ES2075249T3 - Dispositivo adhesivo para la administracion transdermica de un agente activo. - Google Patents
Dispositivo adhesivo para la administracion transdermica de un agente activo.Info
- Publication number
- ES2075249T3 ES2075249T3 ES91105933T ES91105933T ES2075249T3 ES 2075249 T3 ES2075249 T3 ES 2075249T3 ES 91105933 T ES91105933 T ES 91105933T ES 91105933 T ES91105933 T ES 91105933T ES 2075249 T3 ES2075249 T3 ES 2075249T3
- Authority
- ES
- Spain
- Prior art keywords
- cir
- plaster layer
- ingredient
- active agent
- percutaneous absorption
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN ADHESIVO MEDICO QUE COMPRENDE UNA CAPA DE EMPLASTO QUE CONTIENE LOS SIGUIENTES INGREDIENTES, CARACTERIZADA POR QUE EL INGREDIENTE (2) SE INCORPORA EN CANTIDAD MAYOR QUE EL INGREDIENTE (5) Y EN CANTIDAD NO MENOR DEL 25% DEL PESO RELATIVO A LA CANTIDAD TOTAL DE LOS INGREDIENTES (1)~(5) , Y LA CAPA DE EMPLASTO EN UN TIPO W/O: 1 UN INGREDIENTE MEDICINAL. 2 UN POLIMERO HIDROFOBICO CON UNA TEMPERATURA DE TRANSICION DE CRISTAL (TG) DE 65 C A 35 C, 3 UN AGENTE DE FOMENTO DE ABSORCION PERCUTANEA, 4 AGUA, Y 5 UN POLIMERO HIDROFILICO SOLUBLE O CAPAZ DE CRECER EN AGUA; Y UN ADHESIVO MEDICO QUE CONTIENE UNA CAPA BASE POROSA EN LA CAPA DE EMPLASTO O EN CONTACTO CON LA CAPA DE EMPLASTO, QUE PERMITE LA LIBERACION ESTABLE DEL INGREDIENTE MEDICINAL, DE LOS AGENTES DE FOMENTO DE ABSORCION PERCUTANEA Y QUE MANTIENE LOS EFECTOS FARMACOLOGICOS DURANTE UN LARGO PERIODO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2104294A JP2849937B2 (ja) | 1990-04-18 | 1990-04-18 | 医療用貼付剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2075249T3 true ES2075249T3 (es) | 1995-10-01 |
Family
ID=14376914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91105933T Expired - Lifetime ES2075249T3 (es) | 1990-04-18 | 1991-04-13 | Dispositivo adhesivo para la administracion transdermica de un agente activo. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5176916A (es) |
EP (1) | EP0452837B1 (es) |
JP (1) | JP2849937B2 (es) |
AT (1) | ATE126445T1 (es) |
CA (1) | CA2040698A1 (es) |
DE (1) | DE69112108T2 (es) |
ES (1) | ES2075249T3 (es) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69108512T2 (de) * | 1990-05-17 | 1995-08-03 | Hisamitsu Pharmaceutical Co | Estradiol enthaltende transdermale zubereitung. |
US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US6197325B1 (en) | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US6117425A (en) * | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
JP3523275B2 (ja) * | 1992-03-26 | 2004-04-26 | 東光薬品工業株式会社 | 貼付剤 |
WO1993023019A1 (en) * | 1992-05-11 | 1993-11-25 | Sri International | Transdermal drug delivery systems and related compositions and methods of use |
US6162456A (en) * | 1992-09-24 | 2000-12-19 | Ortho-Mcneil Pharmaceutical, Inc. | Adhesive transdermal drug delivery matrix of a physical blend of hydrophilic and hydrophobic polymers |
US5989586A (en) * | 1992-10-05 | 1999-11-23 | Cygnus, Inc. | Two-phase matrix for sustained release drug delivery device |
GB2273044B (en) * | 1992-12-02 | 1997-04-09 | Pacific Chem Co Ltd | Medicinal patches for percutaneous administration |
US5613958A (en) * | 1993-05-12 | 1997-03-25 | Pp Holdings Inc. | Transdermal delivery systems for the modulated administration of drugs |
