ES2049186B1 - Procedimiento para la preparacion de nuevos derivados de benzofuranil-imidazol. - Google Patents

Procedimiento para la preparacion de nuevos derivados de benzofuranil-imidazol.

Info

Publication number
ES2049186B1
ES2049186B1 ES09202615A ES9202615A ES2049186B1 ES 2049186 B1 ES2049186 B1 ES 2049186B1 ES 09202615 A ES09202615 A ES 09202615A ES 9202615 A ES9202615 A ES 9202615A ES 2049186 B1 ES2049186 B1 ES 2049186B1
Authority
ES
Spain
Prior art keywords
procedure
preparation
new derivatives
benzofuranil
imidazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES09202615A
Other languages
English (en)
Spanish (es)
Other versions
ES2049186A1 (es
Inventor
Sevilla Jesus Andres Garcia
Martinez Jose Javier Meana
Fernandez Fernando Barturen
Caballero Fernando A Geijo
Banos Angel Menargues
Vidal Rosendo Obach
Rodas Francesc Pla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of ES2049186A1 publication Critical patent/ES2049186A1/es
Application granted granted Critical
Publication of ES2049186B1 publication Critical patent/ES2049186B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES09202615A 1991-12-27 1992-12-24 Procedimiento para la preparacion de nuevos derivados de benzofuranil-imidazol. Expired - Fee Related ES2049186B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919127430A GB9127430D0 (en) 1991-12-27 1991-12-27 Benzofuranylimidazole derivatives

Publications (2)

Publication Number Publication Date
ES2049186A1 ES2049186A1 (es) 1994-04-01
ES2049186B1 true ES2049186B1 (es) 1994-12-16

Family

ID=10706855

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09202615A Expired - Fee Related ES2049186B1 (es) 1991-12-27 1992-12-24 Procedimiento para la preparacion de nuevos derivados de benzofuranil-imidazol.

Country Status (34)

Country Link
US (2) US5310930A (enExample)
JP (1) JPH05271223A (enExample)
AT (1) AT402071B (enExample)
AU (1) AU652877B2 (enExample)
BE (1) BE1006226A3 (enExample)
CA (1) CA2086137C (enExample)
CH (1) CH685344A5 (enExample)
DE (1) DE4244342C2 (enExample)
DK (1) DK155692A (enExample)
DZ (1) DZ1655A1 (enExample)
ES (1) ES2049186B1 (enExample)
FI (1) FI111365B (enExample)
FR (2) FR2685698B1 (enExample)
GB (2) GB9127430D0 (enExample)
GR (1) GR1001566B (enExample)
HK (1) HK27096A (enExample)
HU (1) HUT67269A (enExample)
IE (1) IE73489B1 (enExample)
IN (1) IN180496B (enExample)
IT (1) IT1256238B (enExample)
LU (1) LU88204A1 (enExample)
MA (1) MA22752A1 (enExample)
MY (1) MY109729A (enExample)
NL (1) NL9202238A (enExample)
NO (1) NO300841B1 (enExample)
NZ (1) NZ245500A (enExample)
OA (1) OA09903A (enExample)
PL (3) PL170404B1 (enExample)
PT (1) PT101158B (enExample)
RU (1) RU2068416C1 (enExample)
SE (1) SE503224C2 (enExample)
TN (1) TNSN92118A1 (enExample)
TW (1) TW226997B (enExample)
ZA (1) ZA929736B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
ES2198033T3 (es) * 1997-12-19 2004-01-16 Eli Lilly And Company Compuestos de imidazolina hipoglucemicos.
EP1266897A3 (en) * 1997-12-19 2003-12-03 Eli Lilly And Company Hypoglycemic imidazoline compounds
GB2351082A (en) * 1999-06-18 2000-12-20 Lilly Forschung Gmbh Synthesis of Cyclic Substituted Amidines
CA2512280A1 (en) * 2003-03-07 2004-09-16 Kowa Co., Ltd. Benzofuran derivative

