ES2100131A1 - Procedimiento enzimatico de obtencion de beta-d-galactopiranosil-d-xilosas utilizables para la evaluacion diagnostica de la lactasa intestinal. - Google Patents

Procedimiento enzimatico de obtencion de beta-d-galactopiranosil-d-xilosas utilizables para la evaluacion diagnostica de la lactasa intestinal.

Info

Publication number
ES2100131A1
ES2100131A1 ES9502185A ES9502185A ES2100131A1 ES 2100131 A1 ES2100131 A1 ES 2100131A1 ES 9502185 A ES9502185 A ES 9502185A ES 9502185 A ES9502185 A ES 9502185A ES 2100131 A1 ES2100131 A1 ES 2100131A1
Authority
ES
Spain
Prior art keywords
beta
galactopyranosyl
xyloses
evaluation
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES9502185A
Other languages
English (en)
Other versions
ES2100131B1 (es
Inventor
Reyes Juan Jose Aragon
Vicinay Francisco J Canada
Alvarez Al Fernandez-Mayorales
Alvarez Rosa Lopez
Lomas Manuel Martin
Torregroza Daniel Villanueva
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES09502185A priority Critical patent/ES2100131B1/es
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to EA199700097A priority patent/EA000684B1/ru
Priority to PT96937342T priority patent/PT819764E/pt
Priority to NZ321607A priority patent/NZ321607A/xx
Priority to HU9801439A priority patent/HUP9801439A3/hu
Priority to CA002209927A priority patent/CA2209927C/en
Priority to CNB961923989A priority patent/CN1220779C/zh
Priority to AT96937342T priority patent/ATE214740T1/de
Priority to BR9607092A priority patent/BR9607092A/pt
Priority to KR1019970704676A priority patent/KR19980701287A/ko
Priority to US08/875,043 priority patent/US5994092A/en
Priority to EP96937342A priority patent/EP0819764B1/en
Priority to DE69619973T priority patent/DE69619973T2/de
Priority to SK1001-97A priority patent/SK100197A3/sk
Priority to CZ972527A priority patent/CZ252797A3/cs
Priority to ES96937342T priority patent/ES2176505T3/es
Priority to PL96321257A priority patent/PL321257A1/xx
Priority to AU74977/96A priority patent/AU702329B2/en
Priority to JP09517877A priority patent/JP3036848B2/ja
Priority to PCT/ES1996/000208 priority patent/WO1997017464A1/es
Publication of ES2100131A1 publication Critical patent/ES2100131A1/es
Priority to NO973159A priority patent/NO973159L/no
Priority to MXPA/A/1997/005109A priority patent/MXPA97005109A/es
Publication of ES2100131B1 publication Critical patent/ES2100131B1/es
Application granted granted Critical
Priority to JP11289464A priority patent/JP2000106898A/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/12—Disaccharides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO ENZIMATICO DE OBTENCION DE BE-D-GALACTOPIRANOSIL-D-XILOSAS UTILIZABLES PARA LA EVALUACION DIAGNOSTICA DE LA LACTASA INTESTINAL. EL OBJETO DE LA PRESENTE INVENCION ES UN PROCEDIMIENTO ENZIMATICO DE OBTENCION DE BE-D-GALACTOPIRANOSIL-D-XILOSAS UTILIZABLES PARA LA EVALUACION DIAGNOSTICA DE LA LACTASA INTESTINAL. DICHO PROCEDIMIENTO IMPLICA UNA SOLA ETAPA DE REACCION Y EL EMPLEO DE SUSTRATOS ASEQUIBLES Y UN BIOCATALIZADOR TAMBIEN ASEQUIBLE Y DE BAJO COSTO. LA UTILIZACION DE LOS COMPUESTOS OBTENIDOS COMO SUSTRATOS DE LA LACTASA INTESTINAL, ORIGINANDO GALACTOSA Y XILOSA COMO PRODUCTOS DE HIDROLISIS, PERMITE LA EVALUACION "IN VIVO" DE LA ACTIVIDAD LACTASA INTESTINAL LO QUE PUEDE TENER PARTICULAR APLICABILIDAD EN INDIVIDUOS LACTANTES EN QUE SE SOSPECHE LA EXISTENCIA DE UNA DEFICIENCIA EN ESTE ENZIMA.
ES09502185A 1995-11-08 1995-11-08 Procedimiento enzimatico de obtencion de beta-d-galactopiranosil-d-xilosas utilizables para la evaluacion diagnostica de la lactasa intestinal. Expired - Fee Related ES2100131B1 (es)

Priority Applications (23)

