EP1602324B1 - Ophthalmic image taking apparatus and ophthalmic image taking method - Google Patents

Ophthalmic image taking apparatus and ophthalmic image taking method Download PDF

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Publication number
EP1602324B1
EP1602324B1 EP05011942A EP05011942A EP1602324B1 EP 1602324 B1 EP1602324 B1 EP 1602324B1 EP 05011942 A EP05011942 A EP 05011942A EP 05011942 A EP05011942 A EP 05011942A EP 1602324 B1 EP1602324 B1 EP 1602324B1
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EP
European Patent Office
Prior art keywords
image
fundus
image taking
imaging magnifications
imaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
EP05011942A
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German (de)
English (en)
French (fr)
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EP1602324A1 (en
Inventor
Kazuhiro Matsumoto
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Canon Inc
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Canon Inc
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Publication of EP1602324A1 publication Critical patent/EP1602324A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes

Definitions

  • the present invention relates to an ophthalmic image taking apparatus having an image taking optical system for imaging an image on an image sensing element at different imaging magnifications and an ophthalmic image taking method.
  • a nondissipative pupil fundus camera for recording data in various image taking media has been known so far.
  • the nondissipative pupil fundus camera observes and aligns a person to be examined under a natural dissipative pupil state by infrared light to record the static image of a color fundus image by visible flash generated by a stroboscope light source. Therefore, when image taking light dazzles, the pupil of the person to be examined contracts. Therefore, when continuing image taking, it is necessary to wait for approx. 10 min until the pupil becomes the natural dissipative pupil.
  • a raw image (raw data) which is not worked is requested and an compressed image may not be recognized as a diagnostic image.
  • the shape of the image becomes a specific shape such as a circle or ellipsoid and it cannot be correctly reproduced by general viewer software.
  • the image is imaged in a small shape, it is necessary to enlarge and display the image when displaying it on a monitor in order to remove an increased margin.
  • one aspect of the present invention is an ophthalmic image taking apparatus comprising:
  • Fig. 1 is a block diagram of a fundus camera.
  • a condenser lens 3, a visible-light cut filter 4 for cutting off visible light but passing infrared light, a stroboscope light source 5 for emitting flash, a diaphragm 6 having an annular opening, an infrared cut filter 7 set so as to be freely inserted or removed to cut off infrared light, a relay lens 8 and a perforated mirror 9 are arranged in a range between an observation light source 1 such as a halogen lamp for emitting visible light and fixed light of infrared light and an objective lens 2.
  • An image-taking diaphragm 10, a focus lens 11 movable on an optical axis, an image taking lens 12, a flip-up mirror 13, a diaphragm 14, a field lens 15, relay lenses 16a and 16b to be alternately inserted into a light path and a digital camera 17 having an image sensing element 17a are arranged and fungus image taking means is constituted at the rear of the objective lens 2.
  • a visual field diaphragm 18, a field lens 19, a mirror 20, an image sensing lens 21 and image sensing means 22 having an image sensing element 22a are arranged in the reflective direction of the flip-up mirror 13, an output of the image taking means 22 is connected to a monitor 23 and fundus observation means is constituted.
  • the output of digital image data by the digital camera 17 is connected to an image control circuit 31.
  • the image control circuit 31 is constituted of an A/D converter 32a, an image board 32 having an image memory 32b serving as memory means for storing digital image data, image control means 33 and a video RAM 34.
  • Image recording means 35 is connected to the image control means 33 and control means 36 and a monitor 37 are connected to the video RAM 34.
  • the recording means 35 uses a drive for writing or reading data in or from a recording medium D capable of holding a memory even if power is not supplied from the outside such as Mo, MD, DVD, card memory or hard disk.
  • An image-taking-mode selection switch 39 having an image taking switch 38 and switches 39S and 39D and a stroboscope control circuit 40 are connected to the control means 36.
  • Light emission of the stroboscope light source 5 is controlled by the stroboscope control circuit 40 and the light intensity to be emitted is controlled by a voltage applied to the condenser 40a of the stroboscope control circuit 40.
  • an image taking person makes a person to be examined seat at the front of a fundus camera and registers an eye to be examined E and the fundus camera while observing the fundus Er of the eye to be examined E with infrared light.
  • the infrared cut filter 7 shunts to the outside of an optical path, the light emitted from the observation light source 1 is condensed by the condenser lens 3, only infrared light is transmitted by the visible-light cut filter 4 and passes through the stroboscope light source 5, the annular opening of the diaphragm 6, the lens 8 and the perforated mirror and is reflected to the left by a mirror portion around the perforated mirror 9 to illuminate the fundus Er through the objective lens 2 and the pupil Ep of the eye to be examined E.
  • the image of the fundus Er illuminated by infrared light passes through the objective lens 2, image taking diaphragm 10, focus lens 11 and image taking lens 12 again and is reflected upward by the flip-up mirror 13, once imaged nearby the visual field diaphragm 18, furthermore condensed by the field lens 19, reflected to the left by the mirror 20 and imaged on the image sensing element 22a of the image sensing means 22 through the image pickup lens 21.
  • the fundus image obtained by the image sensing means 22 is converted into a video signal and displayed on the monitor 23.
  • An image taking person performs register with the eye to be examined E by using not-illustrated operation means while viewing a fundus image 23a displayed on the monitor 23, performs focus adjustment by moving the focus lens 11 and confirms an image taking range.
  • the image taking person observes the fundus image 23a displayed on the monitor 23 and confirms that the image taking range, position and focus adjustment are almost preferable and then operates the switch 39S of the image-taking-mode selection switch 39 in order to perform screening image taking.
  • the control means 36 detecting an input to the switch 39S inserts the relay lens 16a for performing contractive imaging for the relay lens 16b into the optical path, applies a voltage lower than a case of performing image taking by using the relay lens 16b to the condenser 40a of the stroboscope control circuit 40 and charges a little electric charges.
  • a fundus image having the same brightness is obtained at a light intensity to be emitted of 1/m 2 when imaging is performed at a magnification of 1/m times compared to a case of using the relay lens 16b.
  • the image taking switch 38 is operated to image-take fundus.
  • the control means 36 detecting an input to the image taking switch 38 first inserts the infrared cut filter 7 for cutting off infrared light into the optical path, starts light accumulation of the digital camera 17 and transmits a light emission signal to the stroboscope control circuit 40.
  • the stroboscope circuit 40 receiving the light emission signal transmits a trigger signal to the stroboscope light source 5 and discharges electric charges accumulated in the condenser 40a to emit light.
  • the light flux emitted from the stroboscope light source 5 passes through the annular opening of the diaphragm 6, infrared light is removed by the infrared cut filter 7, remaining visible light passes through the relay lens 8 and is reflected to the left by a mirror portion around the perforated mirror 9 to illuminate the fundus Er through the objective lens 2 and pupil Ep.
  • the fundus image thus illuminated passes through the objective lens 2, image taking diaphragm 10, focus lens 11 and image taking lens 12 again, passes through the downside of the flipped-up mirror 13 and is once imaged nearby the visual field diaphragm 14, condensed by the field lens 15 and imaged on the image taking element 17a of the digital camera 17 through the relay lens 16a.
  • the digital camera 17 converts the image information on the whole region of the image sensing element 17a into digital image data and outputs the data to the image control circuit 31.
  • the image control means 33 of the image control circuit 31 cuts out an image in a previously computed range in accordance with a method to be described later and stores the image in the memory 32b.
  • the image data is stored in the recording medium D by the recording means 35 and at the same time, reproduced to the monitor 37.
  • Fig. 2 shows a method for computing the cutout region of an image.
  • the image sensing element 17a of the digital camera 17 is a square pixel of 6,000,000 pixels of length 2,000 x width 3,000 and the size of the effective portion is set to length 20mm x width 30mm.
  • the fundus image 17b is image-picked up at a size smaller than the effective image pickup region (20 x 30) of the image sensing element 17a as shown in Fig. 2 .
  • the image taking range of the eye to be examined E is equal to the range observed by an image taking person through the monitor 23.
  • the image control means 33 cuts out a rectangular region 17c including the image pickup range. Though the calculation method of the cutout region 17c is performed as described below, it is not necessary that the region 17c is rectangular.
