ES2085192A1 - Composiciones cosmeticas despigmentantes a base de acido cafeico. - Google Patents
Composiciones cosmeticas despigmentantes a base de acido cafeico.Info
- Publication number
- ES2085192A1 ES2085192A1 ES09150019A ES9150019A ES2085192A1 ES 2085192 A1 ES2085192 A1 ES 2085192A1 ES 09150019 A ES09150019 A ES 09150019A ES 9150019 A ES9150019 A ES 9150019A ES 2085192 A1 ES2085192 A1 ES 2085192A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical
- caffeic acid
- acid base
- cosmetic
- depigmentation compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/926—Topical chemical, e.g. cosmetic or sunscreen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
COMPOSICIONES COSMETICAS DESPIGMENTANTES A BASE DE ACIDO CAFEICO, QUE CONTIENEN, COMO INGREDIENTE ACTIVO, ACIDO CAFEICO O UNO DE SUS ESTERES O AMIDAS, EVENTUALMENTE EN ASOCIACION CON LA HIDROQUINONA O UNO DE SUS ETERES, EL ACIDO COJICO O UNA SAL HIDROSOLUBLE DE COBRE. ESTA COMPOSICION, APLICADA SOBRE LA PIEL, TIENE UNA ACCION DESPIGMENTANTE. LA MISMA ES UTILIZABLE EN PARTICULAR EN LOS CASOS DE HIPERPIGMENTACION PATOLOGICA O ACCIDENTAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8913774A FR2653336B1 (fr) | 1989-10-20 | 1989-10-20 | Composition pharmaceutique et cosmetiques depigmentantes a base d'acide cafeique. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2085192A1 true ES2085192A1 (es) | 1996-05-16 |
ES2085192B1 ES2085192B1 (es) | 1997-02-01 |
Family
ID=9386619
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09150019A Expired - Fee Related ES2085192B1 (es) | 1989-10-20 | 1990-10-19 | Composiciones cosmeticas despigmentantes a base de acido cafeico. |
Country Status (18)
Country | Link |
---|---|
US (1) | US5164185A (es) |
EP (1) | EP0450040B1 (es) |
JP (1) | JP2659618B2 (es) |
AR (1) | AR244545A1 (es) |
AT (1) | ATE200977T1 (es) |
AU (1) | AU638768B2 (es) |
BE (1) | BE1003833A3 (es) |
BR (1) | BR9006960A (es) |
CA (1) | CA2044269C (es) |
CH (1) | CH682129A5 (es) |
DE (1) | DE69033731T2 (es) |
ES (1) | ES2085192B1 (es) |
FR (1) | FR2653336B1 (es) |
GB (1) | GB2244005B (es) |
IT (1) | IT1251741B (es) |
MX (1) | MX173203B (es) |
WO (1) | WO1991005543A1 (es) |
ZA (1) | ZA908398B (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69321285T2 (de) * | 1992-05-15 | 1999-03-04 | Shiseido Co Ltd | Äusserliches Hautpräparat |
FR2693105B1 (fr) * | 1992-07-01 | 1994-09-02 | Oreal | Composition cosmétique et/ou dermatologique à action dépigmentante contenant un acide di- ou tri-caféoylquinique ou un mélange de ceux-ci. |
FR2697159B1 (fr) * | 1992-10-22 | 1995-01-13 | Oreal | Composition cosmétique ou dermo-pharmaceutique contenant en association un lauroylméthionate d'un amino acide basique et au moins un polyphénol. |
FR2699080B1 (fr) * | 1992-12-11 | 1995-04-07 | Lvmh Rech | Utilisation d'un extrait de Simarouba pour l'atténuation des taches pigmentaires cutanées ou pour renforcer la fonction protectrice de la peau, ou pour la préparation d'un milieu de culture de cellules de peau, et composition ainsi obtenue. |
