ES2062443T3 - Nuevos derivados peptidicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. - Google Patents
Nuevos derivados peptidicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.Info
- Publication number
- ES2062443T3 ES2062443T3 ES90401877T ES90401877T ES2062443T3 ES 2062443 T3 ES2062443 T3 ES 2062443T3 ES 90401877 T ES90401877 T ES 90401877T ES 90401877 T ES90401877 T ES 90401877T ES 2062443 T3 ES2062443 T3 ES 2062443T3
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- preparation procedure
- denotes
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LA INVENCION SE REFIERE A DERIVADOS DE FORMULA GENERAL (I), EN LA QUE A REPRESENTA CON LOS ATOMOS DE CARBONO Y DE NITROGENO CON LOS QUE ESTA UNIDO UN GRUPO CICLOAMIDICO; B REPRESENTA CON LOS ATOMOS DE CARBONO Y DE NITROGENO CON LOS QUE ESTA UNIDO UNA ESTRUCTURA POLICICLICA SATURADA; R REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO INFERIOR, UN GRUPO IMIDAZOLIL-4 METILO SUSTITUIDO O NO; SUS DIASTEREOISOMEROS, ENANTIOMEROS Y EPIMEROS, ASI COMO SUS SALES DE ADICION A UN ACIDO FARMACEUTICAMENTE ACEPTABLE. MEDICAMENTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR898908672A FR2649110B1 (fr) | 1989-06-29 | 1989-06-29 | Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2062443T3 true ES2062443T3 (es) | 1994-12-16 |
Family
ID=9383248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90401877T Expired - Lifetime ES2062443T3 (es) | 1989-06-29 | 1990-06-29 | Nuevos derivados peptidicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. |
Country Status (15)
Country | Link |
---|---|
US (1) | US5098888A (es) |
EP (1) | EP0406119B1 (es) |
JP (1) | JPH0348695A (es) |
AT (1) | ATE100464T1 (es) |
AU (1) | AU627898B2 (es) |
CA (1) | CA2019633A1 (es) |
DE (1) | DE69006116T2 (es) |
DK (1) | DK0406119T3 (es) |
ES (1) | ES2062443T3 (es) |
FR (1) | FR2649110B1 (es) |
IE (1) | IE65156B1 (es) |
NZ (1) | NZ233908A (es) |
OA (1) | OA09454A (es) |
PT (1) | PT94537A (es) |
ZA (1) | ZA904495B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2663336B1 (fr) * | 1990-06-18 | 1992-09-04 | Adir | Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US5388555A (en) * | 1992-04-03 | 1995-02-14 | Honda Giken Kogyo Kabushiki Kaisha | Outboard engine assembly |
FR2694295B1 (fr) * | 1992-07-28 | 1994-09-02 | Adir | Nouveaux peptides dérivés de trifluoromethylcetones, leur procéde de préparation et les compositions pharmaceutiques qui les contiennent. |
US5962664A (en) * | 1993-05-13 | 1999-10-05 | Friedhoff; Arnold J. | Psychosis protecting nucleic acid, peptides, compositions and method of use |
FR2710066B1 (fr) * | 1993-09-14 | 1995-10-20 | Synthelabo | Dérivés de 1-[2-amino-5-[1-(triphénylméthyl-1H-imidazol-4-yl]-1-oxopentyl]piperidine, leur préparation et leur utilisation comme intermédiaires de synthèse. |
EP0912602A4 (en) * | 1996-02-05 | 2002-09-11 | Lilly Co Eli | METHOD FOR TREATING COMPLAINTS CAUSED BY BETA AMYLOID PEPTIDES BY TRH |
US5834458A (en) * | 1996-10-09 | 1998-11-10 | Eli Lilly And Company | Heterocyclic compounds and their use |
KR100373825B1 (ko) * | 2000-02-29 | 2003-02-26 | (주)일산금속 | 자전거의 완충장치 |
US20040077605A1 (en) * | 2001-06-20 | 2004-04-22 | Salvati Mark E. | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
AU8821301A (en) | 2000-06-28 | 2002-01-08 | Bristol Myers Squibb Co | Selective androgen receptor modulators and methods for their identification, design and use |
US20030114420A1 (en) * | 2000-06-28 | 2003-06-19 | Salvati Mark E. | Fused cyclic modulators of nuclear hormone receptor function |
US7001911B2 (en) * | 2000-06-28 | 2006-02-21 | Bristol-Myers Squibb Company | Fused cyclic modulators of nuclear hormone receptor function |
EP1854798A3 (en) * | 2000-09-19 | 2007-11-28 | Bristol-Myers Squibb Company | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