Application Number Priority Date Filing Date Title
ES09502185A ES2100131B1 (es) 1995-11-08 1995-11-08 Procedimiento enzimatico de obtencion de beta-d-galactopiranosil-d-xilosas utilizables para la evaluacion diagnostica de la lactasa intestinal.
ES96937342T ES2176505T3 (es) 1995-11-08 1996-11-08 Uso de o-beta-d-galactopiranosil-d-xilosas para la preparacion de composiciones y soluciones destinadas para la evaluacion de la lactasa intestinal, y procedimiento para su obtencion.
SK1001-97A SK100197A3 (en) 1995-11-08 1996-11-08 Use of beta-d-galactopyranosyl-d-xylose and enzymatic method for producing beta-galactopyranosyl-d-xylose
HU9801439A HUP9801439A3 (en) 1995-11-08 1996-11-08 Use of beta-d-galactopyranosyl-d-xyloses for the preparation of compositions and solutions intended to the evaluation of intestinal lactase, and production process of the said compds.
CA002209927A CA2209927C (en) 1995-11-08 1996-11-08 Use of o-.beta.-d-galactopyranosyl-d-xyloses for the preparation of compositions and solutions for the evaluation of intestinal lactase, and production process
CNB961923989A CN1220779C (zh) 1995-11-08 1996-11-08 β－D－吡喃半乳糖基－D－木糖在制备用于测定肠乳糖酶的组合物和溶液中的应用及其生产方法
AT96937342T ATE214740T1 (de) 1995-11-08 1996-11-08 Verwendung von beta-d-galactopyranosyl-d-xylosen zur herstellung von zusammensetzungen und lösungen, die zur bewertung der intestinalen lactoseaktivität bestimmt sind, und herstellungsverfahren
BR9607092A BR9607092A (pt) 1995-11-08 1996-11-08 Uso de b-d-galactopiranosil-d-xilose para a preparação de composições e procedimento enzimático para a produção de b-d- galactopiranosil-d-xiloses
KR1019970704676A KR19980701287A (ko) 1995-11-08 1996-11-08 장내 락타아제의 평가를 위한 조성물과 용액의 제조에 사용되는 β-디이-갈락토피라노실-디이-크실로스의 용도 및 생산방법
US08/875,043 US5994092A (en) 1995-11-08 1996-11-08 Use of β-D-galactopyranosyl-D-xyloses for the preparation of compositions and solutions intended to the evaluation of intestinal lactase, and production process
EP96937342A EP0819764B1 (en) 1995-11-08 1996-11-08 Use of o-beta-d-galactopyranosyl-d-xyloses for the preparation of compositions and solutions intended to the evaluation of intestinal lactase, and production process
DE69619973T DE69619973T2 (de) 1995-11-08 1996-11-08 Verwendung von beta-d-galactopyranosyl-d-xylosen zur herstellung von zusammensetzungen und lösungen, die zur bewertung der intestinalen lactoseaktivität bestimmt sind, und herstellungsverfahren
EA199700097A EA000684B1 (ru) 1995-11-08 1996-11-08 ПРИМЕНЕНИЕ β-D-ГАЛАКТОПИРАНОЗИЛ-D-КСИЛОЗЫ ДЛЯ ПОЛУЧЕНИЯ КОМПОЗИЦИЙ И РАСТВОРОВ, ПРЕДНАЗНАЧЕННЫХ ДЛЯ ОПРЕДЕЛЕНИЯ ЛАКТАЗЫ КИШЕЧНИКА
NZ321607A NZ321607A (en) 1995-11-08 1996-11-08 Use of beta-d-galactopyranosyl-d-xylose for evaluating intestinal lactase and preparatory processes
CZ972527A CZ252797A3 (cs) 1995-11-08 1996-11-08 Použití beta-D-galaktopyranosyl-D-xylosy a způsob jejich výroby
PL96321257A PL321257A1 (en) 1995-11-08 1996-11-08 Application of beta-d-glactopyranosil-d-xyloses in production of compositions and solutions used in assessing intenstinal lactase and method of obtaining them
AU74977/96A AU702329B2 (en) 1995-11-08 1996-11-08 Use of beta-D-galactopyranosyl-D-xyloses for the preparation of compositions and solutions intended to the evaluation of intestinal lactase, and production process
JP09517877A JP3036848B2 (ja) 1995-11-08 1996-11-08 腸ラクターゼの評価を意図した組成物および溶液の製造におけるβ−Ｄ−ガラクトピラノシル−Ｄ−キシロースの使用および製造法
PCT/ES1996/000208 WO1997017464A1 (es) 1995-11-08 1996-11-08 USO DE β-D-GALACTOPIRANOSIL-D-XILOSAS PARA LA PREPARACION DE COMPOSICIONES Y DISOLUCIONES DESTINADAS A LA EVALUACION DE LA LACTASA INTESTINAL, Y PROCEDIMIENTO PARA SU OBTENCION
PT96937342T PT819764E (pt) 1995-11-08 1996-11-08 Utilizacao de o-beta-d-galactopiranosil-d-xiloses para a preparacao de composicoes e solucoes destinadas a avaliacao da lactase intestinal e processo de producao
MXPA/A/1997/005109A MXPA97005109A (es) 1995-11-08 1997-07-08 USO DEß-D-GALACTOPIRANOSIL-D-XILOSAS PARA LA PREPARACION DE COMPOSICIONES Y DISOLUCIONES DESTINADAS A LA EVALUACION DE LA LACTASA INTESTINAL, Y PROCEDIMIENTO PARA SU OBTENCION
NO973159A NO973159L (no) 1995-11-08 1997-07-08 Anvendelse av <beta>-D-galaktopyranosyl-D-xyloser til fremstilling av preparater og opplösninger ment for evaluering av tarmlaktase, og fremstillingsfremgangsmåte
JP11289464A JP2000106898A (ja) 1995-11-08 1999-10-12 腸ラクタ―ゼの評価を意図した組成物および溶液の製造におけるβ―Ｄ―ガラクトピラノシル―Ｄ―キシロ―スの製造法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09502185A ES2100131B1 (es) 1995-11-08 1995-11-08 Procedimiento enzimatico de obtencion de beta-d-galactopiranosil-d-xilosas utilizables para la evaluacion diagnostica de la lactasa intestinal.

