EP1981637B1 - Procédé de fabrication d'un récipient d'échantillonnage servant à contenir de petites quantités de liquide pour analyses - Google Patents

Procédé de fabrication d'un récipient d'échantillonnage servant à contenir de petites quantités de liquide pour analyses Download PDF

Info

Publication number
EP1981637B1
EP1981637B1 EP07702363A EP07702363A EP1981637B1 EP 1981637 B1 EP1981637 B1 EP 1981637B1 EP 07702363 A EP07702363 A EP 07702363A EP 07702363 A EP07702363 A EP 07702363A EP 1981637 B1 EP1981637 B1 EP 1981637B1
Authority
EP
European Patent Office
Prior art keywords
cap
sample
membrane
liquid
analyses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP07702363A
Other languages
German (de)
English (en)
Other versions
EP1981637A1 (fr
Inventor
Walter Sarstedt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sarstedt AG and Co KG
Original Assignee
Sarstedt AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sarstedt AG and Co KG filed Critical Sarstedt AG and Co KG
Priority to PL07702363T priority Critical patent/PL1981637T3/pl
Publication of EP1981637A1 publication Critical patent/EP1981637A1/fr
Application granted granted Critical
Publication of EP1981637B1 publication Critical patent/EP1981637B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes

Definitions

  • the invention relates to a method for producing a sample vessel for receiving small quantities of liquid for analysis, comprising a closed at its one end tube and the other, open end sealingly occlusive, by a pierceable from a tip of a withdrawal cannula, a membrane disc having cap the membrane disc is inserted from below into the cap and supported by the inner surface of an outer flat, flat top wall of the cap as supported by the EP 1 211 184 A1 known.
  • a disc inserted or mounted from below into a closure cap of a vessel is likewise known from US Pat JP 7 075 663 A known.
  • the caps closing the open end are all pierceable sealing plugs, which extend with a cylindrical sealing portion into the open end of the tube and are sealed against the inner wall of the tube. They are suitable for the fully automatic removal of analysis samples, for which within the closure stopper a top-mounted, pierceable by the tip of a sampling cannula, made of rubber / rubber or an elastomeric plastic insert is disposed within the sealing plug.
  • This use of the sealing plug which consists of a completely elastically re-deforming material, is readily pierceable for the removal cannula of the analyzer, whereby the temporarily formed The piercing opening completely closes again after pulling out the cannula.
  • the occlusion device occluding the open end of the sample vessel, in particular blood sample tubes, comprises a stopper cap with a special top-mounted sealing stopper.
  • a retaining ring or a lock washer is mounted in this from the outer, free end side.
  • sample tags should be attached in such a way that it is visible even if many sample containers are stored tightly in a rack for storage.
  • the closed systems of the prior art are used, for example, for the field of blood collection or blood collection and comprise primary vessels which receive large quantities of blood, at least 2 ml and usually much more. In the case of direct adaptation, small sample volumes of a few ⁇ l are taken from the closed system. In these primary vessels, it is also already known to provide for these screw closures with pierceable and resealable membrane (see. DE 30 49 503 C ).
  • the extraction tube at its front end cap has a cylindrical, axially projecting dome, which has a top-mounted pierceable sealing stopper which rests on a provided with a central bore end plate of the dome and is held by a flanged collar.
  • this supernatant rules out that the lid surface can be provided with a labeling or sample identification.
  • the invention is therefore an object of the invention to provide a method of the type mentioned above, which allows for simple production and handling even with no liquid quantities a closed system and at the same time a visible sample identification.
  • the membrane disc is held supported by a flanged by hot deformation edge of the inner collar of the cap. It is hereby a suitable for commercial sample vessels closure with positionally secure seat or support and support of the membrane disc achieved that can be run as a screw or Stopfkappenver gleich, and in which the cap or headboard outer surface is always fully unrestricted available to without impairment, as is inevitable in the case of the usual from the top inserted into a correspondingly large opening membrane discs, to be provided with a label, a film or the like.
  • the insertable from below or inside, pierceable membrane disc is accessible from the outside, optionally via a small diameter piercing Duchgangsö réelle, unhindered for a sampling cannula, which allows a simple sample and Reagenzein- or output, with a repeated repetition of a Removal process, the membrane disc can not be pushed out of the closure. Because this is securely held in its position by their supported by the hot edge deformation of the end edge of the inner collar flanged edge of the cap supported.
  • This position-secure seat or the support and support of the membrane disk can be achieved, for example, by an inwardly beaded edge of an inner collar of the closure cap and / or a perforated disk inserted into and held by the inner collar supporting the membrane disk.
  • the membrane disc advantageously made of rubber, can not be pushed down out of the inner collar.
  • the flanging can be advantageously produced by hot deformation of the end edge of the inner collar.
  • An advantageous embodiment of the invention provides that the top wall of the closure cap is formed with a plastic membrane covering a piercing passage opening of the top wall of the closure cap. In this embodiment, too, there is a flat, flat, for a sample identification unreservedly full-surface outer surface of the cap before and is provided by the thin film at the same time with a contamination protection.
  • sample vessel 1 consists of a closed at its lower end from the outset tube 2 for receiving small amounts of liquid. At its upper end, the tube 2 is temporarily closed by a sealingly screw-on cap 3 - hereinafter referred to as a screw cap closure - closed.
  • the sortedkappenver gleich 3 has an inner collar 4 and concentric to this in its top wall 5 a small sized piercing passage opening 6. From inside or below is in the erkrappenverschluß 3 in the inner collar 4 with contact with the inner surface of the top wall 5 Vietnamesestechbare membrane disc. 7 used. This is held securely in its installed position by a flanged by hot deformation edge 8 of the inner collar 4.
  • a sealing bead can be provided, which ensures a liquid-tight fit of the closure, even in the event of a slight slight overpressure, e.g. by adding reagents can be ensured.
  • O-rings, sealing lips, sealing washers or the like it is possible by using e.g. O-rings, sealing lips, sealing washers or the like to achieve a liquid-tight closure.
  • the in Fig. 2 illustrated sterkappenverschluß 3 differs from the above-described embodiment in that the piercing through hole 6 is covered by a thin plastic membrane 10, which has only film thickness and, for example, is 0.1 mm.
  • the screw cap closures 3 have in common that they close a tube 2 for small amount of sample, which does not need to be opened for the repeated removal of a part or a subset of the sample or for the multiple addition of reagents.
  • the installation position of the highly elastic, resilient, easily penetrated by a cannula membrane disc 7 is not leaking even with repeated insertion and withdrawal of a cannula or sampling needle, and the membrane disc 7 can not be pushed out of the fferkappenver gleich 3.
  • the membrane plate 7 from below a flat, flat outside of the head wall and thus always a sufficiently large area for unobstructed attachment of a sample marking available. This also in the execution of the screw cap closure with a piercing passage opening, which can be covered by a plastic membrane. '

