ES2091285T3 - 2-hidroxi-1,2,3-propanotricarboxilato de 3-((5-metil-2-furanil)-metil)-n-(4-piperidinil)-3h-imidazo-(4,5-b)-piridin-2-amina. - Google Patents

2-hidroxi-1,2,3-propanotricarboxilato de 3-((5-metil-2-furanil)-metil)-n-(4-piperidinil)-3h-imidazo-(4,5-b)-piridin-2-amina.

Info

Publication number
ES2091285T3
ES2091285T3 ES91201639T ES91201639T ES2091285T3 ES 2091285 T3 ES2091285 T3 ES 2091285T3 ES 91201639 T ES91201639 T ES 91201639T ES 91201639 T ES91201639 T ES 91201639T ES 2091285 T3 ES2091285 T3 ES 2091285T3
Authority
ES
Spain
Prior art keywords
methyl
furanil
piridin
imidazo
piperidinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91201639T
Other languages
English (en)
Inventor
Alfons Gaston Maria De Knaep
Tonny Franciscus Johanna Nelen
Frans Eduard Janssens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of ES2091285T3 publication Critical patent/ES2091285T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)

Abstract

EL 3-[(5-METIL-2-FURANIL)METIL]-N-(4-PIPERIDINIL)-3H-IMIDAZO[4,5-B] -PIRIDIN-2-AMINA 2-HIDROXI-1, 2, 3-PROPANETRICARBOXILATE ES UNA SAL NUEVA QUE TIENE UNA SATISFACTORIA ESTABILIDAD FISICOQUIMICA Y ES UTIL POR SU ACTIVIDAD ANTIALERGICA. LAS COMPOSICIONES QUE COMPRENDEN DICHA SAL, Y LOS PROCESOS PARA LA PREPARACION Y PURIFICACION DE DICHA SAL Y UN PROCESO PARA LA PREPARACION DE DICHAS COMPOSICIONES.
ES91201639T 1990-07-06 1991-06-27 2-hidroxi-1,2,3-propanotricarboxilato de 3-((5-metil-2-furanil)-metil)-n-(4-piperidinil)-3h-imidazo-(4,5-b)-piridin-2-amina. Expired - Lifetime ES2091285T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54935090A 1990-07-06 1990-07-06

Publications (1)

Publication Number Publication Date
ES2091285T3 true ES2091285T3 (es) 1996-11-01

Family

ID=24192647

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91201639T Expired - Lifetime ES2091285T3 (es) 1990-07-06 1991-06-27 2-hidroxi-1,2,3-propanotricarboxilato de 3-((5-metil-2-furanil)-metil)-n-(4-piperidinil)-3h-imidazo-(4,5-b)-piridin-2-amina.

Country Status (25)

Country Link
EP (1) EP0464927B1 (es)
JP (1) JPH04230382A (es)
KR (1) KR0165894B1 (es)
CN (1) CN1026790C (es)
AT (1) ATE142207T1 (es)
AU (1) AU632949B2 (es)
BG (1) BG60067B2 (es)
CA (1) CA2043564A1 (es)
CZ (1) CZ279435B6 (es)
DE (1) DE69121807T2 (es)
ES (1) ES2091285T3 (es)
FI (1) FI94132C (es)
GR (1) GR3020951T3 (es)
HU (1) HUT58333A (es)
IE (1) IE75695B1 (es)
IL (1) IL98725A (es)
MX (1) MX9100102A (es)
NO (1) NO177854C (es)
NZ (1) NZ238369A (es)
PL (1) PL168719B1 (es)
PT (1) PT98215B (es)
RU (1) RU2047615C1 (es)
SG (1) SG48825A1 (es)
SK (1) SK278127B6 (es)
ZA (1) ZA915241B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6211199B1 (en) 1995-11-17 2001-04-03 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
KR100289063B1 (ko) * 1997-12-17 2001-05-02 정선종 누름스윗치에의한휴대전화기용자동안테나

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484096D1 (de) * 1983-11-30 1991-03-14 Janssen Pharmaceutica Nv Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine.
EP0232937B1 (en) * 1986-02-03 1992-08-19 Janssen Pharmaceutica N.V. Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines
GB8900380D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives

Also Published As

Publication number Publication date
NO912650D0 (no) 1991-07-05
FI913281A0 (fi) 1991-07-05
PT98215B (pt) 1999-01-29
ZA915241B (en) 1993-03-31
CA2043564A1 (en) 1992-01-07
NO177854B (no) 1995-08-28
PL168719B1 (pl) 1996-03-29
ATE142207T1 (de) 1996-09-15
EP0464927A3 (en) 1992-04-08
NZ238369A (en) 1993-07-27
AU632949B2 (en) 1993-01-14
BG60067B2 (en) 1993-09-30
NO177854C (no) 1995-12-06
HUT58333A (en) 1992-02-28
CN1058020A (zh) 1992-01-22
KR920002597A (ko) 1992-02-28
IE912362A1 (en) 1992-01-15
FI913281A (fi) 1992-01-07
IL98725A (en) 1995-07-31
DE69121807D1 (de) 1996-10-10
EP0464927A2 (en) 1992-01-08
GR3020951T3 (en) 1996-12-31
NO912650L (no) 1992-01-07
PT98215A (pt) 1992-06-30
IL98725A0 (en) 1992-07-15
SK278127B6 (en) 1996-02-07
AU8020691A (en) 1992-01-09
EP0464927B1 (en) 1996-09-04
MX9100102A (es) 1992-02-28
CN1026790C (zh) 1994-11-30
FI94132C (fi) 1995-07-25
KR0165894B1 (ko) 1999-01-15
JPH04230382A (ja) 1992-08-19
PL290956A1 (en) 1992-06-26
HU912284D0 (en) 1991-12-30
FI94132B (fi) 1995-04-13
DE69121807T2 (de) 1997-01-23
IE75695B1 (en) 1997-09-10
CZ279435B6 (cs) 1995-04-12
RU2047615C1 (ru) 1995-11-10
CS198791A3 (en) 1992-03-18
SG48825A1 (en) 1998-05-18

Similar Documents

Publication Publication Date Title
ATE269290T1 (de) Benzoylderivate
MX9304647A (es) 7-(sustituido)-9-[(glicilo sustituido)amido]-6-desmetil-6-desoxitetraciclinas y metodo para su produccion.
MX9200817A (es) Derivados de piranil cianoguanidina y proceso para su preparacion.
ES2070660B1 (es) Un procedimiento para la preparacion de 2,5-damino-3-hidroxihexanos sustituidos, utiles como inhibidores de proteasas retrovirales.
ES2062374T3 (es) Heteroarilpiperazinas, agentes antipsicoticos.
DK365184A (da) 1,8-naphthyridinderivater eller estre eller salte deraf, deres fremstilling og anvendelse som farmaceutika
TW333527B (en) Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them
AR241082A1 (es) Nuevos derivados de pirazol utiles como agentes herbicidas, las composiciones herbicidas que los contienen y los procedimientos para producir estos derivados de pirazol".
NO306930B1 (no) Anvendelse av 2-amino-6-n-propylamino-4,5,6,7- tetrahydrobenzotiazol (Pramipexol) som et antidepressivt middel
FI98067C (fi) Uusia alkyleenidiammoniumdiklavulanaattijohdannaisia, menetelmä niidenvalmistamiseksi samoin kuin niiden käyttö kalvulaanihapon puhdistamiseksi
ES2091285T3 (es) 2-hidroxi-1,2,3-propanotricarboxilato de 3-((5-metil-2-furanil)-metil)-n-(4-piperidinil)-3h-imidazo-(4,5-b)-piridin-2-amina.
FI844333L (fi) 11-substituerade 5h,11h-pyrrolo/2,1-c/ /1,4/benzoxazepiner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
ATE107308T1 (de) Mevalonolactone vom thienopyridin-typ.
ES2117132T3 (es) Sales de desferrioxamina-b y su uso como queladores de hierro eficaces por via oral.
DK0746551T3 (da) Optisk rene 4-aryl-2-hydroxytetronsyrer
DK520787A (da) Terapeutisk middel indeholdende propentofyllin eller derivater deraf til brug ved behandling af peptisk ulcus
ES2195500T3 (es) Dereivados del 2-indanometanol y su utilizacion a titulo de ingredientes perfumantes.
AR032373A2 (es) Intermediarios para preparar 3-(1-piperazinil)-1,2-benzoisotiazol.
FI932691A (fi) Nya benzyl- och benzhydrylalkoholer
NO883502D0 (no) Fremgangsmaate ved fjerning av oskygen fra industrivann ved bruk av morfolinoheksose-redukton.
ES2124277T3 (es) Heteroarenilpiperazinas, un procedimiento para su preparacion y su uso como medicamentos.
FI973206A0 (fi) Menetelmä välituotteina käyttökelpoisten halogeeniasetamidijohdannaisten valmistamiseksi
FI892731A (fi) Foerfarande foer framstaellning av nya antiallergiska medel.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 464927

Country of ref document: ES