FR2699072B1 (fr) * | 1992-12-11 | 1995-03-10 | Lvmh Rech | Utilisation d'un extrait de Simarouba pour l'atténuation des taches pigmentaires cutanées. |
US5646184A (en) * | 1993-03-25 | 1997-07-08 | Kao Corporation | Preparation for external application to the skin and novel benzoic acid derivatives |
FR2715844B1 (fr) * | 1994-02-04 | 1996-03-29 | Oreal | Emulsion contenant de l'acide ascorbique stabilisé, procédé de traitement cosmétique la mettant en Óoeuvre, ses utilisations. |
IL109012A (en) * | 1994-03-17 | 1998-09-24 | Fischer Pharma Ltd | Skin whitening composition comprising glycyrrhyza glabra and hydroxy acids |
US5874463A (en) * | 1994-10-24 | 1999-02-23 | Ancira; Margaret | Hydroxy-kojic acid skin peel |
FR2732594B1 (fr) * | 1995-04-07 | 1997-06-06 | Oreal | Utilisation de derives d'acide salicylique pour la depigmentation de la peau |
FR2736263B1 (fr) * | 1995-07-07 | 1997-09-26 | C3D Sarl | Composition dermocosmetique depigmentante et son utilisation |
EP0865497B1 (en) * | 1995-12-07 | 2002-09-25 | Zylepsis Limited | Allomelanin production |
FR2754253A1 (fr) * | 1996-10-07 | 1998-04-10 | Roche Posay Lab Pharma | Nouvelle association de derives d'acide salicylique et d'hydroquinone comme inhibiteur de la tyrosinase pour la depigmentation de la peau, et composition la comprenant |
US6982091B2 (en) * | 2001-08-29 | 2006-01-03 | Umd, Inc. | Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy |
EP1260212A1 (de) * | 2001-05-21 | 2002-11-27 | Cognis France S.A. | Kosmetische Mittel |
DE10215055A1 (de) * | 2002-04-03 | 2003-10-30 | Univ Schiller Jena | Verwendung von Kaffeesäureestern zur Herstellung von kosmetischen nutrazeutischen sowie pharmazeutischen Präparaten und Arzneimitteln |
US8343519B2 (en) * | 2003-02-19 | 2013-01-01 | L'oreal S.A. | Chemical enhancer and method |
US7527811B2 (en) * | 2003-12-23 | 2009-05-05 | Clr Chemisches Laboratorium Dr. Kurt Richter Gmbh | Topical depigmenting formulations comprising an extract of Bellis perennis |
TW200534875A (en) * | 2004-04-23 | 2005-11-01 | Lonza Ag | Personal care compositions and concentrates for making the same |
FR2870122A1 (fr) * | 2004-05-14 | 2005-11-18 | Galderma Res & Dev | Composition pharmaceutique ou cosmetique comprenant du mequinol et au moins un agent depigmentant |
JP2008526963A (ja) * | 2005-01-14 | 2008-07-24 | リポ ケミカルズ インコーポレイテッド | 過度に色素沈着した皮膚を処置するための組成物および方法 |
FR2892923B1 (fr) * | 2005-11-08 | 2009-01-16 | Engelhard Lyon Sa | Utilisatiion des derives de l'acide para-coumarique ou para- hydroxycinnamique dans des compositions cosmetiques ou dermatologiques. |
GB2435419B (en) * | 2006-02-21 | 2008-03-05 | Syntopix Ltd | Formulations |
FR2918570B1 (fr) * | 2007-07-09 | 2012-10-05 | Engelhard Lyon | DIGLYCATION DES AGEs. |
EP2340027A4 (en) * | 2008-09-03 | 2012-04-04 | Bionovo Inc | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER |
JP2013530996A (ja) * | 2010-06-30 | 2013-08-01 | ネステク ソシエテ アノニム | 皮膚の色素沈着を調節するための、栄養補助食品におけるカフタル酸及び誘導体の使用 |
