EP1998181A2 - Réservoir à liquides doté d'une cheminée variable - Google Patents

Réservoir à liquides doté d'une cheminée variable Download PDF

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Publication number
EP1998181A2
EP1998181A2 EP08009646A EP08009646A EP1998181A2 EP 1998181 A2 EP1998181 A2 EP 1998181A2 EP 08009646 A EP08009646 A EP 08009646A EP 08009646 A EP08009646 A EP 08009646A EP 1998181 A2 EP1998181 A2 EP 1998181A2
Authority
EP
European Patent Office
Prior art keywords
liquid
chimney
container
permeable zone
removal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP08009646A
Other languages
German (de)
English (en)
Other versions
EP1998181A3 (fr
EP1998181B1 (fr
EP1998181B8 (fr
Inventor
Gottfried Senftner
Markus Winkenbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Original Assignee
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG, Roche Diagnostics GmbH filed Critical F Hoffmann La Roche AG
Priority to EP08009646.4A priority Critical patent/EP1998181B8/fr
Publication of EP1998181A2 publication Critical patent/EP1998181A2/fr
Publication of EP1998181A3 publication Critical patent/EP1998181A3/fr
Publication of EP1998181B1 publication Critical patent/EP1998181B1/fr
Application granted granted Critical
Publication of EP1998181B8 publication Critical patent/EP1998181B8/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/08—Flasks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/523—Containers specially adapted for storing or dispensing a reagent with means for closing or opening
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3216—Rigid containers disposed one within the other
    • B65D81/3222—Rigid containers disposed one within the other with additional means facilitating admixture
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/049—Valves integrated in closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/065—Valves, specific forms thereof with moving parts sliding valves
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Definitions

