ES2056239T3 - Glicosaminoglicanos selectivamente o-acilados. - Google Patents

Glicosaminoglicanos selectivamente o-acilados.

Info

Publication number
ES2056239T3
ES2056239T3 ES89402086T ES89402086T ES2056239T3 ES 2056239 T3 ES2056239 T3 ES 2056239T3 ES 89402086 T ES89402086 T ES 89402086T ES 89402086 T ES89402086 T ES 89402086T ES 2056239 T3 ES2056239 T3 ES 2056239T3
Authority
ES
Spain
Prior art keywords
glycosaminoglycans
selectively
acilados
groups
unaltered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89402086T
Other languages
English (en)
Inventor
Maurice Petitou
Jean-Claude Lormeau
Jean Choay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elf Sanofi SA
Original Assignee
Elf Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elf Sanofi SA filed Critical Elf Sanofi SA
Application granted granted Critical
Publication of ES2056239T3 publication Critical patent/ES2056239T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)

Abstract

LOS GLICOSAMINOGLICANOS DEL INVENTO SON SELECTIVAMENTE O-ACILADOS DE MODO MODULABLE SOBRE SUS GRUPOS -OH LIBRES, LOS GRUPOS FUNCIONALES CARBOXILICOS O AMINADOS NO SON ALTERADOS. ESTOS COMPUESTOS TIENEN UNA ACTIVIDAD FARMACOLOGICA DE MUY LARGA DURACION.
ES89402086T 1988-07-21 1989-07-21 Glicosaminoglicanos selectivamente o-acilados. Expired - Lifetime ES2056239T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8809885A FR2634485B1 (fr) 1988-07-21 1988-07-21 Glycosaminoglycanes selectivement o-acyles, leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
ES2056239T3 true ES2056239T3 (es) 1994-10-01

Family

ID=9368648

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89402086T Expired - Lifetime ES2056239T3 (es) 1988-07-21 1989-07-21 Glicosaminoglicanos selectivamente o-acilados.

Country Status (23)

Country Link
EP (1) EP0356275B1 (es)
JP (1) JPH0273801A (es)
KR (1) KR910002889A (es)
AT (1) ATE108804T1 (es)
AU (1) AU620632B2 (es)
DD (1) DD285606A5 (es)
DE (1) DE68916878T2 (es)
DK (1) DK362789A (es)
ES (1) ES2056239T3 (es)
FI (1) FI893518A (es)
FR (1) FR2634485B1 (es)
HU (1) HU206222B (es)
IE (1) IE892367L (es)
IL (1) IL91058A0 (es)
MA (1) MA21602A1 (es)
NO (1) NO892986L (es)
NZ (1) NZ230041A (es)
OA (1) OA09125A (es)
PT (1) PT91249B (es)
RU (1) RU1831487C (es)
TN (1) TNSN89082A1 (es)
YU (1) YU172789A (es)
ZA (1) ZA895581B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2669932B1 (fr) * 1990-12-03 1994-07-01 Sanofi Sa Nouvel heparosane-n,o-sulfate, son procede de preparation et les compositions pharmaceutiques qui le contiennent.
US5834444A (en) * 1991-07-03 1998-11-10 Hyal Pharmaceutical Corporation Hyaluronic acid and salts thereof inhibit arterial restenosis
US5990095A (en) 1991-07-03 1999-11-23 Hyal Pharmaceutical Corporation Use of hyaluronic acid and forms to prevent arterial restenosis
US5498775A (en) * 1994-11-07 1996-03-12 American Home Products Corporation Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation
IL115745A (en) * 1994-11-07 2000-11-21 American Home Prod Acylated benzylglycosides and pharmaceutical compositions containing them
US5565432A (en) * 1994-11-07 1996-10-15 American Home Products Corporation Smooth muscle cell proliferation inhibitors
IT1286510B1 (it) * 1996-11-29 1998-07-15 Cooperativa Centro Ricerche Po Esteri butirrici ad attivita' antiproliferativa e composizioni farmaceutiche che li contengono
US7081448B2 (en) 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en) 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
CA2317305A1 (en) 2000-08-29 2002-02-28 Tassos P. Anastassiades Method of enhancing chondrocyte cell growth and glycosaminoglycan production
KR20030057040A (ko) * 2001-12-28 2003-07-04 주식회사 효성 글루코사민 유도체 및 그의 제조 방법
KR100790007B1 (ko) * 2006-12-28 2008-01-02 경상대학교산학협력단 미색류 껍질로부터 글리코사미노글리칸의 정제방법
CN103209997B (zh) * 2010-09-14 2016-03-16 国立大学法人宫崎大学 高纯度肝素及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3066M (fr) * 1963-08-07 1965-01-18 Roussel Uclaf Nouveau médicament notamment pour le traitement de l'hyperlipémie post-prandiale ou chronique.
JPS469327B1 (es) * 1966-03-31 1971-03-09
JPS52111983A (en) * 1976-03-18 1977-09-20 Teijin Ltd Preparation of heparin derivatives
US4331697A (en) * 1980-09-02 1982-05-25 Teijin Limited Novel heparin derivative, method for production thereof, and method for rendering biomedical materials antithrombotic by use of the novel heparin derivative
FR2584728B1 (fr) * 1985-07-12 1987-11-20 Choay Sa Procede de sulfatation de glycosaminoglycanes et de leurs fragments
JP5410580B1 (ja) * 2012-08-09 2014-02-05 日本特殊陶業株式会社 配線基板

Also Published As

Publication number Publication date
DE68916878D1 (de) 1994-08-25
DK362789D0 (da) 1989-07-21
DD285606A5 (de) 1990-12-19
AU620632B2 (en) 1992-02-20
IE892367L (en) 1990-01-21
AU3885689A (en) 1990-01-25
MA21602A1 (fr) 1990-04-01
HU206222B (en) 1992-09-28
EP0356275A1 (fr) 1990-02-28
ATE108804T1 (de) 1994-08-15
RU1831487C (ru) 1993-07-30
IL91058A0 (en) 1990-02-09
FI893518A0 (fi) 1989-07-21
OA09125A (fr) 1991-10-31
FR2634485B1 (fr) 1992-02-28
YU172789A (en) 1991-08-31
DK362789A (da) 1990-01-22
NZ230041A (en) 1991-09-25
FI893518A (fi) 1990-01-22
NO892986L (no) 1990-01-22
PT91249B (pt) 1995-05-04
DE68916878T2 (de) 1995-03-16
KR910002889A (ko) 1991-02-26
JPH0273801A (ja) 1990-03-13
HUT50489A (en) 1990-02-28
TNSN89082A1 (fr) 1991-02-04
ZA895581B (en) 1990-04-25
EP0356275B1 (fr) 1994-07-20
PT91249A (pt) 1990-02-08
NO892986D0 (no) 1989-07-20
FR2634485A1 (fr) 1990-01-26

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