JPH08512054A (ja) † | 1993-06-25 | 1996-12-17 | アルザ・コーポレーション | 経皮系におけるポリ−n−ビニルアミドの含有 |
DE4337945A1 (de) * | 1993-11-06 | 1995-05-11 | Labtec Gmbh | Pflaster zur Behandlung von Nagelmykosen |
JP2753800B2 (ja) * | 1994-04-14 | 1998-05-20 | 日東電工株式会社 | 経皮吸収型製剤 |
US5552153A (en) * | 1994-04-28 | 1996-09-03 | Hoffman-La Roche Inc. | Pharmaceutical composition for transdermal delivery |
US5580574A (en) * | 1994-04-28 | 1996-12-03 | Hoffmann-La Roche Inc. | Pharmaceutical composition for transdermal delivery |
US5795916A (en) * | 1994-08-09 | 1998-08-18 | Tsumura & Co. | Composition of external preparation |
JP4102901B2 (ja) * | 1994-09-14 | 2008-06-18 | スリーエム カンパニー | 経皮薬剤導入用マトリックス |
DE69535737T2 (de) * | 1994-09-16 | 2009-04-09 | Hisamitsu Pharmaceutical Co., Inc., Tosu-shi | Pflaster zur externen anwendung |
MX9702750A (es) | 1994-10-28 | 1997-09-30 | Kimberly Clark Wordlwide Inc | Articulo absorbente autoadherente. |
JP3908795B2 (ja) * | 1994-11-29 | 2007-04-25 | 久光製薬株式会社 | ケトチフェン含有経皮投与製剤 |
US5686083A (en) * | 1994-12-08 | 1997-11-11 | Schering-Plough Healthcare Products Inc. | Compositions for treating corns and calluses |
US5573778A (en) * | 1995-03-17 | 1996-11-12 | Adhesives Research, Inc. | Drug flux enhancer-tolerant pressure sensitive adhesive composition |
DE19512181C2 (de) | 1995-03-31 | 2003-11-06 | Hexal Pharma Gmbh | Transdermales System mit Ramipril und/oder Trandolapril als ACE-Hemmer |
US5780050A (en) * | 1995-07-20 | 1998-07-14 | Theratech, Inc. | Drug delivery compositions for improved stability of steroids |
FR2739031B1 (fr) * | 1995-09-27 | 1997-11-21 | Lhd Lab Hygiene Dietetique | Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique |
US5755758A (en) * | 1995-11-07 | 1998-05-26 | Medtronic, Inc. | Intramuscular stimulation lead with enhanced infection resistance |
TW411277B (en) * | 1996-05-13 | 2000-11-11 | Hisamitsu Pharmaceutical Co | Percutaneous tape preparation containing fentanyl |
US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
DK48997A (da) * | 1997-04-30 | 1999-01-05 | Coloplast As | Klæbemiddel samt anvendelse af dette middel |
US7150881B2 (en) * | 1997-06-26 | 2006-12-19 | Mylan Technologies, Inc. | Adhesive mixture for transdermal delivery of highly plasticizing drugs |
JP4138910B2 (ja) * | 1997-07-02 | 2008-08-27 | 帝國製薬株式会社 | 経皮吸収性が良好で且つ皮膚刺激性の少ない塩酸アゼラスチン含有経皮製剤 |
EP0891782B1 (en) * | 1997-07-17 | 2005-05-25 | Nitto Denko Corporation | Medical adhesive sheet and production thereof |
KR19990026792A (ko) * | 1997-09-26 | 1999-04-15 | 김윤 | 디클로페낙 디에틸암모늄염을 함유한 매트릭스형 패취제제 |
AU1728099A (en) | 1997-12-22 | 1999-07-12 | Alza Corporation | Monoglyceride and ethyl palmitate permeation enhancer compositions |
DE19800277B4 (de) * | 1998-01-07 | 2004-09-02 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur Rückgewinnung von Arzneistoffen aus Zubereitungen, deren Vorprodukten oder Abfällen |
US6146656A (en) * | 1998-01-22 | 2000-11-14 | Nitto Denko Corporation | Percutaneous absorption preparation |
US6193996B1 (en) * | 1998-04-02 | 2001-02-27 | 3M Innovative Properties Company | Device for the transdermal delivery of diclofenac |
IT1309588B1 (it) * | 1999-03-05 | 2002-01-24 | Altergon Sa | Cerotto con spessore sottile contenente betametasone ed acidoialuronico per il trattamento di psoriasi, dermatite, dermatosi. |