  • the invention relates to a liquid container having an upper opening and extending into alignment with the upper opening in the container, tubular removal chute for liquid removal by means of a to be introduced from the top of the discharge chimney extraction element, in particular a pipette, wherein the removal chimney in its lower, the container bottom adjacent end region has a liquid-permeable zone.
  • the invention relates to liquid containers used as reagent liquid containers in automatic analyzers.
  • reagent liquid is taken from the liquid containers by automatic pipetting. This is done in a faster cycle in more modern systems to allow high throughput of relevant analysis operations.
  • the liquid container by means of a transport device, for example in the form of a rotor quickly supplied to the pipetting and braked there, whereupon the automatic pipette or suction needle through the upper opening of the liquid container passes into the extraction chimney to suck liquid.
  • a transport device for example in the form of a rotor quickly supplied to the pipetting and braked there, whereupon the automatic pipette or suction needle through the upper opening of the liquid container passes into the extraction chimney to suck liquid.
  • each individual pipetting operation including the positioning of the liquid container in the pipetting zone, has extremely short single-second cycle times.
  • the pipette tip during pipetting should also dip only slightly into the liquid to be pipetted and the level in the liquid container should be as calm as possible. It should also be avoided that the pipette draws air due to a fluctuating liquid level. Furthermore, foaming in the extraction chimney should be suppressed.
  • the state of the art of reaction liquid containers with removal chimney can, for example, on the WO 97/12677 A1 , on the US 5,102,631 or on the DE 38 38 278 C1 to get expelled.
  • the tubular discharge chimney is provided at its upper end with a radially outwardly projecting flange, with which it is suspended from a spout of the container opening.
  • the completely open lower end of the removal chimney extends into the vicinity of the bottom of the liquid container, so that liquid communication between the removal chimney and the surrounding interior region of the liquid container can only take place via a narrow bottom gap through the lower opening of the removal chimney.
  • slit-like wall thickness reductions are provided in the upper region of the extraction chimney, which are intended to allow an influx of air between the mouth of the liquid container and the mantle of the extraction chimney.
  • a liquid container with removal chimney is known in which the cross section of the removal chimney is substantially smaller than the cross section of the upper container opening, said removal chimney interspersing a screwed with the mouth grommet screw cap and is fixed on this.
  • a through hole in the screw cap allows pressure equalization between the container interior and the external environment.
  • the removal chimney extends into the vicinity of the container bottom, so that liquid exchange between the discharge chimney and the surrounding interior of the container can take place through the open underside of the removal chimney.
  • the outer circumference of the removal chimney at its upper end and the inner circumference of the discharge chimney surrounding at its upper end spout are only slightly different, so that between the outside of the extraction chimney and the inner surface of the spout not sufficiently large ventilation path for pressure equalization between the container interior and the environment remains.
  • a through hole in the jacket of the extraction chimney is provided at its upper end.
  • the removal chimney is substantially completely open at its lower end, with spacer webs being provided at the lower end of the withdrawal chimney.
  • the from the US 5,102,631 known liquid container is similar to the last-mentioned embodiment of the DE 38 38 278 C1 constructed and thus also has a through hole in the jacket of the discharge chimney at the upper end.
  • the extraction chimney extends to the bottom of the liquid container, but large lateral openings are provided in the jacket of the extraction chimney at the lower end.
  • the removal chimney According to the operating principle of the removal chimney, it is provided in the known examples that between the lower end of the removal chimney and the opposite container bottom only a small distance and thus only a narrow flow gap to form a large flow resistance is given, so that fluctuations in the container volume outside As far as possible, the discharge chimney can only have a damped effect in the withdrawal chimney.
  • the known extraction chimneys thus have at their end adjacent the container bottom end a liquid-permeable zone with a low fluid permeability on.
  • the invention has for its object to provide a liquid container of the type mentioned, which can be filled quickly through the upper opening and through the removal chimney and yet in the liquid removal operation, the desired properties of calming the liquid level within the extraction chimney against the fluctuations in the container area outside of the Removal chimney has.
  • the removal chimney and thus the liquid-permeable zone can be used e.g. be set so that their fluid permeability is relatively large.
  • the liquid-permeable zone can then be set back into a state with low liquid permeability, so that the removal chimney can fulfill its desired function in the liquid-removal operation of the liquid container.
  • the liquid permeability of the liquid-permeable zone is not completely suppressed in any of the settings of the extraction chimney. In the position of minimal liquid permeability, therefore, liquid exchange between the extraction chimney and the surrounding container body can take place.
  • the liquid-permeable zone comprises at least one opening in the lower end region of the extraction chimney whose effective opening cross-section is adjustable, this preferably by a rotary movement and / or lifting movement of the extraction chimney or a portion thereof relative to the liquid container bottom.
  • Lifting means and / or latching means and / or markers are preferably provided on the extraction chimney and / or on the container body to define the limit settings of the minimum liquid permeability and the larger liquid permeability of the liquid pervious zone.
  • the removal chimney has a pipe section extending downwardly from the upper tank opening and a pipe receiving means provided on the tank bottom for the pipe section, the pipe section and the pipe receiving one another plugged - and are adjustable relative to each other to change the effective opening cross-section of the liquid-permeable zone.
  • the invention include the liquid-permeable zone lateral openings in the pipe section and lateral openings in the pipe receiving in the lower end of the extraction chimney, wherein lateral openings of the pipe section and lateral openings of the pipe receiving relative to each other in common alignment are aligned to the effective opening cross-section of the liquid-permeable zone.
