HU900394D0 - Process for producing a new compound of medical effect and pharmaceutical preparatives containing it - Google Patents
Process for producing a new compound of medical effect and pharmaceutical preparatives containing itInfo
- Publication number
- HU900394D0 HU900394D0 HU90394A HU39489A HU900394D0 HU 900394 D0 HU900394 D0 HU 900394D0 HU 90394 A HU90394 A HU 90394A HU 39489 A HU39489 A HU 39489A HU 900394 D0 HU900394 D0 HU 900394D0
- Authority
- HU
- Hungary
- Prior art keywords
- producing
- new compound
- medical effect
- preparatives containing
- pharmaceutical preparatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
- C07D265/22—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28779688A | 1988-12-21 | 1988-12-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
HU900394D0 true HU900394D0 (en) | 1991-09-30 |
HUT58310A HUT58310A (en) | 1992-02-28 |
Family
ID=23104392
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU90394A HUT58310A (en) | 1988-12-21 | 1989-12-15 | Anti-atherosclerotic and anti-thrombotic 1-benzopyran-4-one- and 2-amino-1,3-benzoxazin-4-one derivatives, process for producing them and pharmaceutical compositions containing them |
HU95P/P00411P HU211339A9 (en) | 1988-12-21 | 1995-06-23 | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU95P/P00411P HU211339A9 (en) | 1988-12-21 | 1995-06-23 | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0459983A1 (en) |
JP (1) | JPH04502322A (en) |
AU (1) | AU634994B2 (en) |
DK (1) | DK118791D0 (en) |
FI (1) | FI912995A0 (en) |
HU (2) | HUT58310A (en) |
RU (1) | RU2118321C1 (en) |
WO (1) | WO1990006921A1 (en) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991019707A2 (en) * | 1990-06-20 | 1991-12-26 | The Upjohn Company | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
KR920702353A (en) * | 1990-06-29 | 1992-09-03 | 로버트 에이. 아미테이지 | 2-amino-6-phenyl-4H-pyran-4-one for the treatment of atherosclerosis and thrombosis |
US5302613A (en) * | 1990-06-29 | 1994-04-12 | The Upjohn Company | Antiatheroscleroic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones |
US5252735A (en) * | 1990-06-29 | 1993-10-12 | The Upjohn Company | Antiatherosclerotic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones |
IL112764A0 (en) * | 1994-03-18 | 1995-05-26 | Ferrer Int | New chromene derivatives |
CA2182932A1 (en) * | 1995-08-10 | 1997-02-11 | Koju Watanabe | Chromone derivative, process for preparing same and pharmaceutical composition |
DE19850131A1 (en) * | 1998-10-30 | 2000-05-04 | Merck Patent Gmbh | Chromenon and chromanone derivatives |
AU3704400A (en) * | 1999-03-04 | 2000-09-21 | E.I. Du Pont De Nemours And Company | Fused bicyclic oxazinone and thiazinone fungicides |
DK1257537T3 (en) | 2000-01-24 | 2007-10-01 | Astrazeneca Ab | Therapeutic morpholino-substituted compounds |
GB0119865D0 (en) | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
GB0119863D0 (en) | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
US7049313B2 (en) | 2002-02-25 | 2006-05-23 | Kudos Pharmaceuticals Ltd. | ATM inhibitors |
JP4664597B2 (en) | 2002-04-17 | 2011-04-06 | サイトキネティクス・インコーポレーテッド | Compounds, compositions and methods |
AU2003252025A1 (en) | 2002-07-17 | 2004-02-02 | Cytokinetics, Inc. | Compounds, compositions, and methods |
JP4646626B2 (en) * | 2002-08-16 | 2011-03-09 | アストラゼネカ アクチボラグ | Inhibition of phosphoinositide 3-kinase β |
CN101260104A (en) * | 2002-08-16 | 2008-09-10 | 阿斯利康(瑞典)有限公司 | Inhibition of phosphoinositide 3-kinase beta |
CA2525383C (en) | 2003-06-06 | 2012-03-06 | Arexis Ab | Use of heterocyclic compounds as scce inhibitors |
CN100518740C (en) * | 2003-06-06 | 2009-07-29 | 阿里克斯股份公司 | Use of heterocyclic compounds as SCCE inhibitors |
US7429660B2 (en) | 2003-08-13 | 2008-09-30 | Kudos Pharmaceuticals Limited | ATM inhibitors |
TR200808208T1 (en) | 2003-12-09 | 2008-12-22 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Suppression of an immune response or treatment of a proliferative disease |
US20070238731A1 (en) | 2004-09-20 | 2007-10-11 | Kudos Pharmaceuticals Limited | Dna-Pk Inhibitors |
