EP1175195B1 - Cuillere a mesurer pour doser des micropastilles - Google Patents

Cuillere a mesurer pour doser des micropastilles Download PDF

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Publication number
EP1175195B1
EP1175195B1 EP00929481A EP00929481A EP1175195B1 EP 1175195 B1 EP1175195 B1 EP 1175195B1 EP 00929481 A EP00929481 A EP 00929481A EP 00929481 A EP00929481 A EP 00929481A EP 1175195 B1 EP1175195 B1 EP 1175195B1
Authority
EP
European Patent Office
Prior art keywords
micro
tablets
dosing spoon
border
dosing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP00929481A
Other languages
German (de)
English (en)
Other versions
EP1175195A1 (fr
Inventor
Thomas Moest
Ludwig Matz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nordmark Arzneimittel GmbH and Co KG
Original Assignee
Nordmark Arzneimittel GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordmark Arzneimittel GmbH and Co KG filed Critical Nordmark Arzneimittel GmbH and Co KG
Publication of EP1175195A1 publication Critical patent/EP1175195A1/fr
Application granted granted Critical
Publication of EP1175195B1 publication Critical patent/EP1175195B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015—Devices specially adapted for taking medicines
    • A61J7/0023—Spoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015—Devices specially adapted for taking medicines
    • A61J7/0053—Syringes, pipettes or oral dispensers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/02—Pill counting devices

Definitions

  • the present invention relates to a measuring spoon for microtablets the preamble of claim 1.
  • Multi unit dose (MUD) forms are usually dosed by capsules.
  • MUD formulations the effective ingredient is on divided many individual sub-dosage forms, such as pellets or micro-tablets.
  • a formulation of the dosage form as a pile, i.e. H. as a filling in one Container, and the dose-appropriate removal with z. B. a spoon or Measuring spoon is particularly useful for smaller volumes, such as. B to whom the usual capsule contents, rather imprecise and only with large ones Variations reproducible.
  • a spoon or Measuring spoon is particularly useful for smaller volumes, such as. B to whom the usual capsule contents, rather imprecise and only with large ones Variations reproducible.
  • With common pellet formulations This is aggravated by the fact that the manufacturing-related irregularity of the grain sizes with a volume withdrawal the fluctuation range is still enlarged and thus the demands of the European Pharmacopoeia according to dosage uniformity, as for tablets executed there, cannot be complied with.
  • Micro-tablets with a diameter range of 1.0 to 3.0 mm can be relatively simple with uniform size and constant drug content getting produced. A very precise individual section of the In principle, the dose could be given by counting the microtablets, however, this cannot be expected of the patient, especially if he has to count large amounts of micro-tablets.
  • NL 66782 C discloses a scoop-like measuring spoon for tablets, in which a lower part with a number of holes for receiving of the tablets is provided on the underside by means of a Lower part connected base plate are closed. On the lower part and a handle is attached to the base plate. The bottom part is on everyone Margin pages except on one side, with the rimless side has a shovel-like opening and the handle is opposite. It is also firmly on the edge of the lower part and attached a transparent cover plate at a distance from it.
  • the transparent cover plate is with a cross to the direction of Handle extending upper dividing strip provided over the cover plate protrudes upwards and has a lower dividing strip, which is arranged on the underside of the cover plate, both Separating strips and the holes in the lower part are installed so that the holes completely between the handle and the dividers are located.
  • the top divider prevents tablets from getting on top of the holes of the lower part.
  • the two ends of the The edge tapers towards the tip, with one at one of these ends transparent guide plate is attached.
  • the measuring spoon is sufficient filled from the crowd with simultaneous shaking movements towards the surface of the lower part with the holes in one after pulled forward inclined position, then each hole with a tablet filled and the excess tablets slide back from the lower part in the crowd.
  • the amount of tablets thus secreted To fill in a package, the measuring spoon is cut by half Rotation rotated so that the parts lie on the cover plate, then the measuring spoon turned back a quarter turn, causing the tablets along the smooth surface of the cover plate into the part slide the edge where the end together with the guide plate form a gutter where along the parts in the packaging, e.g. B. a box, can be inserted.
  • a device has now been found with which one can easily precise dosing by taking an exact number of microtablets can reach from a storage vessel.
  • the invention relates to a measuring spoon for micro-tablets with the Claim 1 characterized features.
  • the measuring spoon consists of the individual wells for Inclusion of the microtablets in the lower part of the open top
  • Dosing spoons consist of cylindrical bores that are offset at an angle arranged rows are formed in the lower part, and that the edge-free side of the lower part parallel to the longitudinal axis of the dipper stick is running, the lengthwise to the side having the edge of the lower part runs opposite the edge-free side of the lower part is.
  • the invention thus relates to a measuring spoon for microtablets which the lower part 1 of the spoon consists of a flat polygon, which has a margin 2 on all sides with the exception of one side, and the polygon has a series of individual depressions 3 which are shaped so that a single microtablet in each well fits.
  • the polygon is usually a square, with the two sides facing the face each other, have the same length (parallelogram).
  • the small Angle 4 of the parallelogram is between 45 ° and 90 °.
  • a long Page 5 of the parallelogram and the two smaller pages 6, 7 are provided with an edge 2, something. H. up to 5 mm, vertically above the polygon protrudes.
  • Small cylindrical bores 3 are embedded in the polygon of the dosing spoon, the diameter and depth of which are dimensioned such that a micro-tablet fits comfortably into each opening.
  • the diameter of the holes is between 1, 5 and 4.0 mm. The same applies to the depth of the holes. In a special case, the diameter and depth should be 0.2 mm larger than the largest diagonal of the micro-tablet for which the measuring spoon is to be used.
  • the cylindrical holes are usually arranged so that as many holes as possible fit on 1 cm 2 of the polygon.
  • the total number of holes corresponds to the amount of microtablets to be taken. This number is usually 5 to 100, preferably 10 to 60.
  • the dipper stick 10 is preferably longer in the extension of the side Edge attached.
  • Fig. 1 is a top view of the measuring spoon from above and Fig. 3 shows the spoon from below.
  • Fig. 2 is a cross section through the spoon in the longitudinal direction and Fig. 4 in the transverse direction.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Table Equipment (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Claims (8)

  1. Cuillère à mesurer pour doser des micropastilles avec un manche de cuillère (10) et avec une partie inférieure (1) qui est constituée par un polygone plat qui est pourvu d'un bord (2) sur tous ses côtés à l'exception d'un côté et la partie inférieure (1) présentant plusieurs rangées de creux individuels qui sont formés de telle manière qu'une micropastille individuelle rentre dans chaque creux individuel, où les creux individuels pour loger les micropastilles sont constitués dans la partie inférieure (1) par des perçages cylindriques (3) qui sont configurés dans des rangées placées décalées en oblique dans la partie inférieure (1), caractérisée en ce que la cuillère à mesurer est configurée ouverte vers le haut et que le côté sans bord (8) de la partie inférieure (1) est parallèle à l'axe longitudinal du manche de cuillère (10) qui est dans le sens longitudinal par rapport au côté de la partie inférieure (1) qui présente le bord, ce côté étant opposé au côté sans bord (8) de la partie inférieure (1).
  2. Cuillère à mesurer selon la revendication 1,
    caractérisée en ce que le polygone de la partie inférieure (1) est constitué par un tétragone en forme de parallélogramme pour lequel les côtés opposés ont les mêmes longueurs, le petit angle (4) entre deux côtés du parallélogramme étant de préférence situé entre 45° et 90° et un long côté (5) du parallélogramme ainsi que les deux côtés courts (6, 7) étant pourvus d'un bord (2).
  3. Cuillère à mesurer selon la revendication 2,
    caractérisée en ce que le bord (2) des deux côtés plus courts (6, 7) du parallélogramme fait légèrement saillie, par exemple jusqu'à 5 mm perpendiculairement au-dessus du polygone.
  4. Cuillère à mesurer selon l'une des revendications 1 à 3,
    caractérisée en ce que le diamètre et la profondeur du perçage cylindrique (3) sont plus grands que la plus grande diagonale d'une micropastille.
  5. Cuillère à mesurer selon l'une des revendications 1 à 4,
    caractérisée en ce que le diamètre et la profondeur du perçage cylindrique (3) sont situés entre 1,5 mm et 4,0 mm.
  6. Cuillère à mesurer selon l'une des revendications 1 à 5,
    caractérisée en ce que le placement des perçages cylindriques (3) dans la partie inférieure (1) est très serré les uns à côté des autres.
  7. Cuillère à mesurer selon l'une des revendications 1 à 6,
    caractérisée en ce que le nombre total des perçages cylindriques (3) dans la partie inférieure (1) correspond à la quantité de micropastilles à loger, le nombre des perçages cylindriques (3) se situant de 5 à 100, de préférence de 10 à 60.
  8. Cuillère à mesurer selon l'une des revendications 1 à 7,
    caractérisée en ce qu'une zone sans perçage, qui est large de préférence d'1 cm au maximum, est configurée sur le côté sans bord (8) du polygone pour un remplissage facilité des perçages cylindriques (3) avec des micropastilles.
EP00929481A 1999-05-06 2000-05-03 Cuillere a mesurer pour doser des micropastilles Expired - Lifetime EP1175195B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE29907996U 1999-05-06
DE29907996U DE29907996U1 (de) 1999-05-06 1999-05-06 Dosierlöffel für Mikrotabletten
PCT/EP2000/003963 WO2000067695A1 (fr) 1999-05-06 2000-05-03 Cuillere a mesurer pour doser des micropastilles

Publications (2)

Publication Number Publication Date
EP1175195A1 EP1175195A1 (fr) 2002-01-30
EP1175195B1 true EP1175195B1 (fr) 2003-08-06

Family

ID=8073160

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00929481A Expired - Lifetime EP1175195B1 (fr) 1999-05-06 2000-05-03 Cuillere a mesurer pour doser des micropastilles

Country Status (7)

Country Link
US (1) US6811054B1 (fr)
EP (1) EP1175195B1 (fr)
JP (1) JP3816751B2 (fr)
AT (1) ATE246481T1 (fr)
DE (2) DE29907996U1 (fr)
DK (1) DK1175195T3 (fr)
WO (1) WO2000067695A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29916187U1 (de) * 1999-09-15 2001-02-08 Schaack Angelika Medizinlöffel
DE10309473A1 (de) * 2003-03-05 2004-09-23 Nordmark Arzneimittel Gmbh & Co. Kg Feste, exakt dosierbare pharmazeutische Darreichungsformen zur Einzelausgabe aus Dosiervorrichtungen
DE102006006532B4 (de) * 2006-02-10 2007-11-08 Biogenerics Pharma Gmbh Pharmazeutische Zubereitung
US20070292566A1 (en) * 2006-06-16 2007-12-20 Degennaro Sergio K Edible spoon for administering liquid medications
DE202009001737U1 (de) 2009-02-10 2009-06-25 Ritter Pharma-Technik Gmbh Dosierspatel
US8683705B2 (en) 2010-09-29 2014-04-01 Ucb Manufacturing, Inc. Dosing spoon
US10604329B2 (en) * 2017-08-18 2020-03-31 Gary Strand Apparatus for medication management
US11446211B2 (en) 2019-02-21 2022-09-20 Merck Sharp & Dohme Llc Variable, multi-dose microtablet dispenser
DE102021000415A1 (de) 2021-01-28 2022-07-28 Gisbert Bohny Dosierhilfen

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL66782C (fr) *
CH242049A (de) * 1945-07-30 1946-04-15 Xaver Muenzel Franz Löffel zum Zählen und Abfüllen von vielen gleichen, kleinstückigen Gegenständen, insbesondere Pillen und Tabletten.
JPS54123179U (fr) * 1978-02-17 1979-08-28
JPS5951813A (ja) * 1982-09-20 1984-03-26 原川　博 スプ−ン
JPS6048767U (ja) * 1983-09-09 1985-04-05 山田　俊男 シヤ−ベツト用スプ−ン
JPS6331670Y2 (fr) * 1985-09-18 1988-08-23
JPH0618549Y2 (ja) * 1989-03-24 1994-05-18 アップリカ葛西株式会社 スプーン
US5785194A (en) * 1991-06-07 1998-07-28 Warner-Lambert Company Cap for a container and opening means therefor
JP3022348U (ja) * 1995-09-02 1996-03-22 豊 宮内 錠剤定数取出し具
JPH1024091A (ja) * 1996-07-10 1998-01-27 Noboru Mori 粒体物等のためのカウンティングスプーン

Also Published As

Publication number Publication date
DE50003192D1 (de) 2003-09-11
DE29907996U1 (de) 1999-07-29
JP3816751B2 (ja) 2006-08-30
JP2002543883A (ja) 2002-12-24
ATE246481T1 (de) 2003-08-15
WO2000067695A1 (fr) 2000-11-16
US6811054B1 (en) 2004-11-02
DK1175195T3 (da) 2003-10-27
EP1175195A1 (fr) 2002-01-30

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