DE68916878D1 - Selektiv O-acylierte Glycosaminoglykane. - Google Patents

Selektiv O-acylierte Glycosaminoglykane.

Info

Publication number
DE68916878D1
DE68916878D1 DE68916878T DE68916878T DE68916878D1 DE 68916878 D1 DE68916878 D1 DE 68916878D1 DE 68916878 T DE68916878 T DE 68916878T DE 68916878 T DE68916878 T DE 68916878T DE 68916878 D1 DE68916878 D1 DE 68916878D1
Authority
DE
Germany
Prior art keywords
selectively
glycosaminoglycans
acylated
acylated glycosaminoglycans
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68916878T
Other languages
English (en)
Other versions
DE68916878T2 (de
Inventor
Maurice Petitou
Jean-Claude Lormeau
Jean Choay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elf Sanofi SA
Original Assignee
Elf Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elf Sanofi SA filed Critical Elf Sanofi SA
Publication of DE68916878D1 publication Critical patent/DE68916878D1/de
Application granted granted Critical
Publication of DE68916878T2 publication Critical patent/DE68916878T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
DE68916878T 1988-07-21 1989-07-21 Selektiv O-acylierte Glycosaminoglykane. Expired - Fee Related DE68916878T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8809885A FR2634485B1 (fr) 1988-07-21 1988-07-21 Glycosaminoglycanes selectivement o-acyles, leur preparation et compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
DE68916878D1 true DE68916878D1 (de) 1994-08-25
DE68916878T2 DE68916878T2 (de) 1995-03-16

Family

ID=9368648

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68916878T Expired - Fee Related DE68916878T2 (de) 1988-07-21 1989-07-21 Selektiv O-acylierte Glycosaminoglykane.

Country Status (23)

Country Link
EP (1) EP0356275B1 (de)
JP (1) JPH0273801A (de)
KR (1) KR910002889A (de)
AT (1) ATE108804T1 (de)
AU (1) AU620632B2 (de)
DD (1) DD285606A5 (de)
DE (1) DE68916878T2 (de)
DK (1) DK362789A (de)
ES (1) ES2056239T3 (de)
FI (1) FI893518A (de)
FR (1) FR2634485B1 (de)
HU (1) HU206222B (de)
IE (1) IE892367L (de)
IL (1) IL91058A0 (de)
MA (1) MA21602A1 (de)
NO (1) NO892986L (de)
NZ (1) NZ230041A (de)
OA (1) OA09125A (de)
PT (1) PT91249B (de)
RU (1) RU1831487C (de)
TN (1) TNSN89082A1 (de)
YU (1) YU172789A (de)
ZA (1) ZA895581B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2669932B1 (fr) * 1990-12-03 1994-07-01 Sanofi Sa Nouvel heparosane-n,o-sulfate, son procede de preparation et les compositions pharmaceutiques qui le contiennent.
US5990095A (en) 1991-07-03 1999-11-23 Hyal Pharmaceutical Corporation Use of hyaluronic acid and forms to prevent arterial restenosis
US5834444A (en) * 1991-07-03 1998-11-10 Hyal Pharmaceutical Corporation Hyaluronic acid and salts thereof inhibit arterial restenosis
IL115745A (en) * 1994-11-07 2000-11-21 American Home Prod Acylated benzylglycosides and pharmaceutical compositions containing them
US5498775A (en) * 1994-11-07 1996-03-12 American Home Products Corporation Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation
US5565432A (en) * 1994-11-07 1996-10-15 American Home Products Corporation Smooth muscle cell proliferation inhibitors
IT1286510B1 (it) * 1996-11-29 1998-07-15 Cooperativa Centro Ricerche Po Esteri butirrici ad attivita' antiproliferativa e composizioni farmaceutiche che li contengono
US7081448B2 (en) 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en) 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
CA2317305A1 (en) 2000-08-29 2002-02-28 Tassos P. Anastassiades Method of enhancing chondrocyte cell growth and glycosaminoglycan production
KR20030057040A (ko) * 2001-12-28 2003-07-04 주식회사 효성 글루코사민 유도체 및 그의 제조 방법
KR100790007B1 (ko) * 2006-12-28 2008-01-02 경상대학교산학협력단 미색류 껍질로부터 글리코사미노글리칸의 정제방법
CA3020369C (en) * 2010-09-14 2019-11-26 University Of Miyazaki High purity heparin and production method therefor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3066M (fr) * 1963-08-07 1965-01-18 Roussel Uclaf Nouveau médicament notamment pour le traitement de l'hyperlipémie post-prandiale ou chronique.
JPS469327B1 (de) * 1966-03-31 1971-03-09
JPS52111983A (en) * 1976-03-18 1977-09-20 Teijin Ltd Preparation of heparin derivatives
US4331697A (en) * 1980-09-02 1982-05-25 Teijin Limited Novel heparin derivative, method for production thereof, and method for rendering biomedical materials antithrombotic by use of the novel heparin derivative
FR2584728B1 (fr) * 1985-07-12 1987-11-20 Choay Sa Procede de sulfatation de glycosaminoglycanes et de leurs fragments
JP5410580B1 (ja) * 2012-08-09 2014-02-05 日本特殊陶業株式会社 配線基板