TW200638938A (en) | 2005-02-09 | 2006-11-16 | Kudos Pharm Ltd | ATM inhibitors |
AR053358A1 (en) | 2005-04-15 | 2007-05-02 | Cancer Rec Tech Ltd | DNA INHIBITORS - PK |
WO2009038064A1 (en) * | 2007-09-19 | 2009-03-26 | Institute Of Medicinal Molecular Design, Inc. | Heterocyclic derivative having inhibitory activity on type-i 11β-hydroxysteroid dehydrogenase |
AU2009295948B2 (en) * | 2008-09-29 | 2013-12-05 | GlaxoSmithKline, LLC | Quinazolinone, quinolone and related analogs as sirtuin modulators |
US8399460B2 (en) | 2009-10-27 | 2013-03-19 | Astrazeneca Ab | Chromenone derivatives |
US8530470B2 (en) | 2011-04-13 | 2013-09-10 | Astrazeneca Ab | Chromenone derivatives |
RU2468018C1 (en) * | 2011-10-06 | 2012-11-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский университет дружбы народов" (РУДН) | Method of producing 4-oxo-4h-chromene derivatives containing vinyl and enamine groups |
EP2808322B1 (en) * | 2012-01-26 | 2017-08-23 | Daiichi Sankyo Company, Limited | Chromone derivative having osteogenesis promoting effect |
TW201412727A (en) * | 2012-08-24 | 2014-04-01 | Daiichi Sankyo Co Ltd | Chromone derivative having linear side chain |
KR102222346B1 (en) | 2013-03-04 | 2021-03-02 | 아스트라제네카 아베 | Combination treatment |
CN108947952B (en) * | 2017-05-24 | 2021-09-21 | 中国医学科学院药物研究所 | 2-substituted amino-5-trifluoromethyl-8-nitrobenz (thio) pyran-4-ketone compound and preparation method and application thereof |
CN108929329B (en) * | 2017-05-24 | 2020-12-11 | 中国医学科学院药物研究所 | 2-azacyclo-5-trifluoromethyl-8-nitrobenz (thio) pyran-4-ones |
AR121719A1 (en) | 2020-04-03 | 2022-06-29 | Petra Pharma Corp | ALLESTERIC INHIBITORS OF CHROMENONE OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASES |
IL307950A (en) | 2021-05-03 | 2023-12-01 | Petra Pharma Corp | Allosteric chromenone inhibitors of phosphoinositide 3-kinase (pi3k) for the treatment of disease |
TWI829179B (en) | 2021-05-27 | 2024-01-11 | 美商佩特拉製藥公司 | Allosteric chromenone inhibitors of phosphoinositide 3-kinase (pi3k) for the treatment of disease |
TW202329930A (en) | 2021-09-30 | 2023-08-01 | 美商佩特拉製藥公司 | Allosteric chromenone inhibitors of phosphoinositide 3-kinase (pi3k) for the treatment of disease |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2205913A1 (en) * | 1972-02-08 | 1973-08-16 | Thiemann Chem Pharm Fab | 2-AMINO-3-HYDROXY-CHROMONE DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
DE2555290A1 (en) * | 1975-12-09 | 1977-06-16 | Boehringer Mannheim Gmbh | NEW BENZOPYRONE DERIVATIVES AND METHOD FOR THEIR PRODUCTION |
US4412071A (en) * | 1982-05-17 | 1983-10-25 | The Upjohn Company | Antiatherosclerotic compositions |
ZA873745B (en) * | 1986-06-04 | 1988-10-26 | Daiichi Seiyaku Co | Benzopyran derivatives |
IL89840A (en) * | 1988-04-06 | 1996-10-31 | Lipha | Substituted flavonoid compounds and salts thereof their preparation and pharmaceutical composition containing them |
-
1989
- 1989-12-15 EP EP90900649A patent/EP0459983A1/en not_active Ceased
- 1989-12-15 JP JP2501394A patent/JPH04502322A/en active Pending
- 1989-12-15 AU AU48071/90A patent/AU634994B2/en not_active Ceased
- 1989-12-15 WO PCT/US1989/005526 patent/WO1990006921A1/en not_active Application Discontinuation
- 1989-12-15 HU HU90394A patent/HUT58310A/en unknown
- 1989-12-15 RU SU4895676A patent/RU2118321C1/en active
-
1991
- 1991-06-19 FI FI912995A patent/FI912995A0/en unknown
- 1991-06-19 DK DK911187A patent/DK118791D0/en not_active Application Discontinuation
-
1995
- 1995-06-23 HU HU95P/P00411P patent/HU211339A9/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU4807190A (en) | 1990-07-10 |
AU634994B2 (en) | 1993-03-11 |
FI912995A0 (en) | 1991-06-19 |
JPH04502322A (en) | 1992-04-23 |
RU2118321C1 (en) | 1998-08-27 |
DK118791A (en) | 1991-06-19 |
EP0459983A1 (en) | 1991-12-11 |
WO1990006921A1 (en) | 1990-06-28 |
DK118791D0 (en) | 1991-06-19 |
HUT58310A (en) | 1992-02-28 |
HU211339A9 (en) | 1995-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
DFD9 | Temporary prot. cancelled due to non-payment of fee |