RU2012155857A (ru) | 2010-06-30 | 2014-06-27 | Нестек С.А. | Применение цикориевой кислоты и молочнокислых бактерий в биологически активной добавке к пище для регулирования пигментации кожи |
WO2012000959A1 (en) * | 2010-06-30 | 2012-01-05 | Nestec S.A. | Use of caftaric acid and lactic bacterium in food or beverages for regulating skin pigmentation |
WO2012000960A1 (en) * | 2010-06-30 | 2012-01-05 | Nestec S.A. | Use of chicoric acid and derivatives for regulating skin pigmentation |
GB2497985B (en) * | 2011-12-28 | 2014-03-12 | Pangaea Lab Ltd | A composition to stabilise kojic acid |
JP2015140309A (ja) * | 2014-01-28 | 2015-08-03 | 一丸ファルコス株式会社 | カフェ酸又はカフェ酸誘導体を有効成分とするキネシン抑制剤 |
US11123279B2 (en) * | 2016-01-19 | 2021-09-21 | Achromaz Pte. Ltd. | Cosmetic composition and the use thereof for regulating skin quality |
KR102475130B1 (ko) * | 2016-03-31 | 2022-12-07 | (주)아모레퍼시픽 | 펜타사이클릭 트리터펜 카페익 액씨드 에스터를 포함하는 피부 보습 또는 피부 미백용 조성물 |
TWI735652B (zh) * | 2016-09-29 | 2021-08-11 | 心悅生醫股份有限公司 | 麴酸之共晶和/或共熔結晶、包含其之組合物與用途 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1533371A (fr) * | 1967-06-07 | 1968-07-19 | Produits dermo-cosmétiques à base d'extraits de caféier | |
JPS56161315A (en) * | 1980-05-16 | 1981-12-11 | Ichimaru Boeki Kk | Oil-soluble skin anatriptic of ferulic ester |
JPS62120312A (ja) * | 1985-11-19 | 1987-06-01 | Pola Chem Ind Inc | 美肌化粧料 |
FR2613622A1 (fr) * | 1987-04-09 | 1988-10-14 | Cariel Leon | Composition pharmaceutique et/ou cosmetique a activite regulatrice de la pigmentation cutanee |
EP0300842A1 (fr) * | 1987-06-12 | 1989-01-25 | Lvmh Recherche | Composition pharmaceutique ou cosmétique contenant de l'hydroquinone et de l'acide kojique en liposomes |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3982999A (en) * | 1974-07-26 | 1976-09-28 | Kharasch Jerome A | Complexing cresolase with copper chelating agents |
US4136166A (en) * | 1977-04-18 | 1979-01-23 | Helena Rubinstein, Inc. | Skin lightening composition |
NL7804290A (nl) * | 1977-05-12 | 1978-11-14 | Henkel Kgaa | Ontsteking vertragend middel voor cosmetische prepara- ten. |
FR2581542B1 (fr) * | 1985-05-07 | 1988-02-19 | Oreal | Compositions topiques destinees au traitement de la peau a base de derives de l'acide salicylique |
GB8600822D0 (en) * | 1986-01-15 | 1986-02-19 | Unilever Plc | Treatment of skin disorders |
JPH089527B2 (ja) * | 1986-11-27 | 1996-01-31 | 日清製油株式会社 | 抗炎症性化粧料 |
JP2565513B2 (ja) * | 1987-09-25 | 1996-12-18 | 三省製薬株式会社 | メラニン生成抑制外用薬剤 |
JP2658235B2 (ja) * | 1988-08-18 | 1997-09-30 | 石川島播磨重工業株式会社 | 幅圧下プレス装置の幅圧下制御方法 |
JPH02255607A (ja) * | 1989-03-29 | 1990-10-16 | Pias Arise Kk | 色白化粧料 |
-
1989
- 1989-10-20 FR FR8913774A patent/FR2653336B1/fr not_active Expired - Fee Related
-
1990
- 1990-10-18 MX MX022905A patent/MX173203B/es unknown
- 1990-10-19 BR BR909006960A patent/BR9006960A/pt not_active Application Discontinuation
- 1990-10-19 CA CA002044269A patent/CA2044269C/fr not_active Expired - Fee Related