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH593967A5 (en) * 1971-11-09 1977-12-30 Ciba Geigy Ag Optical brighteners for organic materials - consist of quaternised benzofuranyl or naphthofuranyl benzimidazole cpds.
US3927023A (en) * 1974-05-24 1975-12-16 Warner Lambert Co Imidazolyl benzofurans
ZW13782A1 (en) * 1981-07-28 1982-10-06 Reckitt & Colmann Prod Ltd Imidazoline derivatives
GB2122987B (en) * 1982-06-01 1985-09-25 Zyma Sa (+)-cyanidan-3-ol derivatives and pharmaceutical preparations thereof
ES523609A0 (es) * 1982-07-05 1985-03-01 Erba Farmitalia Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos.
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use
GB8720693D0 (en) * 1987-09-03 1987-10-07 Glaxo Group Ltd Chemical compounds
GB8805628D0 (en) * 1988-03-09 1988-04-07 Erba Farmitalia Hypolipidaemic imidazol-2-yl-derivatives of bicyclic compounds & process for their preparation

Also Published As

Publication number Publication date
US5310930A (en) 1994-05-10
IE922945A1 (en) 1993-06-30
ITMI922954A0 (it) 1992-12-23
GB2262739A (en) 1993-06-30
CA2086137A1 (en) 1993-06-28
PT101158A (pt) 1994-03-31
NZ245500A (en) 1994-09-27
RU2068416C1 (ru) 1996-10-27
SE9203824L (sv) 1993-06-28
GB2262739B (en) 1995-05-17
ZA929736B (en) 1993-06-14
PL170205B1 (pl) 1996-11-29
IE73489B1 (en) 1997-06-04
FI925755A0 (fi) 1992-12-18
LU88204A1 (fr) 1993-05-17
FR2685637A1 (fr) 1993-07-02
SE9203824D0 (sv) 1992-12-18
GR1001566B (el) 1994-05-31
ATA252892A (de) 1996-06-15
US5354769A (en) 1994-10-11
NO925007L (no) 1993-06-28
GB9127430D0 (en) 1992-02-19
FR2685637B1 (fr) 1994-03-25
DK155692A (da) 1993-06-28
AU652877B2 (en) 1994-09-08
FI925755L (fi) 1993-06-28
NL9202238A (nl) 1993-07-16
HK27096A (en) 1996-02-23
PL297109A1 (en) 1993-09-06
MA22752A1 (fr) 1993-07-01
TNSN92118A1 (fr) 1993-06-08
TW226997B (enExample) 1994-07-21
CA2086137C (en) 2005-09-06
HUT67269A (en) 1995-03-28
NO300841B1 (no) 1997-08-04
PL170404B1 (pl) 1996-12-31
FI111365B (fi) 2003-07-15
DK155692D0 (da) 1992-12-23
IN180496B (enExample) 1998-02-07
ES2049186A1 (es) 1994-04-01
AT402071B (de) 1997-01-27
NO925007D0 (no) 1992-12-23
ITMI922954A1 (it) 1994-06-23
PT101158B (pt) 1999-09-30
MY109729A (en) 1997-05-31
GB9226997D0 (en) 1993-02-17
SE503224C2 (sv) 1996-04-22
DE4244342A1 (enExample) 1993-07-01
FR2685698B1 (fr) 1994-03-11
AU3049692A (en) 1993-07-01
DZ1655A1 (fr) 2002-02-17
IT1256238B (it) 1995-11-29
DE4244342C2 (de) 2001-04-19
CH685344A5 (fr) 1995-06-15
JPH05271223A (ja) 1993-10-19
OA09903A (fr) 1994-09-15
FR2685698A1 (fr) 1993-07-02
BE1006226A3 (fr) 1994-06-14
PL170409B1 (pl) 1996-12-31

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Effective date: 20180806