Publications (2)

Publication Number Publication Date
ES2100131A1 true ES2100131A1 (es) 1997-06-01
ES2100131B1 ES2100131B1 (es) 1998-02-16

Family

ID=8292102

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09502185A Expired - Fee Related ES2100131B1 (es) 1995-11-08 1995-11-08 Procedimiento enzimatico de obtencion de beta-d-galactopiranosil-d-xilosas utilizables para la evaluacion diagnostica de la lactasa intestinal.
ES96937342T Expired - Lifetime ES2176505T3 (es) 1995-11-08 1996-11-08 Uso de o-beta-d-galactopiranosil-d-xilosas para la preparacion de composiciones y soluciones destinadas para la evaluacion de la lactasa intestinal, y procedimiento para su obtencion.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES96937342T Expired - Lifetime ES2176505T3 (es) 1995-11-08 1996-11-08 Uso de o-beta-d-galactopiranosil-d-xilosas para la preparacion de composiciones y soluciones destinadas para la evaluacion de la lactasa intestinal, y procedimiento para su obtencion.

Country Status (20)

Country Link
US (1) US5994092A (es)
EP (1) EP0819764B1 (es)
JP (2) JP3036848B2 (es)
KR (1) KR19980701287A (es)
CN (1) CN1220779C (es)
AT (1) ATE214740T1 (es)
AU (1) AU702329B2 (es)
BR (1) BR9607092A (es)
CA (1) CA2209927C (es)
CZ (1) CZ252797A3 (es)
DE (1) DE69619973T2 (es)
EA (1) EA000684B1 (es)
ES (2) ES2100131B1 (es)
HU (1) HUP9801439A3 (es)
NO (1) NO973159L (es)
NZ (1) NZ321607A (es)
PL (1) PL321257A1 (es)
PT (1) PT819764E (es)
SK (1) SK100197A3 (es)
WO (1) WO1997017464A1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002103038A1 (es) * 2001-06-18 2002-12-27 Consejo Superior De Investigaciones Cientificas Un procedimiento enzimático para obtener 4-0-b-d galactopiranosil-d-xilosa obtenida deacuerdo con el procedimiento, composiciones que la contienen y su uso en la evaluación de la lactasa intestinal
WO2004035814A1 (es) * 2002-10-16 2004-04-29 Consejo Superior De Investigaciones Científicas Empleo de 4-galactosil-xilosa en humanos para la evaluación in vivo de lactasa intestinal como prueba diagnóstica no invasiva de la deficiencia de este enzima

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2130073B1 (es) * 1997-05-28 2000-04-01 Consejo Superior Investigacion Mejoras en el procedimiento de obtencion de beta-d-galactopiranosil-xilosas utilizables para la evaluacion diagnostica de la lactasa intestinal.
JP2006223268A (ja) * 2005-02-21 2006-08-31 Yakult Honsha Co Ltd ガラクトシル２糖類の製造法
US20110196219A1 (en) * 2010-02-08 2011-08-11 Edmunds Kathleen Fetal Scalp Blood Analyzer
US20110196214A1 (en) * 2010-02-08 2011-08-11 Edmunds Kathleen Fetal Scalp Blood Analyzer
US9128100B2 (en) 2011-01-14 2015-09-08 Venter Pharma, S.L. Non-invasive diagnostic method for the evaluation of intestinal lactase deficiency (hypolactasia)
WO2018100120A1 (en) 2016-11-30 2018-06-07 Elaphe Pogonske Tehnologije D.O.O. Electric machine with a cooling system and a method for cooling an electric machine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2023556A6 (es) * 1990-06-18 1992-01-16 Consejo Superior Investigacion Procedimiento de obtencion de 4-o-beta-d-galactopiranosil-d-xilosa utilizable para la evaluacion diagnostica de la lactasa intestinal.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2834871B2 (ja) * 1990-08-07 1998-12-14 塩水港精糖株式会社 フラクトース含有オリゴ糖の製造法

