ES2005158A6 - Procedimiento de preparar derivados sulfonamidicos - Google Patents

Procedimiento de preparar derivados sulfonamidicos

Info

Publication number
ES2005158A6
ES2005158A6 ES8701081A ES8701081A ES2005158A6 ES 2005158 A6 ES2005158 A6 ES 2005158A6 ES 8701081 A ES8701081 A ES 8701081A ES 8701081 A ES8701081 A ES 8701081A ES 2005158 A6 ES2005158 A6 ES 2005158A6
Authority
ES
Spain
Prior art keywords
radical
denotes
alkyl
sulphinyl
sulphonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8701081A
Other languages
English (en)
Inventor
Constansa Jordi Frigola
Pinol Augusto Colombo
Corominas Juan Pares
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Publication of ES2005158A6 publication Critical patent/ES2005158A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

Abstract

PROCEDIMIENTO DE PREPARAR DERIVADOS SULFONAMIDICOS, PARTICULARMENTE DE LA FORMULA GENERAL I, EN EL CUAL SE HACE REACCIONAR UN COMPUESTO DE FORMULA GENERAL IIEN SUSPENSION EN AGUA O EN ACIDO ACETICO, CON UNA CORRIENTE DE CLORO GASEOSO; SE FILTRA EL CLORURO DE ACIDO FORMADO Y SE AÑADE A UNA DISOLUCION DE UN COMPUESTO DE LA FORMULA GENERAL IIIEFECTUANDOSE LA REACCION A TEMPERATURAS COMPRENDIDAS ENTRE -10GC Y 40GC; EL SIGNIFICADO DE LOS SUSTITUYENTES DE LAS ANTERIORES FORMULAS Y OTRAS VARIANTES DEL PROCEDIMIENTO SE INDICAN EN LA DESCRIPCION.LOS NUEVOS COMPUESTOS OBTENIDOS SON ESPECIALMENTE UTILIZABLES COMO INTERMEDIOS Y PARA LA PREPARACION DE MEDICAMENTOS, DESTINADOS AL TRATAMIENTO DE ENFERMEDADES GASTROINTESTINALES.SE DESCRIBE UN PROCEDIMIENTO DE PREPARAR DERIVADOS DE BENCIMIDAZOL-2-SULFONAMIDA Y DE IMIDAZOPIRIDIN-2-SULFONAMIDA QUE TIENEN UTILIDAD EN LA FABRICACION DE MEDICAMENTOS DESTINADOS AL TRATAMIENTO DE LAS ENFERMEDADES GASTROINTESTINALES, EN PARTICULAR EN LA FABRICACION DE AGENTES INHIBIDORES DE LA SECRECION DE ACIDO GASTRICO, DE AGENTES ANTIULCEROSOS Y DE AGENTES CITOPROTECTORES.
ES8701081A 1986-04-21 1987-04-14 Procedimiento de preparar derivados sulfonamidicos Expired ES2005158A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8605721A FR2597478B1 (fr) 1986-04-21 1986-04-21 Benzimidazoles et imidazopyridines sulfonamides, leur preparation et leur application en tant que medicaments.

Publications (1)

Publication Number Publication Date
ES2005158A6 true ES2005158A6 (es) 1989-03-01

Family

ID=9334440

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8701081A Expired ES2005158A6 (es) 1986-04-21 1987-04-14 Procedimiento de preparar derivados sulfonamidicos

Country Status (20)

Country Link
US (2) US4933338A (es)
EP (1) EP0246126A1 (es)
JP (1) JPH0643404B2 (es)
KR (1) KR930003613B1 (es)
CN (1) CN87102916A (es)
AU (1) AU608511B2 (es)
BR (1) BR8701897A (es)
CA (1) CA1300133C (es)
DD (1) DD297817A5 (es)
DK (1) DK185487A (es)
ES (1) ES2005158A6 (es)
FR (1) FR2597478B1 (es)
HU (1) HUT63151A (es)
IN (1) IN167204B (es)
NO (1) NO871643L (es)
PL (1) PL156736B1 (es)
PT (1) PT84724B (es)
RU (1) RU1813087C (es)
YU (1) YU46193B (es)
ZA (1) ZA872739B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71664A (en) * 1983-05-03 1987-11-30 Byk Gulden Lomberg Chem Fab Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same
KR950001015B1 (ko) * 1986-01-10 1995-02-07 닛뽕 케미화 가부시끼가이샤 술폭시드 유도체의 제조방법
EP0374261A1 (en) * 1988-05-12 1990-06-27 Eisai Co., Ltd. Pyridinium salt and pharmacological composition containing the same
EP0694535A1 (en) 1994-04-29 1996-01-31 Eli Lilly And Company Non-peptidyl tachykinin receptor antagonists
US6479514B1 (en) 1998-05-23 2002-11-12 Altana Pharma Ag Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity
CN1295561A (zh) 1998-06-03 2001-05-16 Gpinil控股公司 N－杂环羧酸或羧酸等排物的n－结合氨磺酰
US6974815B2 (en) * 2002-10-11 2005-12-13 Bristol-Myers Squibb Company Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents
CN101497616B (zh) * 2008-01-30 2011-05-18 山东轩竹医药科技有限公司 含有氨基氧基取代的吡啶的咪唑并吡啶的化合物
CN110551145B (zh) * 2019-10-24 2022-08-05 江苏师范大学 一类呋喃并香豆素-Tröger’s Base衍生物及其合成方法与应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2603649A (en) * 1950-04-04 1952-07-15 American Cyanamid Co Heterocyclic sulfonamides and method of preparing the same
BE502319A (es) * 1950-04-04
GB833049A (en) * 1957-04-04 1960-04-21 Omikron Gagliardi Soc Di Fatto Improvements in the preparation of heterocyclic sulfonamides
DE2726625A1 (de) * 1976-06-25 1977-12-29 Ciba Geigy Ag Verfahren zum flammfestmachen von polyesterfasermaterialien
GB8316645D0 (en) * 1983-06-18 1983-07-20 Wyeth John & Brother Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
PL265299A1 (en) 1988-07-21
DK185487D0 (da) 1987-04-10
JPS62289568A (ja) 1987-12-16
CA1300133C (fr) 1992-05-05
AU608511B2 (en) 1991-04-11
CN87102916A (zh) 1988-04-27
IN167204B (es) 1990-09-22
NO871643D0 (no) 1987-04-21
DK185487A (da) 1987-10-22
EP0246126A1 (fr) 1987-11-19
US4943570A (en) 1990-07-24
FR2597478A1 (fr) 1987-10-23
KR930003613B1 (ko) 1993-05-08
FR2597478B1 (fr) 1988-12-16
PT84724B (pt) 1989-12-29
HUT63151A (en) 1993-07-28
RU1813087C (ru) 1993-04-30
NO871643L (no) 1987-10-22
YU72387A (en) 1989-02-28
JPH0643404B2 (ja) 1994-06-08
DD297817A5 (de) 1992-01-23
PL156736B1 (pl) 1992-04-30
US4933338A (en) 1990-06-12
BR8701897A (pt) 1988-02-02
PT84724A (fr) 1987-05-01
YU46193B (sh) 1993-05-28
KR870010050A (ko) 1987-11-30
ZA872739B (en) 1987-12-30
AU7143887A (en) 1987-10-22

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990201