EP1511731A1 - Procede de production d'amides 4-haloalkylnicotiniques - Google Patents

Procede de production d'amides 4-haloalkylnicotiniques

Info

Publication number
EP1511731A1
EP1511731A1 EP03755096A EP03755096A EP1511731A1 EP 1511731 A1 EP1511731 A1 EP 1511731A1 EP 03755096 A EP03755096 A EP 03755096A EP 03755096 A EP03755096 A EP 03755096A EP 1511731 A1 EP1511731 A1 EP 1511731A1
Authority
EP
European Patent Office
Prior art keywords
haloalkyl
formula
acid
iii
nicotinic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03755096A
Other languages
German (de)
English (en)
Inventor
Sergiy Pazenok
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer CropScience AG
Original Assignee
Bayer CropScience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer CropScience AG filed Critical Bayer CropScience AG
Publication of EP1511731A1 publication Critical patent/EP1511731A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Definitions

  • reaction conditions also vary in a manner familiar to the person skilled in the art, depending on whether a compound of the formula (II), (III) or (IV) is used.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procédé de production d'amides 4-haloalkylnicotiniques de formule (I) dans laquelle R<1> représente haloalkyle (C1-C4), qui consiste à soumettre un ou plusieurs 3-(haloalkyl(C1-C4)-3-oxo-1-alcénylamino)nitriles de formule R<1>-C(O)-CH=CH-NH-CH=CH-CN (II), R<1>-C(O)-CH=CH-NH-CH(ZR<2>)-CH2-CN (III) et /ou R<1>-C(O)-CH=CH-NH-CH(Hal)-CH2-CN (IV) dans lesquelles R<1> possède la signification susmentionnée, R<2> représente alkyle (C1-C6), de manière identique ou différente, et Z représente O, S ou NR<1>, de manière identique ou différente, en présence d'un acide fort, à une réaction de cyclisation et à une hydrolyse simultanée. Les composés de formule (I) sont utiles en tant que produits intermédiaires pour la fabrication de produits de lutte contre les parasites.
EP03755096A 2002-05-24 2003-05-09 Procede de production d'amides 4-haloalkylnicotiniques Withdrawn EP1511731A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10223274 2002-05-24
DE10223274A DE10223274A1 (de) 2002-05-24 2002-05-24 Verfahren zur Herstellung von 4-Haloalkylnicotinsäureamiden
PCT/EP2003/004869 WO2003099791A1 (fr) 2002-05-24 2003-05-09 Procédé de production d'amides 4-haloalkylnicotiniques

Publications (1)

Publication Number Publication Date
EP1511731A1 true EP1511731A1 (fr) 2005-03-09

Family

ID=29414153

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03755096A Withdrawn EP1511731A1 (fr) 2002-05-24 2003-05-09 Procede de production d'amides 4-haloalkylnicotiniques

Country Status (13)

Country Link
US (1) US7317105B2 (fr)
EP (1) EP1511731A1 (fr)
JP (1) JP2005535595A (fr)
KR (1) KR20050004218A (fr)
CN (1) CN1310888C (fr)
AU (1) AU2003242532A1 (fr)
BR (1) BR0311246A (fr)
DE (1) DE10223274A1 (fr)
IL (1) IL165356A0 (fr)
MX (1) MXPA04011622A (fr)
TW (1) TW200306977A (fr)
WO (1) WO2003099791A1 (fr)
ZA (1) ZA200408769B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113816901B (zh) * 2021-08-27 2023-08-15 淮北龙溪生物科技有限公司 一种4－三氟甲基烟酰胺的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2994182B2 (ja) 1992-07-23 1999-12-27 石原産業株式会社 アミド系化合物又はその塩、それらの製造方法及びそれらを含有する有害動物防除剤
DE69623532T2 (de) * 1995-05-26 2003-03-20 Ishihara Sangyo Kaisha Verfahren zur Herstellung von 4-Trifluormethylnicotinsäure
DE19725450A1 (de) 1997-06-16 1998-12-17 Hoechst Schering Agrevo Gmbh 4-Haloalkyl-3-heterocyclylpyridine und 4-Haloalkyl-5-heterocyclylpyrimidine, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel
WO2001070692A2 (fr) 2000-03-22 2001-09-27 Bayer Cropscience Gmbh Acylsulfimides heterocycliques, leur procede de preparation, substances les contenant, et leur utilisation en tant qu'agent de lutte contre les parasites
TWI222442B (en) 2000-12-13 2004-10-21 Aventis Cropscience Gmbh Process for the preparation of 4-haloalkylnicotinonitriles
ATE443062T1 (de) 2001-11-21 2009-10-15 Mitsui Chemicals Agro Inc N-heteroarylnikotinamidderivate

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO03099791A1 *

Also Published As

Publication number Publication date
CN1656074A (zh) 2005-08-17
AU2003242532A1 (en) 2003-12-12
MXPA04011622A (es) 2005-03-07
WO2003099791A1 (fr) 2003-12-04
DE10223274A1 (de) 2003-12-04
IL165356A0 (en) 2006-01-15
US20050176734A1 (en) 2005-08-11
CN1310888C (zh) 2007-04-18
US20060100217A9 (en) 2006-05-11
BR0311246A (pt) 2005-03-15
ZA200408769B (en) 2005-12-28
KR20050004218A (ko) 2005-01-12
TW200306977A (en) 2003-12-01
JP2005535595A (ja) 2005-11-24
US7317105B2 (en) 2008-01-08

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