ES2032381T3 - Un compuesto quimico. (reserva del art. 167.2 cpe). - Google Patents

Un compuesto quimico. (reserva del art. 167.2 cpe).

Info

Publication number
ES2032381T3
ES2032381T3 ES198686202230T ES86202230T ES2032381T3 ES 2032381 T3 ES2032381 T3 ES 2032381T3 ES 198686202230 T ES198686202230 T ES 198686202230T ES 86202230 T ES86202230 T ES 86202230T ES 2032381 T3 ES2032381 T3 ES 2032381T3
Authority
ES
Spain
Prior art keywords
cpe
reservation
art
compounds
chemical compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686202230T
Other languages
English (en)
Spanish (es)
Inventor
Jan Heeres
Leo Jacobus Jozef Backx
Jozef Bertha August Thijssen
Alfonsus Guilielms Knaeps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of ES2032381T3 publication Critical patent/ES2032381T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES198686202230T 1985-12-23 1986-12-10 Un compuesto quimico. (reserva del art. 167.2 cpe). Expired - Lifetime ES2032381T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81267085A 1985-12-23 1985-12-23

Publications (1)

Publication Number Publication Date
ES2032381T3 true ES2032381T3 (es) 1993-02-16

Family

ID=25210297

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198686202230T Expired - Lifetime ES2032381T3 (es) 1985-12-23 1986-12-10 Un compuesto quimico. (reserva del art. 167.2 cpe).

Country Status (18)

Country Link
EP (1) EP0228125B1 (en, 2012)
JP (2) JPH0749428B2 (en, 2012)
AT (1) ATE73799T1 (en, 2012)
AU (2) AU589726B2 (en, 2012)
CA (1) CA1292472C (en, 2012)
CY (1) CY1825A (en, 2012)
DE (1) DE3684431D1 (en, 2012)
DK (2) DK164167C (en, 2012)
ES (1) ES2032381T3 (en, 2012)
FI (1) FI88505C (en, 2012)
GR (1) GR3004114T3 (en, 2012)
HK (1) HK46295A (en, 2012)
IE (1) IE59564B1 (en, 2012)
IL (1) IL81054A (en, 2012)
NO (1) NO167917C (en, 2012)
NZ (1) NZ218553A (en, 2012)
PT (1) PT84007B (en, 2012)
ZA (1) ZA869637B (en, 2012)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ223799A (en) * 1987-03-25 1989-12-21 Janssen Pharmaceutica Nv Azolylmethyl-dioxolanylmethoxyphenyl-piperazinyl-phenyl-triazolones and antimicrobial compositions
CA1331757C (en) 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
GR1000330B (el) * 1988-07-01 1992-06-25 Janssen Pharmaceutica Nv Μεθοδος παρασκευης παραγωγων 2,4 διυδρο-3η-1,2,4-τριαζολ-3-ονης.
GR1000297B (el) * 1988-07-01 1992-05-12 Janssen Pharmaceutica Nv Μεθοδος παρασκευης παραγωγων 2,4-διυδρο-3η-1,2,4-τριαζολ-3-ονης.
GR1000302B (el) * 1988-07-01 1992-05-12 Janssen Pharmaceutica Nv Μεθοδος παρασκευης παραγωγων 2,4-διυδρο-3η-1,2,4-τριαζολ-3-ονης.
GR1000298B (el) * 1988-07-01 1992-05-12 Janssen Pharmaceutica Nv Μεθοδος παρασκευης παραγωγων 2,4-διυδρο-3η-1,2,4-τριαζολ-3-ονης.
GB8903592D0 (en) * 1989-02-16 1989-04-05 Boots Co Plc Therapeutic agents
NZ233502A (en) * 1989-06-09 1991-11-26 Janssen Pharmaceutica Nv 4-(1,2,4-triazole- or imidazole-phenyl-substituted) -1-(1,3-dioxolan-4-ylmethoxyphenyl) piperazine derivatives; preparatory processes: fungicidal and antiviral compositions
CA2076257A1 (en) * 1991-09-13 1993-03-14 Jan Heeres 4-¬4-¬4-(4-hydroxyphenyl)-1- piperazinyl|phenyl|-5-methyl-3h -1,2,4-triazol-3-one derivatives
TW279864B (en, 2012) * 1993-02-19 1996-07-01 Janssen Pharmaceutica Nv
EP0736030B1 (en) * 1993-12-21 2001-08-29 Schering Corporation Tetrahydrofuran antifungals
SK282059B6 (sk) * 1994-01-24 2001-10-08 Janssen Pharmaceutica N. V. Azoly, spôsob ich výroby a farmaceutické prostriedky na ich báze
US5571811A (en) * 1994-07-12 1996-11-05 Janssen Pharmaceutica N.V. Sulfonamide derivatives of azolones
WO1996013499A1 (en) * 1994-10-27 1996-05-09 Janssen Pharmaceutica N.V. Apolipoprotein-b synthesis inhibitors
US5625064A (en) * 1995-04-19 1997-04-29 Schering Corporation Process for the preparation of triazolones
TW457240B (en) * 1995-04-20 2001-10-01 Janssen Pharmaceutica Nv Novel triazolones as apolipoprotein-B synthesis inhibitors
WO1997000248A1 (en) * 1995-06-19 1997-01-03 Schering Corporation Hydroxyalkyl-substituted triazolones antifungals
AU773405B2 (en) * 1996-11-12 2004-05-27 Sepracor, Inc. Hydroxyitraconazole enantiomer mixtures
CN1237172A (zh) * 1996-11-12 1999-12-01 塞普拉科公司 2r,4s,r,s－和2s,4r,r,s－羟基伊曲康唑－和羟基沙波康唑衍生物
UA63954C2 (en) * 1997-07-11 2004-02-16 Janssen Pharmaceutica Nv (+/-) norcisapride, a process for the preparation thereof, intermediate compounds, composition based thereon for use in the manufacture of medicaments for treating gastro-intestinal disorders
TW593312B (en) * 1997-07-11 2004-06-21 Janssen Pharmaceutica Nv 2,4,4-trisubstituted-1,3-dioxolane antifungals
AU9592998A (en) * 1997-10-07 1999-04-27 Schering Corporation Crystalline antifungal glycine ester polymorph
CN1349540A (zh) * 1999-05-04 2002-05-15 詹森药业有限公司 抗真菌的醚类
KR100342383B1 (ko) * 1999-06-17 2002-12-06 한국화학연구원 이소옥사졸리딘 유도체, 그의 제조 방법 및 그를 포함하는 살균제 조성물
RU2585760C2 (ru) * 2010-05-19 2016-06-10 Сандоз Аг Способ получения хиральных триазолонов
ES2790875T3 (es) 2014-12-05 2020-10-29 Pulmocide Ltd Compuesto antimicótico
EP3298006B1 (en) 2015-05-21 2020-01-01 Pulmocide Limited Antifungal 4-(4-(4-(((3r,5r)-5-((1 h -1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl )-n -(2-hydroxycyclohexyl)benzamide, or a pharmaceutically acceptable salt thereof.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144346A (en) * 1977-01-31 1979-03-13 Janssen Pharmaceutica N.V. Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles
US4267179A (en) * 1978-06-23 1981-05-12 Janssen Pharmaceutica, N.V. Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
US4619931A (en) * 1983-02-28 1986-10-28 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles

Also Published As

Publication number Publication date
AU589726B2 (en) 1989-10-19
DK164167C (da) 1992-10-12
IL81054A0 (en) 1987-03-31
NZ218553A (en) 1990-06-26
GR3004114T3 (en, 2012) 1993-03-31
FI88505C (fi) 1993-05-25
DK74691D0 (da) 1991-04-23
DE3684431D1 (de) 1992-04-23
ATE73799T1 (de) 1992-04-15
NO865235L (no) 1987-06-24
DK167356B1 (da) 1993-10-18
DK625586D0 (da) 1986-12-22
HK46295A (en) 1995-04-07
PT84007B (pt) 1989-06-30
JPH0749428B2 (ja) 1995-05-31
ZA869637B (en) 1988-08-31
NO167917B (no) 1991-09-16
NO865235D0 (no) 1986-12-22
IL81054A (en) 1992-03-29
JP2574656B2 (ja) 1997-01-22
AU6685386A (en) 1987-06-25
EP0228125A1 (en) 1987-07-08
FI865257A0 (fi) 1986-12-22
PT84007A (en) 1987-01-01
CA1292472C (en) 1991-11-26
CY1825A (en) 1995-12-01
EP0228125B1 (en) 1992-03-18
AU593736B2 (en) 1990-02-15
AU1607688A (en) 1988-08-04
JPH07285963A (ja) 1995-10-31
FI88505B (fi) 1993-02-15
NO167917C (no) 1991-12-27
IE863369L (en) 1987-06-23
IE59564B1 (en) 1994-03-09
DK164167B (da) 1992-05-18
FI865257A7 (fi) 1987-06-24
DK74691A (da) 1991-04-23
DK625586A (da) 1987-06-24
JPS62158275A (ja) 1987-07-14

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