IT1312088B1 (it) * | 1999-04-21 | 2002-04-04 | Altergon Sa | Cerotto per uso topico contenente eparina e diclofenac. |
DE19918105C1 (de) * | 1999-04-22 | 2000-09-21 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit einem stark wirksamen Neuroleptikum |
US7063859B1 (en) | 1999-04-28 | 2006-06-20 | Noven Pharmaceuticals, Inc. | Barrier film lined backing layer composition and method for topical administration of active agents |
WO2000076485A1 (fr) * | 1999-06-11 | 2000-12-21 | Lintec Corporation | Preparation sensible a l'humidite du type a absorption percutanee |
DK1197209T3 (da) * | 1999-07-15 | 2011-04-04 | Hisamitsu Pharmaceutical Co | Perkutant absorberbare præparater |
US20020054895A1 (en) * | 1999-07-23 | 2002-05-09 | Alwyn Company, Inc. | Allantoin-containing skin cream |
US6864274B2 (en) * | 1999-07-23 | 2005-03-08 | Alwyn Company, Inc. | Allantoin-containing skin cream |
US6896897B2 (en) * | 1999-07-23 | 2005-05-24 | Alwyn Company, Inc. | Flexible applicator for applying oil-in-water emulsion with improved stability |
US6673826B2 (en) | 1999-07-23 | 2004-01-06 | Alwyn Company, Inc. | Methods for treatment of inflammatory diseases |
US20020055531A1 (en) * | 1999-07-23 | 2002-05-09 | Elliott Farber | Methods for treatment of inflammatory diseases |
JP4659943B2 (ja) * | 2000-02-25 | 2011-03-30 | 帝三製薬株式会社 | 塩酸ブプレノルフィン含有貼付剤 |
DE10033855A1 (de) * | 2000-07-12 | 2002-01-31 | Hexal Ag | Matrixkontrolliertes transdermales System mit Sulfonsäuresalz eines ACE-Hemmers |
AU2001293559A1 (en) * | 2000-09-19 | 2002-04-02 | Dermal Therapy (Barbados) Inc. | Topical analgesic compositions containing aliphatic polyamines and methods of using same |
US6648911B1 (en) | 2000-11-20 | 2003-11-18 | Avantec Vascular Corporation | Method and device for the treatment of vulnerable tissue site |
ATE464887T1 (de) * | 2001-05-31 | 2010-05-15 | Hisamitsu Pharmaceutical Co | Perkutan resorbierbare pflaster |
WO2005021058A2 (en) | 2003-09-02 | 2005-03-10 | Coloplast A/S | Adhesive composition comprising hydrophilic and hydrophobic silicone elastomers |
JP4268527B2 (ja) * | 2004-01-16 | 2009-05-27 | 積水化学工業株式会社 | 外用治療シート |
WO2006082728A1 (ja) * | 2005-02-04 | 2006-08-10 | Hisamitsu Pharmaceutical Co., Inc. | 経皮吸収貼付剤 |
DE102005058166A1 (de) | 2005-12-05 | 2007-06-06 | Hexal Ag | Matrixkontrolliertes transdermales System mit Amin-Salzen der ACE-Hemmer-Dicarbonsäuren |
US20090017120A1 (en) * | 2007-03-23 | 2009-01-15 | Humco Holding Group, Inc. | Phase stable lecithin organogel composition |
US8182647B2 (en) * | 2007-07-23 | 2012-05-22 | Cohera Medical, Inc. | Hydrophilic biodegradable adhesives |
CN102781473B (zh) * | 2009-11-12 | 2016-02-17 | 学校法人日本大学 | 外用药物组合物 |
US20140135372A1 (en) | 2010-02-02 | 2014-05-15 | Elliott Farber | Compositions and methods of treatment of inflammatory skin conditions using allantoin |
JP5820469B2 (ja) | 2010-04-30 | 2015-11-24 | テイコク ファーマ ユーエスエー インコーポレーテッド | プロピニルアミノインダンの経皮組成物 |
CN103476404B (zh) | 2011-03-24 | 2017-09-29 | 帝国制药美国公司 | 包含活性剂层和活性剂转化层的透皮组合物 |
FR2975002B1 (fr) * | 2011-05-12 | 2020-08-14 | Jean-Noel Thorel | Procede de traitement cosmetique de la peau en deux etapes successives |
US9913812B2 (en) | 2011-11-09 | 2018-03-13 | Teikoku Pharma Usa, Inc. | Methods for the treatment of skin neoplasms |
CA2887705C (en) | 2012-11-02 | 2018-07-24 | Teikoku Pharma Usa, Inc. | Propynylaminoindan transdermal compositions |
