ES2154262T3 - Uso de compuestos macrolidos para enfermedades oculares. - Google Patents
Uso de compuestos macrolidos para enfermedades oculares.Info
- Publication number
- ES2154262T3 ES2154262T3 ES92909558T ES92909558T ES2154262T3 ES 2154262 T3 ES2154262 T3 ES 2154262T3 ES 92909558 T ES92909558 T ES 92909558T ES 92909558 T ES92909558 T ES 92909558T ES 2154262 T3 ES2154262 T3 ES 2154262T3
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- eye diseases
- macrolid
- macrolid compounds
- prevention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 208000030533 eye disease Diseases 0.000 title abstract 2
- 206010010744 Conjunctivitis allergic Diseases 0.000 abstract 1
- 208000002205 allergic conjunctivitis Diseases 0.000 abstract 1
- 208000024998 atopic conjunctivitis Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
Abstract
SE SUMINISTRAN COMPUESTOS MACROLIDOS TALES COMO EL FR-900506 Y LOS COMPUESTOS RELACIONADOS PARA LA PREVENCION AL TRATAMIENTO DE ENFERMEDADES DEL OJO, PARTICULARMENTE CONJUNTIVITIS ALERGICAS. TAMBIEN SE PRESENTA UNA COMPOSICION QUE CONTIENE TALES COMPUESTOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919109060A GB9109060D0 (en) | 1991-04-26 | 1991-04-26 | New use |
GB919121661A GB9121661D0 (en) | 1991-10-11 | 1991-10-11 | New use |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2154262T3 true ES2154262T3 (es) | 2001-04-01 |
Family
ID=26298796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92909558T Expired - Lifetime ES2154262T3 (es) | 1991-04-26 | 1992-04-24 | Uso de compuestos macrolidos para enfermedades oculares. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5514686A (es) |
EP (1) | EP0581959B1 (es) |
JP (1) | JP3158437B2 (es) |
KR (1) | KR100237715B1 (es) |
AT (1) | ATE198708T1 (es) |
CA (1) | CA2102241C (es) |
DE (1) | DE69231644T2 (es) |
DK (1) | DK0581959T3 (es) |
ES (1) | ES2154262T3 (es) |
GR (1) | GR3035269T3 (es) |
WO (1) | WO1992019278A1 (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2736550B1 (fr) * | 1995-07-14 | 1998-07-24 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule |
PT1056454E (pt) * | 1998-02-23 | 2003-08-29 | Fujisawa Pharmaceutical Co | Utilizacao de compostos macrolido para o tratamento do glaucoma |
US6218423B1 (en) | 1998-08-14 | 2001-04-17 | Gpi Nil Holdings, Inc. | Pyrrolidine derivatives for vision and memory disorders |
US6399648B1 (en) | 1998-08-14 | 2002-06-04 | Gpi Nil Holdings, Inc. | N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders |
US6384056B1 (en) | 1998-08-14 | 2002-05-07 | Gpi Nil Holdings, Inc. | Heterocyclic thioesters or ketones for vision and memory disorders |
US6339101B1 (en) | 1998-08-14 | 2002-01-15 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders |
US6333340B1 (en) | 1998-08-14 | 2001-12-25 | Gpi Nil Holdings, Inc. | Small molecule sulfonamides for vision and memory disorders |
US6506788B1 (en) | 1998-08-14 | 2003-01-14 | Gpi Nil Holdings, Inc. | N-linked urea or carbamate of heterocyclic thioesters for vision and memory disorders |
US6376517B1 (en) * | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
US6335348B1 (en) | 1998-08-14 | 2002-01-01 | Gpi Nil Holdings, Inc. | Nitrogen-containing linear and azepinyl/ compositions and uses for vision and memory disorders |
US6337340B1 (en) | 1998-08-14 | 2002-01-08 | Gpi Nil Holdings, Inc. | Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders |
US7338976B1 (en) * | 1998-08-14 | 2008-03-04 | Gpi Nil Holdings, Inc. | Heterocyclic esters or amides for vision and memory disorders |
US7410995B1 (en) | 1998-08-14 | 2008-08-12 | Gpi Nil Holdings Inc. | N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders |
US7265150B1 (en) | 1998-08-14 | 2007-09-04 | Gpi Nil Holdings Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders |
CZ20013769A3 (cs) * | 1999-04-30 | 2002-03-13 | Sucampo Ag | Činidlo pro léčbu suchého oka |
AR033151A1 (es) * | 2001-04-12 | 2003-12-03 | Sucampo Pharmaceuticals Inc | Agente para el tratamiento oftalmico topico de las enfermedades inflamatorias oculares |
WO2003004098A1 (en) | 2001-07-06 | 2003-01-16 | Sucampo Ag | Composition for topical administration comprising an interleukin-2 inhibitor and an antimicrobial agent |
MXPA04004757A (es) * | 2001-11-19 | 2004-08-02 | Novartis Ag | Uso de una ascomicina para el tratamiento de blefaritis. |
