ES2002382A6 - Un procedimiento para la preparacion de una tableta farmaceutica para administracion oral - Google Patents

Un procedimiento para la preparacion de una tableta farmaceutica para administracion oral

Info

Publication number
ES2002382A6
ES2002382A6 ES8602263A ES8602263A ES2002382A6 ES 2002382 A6 ES2002382 A6 ES 2002382A6 ES 8602263 A ES8602263 A ES 8602263A ES 8602263 A ES8602263 A ES 8602263A ES 2002382 A6 ES2002382 A6 ES 2002382A6
Authority
ES
Spain
Prior art keywords
cefuroxime axetil
dragee
film coat
film
tablet core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8602263A
Other languages
English (en)
Inventor
David Deutsch
Jamshed Anwar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10585921&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2002382(A6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES2002382A6 publication Critical patent/ES2002382A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UNA TABLETA FARMACEUTICA PARA ADMINISTRACION ORAL, EN EL QUE SE COMPRIME UNA COMPOSICION QUE CONTIENE CANTIDADES EFICACES DE AXETIL-CEFUROXIMO Y UN AGENTE DE DESINTEGRACION, FORMANDO UN NUCLEO DE TABLETA QUE SE DESINTEGRA INMEDIATAMENTE DESPUES DE LA ROTURA DE SU RECUBRIMIENTO PELICULAR AL SOMETER LA TABLETA A UN ENSAYO DE ROTURA, Y SE REVISTE EL NUCLEO DE LA TABLETA CON UNA COMPOSICION FORMADORA DE PELICULA EN UNA SOLUCION ACUOSA O NO ACUOSA, PROPORCIONANDO UN RECUBRIMIENTO PELICULAR QUE SIRVE PARA ENMASCARAR EL SABOR AMARGO DEL AXETIL-CEFUROXIMO Y QUE TIENE UN TIEMPO DE ROTURA DE MENOS DE 40 SEGUNDOS. EXISTEN VIAS ALTERNATIVAS PARA PREPARAR ESTA TABLETA QUE SE DESCRIBEN EN LA MEMORIA. LAS TABLETAS OBTENIDAS SON ESPECIALMENTE UTILES COMO ANTIBIOTICOS POR SU GRAN ACTIVIDAD CONTRA UNA AMPLIA GAMA DE MICROORGANISMOS GRAM-POSITIVOS Y GRAM-NEGATIVOS.
ES8602263A 1985-09-30 1986-09-29 Un procedimiento para la preparacion de una tableta farmaceutica para administracion oral Expired ES2002382A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858524001A GB8524001D0 (en) 1985-09-30 1985-09-30 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
ES2002382A6 true ES2002382A6 (es) 1988-08-01

Family

ID=10585921

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8602263A Expired ES2002382A6 (es) 1985-09-30 1986-09-29 Un procedimiento para la preparacion de una tableta farmaceutica para administracion oral

Country Status (29)

Country Link
US (1) US4897270A (es)
EP (1) EP0223365B1 (es)
JP (1) JP2661662B2 (es)
KR (1) KR940000233B1 (es)
AT (1) AT393081B (es)
AU (1) AU594082B2 (es)
BE (1) BE905518A (es)
CA (1) CA1282331C (es)
CH (1) CH672736A5 (es)
CY (1) CY1563A (es)
DE (2) DE3677710D1 (es)
DK (1) DK175349B1 (es)
ES (1) ES2002382A6 (es)
FR (1) FR2591597B1 (es)
GB (2) GB8524001D0 (es)
GR (1) GR862464B (es)
HK (1) HK84990A (es)
IE (1) IE59089B1 (es)
IL (1) IL80165A (es)
IT (1) IT1196644B (es)
LU (1) LU86613A1 (es)
NL (1) NL8602466A (es)
NO (1) NO173636C (es)
NZ (1) NZ217720A (es)
PH (1) PH25702A (es)
PT (1) PT83459B (es)
SA (1) SA91120189B1 (es)
SE (1) SE8604114L (es)
ZA (1) ZA867318B (es)

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Also Published As

Publication number Publication date
EP0223365B1 (en) 1991-02-27
IL80165A0 (en) 1986-12-31
IT1196644B (it) 1988-11-16
NZ217720A (en) 1988-07-28
IE59089B1 (en) 1994-01-12
DE3633292A1 (de) 1987-04-09
CA1282331C (en) 1991-04-02
SE8604114L (sv) 1987-03-31
IL80165A (en) 1991-06-10
AU6323286A (en) 1987-04-02
KR940000233B1 (ko) 1994-01-12
GR862464B (en) 1987-02-02
DK462486A (da) 1987-03-31
GB2181052B (en) 1989-10-18
NO173636C (no) 1994-01-12
KR870002832A (ko) 1987-04-13
GB8524001D0 (en) 1985-11-06
ATA260986A (de) 1991-01-15
PT83459A (en) 1986-10-01
DK175349B1 (da) 2004-09-06
CY1563A (en) 1991-05-17
ZA867318B (en) 1987-05-27
EP0223365A3 (en) 1988-06-08
NO863863D0 (no) 1986-09-29
CH672736A5 (es) 1989-12-29
EP0223365A2 (en) 1987-05-27
FR2591597B1 (fr) 1989-06-02
JP2661662B2 (ja) 1997-10-08
IE862564L (en) 1987-03-30
GB8623340D0 (en) 1986-11-05
NL8602466A (nl) 1987-04-16
FR2591597A1 (fr) 1987-06-19
AT393081B (de) 1991-08-12
PH25702A (en) 1991-09-18
NO863863L (no) 1987-03-31
BE905518A (fr) 1987-03-30
SA91120189B1 (ar) 2001-10-07
HK84990A (en) 1990-10-25
SE8604114D0 (sv) 1986-09-29
DK462486D0 (da) 1986-09-29
LU86613A1 (fr) 1988-04-05
AU594082B2 (en) 1990-03-01
US4897270A (en) 1990-01-30
GB2181052A (en) 1987-04-15
IT8648492A0 (it) 1986-09-29
DE3677710D1 (de) 1991-04-04
NO173636B (no) 1993-10-04
JPS62123118A (ja) 1987-06-04
PT83459B (pt) 1989-05-12

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-09-29

GD1A Contractual licences

Effective date: 20040913

FD1A Patent lapsed

Effective date: 20060930