  • the change in the transmission capacity of the liquid-permeable zone is effected simply by bringing a pipe section of the extraction chimney extending from the upper container opening close to the container bottom closer to the container bottom, so that only a small flow gap between container bottom and lower end of the pipe section remains. This is then the condition of the lower fluid permeability of the liquid-permeable zone.
  • the liquid permeability of the liquid-permeable zone is then increased.
  • the removal chimney is securely received in the liquid container, so that it is not removable from the latter under normal handling conditions even when the liquid container is open.
  • the setting of the removal chimney in the position of greater fluid permeability can be done before the introduction of the liquid container in the automatic filling station or after. What is essential is that the normally automatic and fast filling step occurs while the discharge chimney is set in the position of greater liquid permeability of the liquid-permeable zone.
  • the liquid container according to the invention in which the liquid can be filled in a fast-cycling automatic filling station in high-throughput operation to prepare the liquid container for the subsequent provision of the liquid in a high-speed automatic analyzer, wherein the Fluid removal in the automatic analyzer by aspirating fluid from the fluid reservoir by means of a pipette or the like, while the extraction chimney is set in the position of minimum liquid permeability of the liquid-permeable zone. It is thus high-throughput operation in the automatic filling station and high-throughput operation in the automatic analyzer with the liquid container according to the invention possible, without having to accept disadvantages compared to the prior art of the generic liquid container in purchasing.
  • the vertical longitudinal section runs centrally through the discharge chimney 3 or 3a.
  • the liquid container 1 is a reagent liquid container which is used in the manner described in the beginning in automatic analyzers.
  • the liquid container 1 has at its upper end a screw cap opening 5, starting from which a pipe section 7 of the discharge chute 3 extends vertically into the container interior.
  • the container bottom 9 has a tube receptacle 11, which has a pot-like shape with two, for example, rectangular, open at the top incisions 13.
  • the incisions 13 are in the direction of the Fig. 1 a and 1 b in flight one behind the other on diametrically opposite sides of the tube receptacles eleventh
  • the pipe section 7 is received with its lower end in the pipe receptacle 11, in such a way that it lies with its outer circumference the inner periphery of the pipe receptacle 11 closely adjacent and preferably touching.
  • the tube holder 11 thus forms a pivot bearing for the pipe section 7 of the discharge chimney 3, so that the pipe section 7 is rotatable about the vertical axis of rotation 15 between two defined Drehanschlag tooen.
  • lateral cuts 17, which are provided at diametrically opposite regions of the pipe section 7 and do not extend beyond the uppermost edge of the pipe receptacle 11 also upward, are rotated relative to the notches 13 of the pipe receiving.
  • the cuts 17 and 13 represent lateral openings in the pipe section 7 and in the pipe receptacle 11 and together form a liquid-permeable zone 18 of the discharge chimney 3, whose effective opening cross-section depends on the extent to which the lateral openings 17 of the pipe section 7 in common alignment with the lateral openings 13 of the pipe receiving 11 are.
  • the lateral openings 17 of the tube section 7 are completely aligned with the lateral openings 13, so that the openings 13, 17 show a maximum overlap.
  • This is the limit position of the maximum effective opening cross-section of the liquid-permeable zone 18 of the discharge chimney 3, ie the defined setting of the larger liquid permeability of the liquid-permeable zone. It can take place in this situation, relatively good fluid exchange between the interior of the discharge chimney 3 and the container volume outside of the discharge chimney 3, which is responsible for filling the Liquid container 1 through the opening 5 and the discharge chimney 3 is important.
  • FIG. 1b shows the discharge chimney 3 in the limit of the minimum liquid transmittance of the zone 18 with a small effective opening cross-section of the liquid-permeable zone 18, as it is to be selected for the liquid extraction operation.
  • Rotary stops which prevent the tube section 7 from being turned beyond the limits shown, are in Fig. 1a and Fig. 1b Not shown.
  • the liquid passage capacity of the liquid-permeable zone 18 is varied by a lifting movement of the pipe section 7a relative to the vessel bottom 9.
  • the liquid-permeable zone is defined by the annular gap 19, while the discharge chimney pipe section 7a is raised Fig. 2a larger than when lowered extraction chimney pipe section 7a according to Fig. 2b and defined by the crenelated spaces 21.
  • Slings 20 and 22 ensure that defined end positions for the stroke adjustment of the pipe section 7a are possible, as this in the Fig. 2a and 2b can be seen.
  • Fig. 2a shows a provided for filling the container 1 limit setting of the removal chimney 3a.
  • Fig. 2b shows the favorable for the liquid extraction operation limit position of the discharge chimney 3a.
  • fluid exchange through zone 18 may occur.
  • a variant of the second embodiment with a modification of the lower end of the pipe section 7a is in the Fig. 3a and 3b shown.
  • Fig. 3a and 3b has the pipe section 7a at its lower end four spacer webs 22, which ensure that in the lowered state of the pipe section 7a according to Fig. 3b this with its lower edge not occlusive on the floor 9 auffirmden and also on the pipe section circumference circumferential collar 24 maintains a distance to the vessel bottom 9, so that the liquid-permeable zone 18 in Fig. 3b With reduced fluid permeability, fluid communication between the interior of the withdrawal chimney 3a and the container volume outside the withdrawal chimney can take place.
  • Fig. 3a shows a provided for filling the container 1 setting the removal chimney 3a.
  • Fig. 3b shows the favorable for the liquid removal operation position of the removal chimney 3a.
  • the extraction chimney can e.g. be adjustable by a combined lifting and turning movement. This may in particular be a screwing movement of the removal chimney.
  • the extraction chimney can in particular already be mounted therein before the filling of the liquid container.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
  • Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Extraction Or Liquid Replacement (AREA)
EP08009646.4A 2007-05-31 2008-05-27 Réservoir à liquides doté d'une cheminée variable Active EP1998181B8 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP08009646.4A EP1998181B8 (fr) 2007-05-31 2008-05-27 Réservoir à liquides doté d'une cheminée variable

