ES2038224T3 - Derivados de acido n-acetil-3-fluoro-neuraminico y su preparacion. - Google Patents

Derivados de acido n-acetil-3-fluoro-neuraminico y su preparacion.

Info

Publication number
ES2038224T3
ES2038224T3 ES198888103065T ES88103065T ES2038224T3 ES 2038224 T3 ES2038224 T3 ES 2038224T3 ES 198888103065 T ES198888103065 T ES 198888103065T ES 88103065 T ES88103065 T ES 88103065T ES 2038224 T3 ES2038224 T3 ES 2038224T3
Authority
ES
Spain
Prior art keywords
derivatives
fluoro
preparation
acid
neuraminico
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888103065T
Other languages
English (en)
Inventor
Hiroshi Ohrui
Hiroshi Meguro
Tatsuo Ido
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mect Corp
Original Assignee
Mect Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mect Corp filed Critical Mect Corp
Application granted granted Critical
Publication of ES2038224T3 publication Critical patent/ES2038224T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pyrane Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A NUEVOS DERIVADOS DEL ACIDO N-ACETIL-3-FLUORONEURAMINICO Y A SU PREPARACION. EL CITADO ACIDO SE PUEDE SINTETIZAR POR REACCION DE UNA SOLUCION DE ALQUIL-5ACETAMIDO-2,6-ANHIDRO-4,7,8,9-TETRA-O-ACETIL-2,3,5-TRIDESOXI-DGLICERO-D-GALACTO-2-ENONATO CON: A) UNA GAS INERTE QUE CONTIENE FLUOR, O B) ACETIL-HIPOFLUORITO OBTENIDO PASANDO EL GAS INERTE QUE CONTIENE FLUOR A TRAVES DE UNA MEZCLA DE ACIDO ACETICO/ ACETATO, POR LA QUE SE PASAN LA SOLUCION Y SEPERANDO DESPUES EL DOSILVENTE Y SOMETIENDO EL RESIDUO A CROMATOGRAFIA EN COLUMNA DE GEL DE SILICE.
ES198888103065T 1987-03-06 1988-03-01 Derivados de acido n-acetil-3-fluoro-neuraminico y su preparacion. Expired - Lifetime ES2038224T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62052358A JP2573594B2 (ja) 1987-03-06 1987-03-06 Ｎーアセチルー３ーフルオローノイラミン酸誘導体およびその製造方法

Publications (1)

Publication Number Publication Date
ES2038224T3 true ES2038224T3 (es) 1993-07-16

Family

ID=12912583

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888103065T Expired - Lifetime ES2038224T3 (es) 1987-03-06 1988-03-01 Derivados de acido n-acetil-3-fluoro-neuraminico y su preparacion.

Country Status (15)

Country Link
EP (1) EP0281067B1 (es)
JP (1) JP2573594B2 (es)
KR (1) KR960011581B1 (es)
CN (1) CN88101146A (es)
AT (1) ATE75479T1 (es)
AU (1) AU601552B2 (es)
CA (1) CA1314877C (es)
DE (1) DE3870485D1 (es)
DK (1) DK106888A (es)
ES (1) ES2038224T3 (es)
FI (1) FI881032A (es)
HU (1) HU200466B (es)
IL (1) IL85635A (es)
NO (1) NO168588C (es)
NZ (1) NZ223681A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01287029A (ja) * 1988-05-13 1989-11-17 Mect Corp 新規抗ウィルス剤
CN1065241C (zh) * 1994-05-27 2001-05-02 大金工业株式会社 在7位上用氟取代的2,3－二脱氢唾液酸及其合成中间体
EP0882721A4 (en) * 1996-09-10 1999-12-22 Daikin Ind Ltd 4-SUBSTITUTED 2,7-DIDEOXY-7-FLUORO-2,3-DIDEHYDRO SIAL ACIDS
JP6302909B2 (ja) * 2012-08-18 2018-03-28 アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ シアリダーゼの同定および画像化のための細胞透過性プローブ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3219209A1 (de) * 1981-05-22 1982-12-09 Kanto Ishi Pharmaceutical Co., Ltd., Tokyo N-acetylneuraminsaeure-derivate
JPS6168418A (ja) * 1984-09-11 1986-04-08 Kanto Ishi Pharma Co Ltd 去痰薬

Also Published As

Publication number Publication date
NO880971D0 (no) 1988-03-04
EP0281067A3 (en) 1988-12-14
NZ223681A (en) 1989-10-27
FI881032A (fi) 1988-09-07
IL85635A (en) 1992-02-16
HU200466B (en) 1990-06-28
CN88101146A (zh) 1988-09-21
EP0281067B1 (en) 1992-04-29
ATE75479T1 (de) 1992-05-15
KR880011188A (ko) 1988-10-27
JPS63218688A (ja) 1988-09-12
AU601552B2 (en) 1990-09-13
NO168588C (no) 1992-03-11
KR960011581B1 (ko) 1996-08-24
IL85635A0 (en) 1988-08-31
EP0281067A2 (en) 1988-09-07
NO880971L (no) 1988-09-07
DK106888A (da) 1988-09-07
CA1314877C (en) 1993-03-23
DK106888D0 (da) 1988-02-29
NO168588B (no) 1991-12-02
AU1268988A (en) 1988-09-08
FI881032A0 (fi) 1988-03-04
DE3870485D1 (de) 1992-06-04
HUT47302A (en) 1989-02-28
JP2573594B2 (ja) 1997-01-22

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