ES8504807A1 - Procedimiento para preparar nuevas 4-fenil-tetrahidrofurano (2, 3-c) piridinas - Google Patents

Procedimiento para preparar nuevas 4-fenil-tetrahidrofurano (2, 3-c) piridinas

Info

Publication number
ES8504807A1
ES8504807A1 ES531927A ES531927A ES8504807A1 ES 8504807 A1 ES8504807 A1 ES 8504807A1 ES 531927 A ES531927 A ES 531927A ES 531927 A ES531927 A ES 531927A ES 8504807 A1 ES8504807 A1 ES 8504807A1
Authority
ES
Spain
Prior art keywords
furano
pyridines
tetrahydro
phenyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES531927A
Other languages
English (en)
Other versions
ES531927A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Publication of ES8504807A1 publication Critical patent/ES8504807A1/es
Publication of ES531927A0 publication Critical patent/ES531927A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 4-FENIL-TETRAHIDROFURANO 2,3-CPIRIDINAS Y DE SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R, R, R Y R PUEDEN SER VARIOS RADICALES.CONSISTE EN LA REACCION DE UNA 4,5,6,7-TETRAHIDRO-4-HIDROXIFURANO 2,3-CPIRIDINA, DE FORMULA (II), CON UN DERIVADO BENCNICO DE FORMULA (III), EN LAS QUE R, R, R Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I).ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIDEPRESIVOS Y POR SU EFECTO TIMOLOGICO Y EXCITADOR DEL SISTEMA NERVIOSO CENTRAL.
ES531927A 1983-04-27 1984-04-26 Procedimiento para preparar nuevas 4-fenil-tetrahidrofurano (2, 3-c) piridinas Granted ES531927A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833315157 DE3315157A1 (de) 1983-04-27 1983-04-27 4-phenyl-tetrahydro-furano-pyridine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen

Publications (2)

Publication Number Publication Date
ES8504807A1 true ES8504807A1 (es) 1985-04-16
ES531927A0 ES531927A0 (es) 1985-04-16

Family

ID=6197430

Family Applications (3)

Application Number Title Priority Date Filing Date
ES531927A Granted ES531927A0 (es) 1983-04-27 1984-04-26 Procedimiento para preparar nuevas 4-fenil-tetrahidrofurano (2, 3-c) piridinas
ES538617A Granted ES538617A0 (es) 1983-04-27 1984-12-14 Procedimiento para preparar nuevas 4-fenil-tetrahidrofurano-(2,3-c)priridinas
ES538616A Expired ES8602001A1 (es) 1983-04-27 1984-12-14 Procedimiento para preparar nuevas 4-fenil-tetrahidrofurano-(2,3-c)priridinas

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES538617A Granted ES538617A0 (es) 1983-04-27 1984-12-14 Procedimiento para preparar nuevas 4-fenil-tetrahidrofurano-(2,3-c)priridinas
ES538616A Expired ES8602001A1 (es) 1983-04-27 1984-12-14 Procedimiento para preparar nuevas 4-fenil-tetrahidrofurano-(2,3-c)priridinas

Country Status (17)

Country Link
US (1) US4636510A (es)
EP (1) EP0123998A3 (es)
JP (1) JPS59205383A (es)
KR (1) KR840008357A (es)
AU (1) AU566073B2 (es)
DE (1) DE3315157A1 (es)
DK (1) DK209384A (es)
ES (3) ES531927A0 (es)
FI (1) FI841615A (es)
GB (1) GB2138817B (es)
GR (1) GR79573B (es)
IL (1) IL71661A0 (es)
NO (1) NO841661L (es)
NZ (1) NZ207943A (es)
PH (1) PH19896A (es)
PT (1) PT78487B (es)
ZA (1) ZA843084B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2566775B1 (fr) * 1984-06-27 1986-10-31 Synthelabo Derives de tetrahydro-4,5,6,7 furo ou 1h-pyrrolo(2,3-c)pyridine, leur preparation et leur application en therapeutique
US4572911A (en) * 1984-08-02 1986-02-25 Mcneilab, Inc. Hexahydroindolinzine compounds, pharmaceutical compositions and methods and intermediates
IT1230768B (it) * 1989-02-21 1991-10-29 Agrimont Spa Derivati del 3,4 deidro piperidin 5 one ad attivita' erbicida.
US5221792A (en) * 1989-02-21 1993-06-22 Agrimont S.P.A. Derivatives from 3,4-dehydro-piperidin-5-one exhibiting a herbicidal activity
CA2200469A1 (en) * 1994-10-11 1996-04-18 Takeda Chemical Industries, Ltd. Condensed compounds, their production and use
EP1430042A2 (en) 2001-09-25 2004-06-23 SmithKline Beecham Corporation Bicyclic heterocycles as rxr ligands
JP2007537296A (ja) * 2004-05-14 2007-12-20 アボット・ラボラトリーズ 治療薬としてのキナーゼ阻害薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2358150A1 (fr) * 1976-07-13 1978-02-10 Parcor Nouvelles thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application
AT368504B (de) * 1977-10-15 1982-10-25 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer 4-phenyl-thieno- (2,3-c)-piperidine
FR2414048A1 (fr) * 1978-01-04 1979-08-03 Parcor Benzofuro (2,3-c) pyridines, leur procede de preparation et leur application en therapeutique
US4282227A (en) * 1980-05-22 1981-08-04 Smithkline Corporation Renal vasodilating 3,4-dihydroxyphenyltetrahydrothienopyridines

Also Published As

Publication number Publication date
NZ207943A (en) 1986-10-08
GB8410840D0 (en) 1984-06-06
PH19896A (en) 1986-08-13
PT78487A (de) 1984-05-01
AU2743684A (en) 1984-11-01
FI841615A (fi) 1984-10-28
EP0123998A2 (de) 1984-11-07
GB2138817A (en) 1984-10-31
KR840008357A (ko) 1984-12-14
ES8602002A1 (es) 1985-11-01
GB2138817B (en) 1986-10-01
DK209384D0 (da) 1984-04-26
IL71661A0 (en) 1984-07-31
JPS59205383A (ja) 1984-11-20
US4636510A (en) 1987-01-13
ES538616A0 (es) 1985-11-01
DE3315157A1 (de) 1984-10-31
DK209384A (da) 1984-10-28
GR79573B (es) 1984-10-30
ZA843084B (en) 1985-12-24
PT78487B (de) 1986-07-22
ES531927A0 (es) 1985-04-16
ES538617A0 (es) 1985-11-01
AU566073B2 (en) 1987-10-08
EP0123998A3 (de) 1987-09-30
FI841615A0 (fi) 1984-04-25
ES8602001A1 (es) 1985-11-01
NO841661L (no) 1984-10-29

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