EP4096637A1 - Protection anti-allergène contre les urushiols - Google Patents

Protection anti-allergène contre les urushiols

Info

Publication number
EP4096637A1
EP4096637A1 EP21703608.6A EP21703608A EP4096637A1 EP 4096637 A1 EP4096637 A1 EP 4096637A1 EP 21703608 A EP21703608 A EP 21703608A EP 4096637 A1 EP4096637 A1 EP 4096637A1
Authority
EP
European Patent Office
Prior art keywords
peptides
skin
amino acids
allergens
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21703608.6A
Other languages
German (de)
English (en)
Inventor
Yvonne WÖHRMANN
Jörn Hendrik Reuter
Wilfried Siefken
Judith SEIDEL
Anna RINAS
Marlis RIEDEL
Tanja BUSSMANN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf AG
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Publication of EP4096637A1 publication Critical patent/EP4096637A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers

Definitions

  • the skin forms a barrier that protects the human organism from liquid or solid foreign substances. Nevertheless, foreign substances and thus potential allergens can penetrate. This can trigger an immune response, causing the affected skin area to become inflamed.
  • the immune system made up of antibodies, white blood cells, mast cells, complement proteins, and other substances, defends the body against foreign substances (also called antigens).
  • the immune system of susceptible people can react excessively when they come into contact with certain substances (allergens) in the environment or in food or medication that are harmless to most people. The result is an allergic reaction. Some people are allergic to only one substance. Others are allergic to many substances. Around a quarter of all citizens of Germany suffer from allergies.
  • the first three allergy types are mediated via the body fluids and the antibodies contained therein, including factors (humoral), while the fourth allergy type is cell-mediated (via T cells).
  • mixed images also occur.
  • Type I The allergy of the immediate type
  • Simple aqueous or lipid-containing formulations through to complex preparation forms are possible depending on the area of application.
  • the preparations according to the invention advantageously comprise one or more film formers.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Des substances allergisantes, des allergènes tels que les urushiols, sont interceptées par des peptides se composant de 2-10 acides aminés, au moins un acide aminé présentant une ou plusieurs chaînes latérales réactives. Cette action barrière des peptides, notamment dans des préparations pour application topique, conduit à une forme thérapeutique anti-allergie d'un nouveau type.
EP21703608.6A 2020-01-29 2021-01-26 Protection anti-allergène contre les urushiols Pending EP4096637A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102020201019.6A DE102020201019A1 (de) 2020-01-29 2020-01-29 Allergenschutz für die Haut
PCT/EP2021/051719 WO2021151872A1 (fr) 2020-01-29 2021-01-26 Protection anti-allergène contre les urushiols

Publications (1)

Publication Number Publication Date
EP4096637A1 true EP4096637A1 (fr) 2022-12-07

Family

ID=74347076

Family Applications (3)

Application Number Title Priority Date Filing Date
EP21703382.8A Pending EP4096636A1 (fr) 2020-01-29 2021-01-26 Préparation à application topique comprenant des peptides pour protéger la peau contre les allergènes
EP21703610.2A Pending EP4096638A1 (fr) 2020-01-29 2021-01-26 Protection de la peau contre les allergènes
EP21703608.6A Pending EP4096637A1 (fr) 2020-01-29 2021-01-26 Protection anti-allergène contre les urushiols

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP21703382.8A Pending EP4096636A1 (fr) 2020-01-29 2021-01-26 Préparation à application topique comprenant des peptides pour protéger la peau contre les allergènes
EP21703610.2A Pending EP4096638A1 (fr) 2020-01-29 2021-01-26 Protection de la peau contre les allergènes

Country Status (4)

Country Link
US (3) US20230103675A1 (fr)
EP (3) EP4096636A1 (fr)
DE (1) DE102020201019A1 (fr)
WO (3) WO2021151877A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240226046A1 (en) * 2023-01-11 2024-07-11 Douglas J. Tataryn Composition containing lysine for the treatment of poison ivy, composition containing lysine for the prevention of poison ivy, processes, and method of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030043A1 (fr) * 1995-03-24 1996-10-03 Ophidian Pharmaceuticals Traitement contre escherichia coli producteur de verotoxines
US7498310B1 (en) 1998-08-13 2009-03-03 Beiersdorf Ag Cosmetic or dermatological preparations comprising oligopeptides for lightening the skin of age marks and/or for preventing tanning of the skin, in particular tanning of the skin caused by UV radiation
IL172896A0 (en) * 2005-12-29 2006-06-11 Yeda Res & Dev Cxcr4 inhibition
FR2975904B1 (fr) 2011-06-01 2013-08-23 Sederma Sa Nouvelle utilisation topique, cosmetique ou dermopharmaceutique, d'un melange comprenant un tripeptide du type ghk et un tetrapeptide du type gqpr
US20120321603A1 (en) * 2011-06-16 2012-12-20 Nayan Patel Composition and method for stabilization and delivery of therapeutic molecules
US20180296491A1 (en) * 2015-04-27 2018-10-18 University Of Rochester Nanoparticle therapeutics for treating skin inflammatory disorders
SG11202004391QA (en) * 2017-11-15 2020-06-29 Nat Univ Singapore Derivatives of ppd useful for coloring hair and skin

Also Published As

Publication number Publication date
WO2021151872A1 (fr) 2021-08-05
WO2021151879A1 (fr) 2021-08-05
WO2021151877A1 (fr) 2021-08-05
US20230181674A1 (en) 2023-06-15
EP4096636A1 (fr) 2022-12-07
US20230109157A1 (en) 2023-04-06
DE102020201019A1 (de) 2021-07-29
US20230103675A1 (en) 2023-04-06
EP4096638A1 (fr) 2022-12-07

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Owner name: BEIERSDORF AG