EP3066510A1 - Digitalmikroskop mit schwenkstativ, verfahren zur kalibrierung und verfahren zur automatischen fokus- und bildmittennachführung für ein solches digitalmikroskop - Google Patents
Digitalmikroskop mit schwenkstativ, verfahren zur kalibrierung und verfahren zur automatischen fokus- und bildmittennachführung für ein solches digitalmikroskopInfo
- Publication number
- EP3066510A1 EP3066510A1 EP14790577.2A EP14790577A EP3066510A1 EP 3066510 A1 EP3066510 A1 EP 3066510A1 EP 14790577 A EP14790577 A EP 14790577A EP 3066510 A1 EP3066510 A1 EP 3066510A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- swivel
- angle
- axis
- digital microscope
- pivot
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 238000000034 method Methods 0.000 title claims abstract description 49
- 230000001419 dependent effect Effects 0.000 claims abstract description 4
- 230000003287 optical effect Effects 0.000 claims description 27
- 238000004091 panning Methods 0.000 claims description 3
- 238000012545 processing Methods 0.000 claims description 2
- 238000006073 displacement reaction Methods 0.000 claims 3
- 239000013598 vector Substances 0.000 description 26
- 230000008569 process Effects 0.000 description 19
- 239000000203 mixture Substances 0.000 description 18
- 238000012937 correction Methods 0.000 description 17
- 230000006870 function Effects 0.000 description 9
- 230000008901 benefit Effects 0.000 description 5
- 230000008859 change Effects 0.000 description 4
- 238000003384 imaging method Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000013459 approach Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 230000001133 acceleration Effects 0.000 description 1
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Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/241—Devices for focusing
- G02B21/245—Devices for focusing using auxiliary sources, detectors
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16M—FRAMES, CASINGS OR BEDS OF ENGINES, MACHINES OR APPARATUS, NOT SPECIFIC TO ENGINES, MACHINES OR APPARATUS PROVIDED FOR ELSEWHERE; STANDS; SUPPORTS
- F16M11/00—Stands or trestles as supports for apparatus or articles placed thereon ; Stands for scientific apparatus such as gravitational force meters
- F16M11/02—Heads
- F16M11/04—Means for attachment of apparatus; Means allowing adjustment of the apparatus relatively to the stand
- F16M11/043—Allowing translations
- F16M11/046—Allowing translations adapted to upward-downward translation movement
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16M—FRAMES, CASINGS OR BEDS OF ENGINES, MACHINES OR APPARATUS, NOT SPECIFIC TO ENGINES, MACHINES OR APPARATUS PROVIDED FOR ELSEWHERE; STANDS; SUPPORTS
- F16M11/00—Stands or trestles as supports for apparatus or articles placed thereon ; Stands for scientific apparatus such as gravitational force meters
- F16M11/02—Heads
- F16M11/18—Heads with mechanism for moving the apparatus relatively to the stand
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16M—FRAMES, CASINGS OR BEDS OF ENGINES, MACHINES OR APPARATUS, NOT SPECIFIC TO ENGINES, MACHINES OR APPARATUS PROVIDED FOR ELSEWHERE; STANDS; SUPPORTS
- F16M11/00—Stands or trestles as supports for apparatus or articles placed thereon ; Stands for scientific apparatus such as gravitational force meters
- F16M11/20—Undercarriages with or without wheels
- F16M11/2007—Undercarriages with or without wheels comprising means allowing pivoting adjustment
- F16M11/2021—Undercarriages with or without wheels comprising means allowing pivoting adjustment around a horizontal axis
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/0012—Surgical microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/241—Devices for focusing
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/26—Stages; Adjusting means therefor
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/365—Control or image processing arrangements for digital or video microscopes
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16M—FRAMES, CASINGS OR BEDS OF ENGINES, MACHINES OR APPARATUS, NOT SPECIFIC TO ENGINES, MACHINES OR APPARATUS PROVIDED FOR ELSEWHERE; STANDS; SUPPORTS
- F16M2200/00—Details of stands or supports
- F16M2200/02—Locking means
- F16M2200/021—Locking means for rotational movement
Definitions
- DIGITAL MICROSCOPE WITH SWIVEL STATE, METHOD OF CALIBRATION, AND METHOD FOR AUTOMATIC FOCUS AND PICTURE IMPLEMENTATION FOR SUCH A DIGITAL MICROSCOPE
- the invention relates to a digital microscope having the features of the preamble of claim 1, a method for
- DE 42 13 312 AI shows a surgical microscope in which the focusing speed is set in dependence on the magnification set to allow a focus, tilt or tilt adjustment.
- the zoom motor setting serves as a control signal for the focus, the X or Y setting.
- DE 697 16 018 T2 and US 5,825,536 disclose control devices for surgical microscopes with multipart articulated arms. Motors are driven to drive the plurality of sub-arms to execute predetermined ones
- an operating force is determined in the direction of several axes, to control the arms and joints so that the operation is supported.
- An angle sensor is used to determine the current angle of each joint to calculate the position and motion profile of the microscope.
- US 2005/0117207 A1 shows a surgical microscope with a multi-part articulated arm and a controller that the
- JP-2001059599-A2 and JP-2010102344-A2 a Schwenkarmstativ for digital microscopes is described, which includes a pivotable about a horizontal axis of rotation pivot arm.
- the swivel arm contains an upper focusing unit, which can be moved roughly along the height of a pillar for pre-adjustment and clamped by a handwheel.
- the above information refers to the vertical adjustment of the swivel arm, d. H. at around the
- JP 2013-072996 describes a microscope system with which it is possible to correct a misplacement and focus shift of an observation point.
- a memory unit status information about states are stored in which the focus adjustment with the axis of rotation of the
- the calibration is elaborate because, due to manufacturing tolerances, wheelbases and axis positions may vary depending on the device.
- the object of the invention is a digital microscope with a swivel stand and a method for its
- the digital microscope is to be calibrated in such a way that it is also suitable for the inexperienced
- the object is achieved by a digital microscope having the features of claim 1, by a method having the features of claim 7 and by a method having the features of claim 10.
- the digital microscope initially comprises, in a known manner, an optical unit which has at least one objective and one
- Image processing unit includes. A longitudinal axis of the
- Lens forms an optical axis (Z-axis).
- a pivoting stand has a pivotable about a pivot axis (Y-axis) pivoting arm on which a support for receiving the optical unit is preferably motorized
- An object table is preferably motorized in at least two axes which are preferably perpendicular to one another
- Swivel axis (Y-axis) is aligned.
- Object table and swivel stand are preferably arranged on a base.
- the digital microscope also has a control unit for controlling the optical unit, the swivel stand and the stage.
- the pivoting stand comprises an angle sensor for determining a current pivoting angle of the pivoting arm. Using the determined pivoting angle is in the Control unit possibly a focus tracking and a
- a method according to the invention for calibrating a digital microscope having a swivel stand comprises the steps
- Swing arm (07) vertical axes (X, Y);
- Image center tracking when operating the swivel arm is used.
- This calibration procedure is preferably ex works
- object coordinates are called
- Relative coordinates are displayed which do not change during automatic focus and image center tracking.
- the position of the pivot axis relative to the observed object detail is assumed to be unknown.
- the height of the object that can be used for swiveling can be increased compared with the prior art.
- the swivel stand is also more stable and cheaper to produce, as can be dispensed with additional adjustment points and / or tighter tolerance of all components relevant to the swivel function. Due to the substitution by the calibration method according to the invention, the user only needs to perform a likewise simplified set-up procedure. This allows the operation also for inexperienced with regard to adjustment processes users and shortens the time required to provide a deviation-minimized pivot function drastically.
- the object plane or the focused object detail does not have to lie in the height of the actually effective rotation axis.
- the method is not restricted to object heights which may not be greater than the usable guide path of the lower Z guide below the actually effective axis of rotation. This can possibly even one of the two Z-guides incl. Save control, provided that the traversing ranges of the X-axis and the remaining Z-axis are dimensioned sufficiently large.
- inventive methods achieve cost savings and simplification of the operation with faster available results a significant optimization of the orientation of the product to the target audience.
- the angle sensor is by means of two inertial sensors
- the angle value of the inertial sensor of the moving part is to be set to the angle value of the inertial sensor of the stand within the framework of a one-time calibration, so that a differential angle of 0 ° for the detent position
- Tripod with acceptable residual error can be used.
- the angle sensor can of course be designed in other ways, for example, optoelectronic, magnetic and electrically operating angle encoders are suitable.
- the carrier and the stage are motorized movable.
- Deviations due to the then missing motorization can not be done automatically, but is done by the user on the basis of the then displayed as a target X and Z coordinates.
- an object height can also be read directly.
- the object plane is preferably positioned above the upper Z-guide in the height or Z-position of the actually effective rotation axis, the coordinate display for the upper Z-guide indicating the value NULL. Then the object height can be read directly via the coordinate display for the lower Z guide, which can be communicated to the user by a comment correspondingly displayed with the coordinates.
- Object height for the pivoting movement can be increased according to the invention, so that a pivoting movement is also supported for object heights that are greater than the guide path of the lower Z-guide.
- the object detail is preferably executed as a cross.
- the legs of the cross in the X direction are preferably sufficiently long for all practically occurring deviations.
- Fig. 1 a front view of an inventive
- FIG. 2 a side view of the one shown in FIG.
- FIG. 3 is a front view of that shown in FIG.
- Fig. 4 a vectorial representation of the geometric
- Digital microscope with a tilted swivel arm unc corrected focus a front view of the digital microscope shown in Figure 1 with a tilted swivel arm, corrected focus and corrected image center.
- Fig. 9 the digital microscope with an extended usable
- Fig. 10 the digital microscope with an extended usable
- FIG. 12 shows steps of a customer-side method for using the swivel function
- Fig. 13 Steps of a customer-side setting of the
- FIG. 14 Steps of an automatic correction process in a Schwenkarmbetuschist.
- Figures 1 to 3 show a digital microscope with a swivel stand in different views and with different inclined settings of a swivel tripod.
- FIG. 1 contains a representation of the front view of the digital microscope as seen by the user
- FIG. 2 shows a side view from the left to the swivel stand Ol.
- a spatial coordinate system is introduced, which, viewed from the representation plane of FIG. 1, comprises a positive X-axis pointing to the right, a Y-axis pointing positively into the image plane, and a Z-axis facing upwards.
- the pivoting stand Ol comprises a stand base 02, on which a bearing block 03 is mounted, in which a bearing for a pivotable about a pivot axis 04 joint part 06 is integrated with a fixed thereto pivot arm 07.
- a bearing for a pivotable about a pivot axis 04 joint part 06 is integrated with a fixed thereto pivot arm 07.
- a carrier 09 which accommodates an optical unit 11, can be adjusted in the Z position relative to a reference position Z Ro .
- Reference position Z Ro of the (motorized) upper Z-guide 08 is indicated relative to the pivot axis 04 and is formed by the defined position approach via a suitable
- This sensor device during the initialization process of the (motorized) upper Z-guide 08.
- This sensor device is formed for example by a co-moving in the Z-movement switching flag and a fixedly mounted
- Fork coupler (a light barrier), which stops the Z movement during the initialization process, as soon as the
- Switching state of the fork coupler changes by the switching flag moved into the fork coupler.
- FIGS. 1 and 2 by way of example, a first Z position Z 0 i of the carrier 09 relative to the reference position Z Ro for the parts movable via the (motorized) upper Z-guide 08 is shown, wherein the carrier 09 accommodates the optical unit 11, which includes a zoom system, an integrated illumination and camera (not shown), as well as a lens 12.
- the optical unit 11 which includes a zoom system, an integrated illumination and camera (not shown), as well as a lens 12.
- the first Z position Z 0 i is characterized in that an object detail 13, which is located on an upper side of an object 14, in the vertical position of the swivel arm 07 is imaged sharply on an image sensor, not shown, wherein the Z coordinates of the object detail 13 and the
- Swivel axis 04 are not identical.
- a preferably motorized lower Z-guide 16 is mounted, wherein the motorized lower Z-guide 16 could also be mounted alternatively on the bearing block 03.
- the Rear side of the swivel stand Ol is preferably covered by a cover 17.
- (Motorized) lower Z-guide 16 is a preferably motorized object table 18 is arranged, which includes a table top 19, in which an incident light insert plate 20, whose surface 21 serves as object support, is integrated.
- About the (motorized) stage 18 can be an X position of the object detail 13 relative to a reference position X R and the Y position of the object detail 13 relative to a
- Reference position Y R vary.
- Z Ru , X R and Y R the above comments on
- Object detail 13 of the placed on the surface 21 of the incident-light insert plate 20 object 14 should be located in the center of the image. Since the practically occurring here as well
- FIGS 1 and 2 show the pivoting stand 01 in
- Object 14 is located in an object plane of the imaging system, wherein the upper side also contains the object detail 13 and a compensation length a L describes the distance of an end face 22 of the objective 12 relative to the object plane in the focused state.
- the object 14 has a height h up to the top side to be focussed or the object part 13.
- the Schwenkarmamba is blocked by a not shown here, arranged around the pivot axis 04, high torque magnetic brake.
- the blocking can be canceled for the duration of the key press of a button 23 according to Figure 1 on the release of the high torque magnetic brake.
- an ergonomically shaped portion 24 with a handle surface 25 at the upper end of the pivot arm 07 can thus be a swivel angle quickly and continuously adjusted, with the most commonly used vertical orientation of the swing arm 07th Easy to ensure over a clearly noticeable during the pivoting locking arrangement or reproduce with sufficiently good accuracy.
- the currently effective pivot angle w 0 °.
- FIG. 3 shows the digital microscope according to FIG. 1 with a swivel arm 07 pivoted at an angle w2.
- FIG. 4 shows a vector illustration of the geometric relationships between an ideal swivel axis 26 and the swivel axis 04 in the calibration operation according to the invention.
- Vectors marked with an overline the amounts of the vectors bear the same designations as the vectors, but without overline.
- Direction information relative to the representation contains.
- a negative sign of such a one-dimensional variable in the calculation path corresponds in FIG. 4 to the exchange of the
- the position of the pivot axis 04 relative to the ideal pivot axis 26 or the object detail 13 is determined by the vector MI described.
- This vector can also be decomposed into the vectors MIX and MIZ arranged parallel to the coordinate axes, the vector MIZ ending at the point MAZ and the vector MIX beginning at the point MAZ. The not in Figure 4
- a L between the object plane and the end face 22 of the lens 12 in the vertical adjustment of the pivot arm 07 can be described by a corresponding vector AL, which is also not shown in Figure 4 for reasons of clarity.
- the vector AL can be decomposed into the vector MIZ and the vector A.
- the vectors rotate correspondingly about the pivot axis 04.
- the vector MIX the vector MIX from the vector MIZ the vector MIZ from the vector A the vector A from the vector AL the vector AL ⁇ and from the point MAZ the point MAZ ⁇ .
- the object plane OE is pivoted about the pivot axis 04, so that therefrom a
- pivoted object plane OE ⁇ results.
- the vectors ⁇ ⁇ and ⁇ ⁇ lie on the tilted optical axis ⁇ ⁇ .
- Piercing point 27 of the tilted optical axis ⁇ ⁇ through the tilted object plane OE ⁇ ends the vector dF, which is a measure of the defocusing and begins at the laterally offset object detail OD ⁇ .
- MIX MIX '
- MIX + MIZ dx + dF + MIZ '+ MIX' / -MIZ * sin (w2) + V MIZ * cos (w2), after transformation this results in: sin (w2)
- MIX 0.5 * dx - 0.5 * dF *
- MIZ -0.5 * dF + 0.5 * dx *
- control and display unit can be integrated, for example, in the control and display unit, thus be assumed to be known. All calculated data can be stored in the control unit and used further if necessary.
- FIGS. 5 and 6 show illustrations of the front view of the swivel arm 07 pivoted about the swivel angle w2 using the calibration method according to the invention.
- MIX and MIZ is the location of
- Swivel arm 07 is sharply displayed in the correction operation according to the invention.
- Reference position Z Ro automatically positioned over the control device, so that the object detail 13 at each currently effective pivot angle w K after the correction according to the invention is arranged in the middle of the picture and is shown focused.
- a reference mark which is preferably a component of the surface 21 of the reflected-light insert plate 20 or the upper side of the upper tabletop 19, is used.
- a special calibration object which contains the reference mark and which can be reproducibly placed on the surface 21 of the incident light insert plate 20.
- Fig. 7 shows the initial state before the acquisition of the required data for the calibration.
- the object detail 13 is preferably transmitted by the user via the
- the focus can be carried out automatically via an autofocus system, which is not explained in detail here.
- MIX 0.5 * dx-0.5 * dF *
- MIZ -0.5 * dF + 0.5 * dx *
- (Motorized) object table 18 are moved over the (motorized) lower Z-guide 16 upwards, so that the observed object detail 13 is arranged at the height of the pivot axis 04.
- FIG. 8 shows the initial state after the acquisition of the required data according to the description of FIG. 7 before the automatic focus and table tracking.
- the object table 18 has been moved over the lower Z-guide 16 by the amount of the size DZ upwards, so that the observed object detail 13 is arranged at the height of the pivot axis 04.
- a second Z position Z u2 results relative to the reference position Z Ru of the lower Z guide 16.
- the Z position of the (motorized) upper Z-guide 08 must also be moved upward in order for the object detail 13 to continue to move in the Object level is arranged. According to FIG. 8, this results in a fifth Z position Z o5 relative to the reference position Z Ro of the upper Z guide 08.
- the focus position of the objective 12 used for the calibration during focusing is also positioned at the height of the pivot axis 04
- the position of the pivot axis 04 can be determined even after switching the system off and on again due to the given sufficiently good absolute positioning accuracy reproduce with sufficient accuracy.
- the position of the pivot axis 04 with the Z position Z Ru is clearly described, since this Z reference position of the motorized lower guide 16 describes the position of the surface 21 of the incident light insert plate 20, which serves as object support, relative to the pivot axis 04 and for each pan stand 01 remains individually constant.
- the focal position for focusing on the at the height of the factory is preferably already factory to each lens that is to be supplied to a digital microscope copy Swivel axis 04 positioned object detail 13 approached and stored.
- the stored values are each unique to a lens
- the data obtained during the calibration process can be used for the automatic correction process according to the invention, which can now be determined from the
- this time gain can be further increased if the object detail 13 to be observed is already arranged automatically in the vertical position of the swivel arm 07 at the height of the swivel axis 04.
- FIGS 9 and 10 show illustrations for
- the ideal pivot axis 26 may also lie above the pivot axis 04, with the lower one driven all the way down
- FIG. 11 shows an illustration of the calibration steps S1 to S18 according to the invention, which are preferably to be carried out in the factory before the delivery of the digital microscope system to the customer or the user in a first calibration operation in order to simplify the customer's operation and the user with regard to the required
- the calibration process can also be carried out by the customer, provided the user interface is prepared for this. Then, the operation should still be aligned to a factory calibration, so that a customer feasible calibration to minimize accidental calls to this functionality is only indirectly accessible.
- FIG. 12 to 14 show illustrations of
- Steps according to the invention which are provided in the customer's use of the swivel function and are based on an already performed Clearkalibriervorgang according to Figure 11 and the foregoing description.
- the calibration processes take place via
- An automatic correction can be provided via the use of the probe signal or only after
- controller provides a factory reset.
- Adjustment length of the lens used (advantageous assignment via coding of the lenses) and use of the stored factory default Z position of the motorized upper Z axis for automatic access of the object details in the pivot axis possible.
- This can optionally be selected via a Button and / or be provided on activation of the button.
- All of the aforementioned embodiments relate to an optical axis (OA) of the imaging system, via which an object detail (13) arranged therein and in the object plane is always imaged independently of other influences in the center of the image.
- OA optical axis
- the remaining inaccuracies of the imaging system can practically result in that there is a deviating from the center of the image zoom center, which is maintained stationary with a change in the zoom factor in the image.
- This then still corresponds to the position of the optical axis (OA), d. H.
- the calibration and correction processes according to the invention would then have to relate to this zoom center in the image and not to the center of the image.
- the object detail (13) would then have to be positioned in each case on a target mark in the image, which is located in the zoom center and not in the center of the image.
- the term "centering the calibration mark with the optical axis (OA)" also includes this case.
