ES2002382A6 - Un procedimiento para la preparacion de una tableta farmaceutica para administracion oral - Google Patents

Un procedimiento para la preparacion de una tableta farmaceutica para administracion oral

Info

Publication number
ES2002382A6
ES2002382A6 ES8602263A ES8602263A ES2002382A6 ES 2002382 A6 ES2002382 A6 ES 2002382A6 ES 8602263 A ES8602263 A ES 8602263A ES 8602263 A ES8602263 A ES 8602263A ES 2002382 A6 ES2002382 A6 ES 2002382A6
Authority
ES
Spain
Prior art keywords
cefuroxime axetil
dragee
film coat
film
tablet core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8602263A
Other languages
English (en)
Inventor
David Deutsch
Jamshed Anwar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10585921&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2002382(A6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES2002382A6 publication Critical patent/ES2002382A6/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UNA TABLETA FARMACEUTICA PARA ADMINISTRACION ORAL, EN EL QUE SE COMPRIME UNA COMPOSICION QUE CONTIENE CANTIDADES EFICACES DE AXETIL-CEFUROXIMO Y UN AGENTE DE DESINTEGRACION, FORMANDO UN NUCLEO DE TABLETA QUE SE DESINTEGRA INMEDIATAMENTE DESPUES DE LA ROTURA DE SU RECUBRIMIENTO PELICULAR AL SOMETER LA TABLETA A UN ENSAYO DE ROTURA, Y SE REVISTE EL NUCLEO DE LA TABLETA CON UNA COMPOSICION FORMADORA DE PELICULA EN UNA SOLUCION ACUOSA O NO ACUOSA, PROPORCIONANDO UN RECUBRIMIENTO PELICULAR QUE SIRVE PARA ENMASCARAR EL SABOR AMARGO DEL AXETIL-CEFUROXIMO Y QUE TIENE UN TIEMPO DE ROTURA DE MENOS DE 40 SEGUNDOS. EXISTEN VIAS ALTERNATIVAS PARA PREPARAR ESTA TABLETA QUE SE DESCRIBEN EN LA MEMORIA. LAS TABLETAS OBTENIDAS SON ESPECIALMENTE UTILES COMO ANTIBIOTICOS POR SU GRAN ACTIVIDAD CONTRA UNA AMPLIA GAMA DE MICROORGANISMOS GRAM-POSITIVOS Y GRAM-NEGATIVOS.
ES8602263A 1985-09-30 1986-09-29 Un procedimiento para la preparacion de una tableta farmaceutica para administracion oral Expired ES2002382A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858524001A GB8524001D0 (en) 1985-09-30 1985-09-30 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
ES2002382A6 true ES2002382A6 (es) 1988-08-01

Family

ID=10585921

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8602263A Expired ES2002382A6 (es) 1985-09-30 1986-09-29 Un procedimiento para la preparacion de una tableta farmaceutica para administracion oral

Country Status (29)

Country Link
US (1) US4897270A (es)
EP (1) EP0223365B1 (es)
JP (1) JP2661662B2 (es)
KR (1) KR940000233B1 (es)
AT (1) AT393081B (es)
AU (1) AU594082B2 (es)
BE (1) BE905518A (es)
CA (1) CA1282331C (es)
CH (1) CH672736A5 (es)
CY (1) CY1563A (es)
DE (2) DE3677710D1 (es)
DK (1) DK175349B1 (es)
ES (1) ES2002382A6 (es)
FR (1) FR2591597B1 (es)
GB (2) GB8524001D0 (es)
GR (1) GR862464B (es)
HK (1) HK84990A (es)
IE (1) IE59089B1 (es)
IL (1) IL80165A (es)
IT (1) IT1196644B (es)
LU (1) LU86613A1 (es)
NL (1) NL8602466A (es)
NO (1) NO173636C (es)
NZ (1) NZ217720A (es)
PH (1) PH25702A (es)
PT (1) PT83459B (es)
SA (1) SA91120189B1 (es)
SE (1) SE8604114L (es)
ZA (1) ZA867318B (es)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
NL193682C (nl) * 1987-05-14 2000-07-04 Glaxo Group Ltd Beklede cefuroximaxetilsamenstelling.
US4880636A (en) * 1988-05-13 1989-11-14 Franz Robert M Film coated tablet of ranitidine HCl
AT393955B (de) * 1990-03-30 1992-01-10 Martin Dr Leixnering Einrichtung zur nachbehandlung frischer beugesehnenverletzungen
FR2666506A1 (fr) * 1990-09-07 1992-03-13 Pf Medicament Comprime a liberation prolongee a base de 5-mononitrate d'isosorbide et son procede de preparation.
GB2256587A (en) * 1991-06-11 1992-12-16 American Cyanamid Co Acetazolamide in sustained release form
US5234696A (en) * 1991-12-27 1993-08-10 Abbott Laboratories Method of producing tablets, tablets produced thereby, and method of treatment using same
HRP970493A2 (en) * 1996-09-23 1998-08-31 Wienman E. Phlips Oral delayed immediate release medical formulation and method for preparing the same
CO4920215A1 (es) * 1997-02-14 2000-05-29 Novartis Ag Tabletas de oxacarbazepina recubiertas de una pelicula y metodo para la produccion de estas formulaciones
US20020022056A1 (en) 1997-02-14 2002-02-21 Burkhard Schlutermann Oxacarbazepine film-coated tablets
CA2209868C (en) * 1997-08-15 2001-08-14 Bernard Charles Sherman Pharmaceutical compositions comprising cefuroxime axetil
IN186539B (es) * 1997-09-29 2001-09-29 Ranbaxy Lab Ltd
EP1066040B1 (en) * 1998-03-03 2003-02-19 Daewoong Pharmaceutical Co., Ltd. Pharmaceutical composition containing cefuroxime axetil stable for moisture absorption
CA2239331C (en) * 1998-05-29 1999-11-30 Bernard Charles Sherman Pharmaceutical tablets comprising cefuroxime axetil
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
AT413647B (de) * 1998-11-26 2006-04-15 Sandoz Ag Verwendung eines copolymerisats aus 1-vinyl-2-pyrrolidon und vinylacetat zur herstellung von cefuroximaxetil-hältigen tabletten
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
PT1194124E (pt) * 1999-06-11 2004-02-27 Ranbaxy Lab Ltd Composicoes de sabor mascarado
IN191239B (es) 1999-06-11 2003-10-11 Ranbaxy Lab Ltd
FR2795962B1 (fr) * 1999-07-08 2003-05-09 Prographarm Laboratoires Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif
CA2280925A1 (en) 1999-07-29 2001-01-29 Bernard Charles Sherman Stabilized cefuroxime axetil
KR100342943B1 (ko) * 1999-08-04 2002-07-02 민경윤 비결정질 세푸록심 악세틸 고형분산체, 이의 제조 방법 및 이를 포함하는 경구투여용 조성물
JP2001122791A (ja) * 1999-10-20 2001-05-08 Boehringer Ingelheim Internatl Gmbh 下肢の慢性静脈不全の軽減および予防のための赤色ブドウ樹葉の水性抽出物よりなる食事補強剤