EP3037088B1 (en) * | 2013-08-23 | 2018-11-21 | Hisamitsu Pharmaceutical Co., Inc. | Cataplasm and method for producing same |
JP6188933B2 (ja) | 2013-10-07 | 2017-08-30 | テイコク ファーマ ユーエスエー インコーポレーテッド | 非鎮静量のデクスメデトミジンの経皮送達用方法及び組成物 |
TWI704933B (zh) | 2013-10-07 | 2020-09-21 | 美商帝國製藥美國股份有限公司 | 右美托咪啶經皮輸送裝置及使用其之方法 |
CN106456561B (zh) | 2013-10-07 | 2020-02-28 | 帝国制药美国公司 | 使用右旋美托咪啶经皮组合物治疗注意力缺陷多动症、焦虑症和失眠症的方法和组合物 |
TW201609200A (zh) | 2013-12-18 | 2016-03-16 | 丸石製藥股份有限公司 | 含水型貼劑 |
KR102094586B1 (ko) | 2014-12-22 | 2020-03-27 | 히사미쓰 세이야꾸 가부시키가이샤 | 파프제 |
JP6632810B2 (ja) * | 2015-03-31 | 2020-01-22 | 小林製薬株式会社 | 外用医薬組成物 |
CN110090206A (zh) * | 2018-01-30 | 2019-08-06 | 日东电工株式会社 | 经皮吸收型制剂 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2045618B (en) * | 1979-04-03 | 1983-05-11 | Hisamitsu Pharmaceutical Co | Adhesive plaster |
JPH0614957B2 (ja) * | 1983-06-20 | 1994-03-02 | 帝国製薬株式会社 | テ−プ状含水貼付剤及びその製造方法 |
JPS6124517A (ja) * | 1984-07-11 | 1986-02-03 | Nichiban Co Ltd | 循環器疾患用貼布治療製剤 |
JPS61221121A (ja) * | 1985-03-27 | 1986-10-01 | Nitto Electric Ind Co Ltd | テ−プ製剤 |
JPS61280426A (ja) * | 1985-06-04 | 1986-12-11 | Ikeda Mohandou:Kk | 消炎鎮痛用貼付剤 |
US4732808A (en) * | 1985-11-14 | 1988-03-22 | Minnesota Mining And Manufacturing Company | Macromer reinforced pressure sensitive skin adhesive sheet material |
US4983396A (en) * | 1985-12-06 | 1991-01-08 | Key Pharmaceuticals, Inc. | Percutaneous penetration enhancer of oleic acid and 2-ethyl-1,3-hexanediol |
WO1988001170A1 (en) * | 1986-08-20 | 1988-02-25 | Teikoku Seiyaku Co., Ltd. | Steroidal drug-containing preparation for external use |
US4855142A (en) * | 1987-02-27 | 1989-08-08 | Ciba-Geigy Corporation | Pharmaceutical plaster |
CH674618A5 (es) * | 1987-04-02 | 1990-06-29 | Ciba Geigy Ag | |
IL86170A (en) * | 1987-05-01 | 1992-12-01 | Elan Transdermal Ltd | Preparations and compositions comprising nicotine for percutaneous administration |
DE3823070A1 (de) * | 1988-07-07 | 1990-02-22 | Kettelhack Riker Pharma Gmbh | Selbstklebendes heftpflaster |
EP0359004A1 (en) * | 1988-09-05 | 1990-03-21 | Takeda Chemical Industries, Ltd. | Transdermal therapeutic composition for the treatment of hypertension |
-
1990
- 1990-04-18 JP JP2104294A patent/JP2849937B2/ja not_active Expired - Lifetime
-
1991
- 1991-04-13 AT AT91105933T patent/ATE126445T1/de not_active IP Right Cessation
- 1991-04-13 EP EP91105933A patent/EP0452837B1/en not_active Expired - Lifetime
- 1991-04-13 ES ES91105933T patent/ES2075249T3/es not_active Expired - Lifetime
- 1991-04-13 DE DE69112108T patent/DE69112108T2/de not_active Expired - Fee Related
- 1991-04-17 CA CA002040698A patent/CA2040698A1/en not_active Abandoned
- 1991-04-17 US US07/686,383 patent/US5176916A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2040698A1 (en) | 1991-10-19 |
US5176916A (en) | 1993-01-05 |
JP2849937B2 (ja) | 1999-01-27 |
EP0452837A3 (en) | 1992-03-04 |
DE69112108D1 (de) | 1995-09-21 |
EP0452837B1 (en) | 1995-08-16 |
ATE126445T1 (de) | 1995-09-15 |
EP0452837A2 (en) | 1991-10-23 |
JPH041127A (ja) | 1992-01-06 |
DE69112108T2 (de) | 1996-01-11 |
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Legal Events
Date | Code | Title | Description |
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FG2A | Definitive protection |
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