EP0820320A1 - Vorrichtung zum ausgeben von flüssigkeit in abgeteilten mengen - Google Patents

Vorrichtung zum ausgeben von flüssigkeit in abgeteilten mengen

Info

Publication number
EP0820320A1
EP0820320A1 EP97902300A EP97902300A EP0820320A1 EP 0820320 A1 EP0820320 A1 EP 0820320A1 EP 97902300 A EP97902300 A EP 97902300A EP 97902300 A EP97902300 A EP 97902300A EP 0820320 A1 EP0820320 A1 EP 0820320A1
Authority
EP
European Patent Office
Prior art keywords
receptacle
sleeve
particular according
spring
storage space
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97902300A
Other languages
German (de)
English (en)
French (fr)
Inventor
Alfred Von Schuckmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0820320A1 publication Critical patent/EP0820320A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/204Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically connected to external reservoirs for multiple refilling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206With automatic needle insertion

Definitions

  • 00001 Device for dispensing liquid in divided quantities 00003 00004 The invention relates to a device for 00005 dispensing liquid in divided quantities from 00006 a storage room, preferably in the form of a cartridge, via a dispensing mouthpiece, preferably in Ge ⁇ 00008 is a pre-inserted injection needle.
  • 00009 00010 injection devices of this type are known, be it in 00011 in the form of rod-shaped devices (US Pat. No. 2,591,457) or in 00012 in the form of vaccination guns (US Pat. No. 2,472,116).
  • Such 00013 devices have a stroke adjustable spring hammer 00014. It is located in the back of a loading chamber, in 00015 a conventionally designed syringe can be used 00016.
  • the object of the invention is to provide a generic device that divides reproducible quantities coming from a storage space in a simple manner and makes 00025 easy to apply. This object is achieved by the invention specified in claims 00028. 00029 00030 As a result of such a configuration, a generic 00031 device of increased utility value is achieved. This is initially achieved by a buffer store that takes over the partitioned amount from 00033 to the storage space, to which a 00034 discharge piston is assigned, with a passage channel 00035 for filling the buffer store. The one to spend 00036 amount is from the back of the dispensing piston
  • 00052 recording can be moved in the opposite direction
  • the injection stroke can be a injection needle
  • 00070 sleeve continues, which surrounds the recording. Both 00071 parts lead each other and also give each other
  • the device of the invention is practical in the
  • 00076 dimensions of a cigarette box can be designed.
  • 00089 further training feature is that the filling
  • 00090 opening is plugged. It can
  • 00096 direction can only be loaded with a stopper.
  • triggering 00106 set button on an arm of a double-arm release lever is particularly advantageous from the structural point of view that the triggering 00106 set button on an arm of a double-arm release lever
  • FIG. 2 the device in an exploded view, with 00155 changing the cartridge, removed handle, 00156 as well as showing a cannula with separated 00157 cannula protection, 00158 00159
  • Figure 3 shows the device in vertical section, closed 00160 sen and unloaded (representing the situation according to Figure 1 00161), 00162 00163 Figure 4, the device loaded, also in vertical section 00164, 00165 00166
  • Figure 5 shows a vertical section through the removed 00167 handle , 00168 00169 FIG. 6 the device in or after carrying out the 00170 injection and 00171 00172
  • FIG. 7 an enlargement of the check valve 00174 located between the storage space 00173 and the intermediate store.
  • 00176 The device V designed as an injection device
  • 00177 comprises a substantially elongated, rectangular one
  • liquid 2 it can be a medicinal product.
  • the storage room 3 is a replaceable cartridge
  • 00201 is open at the bottom and contains a trailing piston
  • 00208 a crimp cap 16. It consists of metal foil.
  • 00210 source can be exposed in a known manner.
  • the conveyor 00211 cap 16 adheres to the neck-side lower edge of a 00212 bead-widened portion of the neck 13.
  • 00213 00214 The quantity 2 'of liquid 2 originating from the above-mentioned source 2' of liquid 2 is brought to the dispensing mouthpiece 4 via an intermediate storage 17 00217 which limits the corresponding dispensing volume, where it is brought to the destination via injection needle 5.
  • the corresponding flow bridge forms a central passage 00220 channel 18.
  • a discharge piston 19 is assigned to the intermediate store 17. This leads in a cylinder 20.
  • the passage channel 18 extends both over the entire length of a piston skirt 00228 and over the 00229 area of the dispensing piston 19 itself and 00230 even continues in a central pipe socket 22.
  • the 00231 clearly projects beyond the end surface 00232 of the dispensing piston 19 on the intermediate storage side. In the closed, unselected position 00233 as well as in the injection position, the protruding 00234 the pipe socket 22 tapering toward the free end 00235 into a correspondingly pointed 00236 den Cavity section 4 'of the dispensing mouthpiece 4.
  • the divided amount 2''00238 is thus completely displaced from the intermediate store 17, especially since 00239 the end face of the dispensing piston 19 in the transition area of the cylindrical section of the cylinder 20 towards the 00241 area adequate contour, ie the contour 4 1 'corresponding to the 00242 shoulder.
  • 00243 00244 The storage section end portion of the piston skirt 00245 21 and a screw base 23. Its external thread 00246 engages in a suitable internal thread of a cup-shaped 00247 receptacle 24.
  • a bottom-forming transverse wall 26 of the receptacle 24 is centrally perforated 00256.
  • the transverse wall 26 divides the pot cavity 25 00257 into a longer space on the supply side and on the output side - 00258 on the piece side - into a shorter space which accommodates the screw socket 00259.
  • the transverse wall 26 leaves a connection 00260 channel 27.
  • the dome 30 carries a correspondingly curved wall section 00275 31. It forms a check valve 32. It 00276 is a slotted valve. The edge of the domför ⁇ 00277 mig coupled wall section 31 is rooted in a 00278 hat-shaped sealing insert 33 between the stepped 00279 hollow end face of the screw base 23 and the 00280 counter-profile unit projection / dome 29/30. 00281 The joint is dimensioned accordingly.
  • the sealing insert 33 of course consists of rubber or 00283 rubber-elastic material. Screw base on the front of the 00284 wall section is left play.
  • the 00296 slot edge of the wall section 31 can be slightly different from the dome 30, according to 00298 the contour-matched, ie semi-spherical, concave 00299 cavity 23 'of the screw base 23, which acts as a 00300 intermediate chamber.
  • 00301 00302 Tightening of false air via the discharge mouthpiece 4 00303 is avoided by a protective cap 00304 pe 34 which acts as a seal.
  • This contains a sealing body 00306 per 35 which sits on the mouth end of the 00305 relevant channel section (cf. FIG. 3).
  • 00307 00308 The protective cap 34 also acts as a loading handbail 00309 of the device V.
  • the opening 00321 of this cover 40 faces away from the outer housing 1, 00322 while the opening of the protective cap 34 is oriented in the opposite direction 00323.
  • the stop position is 00324 Figure 3.
  • the handle H plunges approximately half the length 00325.
  • 00326 00327 To increase the grip, the free-standing jacket part 00328 is roughened, that is to say the part not immersed in the annular space 41 00329, in particular longitudinally grooved. 00330 The grooves have the reference number 42.
  • the cup-shaped 00331 cover 40 has a central ring socket 43. 00332 The towers over the free end of the cover.
  • 00333 diameter is dimensioned such that the ring wall 10 or 00334 tive the same diameter cylinder 20 are axially 00335 guided therein.
  • the ring connector 43 fits into a 00336 counter-ring space 44 of the 00337 protective cap 34, which is also double-walled.
  • the sealing body 35 received by an inner ring wall 45 is supported on a transverse wall 46 00339 of the same.
  • 00340 00341 The cylinder 20 continues into a 00342 sleeve 47 on the storage space side. The latter surrounds the receptacle 24, which is guided therein in an axially limited manner.
  • the end-side stop is formed by a clipped-in ring plate 48.
  • the spring 50 acts in the longitudinal center
  • 00364 is the sleeve 47 which surrounds and guides it
  • a 00384 with its end turn on the housing position secured in 00385 outer housing 1 from.
  • a 00386 stub 56 also acts in a position-centering manner.
  • the bolt-side end turn is in 00387 in a trough 57.
  • the actual support-active part 00388 is formed by a nose 58. This is under the ring shoulder 49 00390 with its underside forming a blocking shoulder 49 00390 sleeve 47.
  • the support component 54 rests on a 00391 sliding surface 59, formed by the interior of the outer housing 00392 1.
  • 00393 00394 The release of the locking mechanism takes place via a release lever 00395 bel 60.
  • trigger lever 60 extends essentially parallel 00408 extending laterally to the side of the sleeve / receptacle unit 24/47 in the 00409 outer housing 1 of the device V.
  • the other 00410 arm b of the trigger lever 60 extends into the Area of the support component 54. It engages there via a joint 00412 pin 64 on it.
  • a load on the release button 62 in the direction of the arrow P 00413 translates into a movement canceling the locking Rl in 00414, ie the nose 48 00415 is pulled away under the annular shoulder 49, so that the 00416 spring-loaded sleeve 47 and with it the 00417 Snap the receptacle 24 in the loading position.
  • the guide direction lies approximately transversely 00428 to the longitudinal central axis xx of the unit holder / sleeve 00429 24/47.
  • a pin-like portion of the 00430 locking piece 65 which passes through an opening 67 of the wall 00431 extension of the sleeve 47 and with its free 00432 inner end creates the actual abutment W with respect to 00433 the receptacle 24 is located outside the 00434 Lying surface of the sleeve 47 lying, a control bevel 00435 68.
  • the locking piece 65 is in the direction of the locking position 00436 under the load of a spring 69, which is supported 00437 at the end of a guide bracket 66 which creates the guide 66 00438 le. 00439 00440
  • the control bevel 68 is set at an acute angle to the 00441 longitudinal central axis xx so that the nose 58 of the 00442 support component 54 can retract from below with release of the locking Rl 00443.