AT500063A1 (de) * 1999-11-23 2005-10-15 Sandoz Ag Beschichtete tablettenkerne
EP1414417A1 (en) * 2000-12-01 2004-05-06 Abdul Rehman Wockhardt Research Centre Khan Pharmaceutical formulation
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
HRP20020924A2 (en) * 2001-11-23 2003-10-31 Glaxo Group Ltd Pharmaceutical composition
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
KR100523082B1 (ko) * 2002-09-11 2005-10-20 (주)다산메디켐 쓴 맛이 은폐된 세푸록심악세틸 제제의 제약조성물 및 그의 제조방법
AU2003298180B2 (en) * 2002-12-31 2010-01-21 Boehringer Ingelheim International Gmbh Film coated tablet comprising an extract of red vine leaves
US20040151769A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Film coated tablet containing an extract of red vine leaves
US20050079213A1 (en) * 2003-06-06 2005-04-14 Unilab Pharmatech Ltd Pharmaceutical compositions
KR100552567B1 (ko) * 2003-08-23 2006-02-15 한국유나이티드제약 주식회사 수분 흡수에 안정하고 빠르게 붕해되는 세푸록심 악세틸을포함하는 정제의 조성물 및 제조 방법
US20050084540A1 (en) * 2003-10-17 2005-04-21 Indranil Nandi Taste masking antibiotic composition
EP1550450A1 (en) * 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a blood circulating-improving agent for the treatment of chronic venous insufficiencies
CN1909889B (zh) * 2004-01-09 2010-06-02 韩美药品株式会社 头孢呋辛酯颗粒及其制备方法
GB0403628D0 (en) * 2004-02-18 2004-03-24 Arrow Group Ltd Compression-coated tablets and the manufacture thereof
CA2551787C (en) * 2004-02-19 2014-04-08 Boehringer Ingelheim International Gmbh Composition for the treatment of chronic venous insufficiencies comprising an extract of red vine leaves and an anti-inflammatory agent
US8236349B2 (en) * 2004-04-12 2012-08-07 Bend Research Inc. Taste-masked drugs in rupturing multiparticulates
US20060099253A1 (en) * 2004-10-20 2006-05-11 Wyeth Antibiotic product formulation
US20070009573A1 (en) * 2005-07-07 2007-01-11 L N K International Method of forming immediate release dosage form
EP2091519B1 (en) * 2006-11-30 2015-06-24 Bend Research, Inc Multiparticulates of spray-coated drug and polymer on a meltable core
US11116728B2 (en) 2006-11-30 2021-09-14 Bend Research, Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
US8529914B2 (en) * 2010-06-28 2013-09-10 Richard C. Fuisz Bioactive dose having containing a material for modulating pH of a bodily fluid to help or hinder absorption of a bioactive
CA2848798C (en) 2012-02-22 2014-12-23 Duchesnay Inc. Formulation of doxylamine and pyridoxine and/or metabolites or salts thereof
WO2013151516A1 (en) * 2012-04-04 2013-10-10 Mahmut Bilgic Film tablet formulations comprising cefuroxime axetil and clavulanic acid
CN105338982B (zh) 2013-04-25 2017-10-10 杏林制药株式会社 固体药用组合物
CA2910121A1 (en) 2013-04-25 2014-10-30 Kyorin Pharmaceutical Co., Ltd. A pharmaceutical composition comprising a 1,4-dihydroquinoline carboxylic acid a cellulosic excipient and a salting-out agent
JP6379194B2 (ja) 2013-07-22 2018-08-22 デュシネイ・インコーポレイテッド 悪心及び嘔吐の管理のための組成物
EP3210607A4 (en) 2014-10-23 2018-06-06 Kyorin Pharmaceutical Co., Ltd. Solid pharmaceutical composition
CN118234494A (zh) 2021-11-10 2024-06-21 第一三共株式会社 具有优异溶出性质的药物组合物
DE202022100544U1 (de) 2022-01-31 2022-02-16 Ranjitsing Babasing Bayas Neue orale Streifen- oder Dünnfilmform von Diclofenac-Natrium

