DK0678090T3 - Piperazinderivater - Google Patents
PiperazinderivaterInfo
- Publication number
- DK0678090T3 DK0678090T3 DK94903945T DK94903945T DK0678090T3 DK 0678090 T3 DK0678090 T3 DK 0678090T3 DK 94903945 T DK94903945 T DK 94903945T DK 94903945 T DK94903945 T DK 94903945T DK 0678090 T3 DK0678090 T3 DK 0678090T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- date
- sec
- aryl
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939300195A GB9300195D0 (en) | 1993-01-06 | 1993-01-06 | Piperazine derivatives |
| PCT/GB1993/002660 WO1994015919A1 (en) | 1993-01-06 | 1993-12-24 | Piperazine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0678090T3 true DK0678090T3 (da) | 1999-06-23 |
Family
ID=10728387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94903945T DK0678090T3 (da) | 1993-01-06 | 1993-12-24 | Piperazinderivater |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5627177A (es) |
| EP (1) | EP0678090B1 (es) |
| JP (1) | JPH08505156A (es) |
| AT (1) | ATE172193T1 (es) |
| AU (1) | AU5819794A (es) |
| DE (1) | DE69321609T2 (es) |
| DK (1) | DK0678090T3 (es) |
| ES (1) | ES2123756T3 (es) |
| GB (1) | GB9300195D0 (es) |
| IL (1) | IL108258A (es) |
| MX (1) | MX9400253A (es) |
| MY (1) | MY131381A (es) |
| PH (1) | PH31303A (es) |
| WO (1) | WO1994015919A1 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5434158A (en) * | 1994-04-26 | 1995-07-18 | Merck & Co., Inc. | Spiro-substituted azacycles as neurokinin-3 antagonists |
| GB9411099D0 (en) * | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
| CA2194984C (en) * | 1994-07-26 | 2002-07-02 | John Eugene Macor | 4-indole derivatives as serotonin agonists and antagonists |
| GB9419024D0 (en) * | 1994-09-21 | 1994-11-09 | Wyeth John & Brother Ltd | Bicyclic carboxamides |
| US5607936A (en) * | 1994-09-30 | 1997-03-04 | Merck & Co., Inc. | Substituted aryl piperazines as neurokinin antagonists |
| FR2735127B1 (fr) * | 1995-06-09 | 1997-08-22 | Pf Medicament | Nouvelles piperazines heteroaromatiques utiles comme medicaments. |
| US5990114A (en) * | 1996-02-28 | 1999-11-23 | Recordati, S.A., Chemical And Pharmaceutical Company | Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence |
| ATE253058T1 (de) * | 1997-09-02 | 2003-11-15 | Duphar Int Res | Piperidin- und piperazin derivate als 5-ht1- rezeptor-agonisten |
| EP0900792B1 (en) * | 1997-09-02 | 2003-10-29 | Duphar International Research B.V | Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists |
| CO5080791A1 (es) * | 1998-06-30 | 2001-09-25 | Lilly Co Eli | Derivados de la piperidina que tienen efectos sobre sistemas con serotonina |
| US6743796B2 (en) | 2001-05-07 | 2004-06-01 | Wyeth | Piperazinyl-isatins |
| ITMI20021327A1 (it) * | 2002-06-14 | 2003-12-15 | Recordati Chem Pharm | Nuove ossialchilpiperazine |
| US7071197B2 (en) * | 2002-06-14 | 2006-07-04 | Recordati S.A. | N,N-disubstituted diazocycloalkanes |
| US20040072839A1 (en) * | 2002-06-14 | 2004-04-15 | Amedeo Leonardi | 1-Phenylalkylpiperazines |
| GB0316915D0 (en) * | 2003-07-18 | 2003-08-20 | Glaxo Group Ltd | Compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0395313T3 (da) * | 1989-04-22 | 2000-06-19 | American Home Prod | Tertiære alkyl-funktionaliserede piperazin-derivater |
| US5382583A (en) * | 1989-04-22 | 1995-01-17 | John Wyeth & Brother, Limited | Piperazine derivatives |
| EP0395312B1 (en) * | 1989-04-22 | 1999-05-12 | JOHN WYETH & BROTHER LIMITED | Piperazine derivatives |
| DK203990D0 (da) * | 1990-08-24 | 1990-08-24 | Novo Nordisk As | Piperazinylderivater |
| GB9022821D0 (en) * | 1990-10-19 | 1990-12-05 | Wyeth John & Brother Ltd | Piperazine derivatives |
| AU645681B2 (en) * | 1991-05-02 | 1994-01-20 | John Wyeth & Brother Limited | Piperazine derivatives |
| GB9125900D0 (en) * | 1991-12-05 | 1992-02-05 | Wyeth John & Brother Ltd | Piperazine derivatives |
-
1993
- 1993-01-06 GB GB939300195A patent/GB9300195D0/en active Pending
- 1993-12-21 MY MYPI93002785A patent/MY131381A/en unknown
- 1993-12-24 ES ES94903945T patent/ES2123756T3/es not_active Expired - Lifetime
- 1993-12-24 JP JP6515781A patent/JPH08505156A/ja active Pending
- 1993-12-24 US US08/446,601 patent/US5627177A/en not_active Expired - Lifetime
- 1993-12-24 EP EP94903945A patent/EP0678090B1/en not_active Expired - Lifetime
- 1993-12-24 AT AT94903945T patent/ATE172193T1/de active
- 1993-12-24 DE DE69321609T patent/DE69321609T2/de not_active Expired - Fee Related
- 1993-12-24 DK DK94903945T patent/DK0678090T3/da active
- 1993-12-24 AU AU58197/94A patent/AU5819794A/en not_active Abandoned
- 1993-12-24 WO PCT/GB1993/002660 patent/WO1994015919A1/en active IP Right Grant
-
1994
- 1994-01-03 IL IL10825894A patent/IL108258A/en not_active IP Right Cessation
- 1994-01-04 MX MX9400253A patent/MX9400253A/es not_active IP Right Cessation
- 1994-01-05 PH PH47581D patent/PH31303A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL108258A (en) | 1998-12-06 |
| US5627177A (en) | 1997-05-06 |
| AU5819794A (en) | 1994-08-15 |
| DE69321609T2 (de) | 1999-03-25 |
| IL108258A0 (en) | 1994-04-12 |
| JPH08505156A (ja) | 1996-06-04 |
| MY131381A (en) | 2007-08-30 |
| GB9300195D0 (en) | 1993-03-03 |
| PH31303A (en) | 1998-07-06 |
| EP0678090B1 (en) | 1998-10-14 |
| DE69321609D1 (de) | 1998-11-19 |
| ATE172193T1 (de) | 1998-10-15 |
| MX9400253A (es) | 1994-08-31 |
| WO1994015919A1 (en) | 1994-07-21 |
| ES2123756T3 (es) | 1999-01-16 |
| EP0678090A1 (en) | 1995-10-25 |
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