ES2123652T3 - 7-(2-aminoetil)-benzotiazolonas. - Google Patents

7-(2-aminoetil)-benzotiazolonas.

Info

Publication number
ES2123652T3
ES2123652T3 ES93913203T ES93913203T ES2123652T3 ES 2123652 T3 ES2123652 T3 ES 2123652T3 ES 93913203 T ES93913203 T ES 93913203T ES 93913203 T ES93913203 T ES 93913203T ES 2123652 T3 ES2123652 T3 ES 2123652T3
Authority
ES
Spain
Prior art keywords
independently represent
benzotiazolonas
aminoetil
independently
fenil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93913203T
Other languages
English (en)
Inventor
Roger Victor Bonnert
Roger Charles Brown
David Ranulf Cheshire
Francis Ince
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Pharmaceuticals Ltd
Astra USA Inc
Original Assignee
Astra Pharmaceuticals Ltd
Astra Pharmaceutical Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharmaceuticals Ltd, Astra Pharmaceutical Products Inc filed Critical Astra Pharmaceuticals Ltd
Application granted granted Critical
Publication of ES2123652T3 publication Critical patent/ES2123652T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Cosmetics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Adhesives Or Adhesive Processes (AREA)

Abstract

SE DESCRIBEN COMPUESTOS DE FORMULA (I), DONDE X E Y INDEPENDIENTEMENTE REPRESENTAN -S(O)N 2, P, Q Y R INDEPENDIENTEMENTE REPRESENTAN 2 O 3, Z REPRESENTA FENIL OPCIONALMENTE SUSTITUIDO POR HALOGENO, -OR1, -NO2 O -NR2R3; O UN N, Q O S DE 5 O 6 MIEMBROS, CONTENIENDO HETEROCICLO, Y R1, R2 Y R3 INDEPENDIENTEMENTE REPRESENTAN HIDROGENO O ALQUILO C1-6, Y DERIVADOS FARMACEUTICAMENTE ACEPTABLES DE LOS MISMOS. TAMBIEN SE DESCRIBEN PROCESOS PARA SU PRODUCCION Y COMPOSICIONES FARMACEUTICAS Y METODOS DE TRATAMIENTO QUE IMPLIQUEN SU USO.
ES93913203T 1992-05-27 1993-05-27 7-(2-aminoetil)-benzotiazolonas. Expired - Lifetime ES2123652T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929211172A GB9211172D0 (en) 1992-05-27 1992-05-27 Compounds

Publications (1)

Publication Number Publication Date
ES2123652T3 true ES2123652T3 (es) 1999-01-16

Family

ID=10716059

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93913203T Expired - Lifetime ES2123652T3 (es) 1992-05-27 1993-05-27 7-(2-aminoetil)-benzotiazolonas.

Country Status (31)