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- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Optics & Photonics (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Mechanical Engineering (AREA)
- Multimedia (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Microscoopes, Condenser (AREA)
- Mounting And Adjusting Of Optical Elements (AREA)
- Studio Devices (AREA)
Abstract
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102013222295.5A DE102013222295A1 (de) | 2013-11-04 | 2013-11-04 | Digitalmikroskop, Verfahren zur Kalibrierung und Verfahren zur automatischen Fokus- und Bildmittennachführung für ein solches Digitalmikroskop |
PCT/EP2014/073039 WO2015063047A1 (de) | 2013-11-04 | 2014-10-28 | Digitalmikroskop mit schwenkstativ, verfahren zur kalibrierung und verfahren zur automatischen fokus- und bildmittennachführung für ein solches digitalmikroskop |
Publications (1)
Publication Number | Publication Date |
---|---|
EP3066510A1 true EP3066510A1 (de) | 2016-09-14 |
Family
ID=51842514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP14790577.2A Ceased EP3066510A1 (de) | 2013-11-04 | 2014-10-28 | Digitalmikroskop mit schwenkstativ, verfahren zur kalibrierung und verfahren zur automatischen fokus- und bildmittennachführung für ein solches digitalmikroskop |
Country Status (6)
Country | Link |
---|---|
US (1) | US9817223B2 (de) |
EP (1) | EP3066510A1 (de) |
JP (1) | JP6510502B2 (de) |
CN (1) | CN105683802B (de) |
DE (1) | DE102013222295A1 (de) |
WO (1) | WO2015063047A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
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KR101816886B1 (ko) | 2014-10-22 | 2018-01-09 | 사회복지법인 삼성생명공익재단 | 호흡 유도 시스템 및 방법 |
US10514532B1 (en) | 2015-09-27 | 2019-12-24 | Caliber Imaging & Diagnostics, Inc. | Confocal microscope having a positionable imaging head mounted on a boom stand |
CN105511051B (zh) * | 2016-01-18 | 2018-02-27 | 杭州瑞杰珑科技有限公司 | 一种快速对焦的折叠式助视器 |
JP6800698B2 (ja) * | 2016-10-21 | 2020-12-16 | 株式会社キーエンス | 拡大観察装置および拡大観察装置の制御方法 |
CN110268299A (zh) * | 2016-11-12 | 2019-09-20 | 凯利博成像和诊断公司 | 带有可定位成像头的共焦显微镜 |
DE102017114562A1 (de) | 2017-06-29 | 2019-01-03 | Carl Zeiss Microscopy Gmbh | Mikroskop und Verfahren zum Mikroskopieren einer Probe unter einem veränderbaren mechanischen Parameter |
RU181208U1 (ru) * | 2018-01-09 | 2018-07-06 | федеральное государственное бюджетное образовательное учреждение высшего образования "Башкирский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Устройство для цифровой микроскопии |
EP3514594A1 (de) * | 2018-01-19 | 2019-07-24 | Leica Instruments (Singapore) Pte. Ltd. | Verfahren zum automatisierten ausrichten eines stativs für ein mikroskop, stativ für ein mikroskop und mikroskopanordnung |
EP3759540A4 (de) | 2018-02-26 | 2022-03-16 | Caliber Imaging & Diagnostics, Inc. | System und verfahren zur makroskopischen und mikroskopischen abbildung von ex-vivo-gewebe |
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- 2014-10-28 WO PCT/EP2014/073039 patent/WO2015063047A1/de active Application Filing
- 2014-10-28 JP JP2016518203A patent/JP6510502B2/ja active Active
- 2014-10-28 US US15/021,809 patent/US9817223B2/en active Active
- 2014-10-28 CN CN201480060489.XA patent/CN105683802B/zh active Active
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WO2015063047A1 (de) | 2015-05-07 |
US20160231552A1 (en) | 2016-08-11 |
DE102013222295A1 (de) | 2015-05-07 |
CN105683802A (zh) | 2016-06-15 |
CN105683802B (zh) | 2018-06-22 |
JP2016538581A (ja) | 2016-12-08 |
US9817223B2 (en) | 2017-11-14 |
JP6510502B2 (ja) | 2019-05-08 |
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