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3372015A (en) * 1963-11-15 1968-03-05 Pittsburgh Plate Glass Co Method of and apparatus for equalizing the cooling of a glass sheet supported on a bending mold
US3383236A (en) * 1964-04-17 1968-05-14 Merck & Co Inc Continuous pharmaceutical film coating process
FR1426194A (fr) * 1964-10-20 1966-01-28 Ile De France Nouvelle technique d'enrobage des comprimés
US3256111A (en) * 1964-12-04 1966-06-14 Abbott Lab Method for coating tablets
US3477864A (en) * 1965-05-07 1969-11-11 Sumitomo Chemical Co Process for coating pharmaceutical preparations with a hydroxy propyl methyl cellulose-sealing agent moisture-preventing film
US3539380A (en) * 1968-01-08 1970-11-10 Upjohn Co Methylcellulose and polyalkylene glycol coating of solid medicinal dosage forms
US3981984A (en) * 1968-04-01 1976-09-21 Colorcon Incorporated Color film coating of tablets and the like
DE2259646C2 (de) * 1972-12-06 1984-11-22 Hoechst Ag, 6230 Frankfurt Hochdosierte Tabletten von Cephalosporin-Derivaten sowie Verfahren zu ihrer Herstellung
US4140764A (en) * 1974-12-18 1979-02-20 Beecham Group Limited β-Lactamase inhibitors and process for their preparation
US4143129A (en) * 1975-10-11 1979-03-06 Lilly Industries Limited Cephalexin tablets
GB1571683A (en) * 1976-02-16 1980-07-16 Glaxo Operations Ltd Ester derivatives of cefuroxime
CA1093549A (en) * 1976-02-16 1981-01-13 Michael Gregson Cephalosporin antibiotics
CA1094545A (en) * 1976-02-16 1981-01-27 Michael Gregson Cephalosporin antibiotics
JPS52151717A (en) * 1976-06-09 1977-12-16 Shionogi & Co Ltd Sugar coating on solid preparations
JPS55129224A (en) * 1979-03-27 1980-10-06 Toyo Jozo Co Ltd Fine granules having improved taste
FI75578C (fi) * 1979-07-25 1988-07-11 Ciba Geigy Ag Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.
US4470980A (en) * 1980-03-07 1984-09-11 Interx Research Corp. Method of increasing oral absorption of β-lactam antibiotics
US4302440B1 (en) * 1980-07-31 1986-08-05 Easily-swallowed, powder-free and gastric-disintegrable aspirin tablet thinly-coated with hydroxypropyl methylcellulose and aqueous spray-coating preparation thereof
JPS5885813A (ja) * 1981-11-17 1983-05-23 Toyo Jozo Co Ltd 吸収性良好な製剤
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
DE3237575A1 (de) * 1982-10-09 1984-04-12 Dr. Karl Thomae Gmbh, 7950 Biberach Neue orale mopidamolformen
EP0114787B1 (de) * 1983-01-25 1991-09-25 Ciba-Geigy Ag Neue Peptidderivate
US4517179A (en) * 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
GB8320521D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
GB8320520D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
GB8324152D0 (en) * 1983-09-09 1983-10-12 Glaxo Group Ltd Chemical process
EP0147780A3 (en) * 1984-01-03 1987-03-11 Merck & Co. Inc. Drug delivery device
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
JPS60169416A (ja) * 1984-02-14 1985-09-02 Taisho Pharmaceut Co Ltd 素錠の表面処理方法
US4616008A (en) * 1984-05-02 1986-10-07 Takeda Chemical Industries, Ltd. Antibacterial solid composition for oral administration
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
NL193682C (nl) * 1987-05-14 2000-07-04 Glaxo Group Ltd Beklede cefuroximaxetilsamenstelling.

