pangene Corporation | Recombinase mediated gene chip detection |
| WO2002077286A1 (en) * | 2001-02-21 | 2002-10-03 | Gene Check, Inc. | Mutation detection using muts and reca |
| WO2002079495A2 (en) | 2001-03-27 | 2002-10-10 | University Of Delaware | Genomics applications for modified oligonucleotides |
| EP1386006B1 (en) | 2001-04-20 | 2008-05-28 | The Penn State Research Foundation | Methods for nucleic acid manipulation |
| US7468244B2 (en) | 2001-09-27 | 2008-12-23 | University Of Delaware | Polymorphism detection and separation |
| EP1446502A4 (en) * | 2001-09-28 | 2005-02-09 | Univ Delaware | DETECTION AND SEPARATION OF POLYMORPHISMS |
| US7244562B2 (en) * | 2001-11-01 | 2007-07-17 | Gene Check, Inc. | RecA assisted detection of mutations, single nucleotide polymorphisms and specific sequences |
| US7399590B2 (en) * | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| DE60322044D1 (de) * | 2002-02-21 | 2008-08-21 | Asm Scient Inc | Rekombinase-polymerase-amplifikation |
| US8030000B2 (en) | 2002-02-21 | 2011-10-04 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| JPWO2003100095A1 (ja) * | 2002-05-08 | 2005-09-22 | アークレイ株式会社 | 標的核酸の検出法 |
| US20040053399A1 (en) * | 2002-07-17 | 2004-03-18 | Rudolf Gilmanshin | Methods and compositions for analyzing polymers using chimeric tags |
| EP1613768A4 (en) * | 2003-03-11 | 2006-05-31 | Gene Check Inc | RECA-SUPPORTED ALLELSPECIFIC OLIGONUCLEOTIDE EXTENSION PROCESS |
| JP2007501003A (ja) * | 2003-08-01 | 2007-01-25 | ユー．エス． ジェノミクス， インコーポレイテッド | 非切断条件下で核酸を分析するための配列特異的エンドヌクレアーゼの使用に関連した方法および組成物 |
| WO2005017205A2 (en) * | 2003-08-04 | 2005-02-24 | U. S. Genomics, Inc. | Nucleic acid mapping using linear analysis |
| ES2425354T3 (es) * | 2004-06-01 | 2013-10-14 | Alere San Diego, Inc. | Amplificación por recombinasa-polimerasa |
| JP2006055065A (ja) * | 2004-08-19 | 2006-03-02 | Toyo Kohan Co Ltd | 非対称ｐｃｒを用いた核酸の検出方法、ポリヌクレオチドプローブ、それを固定するプローブ固定化担体およびキット |
| WO2006051988A1 (ja) * | 2004-11-15 | 2006-05-18 | Riken | 核酸の増幅方法 |
| JP5027126B2 (ja) | 2005-07-25 | 2012-09-19 | アリーア サン ディエゴ， インコーポレイテッド | リコンビナーゼポリメラーゼ増幅を多重化するための方法 |
| US20090064377A1 (en) * | 2005-09-29 | 2009-03-05 | Daphne Yvette Rainey-Wittich | Method and means for targeted nucleotide exchange |
| US20070202522A1 (en) * | 2006-02-27 | 2007-08-30 | Salinas Frank G | Isothermal screening of tumor cell related nucleic acids |
| US20080003600A1 (en) * | 2006-02-27 | 2008-01-03 | Salinas Frank G | Isothermal screening of breast cancer related nucleic acid |
| US20090061413A1 (en) * | 2006-02-27 | 2009-03-05 | Salinas Frank G | Isothermal screening of hiv-1 related nucleic acids |
| US20080220421A1 (en) * | 2006-02-27 | 2008-09-11 | Salinas Frank G | Isothermal screening for nucleic acids associated with diseases and conditions of the gi tract |
| US8071308B2 (en) | 2006-05-04 | 2011-12-06 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| JP5847076B2 (ja) | 2009-05-20 | 2016-01-20 | バイオサイト インコーポレイテッド | Ｄｎａグリコシラーゼ／リアーゼおよびａｐエンドヌクレアーゼ基質 |
| ES3022638T3 (en) | 2009-06-05 | 2025-05-28 | Abbott Diagnostics Scarborough Inc | Recombinase polymerase amplification reagents |
| CN102859003B (zh) | 2010-03-08 | 2014-07-30 | 达纳-法伯癌症研究院有限公司 | 使用参考封闭序列的全cold-pcr富集 |
| EP3333269B1 (en) | 2011-03-31 | 2021-05-05 | Dana-Farber Cancer Institute, Inc. | Methods to enable multiplex cold-pcr |