  • 00444 there is a release of the receptacle 24, which then shifts under 00445 the pressure of the spring 50 relative to the sleeve 47.
  • 00446 The quantity 2 '00447 contained in the intermediate store 17 is injected.
  • the control bevel 68 cooperates with the back of the nose 58 00450, which acts as a correspondingly obliquely oriented 00451 control counter surface 70.
  • 00452 00453 The receptacle 24 continues in a transversely protruding 00454 slide tensioning lever 71. Via the latter, the receptacle 24 can be moved 00455 relative to the sleeve 24 against the force 00456 of the spring 50.
  • the sliding tensioning lever 71 extends through a longitudinal slot 72 in the wall of the sleeve 47. Its usable length corresponds to the displacement stroke 00459 between the receptacle 24 and the sleeve 47 relative to one another.
  • the stopper bears the 00478 reference numeral 76. In its wide, stop-forming end or base area, it is provided with a thread 77 00 480, which with a corresponding counter thread of a threaded hole 00482 78 of the outer housing 1 lying congruent to the filling opening 75 .
  • a 00487 last and third, again separated zone is in 00488 a central cavity of the trailing piston 12, the 00489 is stiffened via a suitably dimensioned bushing 79.
  • the stopper 76 has a length of 00493 that forces the 00492 to dock the cartridge K in an operational manner, but an axial clearance F (FIG.
  • 00494 is taken into account that essentially or at least 00495 the standing length of the hollow needle 28 corresponds.
  • the cartridge 00496 K is consequently only connected to the flow channel 00497 27 and the adjoining passage channel 18 00498 in terms of flow when the device V 00499 is loaded, that is to say the division of the quantity 2 'into the 00500 buffer store 17 takes place.
  • 00501 00502 The function of the device V is as follows: by opening the storage room 3, the cartridge K is assigned 00504 net.
  • the plug 76 can be actuated in terms of thread due to a gripping slot 00505, for example with the aid of a coin 00506.
  • the insertion of the cartridge K is shown in Figure 00507 2.
  • the docking position as shown in FIG. 3, can be carried out right from the start, while overcoming the described axial clearance F 00510 by willpower 00509 by simply inserting the cartridge 00511 fully into the cavity 25 and assigning the stopper 00512.
  • the use of the axial free passage would have the advantage that the flow bridge is not set until 00514 when the device is used, that is to say the injection needle 00515 del 5 is assigned.
  • 00516 00517 To bring about the ready-to-charge position, 00518 is then moved with the aid of the handle H, that is to say the 00519 closure cap 34, which, for example, protrudes from a cylinder 20 protruding from use 00521 against the load 00521 of the spring 51 into the interior of the outer housing 1.
  • the handle H that is to say the 00519 closure cap 34, which, for example, protrudes from a cylinder 20 protruding from use 00521 against the load 00521 of the spring 51 into the interior of the outer housing 1.
  • the Luer connector 6 results in 00523 via the threaded strips 38 the corresponding operational
  • the key press results in the 00570 support member 54 moving away from the sleeve 47 to the 00571 sequence.
  • the sleeve 47 loses its support via the 00572 nose 58 and flips downward in the direction of the arrow 00573 y.
  • the injection needle 5 protrudes from 00574 of the cover 40, which otherwise protects it, 00575, so that it freely passes over the central ring socket 43 00576 and penetrates into the place of movement 83 of a living being 00577.
  • Subcutaneous or intramuscular injection 00578 occurs quickly.
  • the set-up works in such a way 00593 that the delivery plunger 19 together with its receptacle 24 containing the storage space 00594 3 only moves upwards while filling, i.e. exercising a loading stroke in the direction of arrow y of the intermediate store 00596 17 and according to 00597
  • the 00598 cylinder 20 of the discharge piston 19, which forms the intermediate store 17 is released, along with this receptacle 24, it is moved in the opposite direction of the arrow y 00600.
  • This opposite stroke i.e.
  • the shifting movement 00601 in the opposite direction to arrow 00602 y takes place in chronologically successive phases 00603, consisting of a feed stroke that pushes the injection needle 5 out of the cover 40 and a 00605 spray stroke. While the phases initially run synchronously, in the final phase there is the subsequent spray 00607 stroke. 00608 00609 It is particularly advantageous in terms of handling that these 00610 two phases are released via the common trigger button 62 free 00611 with corresponding release of the spring effects 00612. 00613 00614 Reloading is only possible if the injection needle 00615 5 has been removed.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Coating Apparatus (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
EP97902300A 1996-02-12 1997-02-03 Vorrichtung zum ausgeben von flüssigkeit in abgeteilten mengen Withdrawn EP0820320A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19604838A DE19604838A1 (de) 1996-02-12 1996-02-12 Vorrichtung zum Ausgeben von Flüssigkeit in abgeteilten Mengen
DE19604838 1996-02-12
PCT/EP1997/000469 WO1997029797A1 (de) 1996-02-12 1997-02-03 Vorrichtung zum ausgeben von flüssigkeit in abgeteilten mengen

Publications (1)

Publication Number Publication Date
EP0820320A1 true EP0820320A1 (de) 1998-01-28

Family

ID=7785010

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97902300A Withdrawn EP0820320A1 (de) 1996-02-12 1997-02-03 Vorrichtung zum ausgeben von flüssigkeit in abgeteilten mengen

Country Status (11)

Country Link
US (1) US6056728A (no)
EP (1) EP0820320A1 (no)
JP (1) JP2000506025A (no)
KR (1) KR19980703873A (no)
AU (1) AU723084B2 (no)
CA (1) CA2218032A1 (no)
DE (1) DE19604838A1 (no)
NO (1) NO974649D0 (no)
PL (1) PL322846A1 (no)
TR (1) TR199701145T2 (no)
WO (1) WO1997029797A1 (no)

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US6056728A (en) 2000-05-02
KR19980703873A (ko) 1998-12-05
TR199701145T2 (xx) 1998-11-23
AU723084B2 (en) 2000-08-17
PL322846A1 (en) 1998-02-16
AU1599397A (en) 1997-09-02
DE19604838A1 (de) 1997-08-14
JP2000506025A (ja) 2000-05-23
WO1997029797A1 (de) 1997-08-21
MX9707787A (es) 1998-06-28
NO974649L (no) 1997-10-08
NO974649D0 (no) 1997-10-08
CA2218032A1 (en) 1997-08-21

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