EP1620441A1 - Derives de thiadiazine et leur utilisation comme modulateurs positifs des recepteurs ampa - Google Patents

Derives de thiadiazine et leur utilisation comme modulateurs positifs des recepteurs ampa

Info

Publication number
EP1620441A1
EP1620441A1 EP04742632A EP04742632A EP1620441A1 EP 1620441 A1 EP1620441 A1 EP 1620441A1 EP 04742632 A EP04742632 A EP 04742632A EP 04742632 A EP04742632 A EP 04742632A EP 1620441 A1 EP1620441 A1 EP 1620441A1
Authority
EP
European Patent Office
Prior art keywords
formula
compound
group
compounds
linear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04742632A
Other languages
German (de)
English (en)
French (fr)
Inventor
Emmanuel Graindorge
Pierre Francotte
Stéphane Boverie
Pascal De Tullio
Bernard Pirotte
Pierre Lestage
Laurence Danober
Pierre Renard
Daniel-Henri Caignard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Liege ULG
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Publication of EP1620441A1 publication Critical patent/EP1620441A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
EP04742632A 2003-05-05 2004-05-04 Derives de thiadiazine et leur utilisation comme modulateurs positifs des recepteurs ampa Withdrawn EP1620441A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0305448A FR2854634B1 (fr) 2003-05-05 2003-05-05 Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2004/001070 WO2004099217A1 (fr) 2003-05-05 2004-05-04 Derives de thiadiazine et leur utilisation comme modulateurs positifs des recepteurs ampa

Publications (1)

Publication Number Publication Date
EP1620441A1 true EP1620441A1 (fr) 2006-02-01

Family

ID=33306157

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04742632A Withdrawn EP1620441A1 (fr) 2003-05-05 2004-05-04 Derives de thiadiazine et leur utilisation comme modulateurs positifs des recepteurs ampa

Country Status (21)

Country Link
US (1) US7476668B2 (zh)
EP (1) EP1620441A1 (zh)
JP (1) JP4461139B2 (zh)
KR (1) KR100741235B1 (zh)
CN (1) CN100363368C (zh)
AR (1) AR044245A1 (zh)
AU (1) AU2004236005B2 (zh)
BR (1) BRPI0410002A (zh)
CA (1) CA2524377C (zh)
EA (1) EA009240B1 (zh)
FR (1) FR2854634B1 (zh)
GE (1) GEP20084318B (zh)
HK (1) HK1088327A1 (zh)
MA (1) MA27732A1 (zh)
MX (1) MXPA05011823A (zh)
MY (1) MY136694A (zh)
NO (1) NO20055695L (zh)
NZ (1) NZ543214A (zh)
UA (1) UA80046C2 (zh)
WO (1) WO2004099217A1 (zh)
ZA (1) ZA200508660B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2404605B1 (en) 2004-08-25 2015-04-22 Essentialis, Inc. Pharmaceutical formulations of potassium ATP channel openers and uses thereof
EP2404604B1 (en) 2006-01-05 2019-02-06 Essentialis, Inc. Salts of potassium ATP channel openers and uses thereof
WO2010054336A2 (en) * 2008-11-10 2010-05-14 The Regents Of The University Of California Therapeutic uses of ampa receptor modulators for treatment of motor dysfunction
UY33551A (es) 2010-08-10 2012-03-30 Takeda Pharmaceutical Compuesto heterocíclico y su uso
JP5901365B2 (ja) * 2012-03-12 2016-04-06 株式会社トクヤマ イミダート化合物の製造方法
WO2014201411A1 (en) 2013-06-13 2014-12-18 Veroscience Llc Compositions and methods for treating metabolic disorders
BR112017028639B1 (pt) 2015-07-06 2023-03-21 Public University Corporation Yokohama City University Composto que liga especificamente ao receptor ampa, composição farmacêutica que o compreende, uso do mesmo e métodos para a produção do referido composto e para a formação de imagem de um receptor ampa
JP6241974B1 (ja) 2017-01-11 2017-12-06 公立大学法人横浜市立大学 霊長類生体の脳内ａｍｐａ受容体のイメージング方法、プログラム、及びスクリーニング方法
US10680583B1 (en) * 2019-02-26 2020-06-09 Xilinx, Inc. Control circuit for and method of controlling an operation of an integrated circuit device

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3733409A (en) * 1969-05-20 1973-05-15 Schering Corp Method of treating hypertension using thieno (1,2,4) thiadiazines
WO1998012185A1 (en) * 1996-09-17 1998-03-26 The Regents Of The University Of California Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor
EP1000066A1 (en) * 1997-07-16 2000-05-17 Novo Nordisk A/S Fused 1,2,4-thiadiazine derivatives, their preparation and use
HUP0101280A3 (en) * 1998-02-18 2003-02-28 Neurosearch As Positive ampa receptor modulator compounds and their use
FR2801587B1 (fr) * 1999-11-30 2002-01-11 Adir Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2004099217A1 *

Also Published As

Publication number Publication date
MY136694A (en) 2008-11-28
KR20060006830A (ko) 2006-01-19
FR2854634B1 (fr) 2005-07-08
JP2006525292A (ja) 2006-11-09
WO2004099217A1 (fr) 2004-11-18
NZ543214A (en) 2009-02-28
CN1798750A (zh) 2006-07-05
US7476668B2 (en) 2009-01-13
UA80046C2 (en) 2007-08-10
CA2524377C (fr) 2010-08-24
NO20055695L (no) 2005-12-01
US20070004709A1 (en) 2007-01-04
ZA200508660B (en) 2007-01-31
AR044245A1 (es) 2005-09-07
AU2004236005A1 (en) 2004-11-18
EA009240B1 (ru) 2007-12-28
MXPA05011823A (es) 2006-05-25
CN100363368C (zh) 2008-01-23
CA2524377A1 (fr) 2004-11-18
BRPI0410002A (pt) 2006-04-25
EA200501696A1 (ru) 2006-06-30
KR100741235B1 (ko) 2007-07-19
AU2004236005B2 (en) 2010-01-21
JP4461139B2 (ja) 2010-05-12
FR2854634A1 (fr) 2004-11-12
MA27732A1 (fr) 2006-01-02
GEP20084318B (en) 2008-03-10
HK1088327A1 (en) 2006-11-03

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AX Request for extension of the european patent

Extension state: AL HR LT LV MK

RIN1 Information on inventor provided before grant (corrected)

Inventor name: CAIGNARD, DANIEL-HENRI

Inventor name: RENARD, PIERRE

Inventor name: DANOBER, LAURENCE

Inventor name: LESTAGE, PIERRE

Inventor name: PIROTTE, BERNARD

Inventor name: DE TULLIO, PASCAL

Inventor name: BOVERIE, STEPHANE

Inventor name: FRANCOTTE, PIERRE

Inventor name: GRAINDORGE, EMMANUEL

17Q First examination report despatched

Effective date: 20081210

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: L'UNIVERSITE DE LIEGE

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Effective date: 20130618