WO2003043650A1 (en) * | 2001-11-21 | 2003-05-30 | Sucampo Ag | Use of fk506 and analogues for treating allergic diseases |
EP1536793A1 (en) * | 2002-08-09 | 2005-06-08 | Sucampo Pharmaceuticals, Inc. | Pharmaceutical compositions comprising fk506 derivatives and the ir use for the treatment of allergic diseases |
WO2004027027A2 (en) * | 2002-09-18 | 2004-04-01 | Trustees Of The University Of Pennsylvania | Method of inhibiting choroidal neovascularization |
WO2004062669A1 (en) * | 2003-01-16 | 2004-07-29 | Sucampo Ag | Use of a macrolide compound for treating dry eye |
JP2007505932A (ja) * | 2003-09-18 | 2007-03-15 | マクサイト, インコーポレイテッド | 経強膜送達 |
JP2008530127A (ja) | 2005-02-09 | 2008-08-07 | マクサイト, インコーポレイテッド | 眼の処置のための処方物 |
US8663639B2 (en) * | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
AU2007212271B2 (en) | 2006-02-09 | 2012-11-01 | Santen Pharmaceutical Co., Ltd. | Stable formulations, and methods of their preparation and use |
WO2007112052A2 (en) * | 2006-03-23 | 2007-10-04 | Macusight, Inc. | Formulations and methods for vascular permeability-related diseases or conditions |
WO2008127746A1 (en) | 2007-01-10 | 2008-10-23 | Board Of Regents The University Of Texas System | Enhanced delivery of immunosuppressive drug compositions for pulmonary delivery |
US20080265343A1 (en) * | 2007-04-26 | 2008-10-30 | International Business Machines Corporation | Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof |
WO2019060696A1 (en) | 2017-09-25 | 2019-03-28 | Surface Pharmaceuticals, Inc. | OPTHALMIC PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR SURFACE DISEASE |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4894366A (en) * | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
GB8616089D0 (en) * | 1986-07-02 | 1986-08-06 | Univ Manchester | Organic compounds |
AU630866B2 (en) * | 1987-12-09 | 1992-11-12 | Fisons Plc | Macrocyclic compounds |
EP0356399A3 (en) * | 1988-08-26 | 1991-03-20 | Sandoz Ag | Substituted 4-azatricyclo (22.3.1.04.9) octacos-18-ene derivatives, their preparation and pharmaceutical compositions containing them |
DE3906214A1 (de) * | 1989-02-28 | 1990-08-30 | Boehringer Mannheim Gmbh | Verwendung von macrolactone als antiallergica |
AU5187990A (en) * | 1989-03-02 | 1990-09-26 | Ensoniq Corporation | Apparatus and a method for fitting a hearing aid |
IE64214B1 (en) * | 1989-06-06 | 1995-07-26 | Fujisawa Pharmaceutical Co | Macrolides for the treatment of reversible obstructive airways diseases |
US5100899A (en) * | 1989-06-06 | 1992-03-31 | Roy Calne | Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof |
WO1990015805A1 (en) * | 1989-06-14 | 1990-12-27 | Sandoz Ltd | Heteroatoms-containing tricyclic compounds |
AU635286B2 (en) * | 1989-07-05 | 1993-03-18 | Astellas Pharma Inc. | Aqueous liquid composition for external use |
ZA924953B (en) * | 1991-07-25 | 1993-04-28 | Univ Louisville Res Found | Method of treating ocular inflammation |
-
1992
- 1992-04-24 CA CA002102241A patent/CA2102241C/en not_active Expired - Lifetime
- 1992-04-24 EP EP92909558A patent/EP0581959B1/en not_active Expired - Lifetime
- 1992-04-24 WO PCT/JP1992/000545 patent/WO1992019278A1/en active IP Right Grant
- 1992-04-24 DE DE69231644T patent/DE69231644T2/de not_active Expired - Lifetime
- 1992-04-24 AT AT92909558T patent/ATE198708T1/de active
- 1992-04-24 ES ES92909558T patent/ES2154262T3/es not_active Expired - Lifetime
- 1992-04-24 JP JP50869892A patent/JP3158437B2/ja not_active Expired - Lifetime
- 1992-04-24 US US08/133,194 patent/US5514686A/en not_active Expired - Lifetime
- 1992-04-24 KR KR1019930703221A patent/KR100237715B1/ko not_active IP Right Cessation
- 1992-04-24 DK DK92909558T patent/DK0581959T3/da active
-
2001
- 2001-01-18 GR GR20000402818T patent/GR3035269T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH07500570A (ja) | 1995-01-19 |
EP0581959B1 (en) | 2001-01-17 |
GR3035269T3 (en) | 2001-04-30 |
EP0581959A1 (en) | 1994-02-09 |
US5514686A (en) | 1996-05-07 |
KR100237715B1 (ko) | 2000-02-01 |
DE69231644D1 (de) | 2001-02-22 |
JP3158437B2 (ja) | 2001-04-23 |
WO1992019278A1 (en) | 1992-11-12 |
KR940701264A (ko) | 1994-05-28 |
ATE198708T1 (de) | 2001-02-15 |
CA2102241C (en) | 2003-12-30 |
DE69231644T2 (de) | 2001-05-23 |
DK0581959T3 (da) | 2001-01-29 |
CA2102241A1 (en) | 1992-10-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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