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Closures For Containers (AREA)

Claims (1)

  1. Procédé de fabrication d'un récipient à échantillon (1) pour recevoir de petites quantités de liquide pour des analyses, comprenant un petit tube (2) fermé sur l'une de ses extrémités, et un bouchon de fermeture (3) fermant de manière étanche l'autre extrémité ouverte, pouvant être traversé par la pointe d'une canule de prélèvement, présentant un disque membrane (7), sachant que le disque membrane (7) est introduit par le bas dans le bouchon de fermeture (3) et est appuyé en reposant sur la face intérieure d'une paroi de tête (5) plane et plate extérieure du bouchon de fermeture (3),
    caractérisé en ce que
    le disque membrane (7) est maintenu appuyé par un bord (8) bordé par déformation à chaud du col intérieur (4) du bouchon de fermeture (3).
EP07702363A 2006-02-07 2007-01-18 Procédé de fabrication d'un récipient d'échantillonnage servant à contenir de petites quantités de liquide pour analyses Active EP1981637B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL07702363T PL1981637T3 (pl) 2006-02-07 2007-01-18 Sposób wytwarzania naczynia do pobierania próbek do pobierania małych ilości płynu do analizy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE202006001995U DE202006001995U1 (de) 2006-02-07 2006-02-07 Probengefäß zur Aufnahme von kleinen Flüssigkeitsmengen für Analysen
PCT/DE2007/000082 WO2007090362A1 (fr) 2006-02-07 2007-01-18 Récipient d'échantillonnage servant à contenir de petites quantités de liquide pour analyses