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07010826A EP1998180A1 (fr) 2007-05-31 2007-05-31 Réservoir à liquides doté d'un cheminée variable
EP08009646.4A EP1998181B8 (fr) 2007-05-31 2008-05-27 Réservoir à liquides doté d'une cheminée variable

Publications (4)

Publication Number Publication Date
EP1998181A2 true EP1998181A2 (fr) 2008-12-03
EP1998181A3 EP1998181A3 (fr) 2011-02-23
EP1998181B1 EP1998181B1 (fr) 2019-06-19
EP1998181B8 EP1998181B8 (fr) 2019-09-11

Family

ID=38657241

Family Applications (2)

Application Number Title Priority Date Filing Date
EP07010826A Withdrawn EP1998180A1 (fr) 2007-05-31 2007-05-31 Réservoir à liquides doté d'un cheminée variable
EP08009646.4A Active EP1998181B8 (fr) 2007-05-31 2008-05-27 Réservoir à liquides doté d'une cheminée variable

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP07010826A Withdrawn EP1998180A1 (fr) 2007-05-31 2007-05-31 Réservoir à liquides doté d'un cheminée variable

Country Status (7)

Country Link
US (2) US8003053B2 (fr)
EP (2) EP1998180A1 (fr)
JP (1) JP5075018B2 (fr)
CN (1) CN101314142B (fr)
CA (1) CA2632622C (fr)
ES (1) ES2742511T3 (fr)
HK (1) HK1126157A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120048863A1 (en) * 2009-05-27 2012-03-01 Kids-Kit Cooperative Society Ltd. Child's cup
JP5242537B2 (ja) * 2009-11-06 2013-07-24 株式会社日立ハイテクノロジーズ 試薬容器、および試薬容器用管体
JP5292325B2 (ja) * 2010-01-28 2013-09-18 株式会社日立ハイテクノロジーズ 試薬容器
AU2013202778A1 (en) 2013-03-14 2014-10-02 Gen-Probe Incorporated Systems, methods, and apparatuses for performing automated reagent-based assays
EP3066478B1 (fr) 2013-11-05 2019-12-18 Siemens Healthcare Diagnostics Inc. Tube anti-évaporation de récipient de réactif
IES86617B2 (en) * 2014-05-27 2016-01-27 Beckman Coulter Inc Reagent bottle with aspiration pipe
US9783358B2 (en) * 2015-01-08 2017-10-10 Rajiv Dhand Segmented yogurt container
EP3097978B1 (fr) * 2015-05-27 2018-03-28 Siemens Healthcare Diagnostics Products GmbH Récipient de liquide doté d'un dispositif anticlapotis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3838278C1 (en) 1988-11-11 1990-01-18 Eppendorf - Netheler - Hinz Gmbh, 2000 Hamburg, De Reagent dispensing vessel
US5102631A (en) 1989-12-18 1992-04-07 Abbott Laboratories Evaporation chimney
WO1997012677A1 (fr) 1995-10-02 1997-04-10 Boehringer Mannheim Gmbh Recipients pour liquides

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US3139121A (en) * 1961-03-29 1964-06-30 Dosamatic Dropper Corp Liquid dispensing container
JPH0535099Y2 (fr) * 1986-07-04 1993-09-06
JPH09297146A (ja) * 1996-05-02 1997-11-18 Toa Medical Electronics Co Ltd 液体吸引装置
US5980834A (en) * 1996-07-25 1999-11-09 The United States Of America As Represented By The Secretary Of Commerce Sample storage devices
US6435383B1 (en) * 1998-07-15 2002-08-20 Jung-Min Lee Spout assembly for liquid container
US6959615B2 (en) * 1999-03-05 2005-11-01 Gamble Kimberly R Sample collection and processing device
JP2001322660A (ja) * 2000-05-17 2001-11-20 Yoshida Industry Co Ltd 吐出量調整用中栓
JP2002019855A (ja) * 2000-07-04 2002-01-23 Olympus Optical Co Ltd アダプターおよびアダプター付き容器
US6890484B2 (en) * 2001-05-18 2005-05-10 Acon Laboratories, Inc. In line test device and methods of use
US6726879B2 (en) * 2001-05-21 2004-04-27 Ameditech, Inc. Dual chambered fluid specimen testing device and method
AUPS290502A0 (en) * 2002-06-12 2002-07-04 Gannon, Glen Charles A drink container for combining a powder with a liquid
JP4020843B2 (ja) * 2003-09-05 2007-12-12 株式会社日立ハイテクノロジーズ 分析装置及び試薬容器
US20060286004A1 (en) * 2005-06-15 2006-12-21 Jacobs Merrit N Containers for reducing or eliminating foaming

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3838278C1 (en) 1988-11-11 1990-01-18 Eppendorf - Netheler - Hinz Gmbh, 2000 Hamburg, De Reagent dispensing vessel
US5102631A (en) 1989-12-18 1992-04-07 Abbott Laboratories Evaporation chimney
WO1997012677A1 (fr) 1995-10-02 1997-04-10 Boehringer Mannheim Gmbh Recipients pour liquides

Also Published As

Publication number Publication date
CN101314142A (zh) 2008-12-03
US8003053B2 (en) 2011-08-23
JP2008298779A (ja) 2008-12-11
ES2742511T3 (es) 2020-02-14
CN101314142B (zh) 2011-04-06
US20080299011A1 (en) 2008-12-04
EP1998181A3 (fr) 2011-02-23
CA2632622A1 (fr) 2008-11-30
EP1998181B1 (fr) 2019-06-19
JP5075018B2 (ja) 2012-11-14
US8153086B2 (en) 2012-04-10
CA2632622C (fr) 2011-04-26
US20110263039A1 (en) 2011-10-27
HK1126157A1 (en) 2009-08-28
EP1998180A1 (fr) 2008-12-03
EP1998181B8 (fr) 2019-09-11

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