- 1990-10-19 EP EP90916095A patent/EP0450040B1/fr not_active Expired - Lifetime
- 1990-10-19 BE BE9000994A patent/BE1003833A3/fr not_active IP Right Cessation
- 1990-10-19 AT AT90916095T patent/ATE200977T1/de active
- 1990-10-19 AR AR90318119A patent/AR244545A1/es active
- 1990-10-19 ES ES09150019A patent/ES2085192B1/es not_active Expired - Fee Related
- 1990-10-19 WO PCT/FR1990/000760 patent/WO1991005543A1/fr not_active IP Right Cessation
- 1990-10-19 US US07/691,045 patent/US5164185A/en not_active Expired - Fee Related
- 1990-10-19 AU AU66288/90A patent/AU638768B2/en not_active Ceased
- 1990-10-19 IT IT02179590A patent/IT1251741B/it active IP Right Grant
- 1990-10-19 DE DE69033731T patent/DE69033731T2/de not_active Expired - Fee Related
- 1990-10-19 CH CH1910/91A patent/CH682129A5/fr not_active IP Right Cessation
- 1990-10-19 ZA ZA908398A patent/ZA908398B/xx unknown
- 1990-10-19 JP JP2514797A patent/JP2659618B2/ja not_active Expired - Fee Related
-
1991
- 1991-06-19 GB GB9113276A patent/GB2244005B/en not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1533371A (fr) * | 1967-06-07 | 1968-07-19 | Produits dermo-cosmétiques à base d'extraits de caféier | |
JPS56161315A (en) * | 1980-05-16 | 1981-12-11 | Ichimaru Boeki Kk | Oil-soluble skin anatriptic of ferulic ester |
JPS62120312A (ja) * | 1985-11-19 | 1987-06-01 | Pola Chem Ind Inc | 美肌化粧料 |
FR2613622A1 (fr) * | 1987-04-09 | 1988-10-14 | Cariel Leon | Composition pharmaceutique et/ou cosmetique a activite regulatrice de la pigmentation cutanee |
EP0300842A1 (fr) * | 1987-06-12 | 1989-01-25 | Lvmh Recherche | Composition pharmaceutique ou cosmétique contenant de l'hydroquinone et de l'acide kojique en liposomes |
Non-Patent Citations (2)
Title |
---|
BASE DE DATOS WPIL en QUESTEL, semana 8204, Londres: Derwent Publications Ltd., AN-82-06725E & JP 56161315 A (ICHIMARU BOEKI KK) * Resumen * * |
PATENT ABSTRACTS OF JAPAN, Vol. 11, N 349 (C-456), 1987 & JP 62120312 A (POLA CHEM IND INC) * Resumen * * |
Also Published As
Publication number | Publication date |
---|---|
MX173203B (es) | 1994-02-08 |
BE1003833A3 (fr) | 1992-06-23 |
IT9021795A0 (it) | 1990-10-19 |
IT1251741B (it) | 1995-05-23 |
ZA908398B (en) | 1991-08-28 |
BR9006960A (pt) | 1991-11-12 |
CA2044269C (fr) | 1999-01-05 |
EP0450040B1 (fr) | 2001-05-09 |
JP2659618B2 (ja) | 1997-09-30 |
WO1991005543A1 (fr) | 1991-05-02 |
GB2244005A (en) | 1991-11-20 |
FR2653336B1 (fr) | 1994-04-08 |
GB2244005B (en) | 1993-10-13 |
AR244545A1 (es) | 1993-11-30 |
AU638768B2 (en) | 1993-07-08 |
GB9113276D0 (en) | 1991-08-07 |
IT9021795A1 (it) | 1992-04-19 |
DE69033731T2 (de) | 2002-02-07 |
ATE200977T1 (de) | 2001-05-15 |
ES2085192B1 (es) | 1997-02-01 |
US5164185A (en) | 1992-11-17 |
JPH04502476A (ja) | 1992-05-07 |
EP0450040A1 (fr) | 1991-10-09 |
CH682129A5 (es) | 1993-07-30 |
FR2653336A1 (fr) | 1991-04-26 |
DE69033731D1 (de) | 2001-06-13 |
AU6628890A (en) | 1991-05-16 |
CA2044269A1 (fr) | 1991-04-21 |
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