Publications (2)

Publication Number Publication Date
EP1981637A1 EP1981637A1 (fr) 2008-10-22
EP1981637B1 true EP1981637B1 (fr) 2012-04-25

Family

ID=36599848

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07702363A Active EP1981637B1 (fr) 2006-02-07 2007-01-18 Procédé de fabrication d'un récipient d'échantillonnage servant à contenir de petites quantités de liquide pour analyses

Country Status (14)

Country Link
US (1) US20070183937A1 (fr)
EP (1) EP1981637B1 (fr)
JP (1) JP5015964B2 (fr)
CN (1) CN101378837B (fr)
AT (1) ATE554858T1 (fr)
AU (1) AU2007214142B2 (fr)
BR (1) BRPI0707525B1 (fr)
CA (1) CA2641777C (fr)
DE (1) DE202006001995U1 (fr)
DK (1) DK1981637T3 (fr)
ES (1) ES2386821T3 (fr)
PL (1) PL1981637T3 (fr)
RU (1) RU2384369C1 (fr)
WO (1) WO2007090362A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007024539A1 (de) * 2007-05-24 2008-11-27 Fresenius Kabi Deutschland Gmbh Verschlusskappe für ein Behältnis zur Aufnahme von Flüssigkeiten, insbesondere einer enteralen Nährlösung und Behältnis mit einer derartigen Verschlusskappe
GB0722385D0 (en) * 2007-11-14 2007-12-27 Novathera Ltd Vessel cap
DE102008060995A1 (de) * 2008-12-09 2010-06-10 West Pharmaceutical Services Deutschland Gmbh & Co. Kg Verschluss für ein Medikamentenbehältnis
IT1393104B1 (it) * 2009-02-25 2012-04-11 Sentinel Ch S P A Provetta perfezionata per la raccolta, il trasporto e l'estrazione di campioni di feci
US8550273B2 (en) 2010-08-31 2013-10-08 Wheaton Industries, Inc. Cryogenic vials
JP2015500003A (ja) * 2011-11-16 2015-01-05 エピスタム リミテッド 反応容器及び試料マトリクスを含むアセンブリ、試料マトリクス上方吸着性層及び下方横流れ層を含む試料マトリクス
CN103071549A (zh) * 2012-06-15 2013-05-01 郑州安图绿科生物工程有限公司 试剂瓶
DE102012110111A1 (de) 2012-10-23 2014-04-24 Rpc Formatec Gmbh Gefäß
AU2013202805B2 (en) 2013-03-14 2015-07-16 Gen-Probe Incorporated System and method for extending the capabilities of a diagnostic analyzer
MX2016004605A (es) * 2013-10-24 2016-11-14 Astrazeneca Ab Formulaciones de anticuerpos estables acuosas.
WO2017112596A1 (fr) * 2015-12-23 2017-06-29 Chico Technologies Llc Impression dans le moule de tubes
WO2017161058A1 (fr) * 2016-03-15 2017-09-21 Abbott Laboratories Systèmes d'enceinte de réaction et procédés et systèmes pour les utiliser
CA3130654A1 (fr) 2020-09-15 2022-03-15 Norgen Biotek Corp. Appareil de collecte d'echantillons et utilisations connexes
CN112619718B (zh) * 2020-11-17 2022-06-14 浙江省海洋水产研究所 一种免开盖离心管
CN113184356A (zh) * 2021-03-16 2021-07-30 李亚峰 一种密封性好的炎症生化检测试剂盒
CN115138413B (zh) * 2022-08-02 2023-09-22 石家庄元鼎医疗器械有限公司 一种便于取样的穿刺型尿管