Patent Citations (1)

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ES2023556A6 (es) * 1990-06-18 1992-01-16 Consejo Superior Investigacion Procedimiento de obtencion de 4-o-beta-d-galactopiranosil-d-xilosa utilizable para la evaluacion diagnostica de la lactasa intestinal.

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
A. RIVERA-SAGREDO et al., "4-O-beta-D-galactopyranosyl-D-xylose: a new synthesis and application to the evaluation of intestinal lactase", CARBOHYDRATE RESEARCH, vol. 228, 10 abril 1992, Amsterdam, NL, pßgs.: 129-135. * todo el documento * *
J.J. ARAGON et al., "Evaluation of rat intestinal lactase in vivo with 4-galactosylxylose", CLINICA CHIMICA ACTA, vol. 210, 30 septiembre 1992, Amsterdam, NL, pßgs.: 221-226 * todo el documento * *
P.A.J. GORIN et al., "The synthesis of beta-galacto- and beta-gluco- pyranosyl disaccharides by Sporobolomyces singularis", Can.J.Chem., vol. 42, n‘ 10, octubre 1964, Ottawa, CA, pßgs.:2307-2317. * todo el documento * *
R. LOPEZ et al., "Enzymic beta-galactosidation of beta-xylopyrano- sides", BIOTECHNOL. LETT., vol. 13, n‘ 10, 1991, pßgs.: 705-710 * todo el documento * *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002103038A1 (es) * 2001-06-18 2002-12-27 Consejo Superior De Investigaciones Cientificas Un procedimiento enzimático para obtener 4-0-b-d galactopiranosil-d-xilosa obtenida deacuerdo con el procedimiento, composiciones que la contienen y su uso en la evaluación de la lactasa intestinal
ES2182703A1 (es) * 2001-06-18 2003-03-01 Consejo Superior Investigacion Un procedimiento enzimatico para obtener 4-0-b-d-galactopiranosil-d-xilosa, 4-o-b-d-galato`piranosil-d-xilosa obtenida de acuerdo con el procedimiento, composiciones que la contienen y su uso en la evaluacion de la lactasa intestinal.
WO2004035814A1 (es) * 2002-10-16 2004-04-29 Consejo Superior De Investigaciones Científicas Empleo de 4-galactosil-xilosa en humanos para la evaluación in vivo de lactasa intestinal como prueba diagnóstica no invasiva de la deficiencia de este enzima
ES2208099A1 (es) * 2002-10-16 2004-06-01 Consejo Sup. De Invest. Cientificas Empleo de 4-galactosil-xilosa en humanos para la evaluacion in vivo de lactasa intestinal como prueba diagnostica no invasiva de la deficiencia de este enzima.

Also Published As

Publication number Publication date
ES2176505T3 (es) 2002-12-01
EP0819764A1 (en) 1998-01-21
KR19980701287A (ko) 1998-05-15
CA2209927A1 (en) 1997-05-15
EA000684B1 (ru) 2000-02-28
NZ321607A (en) 2000-12-22
DE69619973D1 (de) 2002-04-25
PL321257A1 (en) 1997-11-24
DE69619973T2 (de) 2002-11-07
NO973159D0 (no) 1997-07-08
SK100197A3 (en) 1998-02-04
CN1177984A (zh) 1998-04-01
ATE214740T1 (de) 2002-04-15
JP3036848B2 (ja) 2000-04-24
EP0819764B1 (en) 2002-03-20
HUP9801439A2 (hu) 1998-10-28
PT819764E (pt) 2002-09-30
WO1997017464A1 (es) 1997-05-15
JPH10512457A (ja) 1998-12-02
EA199700097A1 (ru) 1997-12-30
CA2209927C (en) 2002-08-13
JP2000106898A (ja) 2000-04-18
CZ252797A3 (cs) 1998-03-18
AU7497796A (en) 1997-05-29
US5994092A (en) 1999-11-30
AU702329B2 (en) 1999-02-18
CN1220779C (zh) 2005-09-28
HUP9801439A3 (en) 2002-01-28
MX9705109A (es) 1998-06-30
NO973159L (no) 1997-09-08
ES2100131B1 (es) 1998-02-16
BR9607092A (pt) 1997-11-11

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