  • the image control means 33 records the cut-out region in the recording means 35 and moreover, transfers the image to the outside through communication means according to necessity. Because the image is cut out like a rectangle, it is also possible to view an image-taken image by using an external PC (personal computer) and thereby general-purpose pure software.
  • PC personal computer
  • the switch 39D for selecting the detailed diagnostic mode of the image-taking-mode selection switch 39 is operated.
  • the control means 36 detecting an input to the switch 39D of the image-taking-mode selection switch 39 moves the relay lens 16a to the outside of the optical path, inserts the relay lens 16b, controls the stroboscope control circuit 40 and sets the charge voltage of the condenser 40a to a high value so as to be able to illuminate the eye to be examined E with a light intensity higher than the case of the observing mode.
  • the fundus Er is image-taken by operating the image taking switch 38.
  • the control means 36 detecting an input to the image taking switch 38 first inserts the infrared cut filter 7 into the optical path, starts light accumulation of the image sensing element 17a of the digital camera 17 and transmits a light emission signal to the stroboscope control circuit 40.
  • the stroboscope control circuit 40 receiving the light emission signal transmits a trigger signal to the stroboscope light source 5, discharges electric charges accumulated in the condenser 40a and emits light.
  • the light flux emitted from the stroboscope light source 5 passes through the annular opening of the diaphragm 6 similarly to the observation light, infrared light is removed by the infrared cut filter 7 and remaining visible light passes through the relay lens 8 and is reflected to the left by the peripheral mirror portion of the perforated mirror 9 to illuminate the fundus Er through the pupil Ep of the eye-to-be-examined E through the objective lens 2.
  • the fundus reflective image thus illuminated passes through the objective lens 2, image taking diaphragm 10, focus lens 11 and image taking lens 12 and passes through downside of the flipped-up mirror 13 and is once imaged nearby the visual field diaphragm 14, condensed by the field lens 15, imaged on the image sensing element 17a of the digital camera 17 by the relay lens 16b and converted into digital image data.
  • the image control means 33 stores the digital image data for a fundus image in the memory 32b.
  • the image data is stored in the recording medium D by the recording means 35 and reproduced in the monitor 37.
  • the image is displayed at a size larger than that in the screening mode.
  • the fundus image 17b is largely imaged on the image sensing element 17a as shown in Fig. 3 .
  • the image taking range of the eye to be examined E is equal to the range observed by an image taking person with the monitor 23.
  • the image control means 33 records the whole image data in the recording means 35 without cutting out a specific region from the image data and transfers an image to the outside through communication means according to necessity.
  • the embodiment 1 two modes such as the diagnostic mode and screening mode are set and illumination light intensity, image taking magnification and cutout of an image are set.
  • the operability is further improved as shown by the embodiment 2 in Fig. 4 .
  • release lenses 16a and 16b in Fig. 1 are replaced with a zoom lens 16c and magnifications of the zoom lens 16c can be changed by lens position control means 41 connected to the control means 36.
  • a mode selection switch 42 is used instead of the image-taking-mode selection switch 39 and switches 42H and 42L capable of selecting a degree of an illumination light intensity are set so that the intensity of a selected illumination light intensity and an image size are displayed on display portions 42a and 42b.
  • the control means 36 controls a charging voltage of the condenser 40a of the stroboscope control circuit 40 so as to output selected light-emission energy. Moreover, when controlling the lens position control means 41, each lens of the zoom lens 16c moves and the imaging magnification of an image on an image pickup face is continuously changed by following the above mentioned.
  • the image control means 33 computes the imaging magnification, that is, a cutout region corresponding to the size of the image. Moreover, the control means 36 records the image in the cutout memory 32b in accordance with the computing result.
  • addresses of cutout regions P1, P2, P3 and P4 can be formed into a function as follows by assuming the diameter of the image size of a fundus image as d (mm).
  • the size of the cutout region becomes length d+0.4 mm and width (d+0.4) x 3/2 mm.
  • the size of the pixel to be cut out becomes length (d+0.4)/0.01 pixel and width (d+0.4) x 3/2/0.01 pixel and the center address becomes (1,000, 1,500).

