ES2051781T3 - Derivados de imidazodiacepina. - Google Patents
Derivados de imidazodiacepina.Info
- Publication number
- ES2051781T3 ES2051781T3 ES88103739T ES88103739T ES2051781T3 ES 2051781 T3 ES2051781 T3 ES 2051781T3 ES 88103739 T ES88103739 T ES 88103739T ES 88103739 T ES88103739 T ES 88103739T ES 2051781 T3 ES2051781 T3 ES 2051781T3
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- derivatives
- low
- dimethylene
- trimethylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- GXGJIOMUZAGVEH-UHFFFAOYSA-N Chamazulene Chemical class CCC1=CC=C(C)C2=CC=C(C)C2=C1 GXGJIOMUZAGVEH-UHFFFAOYSA-N 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000003258 trimethylene group Chemical class [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 2
- -1 HYDROGEN ATOMS Chemical group 0.000 abstract 1
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical compound [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 abstract 1
- 230000002082 anti-convulsion Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
- 230000003285 pharmacodynamic effect Effects 0.000 abstract 1
- 230000002040 relaxant effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH88087 | 1987-03-10 | ||
| CH5988 | 1988-01-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2051781T3 true ES2051781T3 (es) | 1994-07-01 |
Family
ID=25683391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88103739T Expired - Lifetime ES2051781T3 (es) | 1987-03-10 | 1988-03-09 | Derivados de imidazodiacepina. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4863920A (OSRAM) |
| EP (1) | EP0285837B1 (OSRAM) |
| KR (1) | KR880011159A (OSRAM) |
| AU (1) | AU604300B2 (OSRAM) |
| CA (1) | CA1327571C (OSRAM) |
| DE (1) | DE3872559D1 (OSRAM) |
| DK (1) | DK127288A (OSRAM) |
| ES (1) | ES2051781T3 (OSRAM) |
| FI (1) | FI880814A7 (OSRAM) |
| GR (1) | GR3005909T3 (OSRAM) |
| HU (1) | HU201763B (OSRAM) |
| IL (1) | IL85624A0 (OSRAM) |
| MC (1) | MC1918A1 (OSRAM) |
| NO (1) | NO167027C (OSRAM) |
| NZ (1) | NZ223736A (OSRAM) |
| PT (1) | PT86925B (OSRAM) |
| YU (1) | YU47988A (OSRAM) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1327572C (en) * | 1988-08-31 | 1994-03-08 | F. Hoffmann-La Roche Ag | Imidazodiazepine derivatives |
| GB8909700D0 (en) * | 1989-04-27 | 1989-06-14 | Roussel Lab Ltd | Chemical compounds |
| CA2015336A1 (en) * | 1989-05-19 | 1990-11-19 | F. Hoffmann-La Roche Ag | Imidazodiazepines for the treatment of neurological symptoms |
| AU676702B2 (en) * | 1992-12-04 | 1997-03-20 | Janssen Pharmaceutica N.V. | Antiallergic imidazo{1,2-a}(pyrrolo, thieno or furano){2,3-d}azepine derivatives |
| KR20070033032A (ko) | 2004-07-16 | 2007-03-23 | 프로테오시스 악티엔게젤샤프트 | 세포보호제로서 ｐａｒｐ 및 ｓｉｒ 조절 활성을 갖는무스카린 길항제 |
| EP2387405A2 (en) | 2009-01-13 | 2011-11-23 | ProteoSys AG | Pirenzepine as an agent in cancer treatment |
| BR112018009550A2 (pt) | 2015-11-13 | 2018-11-06 | Mavalon Therapeutics Ltd | derivados de 1,4-benzodiazepinona tricíclica substituída como moduladores alostéricos de receptores de glutamato metabotrópico de grupo ii |
| AU2018265615A1 (en) | 2017-05-12 | 2019-10-03 | Domain Therapeutics | Substituted heterocyclic compounds as allosteric modulators of group II metabotropic glutamate receptors |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA755418B (en) * | 1974-09-11 | 1977-06-29 | Hoffmann La Roche | Diazepine derivatives |
| US4280957A (en) * | 1974-09-11 | 1981-07-28 | Hoffmann-La Roche Inc. | Imidazodiazepines and processes therefor |
| CA1143728A (en) * | 1979-10-04 | 1983-03-29 | Max Gerecke | Imidazodiazepine derivatives |
| CA1174673A (en) * | 1981-02-27 | 1984-09-18 | Walter Hunkeler | Imidazodiazepines |
| DK151808C (da) * | 1982-11-16 | 1988-06-20 | Ferrosan As | Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater |
| IL74070A (en) * | 1984-01-19 | 1988-12-30 | Hoffmann La Roche | Imidazodiazepine derivatives,their manufacture and pharmaceutical compositions containing them |
| DE3661197D1 (en) * | 1985-05-17 | 1988-12-22 | Ferrosan As | Oxadiazolylimidazobenzodiazepines, process for their preparation and pharmaceutical compositions |
| DK174086D0 (da) * | 1986-04-16 | 1986-04-16 | Ferrosan As | Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme |
| GB8720414D0 (en) * | 1987-08-28 | 1987-10-07 | Roussel Lab Ltd | Chemical compounds |
| CA1327572C (en) * | 1988-08-31 | 1994-03-08 | F. Hoffmann-La Roche Ag | Imidazodiazepine derivatives |
-
1988
- 1988-02-22 FI FI880814A patent/FI880814A7/fi not_active Application Discontinuation