Also Published As

Publication number Publication date
IE892367L (en) 1990-01-21
MA21602A1 (fr) 1990-04-01
DD285606A5 (de) 1990-12-19
AU3885689A (en) 1990-01-25
TNSN89082A1 (fr) 1991-02-04
PT91249A (pt) 1990-02-08
FR2634485A1 (fr) 1990-01-26
NZ230041A (en) 1991-09-25
RU1831487C (ru) 1993-07-30
DK362789A (da) 1990-01-22
HUT50489A (en) 1990-02-28
ATE108804T1 (de) 1994-08-15
YU172789A (en) 1991-08-31
NO892986D0 (no) 1989-07-20
DE68916878T2 (de) 1995-03-16
JPH0273801A (ja) 1990-03-13
FR2634485B1 (fr) 1992-02-28
NO892986L (no) 1990-01-22
AU620632B2 (en) 1992-02-20
PT91249B (pt) 1995-05-04
ES2056239T3 (es) 1994-10-01
DK362789D0 (da) 1989-07-21
HU206222B (en) 1992-09-28
OA09125A (fr) 1991-10-31
FI893518A (fi) 1990-01-22
IL91058A0 (en) 1990-02-09
KR910002889A (ko) 1991-02-26
FI893518A0 (fi) 1989-07-21
EP0356275B1 (de) 1994-07-20
EP0356275A1 (de) 1990-02-28
ZA895581B (en) 1990-04-25

Similar Documents

Publication Publication Date Title
ES2056239T3 (es) Glicosaminoglicanos selectivamente o-acilados.
DE3887896D1 (de) Angioplastie-anordnung.
DE68924458T2 (de) Mustererkennungsverfahren.
DE68903967T2 (de) Akkumulator - brennstoffeinspritzduese.
DE68907595T2 (de) Zerstäubungsdüsen.
DE68915309D1 (de) Zerstäuber.
IT8822582A0 (it) Carrello ferroviario sterzante.
FI882409A (fi) Svetsbart mikroporoest florplaoster foer medicinskt bruk. pi path slues6208 s880415 mlues6205 m881130
DE68902704D1 (de) Duese mit freiem durchgang.
DE3882062D1 (de) System zum vergleichen von mustern.
FI883266A0 (fi) 4-aminosubstituerade 1,2-dihydronaftalenderivat.
FI893512A (fi) Bordetella pertussis-vaccin.
ATE101530T1 (de) Angioplastie-anordnung.
ATE91438T1 (de) Zerstaeubungsduesen.
NO904423L (no) Dyseanordning.
IT8914913V0 (it) Specchio poliangolare fortuna.
ATE85823T1 (de) Leitplankenanordnung.
ES1005774Y (es) Mando neumatico perfeccionado.
ES1008564Y (es) Guardarrail perfeccionado.
ES1023370Y (es) Pistas de juguete perfeccionadas.
FI884355A (fi) Centrerande ballonringkonstruktion foer transluminal angioplastiakateter.
NO883034D0 (no) Engangs injeksjonssproeyte.
ES1005437Y (es) Broche perfeccionado.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee