EP2480896A4 - INTEGRATED CARTRIDGE - Google Patents

INTEGRATED CARTRIDGE

Info

Publication number
EP2480896A4
EP2480896A4 EP10817589.4A EP10817589A EP2480896A4 EP 2480896 A4 EP2480896 A4 EP 2480896A4 EP 10817589 A EP10817589 A EP 10817589A EP 2480896 A4 EP2480896 A4 EP 2480896A4
Authority
EP
European Patent Office
Prior art keywords
integrated cartridge
cartridge
integrated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10817589.4A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2480896A2 (en
Inventor
Phillip Belgrader
Christopher G Cooney
Aleksandr N Perov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akonni Biosystems Inc
Original Assignee
Akonni Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akonni Biosystems Inc filed Critical Akonni Biosystems Inc
Publication of EP2480896A2 publication Critical patent/EP2480896A2/en
Publication of EP2480896A4 publication Critical patent/EP2480896A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
EP10817589.4A 2009-09-21 2010-09-20 INTEGRATED CARTRIDGE Withdrawn EP2480896A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27239709P 2009-09-21 2009-09-21
PCT/US2010/002568 WO2011034620A2 (en) 2009-09-21 2010-09-20 Integrated cartridge

Publications (2)

Publication Number Publication Date
EP2480896A2 EP2480896A2 (en) 2012-08-01
EP2480896A4 true EP2480896A4 (en) 2015-12-02

Family

ID=43757137

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10817589.4A Withdrawn EP2480896A4 (en) 2009-09-21 2010-09-20 INTEGRATED CARTRIDGE

Country Status (8)

Country Link
US (2) US8623789B2 (xx)
EP (1) EP2480896A4 (xx)
JP (4) JP5671540B2 (xx)
CN (2) CN102667489B (xx)
CA (1) CA2811888A1 (xx)
HK (1) HK1175843A1 (xx)
IN (1) IN2012DN03430A (xx)
WO (1) WO2011034620A2 (xx)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10300482B2 (en) * 2010-12-09 2019-05-28 Akonni Biosystems, Inc. Sample analysis system
US10125388B2 (en) 2007-10-31 2018-11-13 Akonni Biosystems, Inc. Integrated sample processing system
US9791386B2 (en) * 2009-01-20 2017-10-17 Spectro Scientific, Inc. Integrated, portable sample analysis system and method
ITTO20100068U1 (it) * 2010-04-20 2011-10-21 Eltek Spa Dispositivi microfluidici e/o attrezzature per dispositivi microfluidici
CA2870069C (en) * 2011-04-13 2021-07-20 Akonni Biosystems, Inc. Microarray based sample detection system
JP5892589B2 (ja) * 2011-11-24 2016-03-23 マイクロ化学技研株式会社 マイクロデバイス及びバイオアッセイシステム
US9725687B2 (en) 2011-12-09 2017-08-08 President And Fellows Of Harvard College Integrated human organ-on-chip microphysiological systems
EP2812344A4 (en) 2012-02-07 2015-10-28 Vibrant Holdings Llc SUBSTRATE, PEPTIDARRAYS AND METHOD
NL2008737C2 (nl) 2012-05-01 2013-11-04 Consultatie Implementatie Tech Beheer B V Afsluitelement voor het afsluiten van een houder voor monsters.
KR102041217B1 (ko) * 2012-05-30 2019-11-07 주식회사 미코바이오메드 다-채널 하향 액체 주입 장치, 이를 포함하는 핵산 추출 장치, 및 이를 이용한 핵산 추출 방법
JP6227638B2 (ja) * 2012-07-03 2017-11-08 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ サンプル調製装置
US10006909B2 (en) 2012-09-28 2018-06-26 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
JP2015531486A (ja) * 2012-09-28 2015-11-02 ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー 生体分子解析のための方法、システム、およびアレイ
DE102012109317A1 (de) * 2012-10-01 2014-04-03 Astrium Gmbh Vorrichtung zur Durchführung einer biochemischen Analyse, insbesondere im Weltraum
US10286376B2 (en) 2012-11-14 2019-05-14 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
WO2014127328A2 (en) 2013-02-15 2014-08-21 Vibrant Holdings, Llc. Methods and compositions for amplified electrochemiluminescence detection
US9535082B2 (en) 2013-03-13 2017-01-03 Abbott Laboratories Methods and apparatus to agitate a liquid
USD978375S1 (en) 2013-03-13 2023-02-14 Abbott Laboratories Reagent container
US10058866B2 (en) 2013-03-13 2018-08-28 Abbott Laboratories Methods and apparatus to mitigate bubble formation in a liquid
USD962471S1 (en) 2013-03-13 2022-08-30 Abbott Laboratories Reagent container
WO2014189624A1 (en) * 2013-05-20 2014-11-27 Silicon Biodevices, Inc. Digital control of on-chip magnetic particle assay
JP6178161B2 (ja) * 2013-08-21 2017-08-09 株式会社日立ハイテクノロジーズ フローセル固定装置及び核酸分析装置
US9568404B2 (en) 2014-05-16 2017-02-14 Junyu Mai Method and apparatus for biomolecule analysis
EP2950076B1 (en) * 2014-05-26 2017-06-28 CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement Portable system for automated preparation of liquid and/or solid samples
EP3151965B1 (en) 2014-06-04 2021-02-24 Edan Instruments, Inc. Sample collection and analysis devices
US10081016B2 (en) 2014-06-19 2018-09-25 Akonni Biosystems, Inc. Molecular analysis system and use thereof
CN107109701B (zh) * 2014-09-16 2020-10-09 斯坦福国际研究院 通过光纤阵列扫描技术发现亲和试剂和催化剂
US9885352B2 (en) 2014-11-25 2018-02-06 Genia Technologies, Inc. Selectable valve of a delivery system
USD815752S1 (en) * 2014-11-28 2018-04-17 Randox Laboratories Ltd. Biochip well
US11377651B2 (en) * 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
CA2987633A1 (en) 2015-06-02 2016-12-08 Biofire Defense, Llc Sample to sequence
EP3349899A4 (en) * 2015-09-14 2019-03-27 Singulex, Inc. SINGLE MOLECULE DETECTION ON A CHIP
CN105301267A (zh) * 2015-11-16 2016-02-03 常州大学 一种烟煤灼烧物自动过滤清洗的操作端转动齿传设备
CN105733927A (zh) * 2016-04-11 2016-07-06 广州市达安医疗器械有限公司 一种用于核酸提取的耗材及多联耗材
EP3301431B1 (en) 2016-09-29 2019-08-28 Roche Diagniostics GmbH Multi-chamber analysis device and method for analyzing
US11440013B2 (en) * 2016-09-30 2022-09-13 Koninklijke Philips N.V. System for preparing a sample
GB201704768D0 (en) * 2017-01-05 2017-05-10 Illumina Inc Flow cell liquid degassing systema and method
DE102017206155A1 (de) * 2017-04-11 2018-10-11 Robert Bosch Gmbh Desorption von Nukleinsäuren
EP3611508B1 (en) * 2017-05-16 2022-08-03 SK Telecom Co., Ltd. Nucleic acid analysis apparatus using catridge
US10538808B2 (en) 2017-05-26 2020-01-21 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
CN107192714B (zh) * 2017-06-01 2020-03-27 首钢集团有限公司 一种测量浸入式水口堵塞程度的方法及系统
WO2019043779A1 (ja) * 2017-08-29 2019-03-07 横河電機株式会社 核酸抽出方法および核酸抽出装置
KR102043502B1 (ko) * 2017-09-04 2019-11-11 한국과학기술원 바이옵시 장치
CN107385103B (zh) * 2017-09-18 2023-04-07 星源智（珠海）生物科技有限公司 一种非纯化核酸扩增方法及装置
CN107727425A (zh) * 2017-10-25 2018-02-23 哈尔滨师范大学 一种小型哺乳动物代谢物收集分析器
US11511278B2 (en) 2017-12-28 2022-11-29 Stmicroelectronics S.R.L. Solid reagent containment unit, in particular for a portable microfluidic device for sample preparation and molecule analysis
US11110457B2 (en) 2017-12-28 2021-09-07 Stmicroelectronics S.R.L. Analysis unit for a transportable microfluidic device, in particular for sample preparation and molecule analysis
US11717825B2 (en) 2017-12-28 2023-08-08 Stmicroelectronics S.R.L. Magnetically controllable valve and portable microfluidic device having a magnetically controllable valve, in particular cartridge for sample preparation and molecule analysis
US11278897B2 (en) 2017-12-28 2022-03-22 Stmicroelectronics S.R.L. Cartridge for sample preparation and molecule analysis, cartridge control machine, sample preparation system and method using the cartridge
US11491489B2 (en) 2017-12-28 2022-11-08 Stmicroelectronics S.R.L. Microfluidic connector group, microfluidic device and manufacturing process thereof, in particular for a cartridge for sample preparation and molecule analysis
CN111249946A (zh) * 2018-04-28 2020-06-09 王书华 一种可搅拌试剂盒
CN108796038B (zh) * 2018-06-26 2019-10-18 杭州优思达生物技术有限公司 一种核酸一体化检测方法及检测试剂管
CN109112060B (zh) * 2018-09-13 2021-09-14 青岛大学附属医院 一种微生物样本涂片笔
CN109647552B (zh) * 2018-12-27 2021-09-28 南京祥中生物科技有限公司 集成式的微阵列生物芯片及识别方法
WO2021081472A1 (en) * 2019-10-25 2021-04-29 Fabrico Technology Inc Systems and methods for measuring colorimetric reactions
US11408032B2 (en) * 2020-01-17 2022-08-09 Element Biosciences, Inc. Tube lens design for improved depth-of-field
JP7290345B2 (ja) * 2020-02-25 2023-06-13 Ｂｌｕｅ Ｉｎｄｕｓｔｒｉｅｓ株式会社 遺伝子解析用前処理キット、核酸分析用チップ、解析システム、生体物質分析用チップ
CN113528317A (zh) * 2020-04-15 2021-10-22 拓原合壹(宁波)生物技术有限公司 核酸提取方法
GB2594980A (en) * 2020-05-14 2021-11-17 Agilent Tech Lda Uk Limited Spectral analysis of a sample
US20220162585A1 (en) * 2020-11-23 2022-05-26 Frank Leo Spangler System and method of nucleic acid extraction
WO2022115722A2 (en) * 2020-11-30 2022-06-02 Nexogen, Inc. Microfluidic system based on active control of flow resistance in microfluidic channels and methods of use thereof
CN113416629B (zh) * 2021-06-03 2023-09-22 中南大学湘雅三医院 一种肿瘤化疗药物敏感性检测试剂盒和检测方法
TWI815219B (zh) * 2021-11-19 2023-09-11 台達電子工業股份有限公司 核酸處理裝置及其樣本前處理模組

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999001221A1 (de) * 1997-06-30 1999-01-14 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Mikroreaktionsgefäss, anordnung von mikroreaktionsgefässen sowie verfahren zur abgabe einer flüssigkeit aus den selben
US20080153078A1 (en) * 2006-06-15 2008-06-26 Braman Jeffrey C System for isolating biomolecules from a sample
WO2009049268A1 (en) * 2007-10-12 2009-04-16 Rheonix, Inc. Integrated microfluidic device and methods
US20090111193A1 (en) * 2007-10-31 2009-04-30 Cooney Christopher G Sample preparation device

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5230866A (en) * 1991-03-01 1993-07-27 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
US5305139A (en) * 1991-04-19 1994-04-19 Unimat (Usa) Corporation, Formerly United Holdings, Inc. Illumination system and method for a high definition 3-D light microscope
US5498392A (en) * 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
JP3326881B2 (ja) * 1993-06-25 2002-09-24 株式会社ニコン 走査型光学顕微鏡
RU2041262C1 (ru) 1993-08-11 1995-08-09 Институт молекулярной биологии им.В.А.Энгельгардта РАН Способ иммобилизации водорастворимых биоорганических соединений на капиллярно-пористый носитель
RU2041261C1 (ru) 1993-08-11 1995-08-09 Институт молекулярной биологии им.В.А.Энгельгардта РАН Способ изготовления матрицы для детектирования мисматчей
US5981734A (en) 1997-07-17 1999-11-09 University Of Chicago Methods for immobilizing nucleic acids on a gel substrate
JP4503716B2 (ja) * 1997-08-29 2010-07-14 オリンパス株式会社 顕微鏡透過照明装置
US6656725B2 (en) 2001-08-15 2003-12-02 The University Of Chicago Method of fabrication of microarray of gel-immobilized compounds on a chip by copolymerization
JP2006510872A (ja) * 2002-05-28 2006-03-30 オウトジエノミクス・インコーポレーテツド 統合された試料処理プラットフォーム
US7148057B2 (en) * 2002-08-13 2006-12-12 Gongin Precision Industries, Co., Ltd Array biochip workstation
EP1546721B2 (en) * 2002-08-16 2017-05-17 Avantra Biosciences Corporation Substrates for isolating, reacting and microscopically analyzing materials
JP2004078690A (ja) * 2002-08-20 2004-03-11 Olympus Corp 画像比較装置、画像比較方法および画像比較をコンピュータにて実行させるためのプログラム
US20060094108A1 (en) * 2002-12-20 2006-05-04 Karl Yoder Thermal cycler for microfluidic array assays
JP4198982B2 (ja) * 2002-12-26 2008-12-17 オリンパス株式会社 波長分離素子および顕微鏡
WO2004063731A1 (ja) * 2003-01-16 2004-07-29 Olympus Corporation 光検出装置
DE10315074A1 (de) * 2003-04-02 2004-10-14 Clondiag Chip Technologies Gmbh Vorrichtung zur Vervielfältigung und zum Nachweis von Nukleinsäuren
JP2004309426A (ja) * 2003-04-10 2004-11-04 Denso Corp 透光性基板の評価方法及び透光性基板の評価装置
JP4354207B2 (ja) * 2003-04-15 2009-10-28 オリンパス株式会社 顕微鏡装置
EP1508375A3 (en) * 2003-08-19 2006-04-05 Fuji Photo Film Co., Ltd. Rack for extracting apparatuses
JP4993653B2 (ja) * 2003-10-03 2012-08-08 キヤノン株式会社 記録材判別装置および画像形成装置並びにその方法
GB2431122B (en) * 2004-02-19 2009-06-10 Waters Investments Ltd Pin valve assembly
DE102004053730B4 (de) * 2004-11-06 2014-04-03 Carl Zeiss Jena Gmbh Verfahren und Anordnung zur Unterdrückung von Falschlicht
WO2007018760A2 (en) 2005-08-08 2007-02-15 The University Of Chicago Preparation of plastic supports for biochips
JP4632899B2 (ja) * 2005-08-17 2011-02-16 丸茂電機株式会社 Ｌｅｄスポットライト
JP4687413B2 (ja) * 2005-11-16 2011-05-25 コニカミノルタエムジー株式会社 マイクロチップにおける２種類以上の液体の混合方法およびマイクロ総合分析システム
JP2007171144A (ja) * 2005-12-26 2007-07-05 Toray Ind Inc カバーを有するマイクロアレイ
WO2007136715A2 (en) * 2006-05-16 2007-11-29 Arcxis Biotechnologies Pcr-free sample preparation and detection systems for high speed biologic analysis and identification
JP4909672B2 (ja) * 2006-08-08 2012-04-04 株式会社日本マイクロニクス 液晶パネル検査方法及び装置
JP2008180578A (ja) * 2007-01-24 2008-08-07 Toppan Printing Co Ltd 周期性パターンのムラ検査装置
JP4869129B2 (ja) * 2007-03-30 2012-02-08 Ｈｏｙａ株式会社 パターン欠陥検査方法
JP2009002899A (ja) * 2007-06-25 2009-01-08 Akita Prefecture 検出装置
US7955840B2 (en) 2007-08-23 2011-06-07 Akonni Biosystems Thermal cycler for PCR including temperature control bladder
US7955841B2 (en) 2007-08-23 2011-06-07 Akonni Biosystems Temperature control device with a flexible temperature control surface
WO2009054254A1 (ja) * 2007-10-26 2009-04-30 Konica Minolta Medical & Graphic, Inc. マイクロチップとそれを用いた検査装置
US7759112B2 (en) 2007-10-31 2010-07-20 Akonni Biosystems, Inc. Apparatus, system, and method for purifying nucleic acids
US8680025B2 (en) 2008-05-09 2014-03-25 Akonni Biosystems, Inc. Microarray system
RU2559541C2 (ru) * 2009-06-05 2015-08-10 Интедженкс Инк. Универсальная система подготовки образцов и применение в интегрированной системе анализа

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999001221A1 (de) * 1997-06-30 1999-01-14 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Mikroreaktionsgefäss, anordnung von mikroreaktionsgefässen sowie verfahren zur abgabe einer flüssigkeit aus den selben
US20080153078A1 (en) * 2006-06-15 2008-06-26 Braman Jeffrey C System for isolating biomolecules from a sample
WO2009049268A1 (en) * 2007-10-12 2009-04-16 Rheonix, Inc. Integrated microfluidic device and methods
US20090111193A1 (en) * 2007-10-31 2009-04-30 Cooney Christopher G Sample preparation device

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JP2015092175A (ja) 2015-05-14
JP2013505442A (ja) 2013-02-14
CA2811888A1 (en) 2011-03-24
US20110071055A1 (en) 2011-03-24
US9074245B2 (en) 2015-07-07
US20130079253A1 (en) 2013-03-28
US20120004143A2 (en) 2012-01-05
HK1175843A1 (zh) 2013-07-12
WO2011034620A3 (en) 2011-06-03
IN2012DN03430A (xx) 2015-10-23
CN105675496B (zh) 2019-07-05
JP2017029152A (ja) 2017-02-09
CN105675496A (zh) 2016-06-15
US8623789B2 (en) 2014-01-07
CN102667489A (zh) 2012-09-12
WO2011034620A2 (en) 2011-03-24
JP5671540B2 (ja) 2015-02-18
EP2480896A2 (en) 2012-08-01
JP2019002933A (ja) 2019-01-10
JP5993928B2 (ja) 2016-09-14
CN102667489B (zh) 2016-02-10
JP6370847B2 (ja) 2018-08-08

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