- 1988-02-23 CA CA000559547A patent/CA1327571C/en not_active Expired - Fee Related
- 1988-03-03 NZ NZ223736A patent/NZ223736A/en unknown
- 1988-03-03 IL IL85624A patent/IL85624A0/xx unknown
- 1988-03-03 US US07/163,441 patent/US4863920A/en not_active Expired - Fee Related
- 1988-03-04 AU AU12710/88A patent/AU604300B2/en not_active Ceased
- 1988-03-07 MC MC881954A patent/MC1918A1/xx unknown
- 1988-03-07 HU HU881085A patent/HU201763B/hu not_active IP Right Cessation
- 1988-03-09 NO NO881054A patent/NO167027C/no unknown
- 1988-03-09 DE DE8888103739T patent/DE3872559D1/de not_active Expired - Lifetime
- 1988-03-09 KR KR1019880002420A patent/KR880011159A/ko not_active Withdrawn
- 1988-03-09 EP EP88103739A patent/EP0285837B1/de not_active Expired - Lifetime
- 1988-03-09 YU YU00479/88A patent/YU47988A/xx unknown
- 1988-03-09 DK DK127288A patent/DK127288A/da not_active Application Discontinuation
- 1988-03-09 ES ES88103739T patent/ES2051781T3/es not_active Expired - Lifetime
- 1988-03-09 PT PT86925A patent/PT86925B/pt not_active IP Right Cessation
-
1992
- 1992-10-08 GR GR920402228T patent/GR3005909T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO167027B (no) | 1991-06-17 |
| NZ223736A (en) | 1992-01-29 |
| IL85624A0 (en) | 1988-08-31 |
| KR880011159A (ko) | 1988-10-26 |
| PT86925B (pt) | 1992-05-29 |
| NO167027C (no) | 1991-09-25 |
| PT86925A (pt) | 1988-04-01 |
| US4863920A (en) | 1989-09-05 |
| AU604300B2 (en) | 1990-12-13 |
| DE3872559D1 (de) | 1992-08-13 |
| DK127288A (da) | 1988-09-11 |
| MC1918A1 (fr) | 1989-04-06 |
| YU47988A (en) | 1991-04-30 |
| EP0285837B1 (de) | 1992-07-08 |
| NO881054D0 (no) | 1988-03-09 |
| HUT47282A (en) | 1989-02-28 |
| AU1271088A (en) | 1988-09-15 |
| EP0285837A1 (de) | 1988-10-12 |
| NO881054L (no) | 1988-09-12 |
| HU201763B (en) | 1990-12-28 |
| FI880814A7 (fi) | 1988-09-11 |
| GR3005909T3 (OSRAM) | 1993-06-07 |
| DK127288D0 (da) | 1988-03-09 |
| FI880814A0 (fi) | 1988-02-22 |
| CA1327571C (en) | 1994-03-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Lemmer et al. | Diurnal rhythm in the central dopamine turnover in the rat | |
| ES2138977T3 (es) | Agonistas muscarinicos. | |
| ES2149215T3 (es) | Bencilaminoquinuclidinas sustituidas como antagonistas de la sustancia p. | |
| ES2059207T3 (es) | Procedimiento para la preparacion de derivados del taxano, nuevos derivados obtenidos y composiciones farmaceuticas que les contienen. | |
| ES2189330T3 (es) | Derivados heterociclicos n6 de la adenosina sustituidos. | |
| ES2131106T3 (es) | Compuestos de benzotiazepina hipolipidemicos. | |
| UY23657A1 (es) | Procedimiento para la preparacion de derivados de indol | |
| ES2154262T3 (es) | Uso de compuestos macrolidos para enfermedades oculares. | |
| ES2038622T3 (es) | Utilizacion de un derivado de naftaleno y su procedimiento de preparacion. | |
| CO4700455A1 (es) | Derivados tetraciclicos y proceso para su preparacion | |
| ES2051781T3 (es) | Derivados de imidazodiacepina. | |
| ES2051772T3 (es) | 2-sustituido-e-fusionado-(1,2,4)-triazol(1,5-c)pirimidinas, composiciones farmaceuticas y sus usos. | |
| AR241025A2 (es) | Dispersiones de brillo perlino no ionicas, capaces de fluir" | |
| ES2061580T3 (es) | Compuestos de 3,7-diazabiciclo(3,3,1)nonano, asi como procedimiento para su preparacion y medicamentos que contienen estos compuestos. | |
| ES2073396T3 (es) | Nuevos derivados ciclicos del acido antranilico y procedimiento para su preparacion. | |
| ES2070238T3 (es) | Emulsion de lipidos que contiene un analogo de prostaglandina. | |
| ES2055717T3 (es) | Derivados de benzo- y tieno-3,4-dihidro-piridina, procedimientos para su preparacion y medicamentos que contienen estos compuestos. | |
| MX9300205A (es) | Compuestos policiclicos disubstituidos y composicion farmaceutica que los contiene. | |
| ES474242A1 (es) | Un procedimiento para la produccion de compuestos tricicli- cos. | |
| FR1245579A (fr) | Procédé de préparation de produits d'addition alcalins de certains hydrocarbures aromatiques | |
| ES2038693T3 (es) | Nuevos acidos aminometanodifosfonicos substituidos. | |
| ES8301912A1 (es) | "procedimiento para la preparacion de derivados de carbaciclina". | |
| MX9300008A (es) | Nucleosidos terapeuticos. | |
| MX174093B (es) | 1,1-DIOXIDOS DE 3,4-DIHIDRO-2-ALQUIL-3-OXO-N-ARIL-2H[1] BENZOTIENO[3,2-e]-1,2-TIAZINO-4-CARBOXIAMIDA | |
| ES392525A1 (es) | Procedimiento para tenir fibras de poliamida sintetica o natural. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 285837 Country of ref document: ES |