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH361086A (de) * 1957-09-20 1962-03-31 Astra Apotekarnes Kem Fab Verschlusspfropfen an Behälter für Injektionsflüssigkeit
DE1935952U (de) * 1966-02-08 1966-03-31 J A Schmalbach Aktiengesellsch Verschluss fuer Kunststoffpackungen
SE388178B (sv) * 1974-09-06 1976-09-27 Pharmacia Ab Tetande forslutning for behallare
US4254884A (en) * 1978-10-20 1981-03-10 Toppan Printing Co., Ltd. Plug body for a container
US4312349A (en) * 1979-07-23 1982-01-26 Cohen Milton J Filter device for injectable fluid
DE3049503C2 (de) 1980-12-30 1983-04-28 Walter Sarstedt Kunststoff-Spritzgußwerk, 5223 Nümbrecht "Blutentnahmevorrichtung"
JPH02212768A (ja) * 1989-02-13 1990-08-23 Terumo Corp 採液管
AT401341B (de) 1990-03-09 1996-08-26 Greiner & Soehne C A Verschlussvorrichtung für ein, insbesondere evakuierbares gehäuse
US5016771A (en) * 1990-09-04 1991-05-21 J. G. Finneran Associates Cap closure and liner
DE4112209A1 (de) * 1991-04-13 1992-10-15 Behringwerke Ag Behaelterverschluss mit durchstossbarem verschlusskoerper
JPH0775663A (ja) 1993-06-25 1995-03-20 Nissho Corp 医療用容器の栓体
US5361921A (en) * 1993-06-29 1994-11-08 Becton Dickinson And Company Combination stopper-shield closure
DE19739369C2 (de) * 1997-09-09 2000-04-06 Sarstedt Ag & Co Blutentnahmevorrichtung
US6568439B1 (en) * 1999-04-20 2003-05-27 Jms Co., Ltd. Container cap and liquid communication adapter
EP1066881A3 (fr) * 1999-07-09 2002-07-03 Becton Dickinson and Company Dispositif de prélèvement d'échantillons avec capuchon
US6426049B1 (en) * 1999-07-09 2002-07-30 Becton, Dickinson And Company Collection assembly
EP1990092B1 (fr) 2001-03-09 2010-02-10 Gen-Probe Incorporated Capot pénétrable
JP3727554B2 (ja) * 2001-06-14 2005-12-14 昭和電工株式会社 輸液容器用口栓体
CN2494699Y (zh) * 2001-09-12 2002-06-12 江苏电分析仪器厂 防腐玻璃密封管
DE10340538B4 (de) 2003-09-03 2005-07-07 Kabe-Labortechnik Gmbh Probenbehälter zur Aufnahme von Flüssigkeiten für medizinische Analysen

Also Published As

Publication number Publication date
PL1981637T3 (pl) 2012-11-30
JP5015964B2 (ja) 2012-09-05
CN101378837B (zh) 2011-11-23
ATE554858T1 (de) 2012-05-15
RU2384369C1 (ru) 2010-03-20
ES2386821T3 (es) 2012-08-31
BRPI0707525B1 (pt) 2018-01-16
JP2009526210A (ja) 2009-07-16
EP1981637A1 (fr) 2008-10-22
WO2007090362A1 (fr) 2007-08-16
US20070183937A1 (en) 2007-08-09
AU2007214142A1 (en) 2007-08-16
CA2641777C (fr) 2014-03-25
CA2641777A1 (fr) 2007-08-16
DE202006001995U1 (de) 2006-06-08
BRPI0707525A2 (pt) 2011-05-03
CN101378837A (zh) 2009-03-04
AU2007214142B2 (en) 2013-01-17
DK1981637T3 (da) 2012-07-30