Also Published As

Publication number Publication date
EP0223365B1 (en) 1991-02-27
IL80165A0 (en) 1986-12-31
IT1196644B (it) 1988-11-16
NZ217720A (en) 1988-07-28
IE59089B1 (en) 1994-01-12
DE3633292A1 (de) 1987-04-09
CA1282331C (en) 1991-04-02
SE8604114L (sv) 1987-03-31
IL80165A (en) 1991-06-10
AU6323286A (en) 1987-04-02
KR940000233B1 (ko) 1994-01-12
GR862464B (en) 1987-02-02
DK462486A (da) 1987-03-31
GB2181052B (en) 1989-10-18
NO173636C (no) 1994-01-12
KR870002832A (ko) 1987-04-13
GB8524001D0 (en) 1985-11-06
ATA260986A (de) 1991-01-15
PT83459A (en) 1986-10-01
DK175349B1 (da) 2004-09-06
CY1563A (en) 1991-05-17
ZA867318B (en) 1987-05-27
EP0223365A3 (en) 1988-06-08
NO863863D0 (no) 1986-09-29
CH672736A5 (es) 1989-12-29
EP0223365A2 (en) 1987-05-27
FR2591597B1 (fr) 1989-06-02
JP2661662B2 (ja) 1997-10-08
IE862564L (en) 1987-03-30
GB8623340D0 (en) 1986-11-05
NL8602466A (nl) 1987-04-16
FR2591597A1 (fr) 1987-06-19
AT393081B (de) 1991-08-12
PH25702A (en) 1991-09-18
NO863863L (no) 1987-03-31
BE905518A (fr) 1987-03-30
SA91120189B1 (ar) 2001-10-07
HK84990A (en) 1990-10-25
SE8604114D0 (sv) 1986-09-29
DK462486D0 (da) 1986-09-29
LU86613A1 (fr) 1988-04-05
AU594082B2 (en) 1990-03-01
US4897270A (en) 1990-01-30
GB2181052A (en) 1987-04-15
IT8648492A0 (it) 1986-09-29
DE3677710D1 (de) 1991-04-04
NO173636B (no) 1993-10-04
JPS62123118A (ja) 1987-06-04
PT83459B (pt) 1989-05-12

Similar Documents

Publication Publication Date Title
ES2002382A6 (es) Un procedimiento para la preparacion de una tableta farmaceutica para administracion oral
CA2061520A1 (en) Delivery system for enhanced onset and increased potency
CA2112679A1 (en) Dosage form for delivering drug in short-time period
ES8304143A1 (es) "procedimiento para la preparacion de derivados de cefem".
UA29450C2 (uk) Похідні гідроксамової кислоти, спосіб їх одержання, спосіб впливу на хвороби та фармацевтична або ветеринарна композиція, що їх містить
ZA795530B (en) Pharmaceutical tablet for oral administration and process for its manufacture
HU900394D0 (en) Process for producing a new compound of medical effect and pharmaceutical preparatives containing it
NZ229891A (en) Pharmaceutical composition for the prevention of sexually transmitted diseases
ITBO920295A1 (it) Metodo e dispositivo per il dosaggio di un prodotto farmaceutico all'interno di capsule
AU552547B2 (en) Nonapeptide for treatment of drug withdrawal symptoms
AU8336982A (en) Nasal administration of b-blockers and dosage forms therefor
IE860785L (en) Composition for delivery of orally administered drugs
ES2010466A6 (es) Formas de administracion solidas, de rapida desintegracion.
ES2001094A6 (es) Un procedimiento para la preparacion de un derivado de guanina
EP0285550A3 (en) A percutaneous-administration-type pharmaceutical preparation of nitroglycerin
AU1304976A (en) Pharmaceutical dosage forms
EP0282156A3 (en) Prevention of contact allergy by coadministration of a corticosteroid with a sensitizing drug
JPS57114508A (en) Pharmaceutical medicine for use of choline- action suppressive drug
AU683229B2 (en) Tilidin dihydrogen orthophosphate, method of preparing it and pharmaceutical preparations containing it
MY106776A (en) Solid dosage forms of almokalant and processes for manufacture thereof.
GB1292496A (en) Dosage units of contraceptive preparations for human use
ZW20982A1 (en) Aminooxazolyl compounds processes for their manufacture pharmaceutical preparations containing these compounds and the use of the latter
GB950162A (en) Medicines for the treatment of hepatic disorders
JPS5215813A (en) Preparation of stable medicine including homopyrimidazole derivative for aural administration
JO1718B1 (en) Solid dosage form of Muclant drug and its manufacturing processes

Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-09-29

GD1A Contractual licences

Effective date: 20040913

FD1A Patent lapsed

Effective date: 20060930