Country Link
EP (1) EP0649418B1 (es)
JP (1) JP3094452B2 (es)
KR (1) KR100279132B1 (es)
CN (1) CN1036393C (es)
AT (1) ATE172726T1 (es)
AU (1) AU675649B2 (es)
CA (1) CA2136553C (es)
CZ (1) CZ286905B6 (es)
DE (1) DE69321835T2 (es)
DK (1) DK0649418T3 (es)
DZ (1) DZ1694A1 (es)
ES (1) ES2123652T3 (es)
FI (1) FI945538A7 (es)
GB (1) GB9211172D0 (es)
HU (2) HUT71124A (es)
IL (1) IL105801A (es)
LV (1) LV12443B (es)
MA (1) MA22895A1 (es)
MX (1) MX9303145A (es)
MY (1) MY131193A (es)
NO (1) NO304739B1 (es)
NZ (1) NZ253190A (es)
PH (1) PH31453A (es)
PL (2) PL172807B1 (es)
RU (1) RU2114108C1 (es)
SG (1) SG48068A1 (es)
SK (1) SK281282B6 (es)
TW (1) TW368501B (es)
UA (1) UA27901C2 (es)
WO (1) WO1993024473A1 (es)
ZA (1) ZA933648B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW356468B (en) * 1995-09-15 1999-04-21 Astra Pharma Prod Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same
GB9526511D0 (en) * 1995-12-23 1996-02-28 Astra Pharma Prod Pharmaceutically active compounds
SE9900693D0 (sv) * 1999-02-26 1999-02-26 Astra Pharma Prod Novel process
SE9902936D0 (sv) * 1999-08-18 1999-08-18 Astra Pharma Prod Pharmaceutical compositions
SE9902937D0 (sv) * 1999-08-18 1999-08-18 Astra Pharma Prod Pharmaceutical compositions
SE9902935D0 (sv) * 1999-08-18 1999-08-18 Astra Pharma Prod Pharmaceutical compositions
SE9902938D0 (sv) * 1999-08-18 1999-08-18 Astra Pharma Prod Pharmaceutical compositions
DE10063957A1 (de) * 2000-12-20 2002-06-27 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Dopamin-Agonisten
GB0218629D0 (en) * 2002-08-09 2002-09-18 Novartis Ag Organic compounds
PE20050130A1 (es) * 2002-08-09 2005-03-29 Novartis Ag Compuestos organicos
JP4851937B2 (ja) 2003-11-21 2012-01-11 セラヴァンス， インコーポレーテッド β２アドレナリン作動性受容体作動薬活性およびムスカリン受容体拮抗薬活性を有する化合物
RU2281769C2 (ru) * 2004-07-16 2006-08-20 Федеральное государственное научное учреждение Всероссийский научно-исследовательский ветеринарный институт Средство для лечения дерматомикозов
GB0426164D0 (en) * 2004-11-29 2004-12-29 Novartis Ag Organic compounds
RU2288715C2 (ru) * 2005-01-11 2006-12-10 ГОУ ВПО "Воронежская государственная медицинская академия им. Н.Н. Бурденко Министерства здравоохранения Российской Федерации" Способ лечения бронхиальной астмы
RU2415136C2 (ru) * 2005-08-09 2011-03-27 Астразенека Аб Новые производные бензотиазолона
TW200738658A (en) 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
TW200738659A (en) * 2005-08-29 2007-10-16 Astrazeneca Ab Novel compounds
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
TW200833670A (en) 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
RU2455295C2 (ru) * 2006-12-20 2012-07-10 АстраЗенека AБ 4-ГИДРОКСИ-2-ОКСО-2,3-ДИГИДРО-1,3-БЕНЗОТИАЗОЛ-7-ИЛЬНЫЕ СОЕДИНЕНИЯ ДЛЯ МОДУЛЯЦИИ β2-АДРЕНОРЕЦЕПТОРНОЙ АКТИВНОСТИ
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
GB0704000D0 (en) * 2007-03-01 2007-04-11 Astrazeneca Ab Salts 670
UY31905A (es) 2008-06-18 2010-01-29 Astrazeneca Ab Derivados de benzoxazinona, procesos de preparación, composiciones farmacéuticas conteniéndolos y aplicaciones.
CN102977050B (zh) * 2012-11-20 2015-04-22 浙江工业大学 一种2-苯并噻唑二甲缩醛和2-苯并噻唑甲醛的合成方法
CN106748930B (zh) * 2016-12-05 2019-03-15 三门峡奥科化工有限公司 3-巯基-1-丙醇的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554284A (en) * 1984-09-12 1985-11-19 Smithkline Beckman Corporation 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones
IE914003A1 (en) * 1990-11-20 1992-05-20 Astra Pharma Prod Biologically Active Amines

