ES2059550T3 - Derivados de la bencimidazola, su preparacion y su aplicacion en terapeutica. - Google Patents

Derivados de la bencimidazola, su preparacion y su aplicacion en terapeutica.

Info

Publication number
ES2059550T3
ES2059550T3 ES88401866T ES88401866T ES2059550T3 ES 2059550 T3 ES2059550 T3 ES 2059550T3 ES 88401866 T ES88401866 T ES 88401866T ES 88401866 T ES88401866 T ES 88401866T ES 2059550 T3 ES2059550 T3 ES 2059550T3
Authority
ES
Spain
Prior art keywords
radical
hydrogen
therapeutics
application
bencimidazola
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88401866T
Other languages
English (en)
Inventor
Philippe Manoury
Guy Rossey
Jean Binet
Gerard Defosse
Najib Jabri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of ES2059550T3 publication Critical patent/ES2059550T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

DERIVADOS DE BENCIMIDAZOL QUE CORRESPONDEN A LA FORMULA(I) EN LA QUE R1 ES UN ATOMO DE HIDROGENO O EL RADICAL METILO, R2 ES UN ATOMPO DE HIDROGENO, EL RADICAL METILO O EL RADICAL ACETILO, R3 ES UN ATOMO DE HIDROGENO, EL RADICAL METILO O EL RADICAL ACETILO, R4 ES UN ATOMO DE HIDROGENO O DE HALOGENO, ASI COMO SUS SALES DE ADICION A ACIDOS FARMACEUTICAMENTE ACEPTABLES, Y LAS FORMAS TANTOMERAS DE LOS COMPUESTOS. APLICACION EN TERAPEUTICA.
ES88401866T 1987-07-23 1988-07-20 Derivados de la bencimidazola, su preparacion y su aplicacion en terapeutica. Expired - Lifetime ES2059550T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8710409A FR2618435B1 (fr) 1987-07-23 1987-07-23 Derives de benzimidazole, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES2059550T3 true ES2059550T3 (es) 1994-11-16

Family

ID=9353449

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88401866T Expired - Lifetime ES2059550T3 (es) 1987-07-23 1988-07-20 Derivados de la bencimidazola, su preparacion y su aplicacion en terapeutica.

Country Status (19)

Country Link
US (1) US4857536A (es)
EP (1) EP0304353B1 (es)
JP (1) JP2690749B2 (es)
KR (1) KR890002111A (es)
AT (1) ATE94164T1 (es)
AU (1) AU602418B2 (es)
CA (1) CA1310010C (es)
DE (1) DE3883891T2 (es)
DK (1) DK413188A (es)
ES (1) ES2059550T3 (es)
FI (1) FI883484A7 (es)
FR (1) FR2618435B1 (es)
HU (1) HUT47266A (es)
IE (1) IE61824B1 (es)
IL (1) IL87174A (es)
NO (1) NO883263L (es)
NZ (1) NZ225528A (es)
PT (1) PT88089B (es)
ZA (1) ZA885367B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658823B1 (fr) * 1990-02-27 1992-04-30 Adir Nouveaux derives d'aminomethylpiperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent .
EP0561973A1 (en) * 1990-12-14 1993-09-29 Merrell Dow Pharmaceuticals Inc. Antiallergic compounds
FR2674853B1 (fr) * 1991-04-03 1995-01-20 Synthelabo Derives de piperidinylguanidine, leur preparation et leur application en therapeutique.
US5223704A (en) * 1992-03-31 1993-06-29 At&T Bell Laboratories Planar buried quantum well photodetector
FR2693194B1 (fr) * 1992-07-03 1994-09-23 Synthelabo Dérivés d'alcanecarboxamide, leur préparation et leur application thérapeutique.
FR2696176B1 (fr) * 1992-09-28 1994-11-10 Synthelabo Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
JP7450534B2 (ja) 2017-10-19 2024-03-15 帝人ファーマ株式会社 ベンズイミダゾール誘導体及びその用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3528991A (en) * 1964-02-19 1970-09-15 Sterling Drug Inc 1h- and 2h-benzotriazolyl-lower-alkyl-amidoximes,-amidines,and -guanidines
CA1140119A (en) * 1978-04-03 1983-01-25 Joseph Torremans N-heterocyclyl-4-piperidinamines
US4347856A (en) * 1980-05-20 1982-09-07 United States Tobacco Company Method and apparatus for removing cigar wrappers from the web of a bobbin
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
FR2587029B1 (fr) * 1985-09-11 1987-10-30 Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
KR890002111A (ko) 1989-04-08
FI883484L (fi) 1989-01-24
PT88089A (pt) 1989-06-30
IE882257L (en) 1989-01-23
NO883263D0 (no) 1988-07-22
CA1310010C (en) 1992-11-10
PT88089B (pt) 1995-03-01
US4857536A (en) 1989-08-15
ZA885367B (en) 1989-06-28
AU1971688A (en) 1989-01-27
EP0304353A1 (fr) 1989-02-22
FR2618435A1 (fr) 1989-01-27
DK413188D0 (da) 1988-07-22
NZ225528A (en) 1990-05-28
IL87174A0 (en) 1988-12-30
FI883484A0 (fi) 1988-07-22
EP0304353B1 (fr) 1993-09-08
FI883484A7 (fi) 1989-01-24
DE3883891T2 (de) 1994-04-14
HUT47266A (en) 1989-02-28
JP2690749B2 (ja) 1997-12-17
AU602418B2 (en) 1990-10-11
DK413188A (da) 1989-01-24
ATE94164T1 (de) 1993-09-15
IL87174A (en) 1993-02-21
FR2618435B1 (fr) 1989-10-27
DE3883891D1 (de) 1993-10-14
IE61824B1 (en) 1994-11-30
JPS6434978A (en) 1989-02-06
NO883263L (no) 1989-01-24

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