MX9400253A - Derivados de piperazina, proceso para su preparacion y composiciones farmaceuticas que los contienen. - Google Patents
Derivados de piperazina, proceso para su preparacion y composiciones farmaceuticas que los contienen.Info
- Publication number
- MX9400253A MX9400253A MX9400253A MX9400253A MX9400253A MX 9400253 A MX9400253 A MX 9400253A MX 9400253 A MX9400253 A MX 9400253A MX 9400253 A MX9400253 A MX 9400253A MX 9400253 A MX9400253 A MX 9400253A
- Authority
- MX
- Mexico
- Prior art keywords
- pct
- derivatives
- date
- piperazine
- contain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
Abstract
Esta invención se refiere a los derivados de piperacina, a los procesos para su preparación, a su uso y a las composiciones farmacéuticas que los contienen. Los nuevos compuestos actúan sobre el sistema nervioso central mediante el enlace a los receptores 5-HT (como será más completamente explicado más adelante) y de aquí que pueden ser usados como medicamentos para el tratamiento de humanos y otros mamíferos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939300195A GB9300195D0 (en) | 1993-01-06 | 1993-01-06 | Piperazine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9400253A true MX9400253A (es) | 1994-08-31 |
Family
ID=10728387
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9400253A MX9400253A (es) | 1993-01-06 | 1994-01-04 | Derivados de piperazina, proceso para su preparacion y composiciones farmaceuticas que los contienen. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5627177A (es) |
EP (1) | EP0678090B1 (es) |
JP (1) | JPH08505156A (es) |
AT (1) | ATE172193T1 (es) |
AU (1) | AU5819794A (es) |
DE (1) | DE69321609T2 (es) |
DK (1) | DK0678090T3 (es) |
ES (1) | ES2123756T3 (es) |
GB (1) | GB9300195D0 (es) |
IL (1) | IL108258A (es) |
MX (1) | MX9400253A (es) |
MY (1) | MY131381A (es) |
PH (1) | PH31303A (es) |
WO (1) | WO1994015919A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5434158A (en) * | 1994-04-26 | 1995-07-18 | Merck & Co., Inc. | Spiro-substituted azacycles as neurokinin-3 antagonists |
GB9411099D0 (en) * | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
CA2194984C (en) * | 1994-07-26 | 2002-07-02 | John Eugene Macor | 4-indole derivatives as serotonin agonists and antagonists |
GB9419024D0 (en) * | 1994-09-21 | 1994-11-09 | Wyeth John & Brother Ltd | Bicyclic carboxamides |
US5607936A (en) * | 1994-09-30 | 1997-03-04 | Merck & Co., Inc. | Substituted aryl piperazines as neurokinin antagonists |
FR2735127B1 (fr) * | 1995-06-09 | 1997-08-22 | Pf Medicament | Nouvelles piperazines heteroaromatiques utiles comme medicaments. |
US5990114A (en) * | 1996-02-28 | 1999-11-23 | Recordati, S.A., Chemical And Pharmaceutical Company | Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence |
DE69819266T2 (de) * | 1997-09-02 | 2004-07-29 | Duphar International Research B.V. | Piperidin- und Piperazin Derivate als 5-HT1-Rezeptor-Agonisten |
EP0900792B1 (en) * | 1997-09-02 | 2003-10-29 | Duphar International Research B.V | Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists |
EP0982304B1 (en) * | 1998-06-30 | 2002-10-02 | Eli Lilly And Company | Piperidine derivatives having effects on serotonin related systems |
US6743796B2 (en) | 2001-05-07 | 2004-06-01 | Wyeth | Piperazinyl-isatins |
US7071197B2 (en) * | 2002-06-14 | 2006-07-04 | Recordati S.A. | N,N-disubstituted diazocycloalkanes |
ITMI20021327A1 (it) * | 2002-06-14 | 2003-12-15 | Recordati Chem Pharm | Nuove ossialchilpiperazine |
US20040072839A1 (en) * | 2002-06-14 | 2004-04-15 | Amedeo Leonardi | 1-Phenylalkylpiperazines |