Also Published As

Publication number Publication date
NO944509L (no) 1994-11-24
MX9303145A (es) 1994-06-30
FI945538L (fi) 1994-11-25
ATE172726T1 (de) 1998-11-15
IL105801A (en) 1997-01-10
MY131193A (en) 2007-07-31
JP3094452B2 (ja) 2000-10-03
SK143394A3 (en) 1995-06-07
DE69321835T2 (de) 1999-05-12
CN1085899A (zh) 1994-04-27
PL172807B1 (pl) 1997-11-28
WO1993024473A1 (en) 1993-12-09
RU2114108C1 (ru) 1998-06-27
DE69321835D1 (de) 1998-12-03
HUT71124A (en) 1995-11-28
RU94046093A (ru) 1996-09-27
IL105801A0 (en) 1993-09-22
TW368501B (en) 1999-09-01
LV12443B (en) 2000-06-20
MA22895A1 (fr) 1993-12-31
CN1036393C (zh) 1997-11-12
ZA933648B (en) 1993-11-25
NZ253190A (en) 1995-12-21
CZ291694A3 (en) 1995-03-15
HU9403387D0 (en) 1995-02-28
JPH08503923A (ja) 1996-04-30
NO304739B1 (no) 1999-02-08
LV12443A (en) 2000-03-20
AU675649B2 (en) 1997-02-13
SG48068A1 (en) 1998-04-17
CA2136553C (en) 2000-08-15
CA2136553A1 (en) 1993-12-09
PH31453A (en) 1998-11-03
AU4334393A (en) 1993-12-30
DK0649418T3 (da) 1999-07-12
EP0649418A1 (en) 1995-04-26
FI945538A0 (fi) 1994-11-25
CZ286905B6 (en) 2000-08-16
FI945538A7 (fi) 1994-11-25
DZ1694A1 (fr) 2002-02-17
SK281282B6 (sk) 2001-02-12
PL172904B1 (pl) 1997-12-31
NO944509D0 (no) 1994-11-24
KR100279132B1 (ko) 2001-01-15
HU211947A9 (en) 1996-01-29
UA27901C2 (uk) 2000-10-16
EP0649418B1 (en) 1998-10-28
GB9211172D0 (en) 1992-07-08

Similar Documents

Publication Publication Date Title
ES2123652T3 (es) 7-(2-aminoetil)-benzotiazolonas.
ES2108425T3 (es) Analogos de atp sustituidos con n-alquilo-2.
ES2058527T3 (es) Derivados de pirimidina condensados procedimiento y compuestos intermedios para su preparacion y composiciones farmaceuticas que los contienen.
HUP0101999A2 (hu) 4-Hidroxi-kinolin-3-karboxamid- és -hidrazid-származékok, ezeket tartalmazó gyógyászati készítmények, valamint e vegyületek alkalmazása
ES2059408T3 (es) Un proceso para la preparacion de un compuesto.
ES2055860T3 (es) Derivados 2-aminopirimidinona.
MX9300786A (es) Compuestos hipolipidaemicos.
ES2031876T3 (es) Un procedimiento para la preparacion de 5,6-dihidro-2-(fenil sustituido)-1,2,4,-triazin-3,5(2h,4h)-dionas.
ES2159922T3 (es) Nuevos derivados de bencimidazol, de benzoxazol y de benzotiazol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2063039T3 (es) Derivados de imidazo(1,2-b)piridazina.
ES2012648A6 (es) Procedimiento para la preparacion de nuevos derivados de 1,4-benzoxazina y 1,4-benzotiazina.
MX9400253A (es) Derivados de piperazina, proceso para su preparacion y composiciones farmaceuticas que los contienen.
ES8601956A1 (es) Un metodo para preparar derivados de 3-metilflavona
ES455741A1 (es) Un procedimiento para la preparacion de nuevos derivados de 1,3-bencenodimetanol.
DK0452204T3 (da) Hidtil ukendte 3-aminochromanderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
ATE37368T1 (de) Benzothiazolon-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
SE8603589D0 (sv) Metylendioxifenantren- och stilbenderivat
AR023332A1 (es) Compuestos derivados de benzamida sustituidos, proceso para su preparacion, formulaciones farmaceuticas que los comprenden, y metodo de tratamiento
ES2053544T3 (es) Un procedimiento para la preparacion de nuevos derivados de indol tetraciclicos.
ES2122982T3 (es) Derivados de tetrahidrocarbazol para la fabricacion de un medicamento para el tratamiento de una enfermedad en la que esta indicado un agonista similar a 5-ht1.
ES8801837A1 (es) Procedimiento de preparacion de 20-ceto-delta16-esteroides
ES2135383T3 (es) Pirido(3,4-b)pirrolo(1,2-e)(1,4,5)oxadiazepinas y compuestos analogos relacionados, un procedimiento para su preparacion y su uso como medicamentos.
ES2192827T3 (es) Derivados de 8h-(2,3-b)-pirrolicin-8-ona, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
PT100104A (pt) Processo para a preparacao de aminoalcanos substituidos
ECSP951538A (es) Derivados de quinoxalina utiles en terapia

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 649418

Country of ref document: ES