US6953679B2 (en) | 2000-09-19 | 2005-10-11 | Bristol-Myers Squibb Company | Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof |
US20040087548A1 (en) | 2001-02-27 | 2004-05-06 | Salvati Mark E. | Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
ATE404544T1 (de) * | 2001-12-19 | 2008-08-15 | Bristol Myers Squibb Co | Kondensierte heterocyclische verbindungen und deren analoga; modulatoren der funktion von nukleären hormonrezeptoren |
BRPI0510305A (pt) * | 2004-04-30 | 2007-10-02 | Takeda Pharmaceutical | composto ou um sal do mesmo, pródroga ou um sal da mesma, agente farmacêutico, método de produção do composto ou um sal do mesmo, inibidor de metaloproteinase de matriz ou um sal do mesmo ou uma pródroga do mesmo, método de inibir uma metaloproteinase de matriz, e, uso de um composto ou de um sal do mesmo ou de uma pródroga do mesmo |
CN102432616B (zh) * | 2011-11-23 | 2014-12-17 | 河北博伦特药业有限公司 | 一种制备l-脯氨酰胺及其中间体的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1523598A (en) * | 1975-03-08 | 1978-09-06 | Reckitt & Colmann Prod Ltd | Tripeptides |
HU180926B (en) * | 1979-06-28 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem |
FR2575753B1 (fr) * | 1985-01-07 | 1987-02-20 | Adir | Nouveaux derives peptidiques a structure polycyclique azotee, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
IT1184164B (it) * | 1985-03-19 | 1987-10-22 | Eniricerche Spa | Triptidi ad azione ipotensiva e procedimento per la loro sintesi |
FR2585709B1 (fr) * | 1985-08-05 | 1987-10-02 | Adir | Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
AU595309B2 (en) * | 1986-05-09 | 1990-03-29 | Dainippon Pharmaceutical Co. Ltd. | Tripeptide derivatives |
US4814342A (en) * | 1986-10-31 | 1989-03-21 | Pfizer Inc. | Nor-statine and nor-cyclostatine polypeptides |
US4956344A (en) * | 1987-09-17 | 1990-09-11 | Hafslund Nycomed A/S | Method for treatment of lesions in the large intestinal epithelium with a tripeptide |
-
1989
- 1989-06-29 FR FR898908672A patent/FR2649110B1/fr not_active Expired - Fee Related
-
1990
- 1990-06-01 NZ NZ233908A patent/NZ233908A/en unknown
- 1990-06-11 US US07/536,193 patent/US5098888A/en not_active Expired - Fee Related
- 1990-06-11 ZA ZA904495A patent/ZA904495B/xx unknown
- 1990-06-12 IE IE210390A patent/IE65156B1/en not_active IP Right Cessation
- 1990-06-22 CA CA002019633A patent/CA2019633A1/fr not_active Abandoned
- 1990-06-28 JP JP2168632A patent/JPH0348695A/ja active Pending
- 1990-06-28 AU AU57911/90A patent/AU627898B2/en not_active Ceased
- 1990-06-28 PT PT94537A patent/PT94537A/pt not_active Application Discontinuation
- 1990-06-28 OA OA59814A patent/OA09454A/xx unknown
- 1990-06-29 EP EP90401877A patent/EP0406119B1/fr not_active Expired - Lifetime
- 1990-06-29 AT AT90401877T patent/ATE100464T1/de not_active IP Right Cessation
- 1990-06-29 ES ES90401877T patent/ES2062443T3/es not_active Expired - Lifetime
- 1990-06-29 DK DK90401877.7T patent/DK0406119T3/da active
- 1990-06-29 DE DE69006116T patent/DE69006116T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE100464T1 (de) | 1994-02-15 |
EP0406119A1 (fr) | 1991-01-02 |
EP0406119B1 (fr) | 1994-01-19 |
AU5791190A (en) | 1991-01-03 |
DE69006116T2 (de) | 1994-07-28 |
JPH0348695A (ja) | 1991-03-01 |
IE902103L (en) | 1990-12-29 |
ZA904495B (en) | 1991-03-27 |
DE69006116D1 (de) | 1994-03-03 |
AU627898B2 (en) | 1992-09-03 |
NZ233908A (en) | 1992-06-25 |
US5098888A (en) | 1992-03-24 |
IE902103A1 (en) | 1991-01-02 |
CA2019633A1 (fr) | 1990-12-29 |
IE65156B1 (en) | 1995-10-04 |
DK0406119T3 (da) | 1994-03-21 |
FR2649110A1 (fr) | 1991-01-04 |
OA09454A (fr) | 1992-10-15 |
FR2649110B1 (fr) | 1994-10-21 |
PT94537A (pt) | 1991-02-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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