| BR112013025758B1 (pt) | 2011-04-07 | 2021-04-06 | Abbott Diagnostics Scarborough, Inc. | Monitoramento de misturas de amplificação de recombinase polimerase |
| CN114854832A (zh) | 2012-04-19 | 2022-08-05 | 生命技术公司 | 核酸扩增 |
| EP3095879B1 (en) | 2012-04-19 | 2018-09-19 | Life Technologies Corporation | Nucleic acid amplification |
| US20150197787A1 (en) * | 2012-08-02 | 2015-07-16 | Qiagen Gmbh | Recombinase mediated targeted dna enrichment for next generation sequencing |
| EP2895620B1 (en) | 2012-09-11 | 2017-08-02 | Life Technologies Corporation | Nucleic acid amplification |
| WO2014043143A1 (en) | 2012-09-11 | 2014-03-20 | Life Technologies Corporation | Nucleic acid amplification |
| CN106103713B (zh) | 2014-02-03 | 2021-05-28 | 赛默飞世尔科技波罗的海封闭股份公司 | 用于经控制dna片段化的方法 |
| CN106574305B (zh) | 2014-06-13 | 2021-03-02 | 生命技术公司 | 多重核酸扩增 |
| JP6698708B2 (ja) | 2015-06-09 | 2020-05-27 | ライフ テクノロジーズ コーポレーション | 分子タグ付けのための方法、システム、組成物、キット、装置、及びコンピュータ可読媒体 |
| CA2990846C (en) * | 2015-06-24 | 2023-09-26 | Dana-Farber Cancer Institute, Inc. | Selective degradation of wild-type dna and enrichment of mutant alleles using nuclease |
| US20180363037A1 (en) | 2015-12-09 | 2018-12-20 | Life Technologies Corporation | Detection and quantification of nucleic acid molecules associated with a surface |
| US10626383B2 (en) | 2016-01-15 | 2020-04-21 | Thermo Fisher Scientific Baltics Uab | Thermophilic DNA polymerase mutants |
| US11268117B2 (en) | 2016-06-10 | 2022-03-08 | Life Technologies Corporation | Methods and compositions for nucleic acid amplification |
| WO2018071522A1 (en) | 2016-10-11 | 2018-04-19 | Life Technologies Corporation | Rapid amplification of nucleic acids |
| US11371090B2 (en) | 2016-12-12 | 2022-06-28 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for molecular barcoding of DNA molecules prior to mutation enrichment and/or mutation detection |
| US11542540B2 (en) | 2017-06-16 | 2023-01-03 | Life Technologies Corporation | Control nucleic acids, and compositions, kits, and uses thereof |
| US11618891B2 (en) | 2017-06-26 | 2023-04-04 | Thermo Fisher Scientific Baltics Uab | Thermophilic DNA polymerase mutants |
| DE102017114537A1 (de) * | 2017-06-29 | 2019-01-03 | Endress+Hauser Conducta Gmbh+Co. Kg | Sensormembran, Sensorkappe und optischer Sensor |
| EP4310196A3 (en) | 2017-11-07 | 2024-04-24 | Life Technologies Corporation | Methods and compositions for manipulating nucleic acids |
| US12226745B2 (en) | 2017-11-07 | 2025-02-18 | Life Technologies Corporation | Methods and compositions for manipulating nucleic acids |
| WO2020227031A1 (en) | 2019-05-03 | 2020-11-12 | Life Technologies Corporation | Methods and compositions for manipulating nucleic acids |
| KR20220062302A (ko) | 2019-08-21 | 2022-05-16 | 라이프 테크놀로지스 코포레이션 | 시퀀싱을 위한 시스템 및 방법 |
| WO2022104272A1 (en) | 2020-11-16 | 2022-05-19 | Life Technologies Corporation | System and method for sequencing |
| NL2033124B1 (en) * | 2022-09-23 | 2024-03-29 | Rapidemic B V | Methods and device for multiple-label nucleic acid amplification and detection |
| WO2025144744A1 (en) | 2023-12-29 | 2025-07-03 | Life Technologies Corporation | Enrichment of clonal substrates |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI63596C (fi) * | 1981-10-16 | 1983-07-11 | Orion Yhtymae Oy | Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser |
| US4766062A (en) * | 1984-05-07 | 1988-08-23 | Allied Corporation | Displacement polynucleotide assay method and polynucleotide complex reagent therefor |
| CA1254114A (en) * | 1984-05-07 | 1989-05-16 | Allied Corporation | Displacement polynucleotide assay employing recombination protein and diagnostic kit |
| JPS61502282A (ja) * | 1984-06-01 | 1986-10-09 | ナショナル・バイオメディカル・リサ−チ・ファウンデ−ション | 酵素剤を用いた触媒作用による核酸交雑方法 |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| EP0236491A1 (en) * | 1985-09-18 | 1987-09-16 | Yale University | RecA NUCLEOPROTEIN FILAMENT AND METHODS |
| US4888274A (en) * | 1985-09-18 | 1989-12-19 | Yale University | RecA nucleoprotein filament and methods |
| AU2735988A (en) * | 1987-12-21 | 1989-07-13 | Amoco Corporation | Target and background capture methods with amplification for affinity assays |
| EP0322311B1 (en) * | 1987-12-21 | 1994-03-23 | Applied Biosystems, Inc. | Method and kit for detecting a nucleic acid sequence |
| US5273881A (en) * | 1990-05-07 | 1993-12-28 | Daikin Industries, Ltd. | Diagnostic applications of double D-loop formation |
| US5223414A (en) * | 1990-05-07 | 1993-06-29 | Sri International | Process for nucleic acid hybridization and amplification |
| US5506098A (en) * | 1991-09-04 | 1996-04-09 | Daikin Industries, Ltd. | In situ hybridization method |
-
1992
- 1992-09-04 US US08/199,317 patent/US5670316A/en not_active Expired - Fee Related
- 1992-09-04 EP EP92918877A patent/EP0612352B1/en not_active Expired - Lifetime
- 1992-09-04 AT AT92918877T patent/ATE153707T1/de not_active IP Right Cessation
- 1992-09-04 FI FI941016A patent/FI941016L/fi unknown
- 1992-09-04 CA CA002116215A patent/CA2116215C/en not_active Expired - Fee Related
- 1992-09-04 ES ES92918877T patent/ES2101867T3/es not_active Expired - Lifetime
- 1992-09-04 DE DE69220084T patent/DE69220084T2/de not_active Expired - Fee Related
- 1992-09-04 JP JP5505113A patent/JP2745816B2/ja not_active Expired - Fee Related
- 1992-09-04 KR KR1019940700724A patent/KR100245284B1/ko not_active Expired - Fee Related
- 1992-09-04 WO PCT/JP1992/001135 patent/WO1993005178A1/en not_active Ceased
- 1992-09-04 AU AU25401/92A patent/AU661505B2/en not_active Ceased
- 1992-09-04 DK DK92918877.9T patent/DK0612352T3/da active
-
1994
- 1994-03-03 NO NO19940744A patent/NO313557B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO940744L (https=) | 1994-05-02 |
| FI941016A7 (fi) | 1994-05-03 |
| EP0612352B1 (en) | 1997-05-28 |
| DE69220084D1 (de) | 1997-07-03 |
| KR100245284B1 (ko) | 2000-03-02 |
| CA2116215A1 (en) | 1993-03-05 |
| US5670316A (en) | 1997-09-23 |
| JPH06510201A (ja) | 1994-11-17 |
| NO313557B1 (no) | 2002-10-21 |
| AU2540192A (en) | 1993-04-05 |
| CA2116215C (en) | 1998-12-22 |
| ATE153707T1 (de) | 1997-06-15 |
| WO1993005178A1 (en) | 1993-03-18 |
| DE69220084T2 (de) | 1997-09-11 |
| FI941016L (fi) | 1994-05-03 |
| EP0612352A1 (en) | 1994-08-31 |
| JP2745816B2 (ja) | 1998-04-28 |
| DK0612352T3 (da) | 1997-06-30 |
| NO940744D0 (no) | 1994-03-03 |
| AU661505B2 (en) | 1995-07-27 |
| FI941016A0 (fi) | 1994-03-03 |
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| FG2A | Definitive protection |
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