Similar Documents

Publication Publication Date Title
EP1981637B1 (fr) Procédé de fabrication d'un récipient d'échantillonnage servant à contenir de petites quantités de liquide pour analyses
EP0150172B1 (fr) Tube de prélèvement sanguin
DE60031526T2 (de) Durchdringbare kappe mit innerer spitze
EP0504697B1 (fr) Fermeture pour récipients à réactifs
EP1819275B1 (fr) Tube de prelevement destine a contenir des liquides corporels, en particulier du sang
DE60300304T2 (de) Auszugsröhre zum Sammeln von Stuhlproben
EP1934574B1 (fr) Systeme de prelevement d'echantillons pour des echantillons fluides
DE2824588A1 (de) Einweg-stopfen fuer vakuumroehrchen
DE69218714T2 (de) Verfahren und Anlage für die mikrobiologische Untersuchung von Flüssigkeiten
EP0189391A2 (fr) Tube pour échantillon de sang
DE3112877A1 (de) Wegwerfbare tupf- und kultureinheit
WO2012080310A1 (fr) Dispositif permettant de prélever du liquide contenu dans un récipient
EP1791513A1 (fr) Dispositif pour raccorder un element tubulaire a la zone interieure d'un flacon
DE102011100937A1 (de) Vorrichtung zum Reduzieren des Verdampfens in einer Reagenzflasche
EP1239963A2 (fr) Dispositif de fermeture pour un collecteur d'echantillons sous vide
DE3883730T2 (de) Vorrichtung zum einmaligen Gebrauch zur Entnahme und Aufbewahrung von Blutproben.
EP2153717A1 (fr) Dispositif de caractérisation et de prélèvement d'échantillon pour animaux
DE10340538B4 (de) Probenbehälter zur Aufnahme von Flüssigkeiten für medizinische Analysen
DE10015788A1 (de) Vorrichtung zur Untersuchung der Sterilität von Fluiden
DE2328718B2 (de) Blutentnahmevorrichtung
DE4332087A1 (de) Verschluß- und Entnahmeeinrichtung
WO2017198711A1 (fr) Récipient comprenant un espace de réception et procédé de prélèvement d'une substance présente dans l'espace de réception d'un récipient
DE102009033908A1 (de) Für die Entnahme von medizinischen Flüssigkeiten aus Verpackungen geeignete Vorrichtung und damit ausgestattete Verpackung
DE2147824A1 (de) Verfahren und geraet zur durchfuehrung von blutsenkungen
DE20313316U1 (de) Probenbehälter zur Aufnahme von Flüssigkeiten für medizinische Analysen

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20080828

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

17Q First examination report despatched

Effective date: 20090324

RTI1 Title (correction)

Free format text: METHOD FOR PRODUCING A SAMPLE VESSEL FOR ACCOMMODATING SMALL AMOUNTS OF LIQUID FOR ANALYSES

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 554858

Country of ref document: AT

Kind code of ref document: T

Effective date: 20120515

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: GERMAN

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 502007009771

Country of ref document: DE

Effective date: 20120628

REG Reference to a national code

Ref country code: SE

Ref legal event code: TRGR

REG Reference to a national code

Ref country code: NL

Ref legal event code: T3

REG Reference to a national code

Ref country code: DK

Ref legal event code: T3

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: SCHMAUDER & PARTNER AG PATENT- UND MARKENANWAELTE

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2386821

Country of ref document: ES

Kind code of ref document: T3

Effective date: 20120831

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120425

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120825

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120425

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120425

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120827

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120726

REG Reference to a national code

Ref country code: PL

Ref legal event code: T3

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120425

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120425

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120425

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120425

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20130128

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 502007009771

Country of ref document: DE

Effective date: 20130128

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120725

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20130131

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20130118

REG Reference to a national code

Ref country code: AT

Ref legal event code: MM01

Ref document number: 554858

Country of ref document: AT

Kind code of ref document: T

Effective date: 20130118

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20130118

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20120425

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20070118

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 10

REG Reference to a national code

Ref country code: DE

Ref legal event code: R082

Ref document number: 502007009771

Country of ref document: DE

Representative=s name: GIHSKE GROSSE KLUEPPEL KROSS BUEROGEMEINSCHAFT, DE

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 11

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 12

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230528

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20231221

Year of fee payment: 18

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: SE

Payment date: 20231228

Year of fee payment: 18

Ref country code: NL

Payment date: 20231226

Year of fee payment: 18

Ref country code: FR

Payment date: 20231222

Year of fee payment: 18

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: PL

Payment date: 20231228

Year of fee payment: 18

Ref country code: BE

Payment date: 20231227

Year of fee payment: 18

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: LU

Payment date: 20240112

Year of fee payment: 18

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: LT

Payment date: 20240102

Year of fee payment: 18

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20240205

Year of fee payment: 18

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20240131

Year of fee payment: 18

Ref country code: CH

Payment date: 20240202

Year of fee payment: 18

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: LV

Payment date: 20240103

Year of fee payment: 18

Ref country code: IT

Payment date: 20231228

Year of fee payment: 18

Ref country code: DK

Payment date: 20240111

Year of fee payment: 18