ES2038224T3 - Derivados de acido n-acetil-3-fluoro-neuraminico y su preparacion. - Google Patents
Derivados de acido n-acetil-3-fluoro-neuraminico y su preparacion.Info
- Publication number
- ES2038224T3 ES2038224T3 ES198888103065T ES88103065T ES2038224T3 ES 2038224 T3 ES2038224 T3 ES 2038224T3 ES 198888103065 T ES198888103065 T ES 198888103065T ES 88103065 T ES88103065 T ES 88103065T ES 2038224 T3 ES2038224 T3 ES 2038224T3
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- fluoro
- preparation
- acid
- neuraminico
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pyrane Compounds (AREA)
Abstract
LA INVENCION SE REFIERE A NUEVOS DERIVADOS DEL ACIDO N-ACETIL-3-FLUORONEURAMINICO Y A SU PREPARACION. EL CITADO ACIDO SE PUEDE SINTETIZAR POR REACCION DE UNA SOLUCION DE ALQUIL-5ACETAMIDO-2,6-ANHIDRO-4,7,8,9-TETRA-O-ACETIL-2,3,5-TRIDESOXI-DGLICERO-D-GALACTO-2-ENONATO CON: A) UNA GAS INERTE QUE CONTIENE FLUOR, O B) ACETIL-HIPOFLUORITO OBTENIDO PASANDO EL GAS INERTE QUE CONTIENE FLUOR A TRAVES DE UNA MEZCLA DE ACIDO ACETICO/ ACETATO, POR LA QUE SE PASAN LA SOLUCION Y SEPERANDO DESPUES EL DOSILVENTE Y SOMETIENDO EL RESIDUO A CROMATOGRAFIA EN COLUMNA DE GEL DE SILICE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62052358A JP2573594B2 (ja) | 1987-03-06 | 1987-03-06 | Nーアセチルー3ーフルオローノイラミン酸誘導体およびその製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2038224T3 true ES2038224T3 (es) | 1993-07-16 |
Family
ID=12912583
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198888103065T Expired - Lifetime ES2038224T3 (es) | 1987-03-06 | 1988-03-01 | Derivados de acido n-acetil-3-fluoro-neuraminico y su preparacion. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0281067B1 (es) |
JP (1) | JP2573594B2 (es) |
KR (1) | KR960011581B1 (es) |
CN (1) | CN88101146A (es) |
AT (1) | ATE75479T1 (es) |
AU (1) | AU601552B2 (es) |
CA (1) | CA1314877C (es) |
DE (1) | DE3870485D1 (es) |
DK (1) | DK106888A (es) |
ES (1) | ES2038224T3 (es) |
FI (1) | FI881032A (es) |
HU (1) | HU200466B (es) |
IL (1) | IL85635A (es) |
NO (1) | NO168588C (es) |
NZ (1) | NZ223681A (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01287029A (ja) * | 1988-05-13 | 1989-11-17 | Mect Corp | 新規抗ウィルス剤 |
CN1065241C (zh) * | 1994-05-27 | 2001-05-02 | 大金工业株式会社 | 在7位上用氟取代的2,3-二脱氢唾液酸及其合成中间体 |
EP0882721A4 (en) * | 1996-09-10 | 1999-12-22 | Daikin Ind Ltd | 4-SUBSTITUTED 2,7-DIDEOXY-7-FLUORO-2,3-DIDEHYDRO SIAL ACIDS |
JP6302909B2 (ja) * | 2012-08-18 | 2018-03-28 | アカデミア シニカAcademia Sinica | シアリダーゼの同定および画像化のための細胞透過性プローブ |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3219209A1 (de) * | 1981-05-22 | 1982-12-09 | Kanto Ishi Pharmaceutical Co., Ltd., Tokyo | N-acetylneuraminsaeure-derivate |
JPS6168418A (ja) * | 1984-09-11 | 1986-04-08 | Kanto Ishi Pharma Co Ltd | 去痰薬 |
-
1987
- 1987-03-06 JP JP62052358A patent/JP2573594B2/ja not_active Expired - Lifetime
-
1988
- 1988-02-29 DK DK106888A patent/DK106888A/da unknown
- 1988-02-29 NZ NZ223681A patent/NZ223681A/xx unknown
- 1988-03-01 EP EP88103065A patent/EP0281067B1/en not_active Expired - Lifetime
- 1988-03-01 ES ES198888103065T patent/ES2038224T3/es not_active Expired - Lifetime
- 1988-03-01 DE DE8888103065T patent/DE3870485D1/de not_active Expired - Fee Related
- 1988-03-01 AT AT88103065T patent/ATE75479T1/de active
- 1988-03-02 CA CA000560354A patent/CA1314877C/en not_active Expired - Fee Related
- 1988-03-03 IL IL85635A patent/IL85635A/xx not_active IP Right Cessation
- 1988-03-04 AU AU12689/88A patent/AU601552B2/en not_active Ceased
- 1988-03-04 NO NO880971A patent/NO168588C/no unknown
- 1988-03-04 FI FI881032A patent/FI881032A/fi not_active Application Discontinuation
- 1988-03-05 KR KR1019880002285A patent/KR960011581B1/ko not_active IP Right Cessation
- 1988-03-06 CN CN198888101146A patent/CN88101146A/zh active Pending
- 1988-03-07 HU HU881105A patent/HU200466B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO880971D0 (no) | 1988-03-04 |
EP0281067A3 (en) | 1988-12-14 |
NZ223681A (en) | 1989-10-27 |
FI881032A (fi) | 1988-09-07 |
IL85635A (en) | 1992-02-16 |
HU200466B (en) | 1990-06-28 |
CN88101146A (zh) | 1988-09-21 |
EP0281067B1 (en) | 1992-04-29 |
ATE75479T1 (de) | 1992-05-15 |
KR880011188A (ko) | 1988-10-27 |
JPS63218688A (ja) | 1988-09-12 |
AU601552B2 (en) | 1990-09-13 |
NO168588C (no) | 1992-03-11 |
KR960011581B1 (ko) | 1996-08-24 |
IL85635A0 (en) | 1988-08-31 |
EP0281067A2 (en) | 1988-09-07 |
NO880971L (no) | 1988-09-07 |
DK106888A (da) | 1988-09-07 |
CA1314877C (en) | 1993-03-23 |
DK106888D0 (da) | 1988-02-29 |
NO168588B (no) | 1991-12-02 |
AU1268988A (en) | 1988-09-08 |
FI881032A0 (fi) | 1988-03-04 |
DE3870485D1 (de) | 1992-06-04 |
HUT47302A (en) | 1989-02-28 |
JP2573594B2 (ja) | 1997-01-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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