GB0316915D0 (en) * | 2003-07-18 | 2003-08-20 | Glaxo Group Ltd | Compounds |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2140374T3 (es) * | 1989-04-22 | 2000-03-01 | American Home Prod | Derivados de piperazina funcionalizados con alquilos terciarios. |
US5382583A (en) * | 1989-04-22 | 1995-01-17 | John Wyeth & Brother, Limited | Piperazine derivatives |
KR0173310B1 (ko) * | 1989-04-22 | 1999-02-01 | 폴 에이 리쳐 | 피페라진 유도체 |
DK203990D0 (da) * | 1990-08-24 | 1990-08-24 | Novo Nordisk As | Piperazinylderivater |
GB9022821D0 (en) * | 1990-10-19 | 1990-12-05 | Wyeth John & Brother Ltd | Piperazine derivatives |
AU645681B2 (en) * | 1991-05-02 | 1994-01-20 | John Wyeth & Brother Limited | Piperazine derivatives |
GB9125900D0 (en) * | 1991-12-05 | 1992-02-05 | Wyeth John & Brother Ltd | Piperazine derivatives |
-
1993
- 1993-01-06 GB GB939300195A patent/GB9300195D0/en active Pending
- 1993-12-21 MY MYPI93002785A patent/MY131381A/en unknown
- 1993-12-24 WO PCT/GB1993/002660 patent/WO1994015919A1/en active IP Right Grant
- 1993-12-24 AT AT94903945T patent/ATE172193T1/de active
- 1993-12-24 DK DK94903945T patent/DK0678090T3/da active
- 1993-12-24 EP EP94903945A patent/EP0678090B1/en not_active Expired - Lifetime
- 1993-12-24 DE DE69321609T patent/DE69321609T2/de not_active Expired - Fee Related
- 1993-12-24 US US08/446,601 patent/US5627177A/en not_active Expired - Lifetime
- 1993-12-24 ES ES94903945T patent/ES2123756T3/es not_active Expired - Lifetime
- 1993-12-24 JP JP6515781A patent/JPH08505156A/ja active Pending
- 1993-12-24 AU AU58197/94A patent/AU5819794A/en not_active Abandoned
-
1994
- 1994-01-03 IL IL10825894A patent/IL108258A/en not_active IP Right Cessation
- 1994-01-04 MX MX9400253A patent/MX9400253A/es not_active IP Right Cessation
- 1994-01-05 PH PH47581D patent/PH31303A/en unknown
Also Published As
Publication number | Publication date |
---|---|
US5627177A (en) | 1997-05-06 |
EP0678090B1 (en) | 1998-10-14 |
PH31303A (en) | 1998-07-06 |
GB9300195D0 (en) | 1993-03-03 |
ATE172193T1 (de) | 1998-10-15 |
ES2123756T3 (es) | 1999-01-16 |
EP0678090A1 (en) | 1995-10-25 |
DE69321609T2 (de) | 1999-03-25 |
WO1994015919A1 (en) | 1994-07-21 |
DE69321609D1 (de) | 1998-11-19 |
MY131381A (en) | 2007-08-30 |
DK0678090T3 (da) | 1999-06-23 |
JPH08505156A (ja) | 1996-06-04 |
AU5819794A (en) | 1994-08-15 |
IL108258A0 (en) | 1994-04-12 |
IL108258A (en) | 1998-12-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9400253A (es) | Derivados de piperazina, proceso para su preparacion y composiciones farmaceuticas que los contienen. | |
MX9206939A (es) | Derivados de piperazina, procedimiento para su preparacion y composicion farmaceutica que los comprende | |
DK0677046T3 (da) | Piperazinderivater som 5-HT-antagonister. | |
ES2098023T3 (es) | Compuestos de estructura guanidinica y composiciones farmaceuticas que los contienen. | |
DE69719974T2 (de) | Chinolinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
DK0689534T3 (da) | Amidderivater som 5-HT1A-ligander | |
MX9400165A (es) | Derivados de ter-butilergolina, proceso para su produccion y composiciones farmaceuticas que los contienen. | |
KR970706280A (ko) | 5-HT1A 길항제로서의 비사이클릭 카복스아미드(Bicyclic carboxamides as 5-HT1 antagonists) | |
DK0687257T3 (da) | 4-amino-2-(hetero)aryl-butanamider anvendelige som 5HT1A-antagonister | |
AU3626189A (en) | New derivatives of phenothiazine, their preparation and the compositions which contain them | |
TW257758B (en) | Piperazine derivatives (1) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
MM | Annulment or lapse due to non-payment of fees |