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Eye Examination Apparatus (AREA)
EP05011942A 2004-06-04 2005-06-02 Ophthalmic image taking apparatus and ophthalmic image taking method Expired - Fee Related EP1602324B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004166672A JP2005342283A (ja) 2004-06-04 2004-06-04 眼科撮影装置
JP2004166672 2004-06-04

Publications (2)

Publication Number Publication Date
EP1602324A1 EP1602324A1 (en) 2005-12-07
EP1602324B1 true EP1602324B1 (en) 2009-04-08

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EP05011942A Expired - Fee Related EP1602324B1 (en) 2004-06-04 2005-06-02 Ophthalmic image taking apparatus and ophthalmic image taking method

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US (1) US7354154B2 (ko)
EP (1) EP1602324B1 (ko)
JP (1) JP2005342283A (ko)
KR (1) KR100637288B1 (ko)
CN (1) CN100387184C (ko)
DE (1) DE602005013718D1 (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4901201B2 (ja) * 2005-12-08 2012-03-21 興和株式会社 眼底画像処理方法及び装置
JP2008295971A (ja) 2007-06-04 2008-12-11 Nidek Co Ltd 眼底カメラ
CN101566727B (zh) * 2008-04-22 2010-12-22 深圳市莫廷影像技术有限公司 眼科探头成像系统
CN102370456A (zh) * 2010-08-09 2012-03-14 明达医学科技股份有限公司 眼底光学影像装置
CN102370455A (zh) * 2010-08-09 2012-03-14 明达医学科技股份有限公司 眼底光学影像装置
US8398238B1 (en) * 2011-08-26 2013-03-19 Alcon Lensx, Inc. Imaging-based guidance system for ophthalmic docking using a location-orientation analysis
CN102657515B (zh) * 2012-05-10 2014-03-12 中国科学院长春光学精密机械与物理研究所 应用于视网膜成像系统的对准光路装置
CN102657514B (zh) * 2012-05-10 2014-06-18 中国科学院长春光学精密机械与物理研究所 便携式视网膜成像仪
JP6270312B2 (ja) 2012-11-09 2018-01-31 キヤノン株式会社 眼科装置、画像処理方法およびプログラム
CN103499868B (zh) * 2013-10-10 2016-05-18 山东神戎电子股份有限公司 激光夜视仪同步变焦校正方法
KR20210009196A (ko) 2019-07-16 2021-01-26 주식회사 유엠아이옵틱스 안과용 영상 촬영 장치

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JPS5823098B2 (ja) * 1977-06-30 1983-05-13 キヤノン株式会社 変倍に従つて光量を補正する眼科装置
US4265518A (en) * 1977-06-30 1981-05-05 Canon Kabushiki Kaisha Variable magnification apparatus having illumination compensating ability
JPS5586439A (en) * 1978-12-22 1980-06-30 Canon Kk Ophthalmic inspecting device
JP3073510B2 (ja) 1990-07-27 2000-08-07 株式会社トプコン 眼科撮影装置
JPH05192299A (ja) * 1992-01-21 1993-08-03 Topcon Corp 眼底カメラ
JP3400024B2 (ja) * 1992-08-04 2003-04-28 株式会社トプコン 眼科画像処理システム
DE4326716B4 (de) * 1992-08-04 2005-03-03 Kabushiki Kaisha Topcon Anordnung zur Verarbeitung eines ophthalmologischen Bildes
JPH0788088A (ja) * 1993-09-27 1995-04-04 Topcon Corp 眼科撮影装置
JP3805612B2 (ja) * 2000-10-20 2006-08-02 株式会社ニデック 眼底カメラ
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JP3584246B2 (ja) 2002-06-17 2004-11-04 キヤノン株式会社 眼科撮像装置

Also Published As

Publication number Publication date
KR100637288B1 (ko) 2006-10-24
US7354154B2 (en) 2008-04-08
JP2005342283A (ja) 2005-12-15
CN1706341A (zh) 2005-12-14
DE602005013718D1 (de) 2009-05-20
EP1602324A1 (en) 2005-12-07
KR20060048202A (ko) 2006-05-18
CN100387184C (zh) 2008-05-14
US20050270485A1 (en) 2005-12-08

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