EP0601283B1 - Verschluss für eine Medikamentenflasche - Google Patents

Verschluss für eine Medikamentenflasche Download PDF

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Publication number
EP0601283B1
EP0601283B1 EP19930113459 EP93113459A EP0601283B1 EP 0601283 B1 EP0601283 B1 EP 0601283B1 EP 19930113459 EP19930113459 EP 19930113459 EP 93113459 A EP93113459 A EP 93113459A EP 0601283 B1 EP0601283 B1 EP 0601283B1
Authority
EP
European Patent Office
Prior art keywords
tongue
opening
metal foil
closure
crimp cap
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP19930113459
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0601283A1 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pohl GmbH and Co KG
Original Assignee
Pohl GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pohl GmbH and Co KG filed Critical Pohl GmbH and Co KG
Publication of EP0601283A1 publication Critical patent/EP0601283A1/de
Application granted granted Critical
Publication of EP0601283B1 publication Critical patent/EP0601283B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Definitions

  • the invention relates to a closure for a medication bottle, comprising a sealing element which can be placed on the mouth of the medication bottle and is made of polymeric material and is pressed against the mouth by a metallic crimp cap, the crimp cap being provided with an opening in the region of its base and in the edge region on at least one Circumferential point is severable.
  • Such a closure is known from DE-PS 32 41 283.
  • the closure comprises a closure plug made of a deformable, elastic material which can be penetrated by a needle and a ring made of plastic which presses the closure plug onto the mouth of the container under axial pretension.
  • the ring is crimped onto the bottle neck and has a central passage opening which is covered by a pull-out cover.
  • the cover is fastened tightly and tearably on the ring.
  • This configuration is intended on the one hand to ensure a germ-free seal and, on the other hand, that users perceive destruction or removal of the cover immediately. It should be noted, however, that the manufacture of such a closure is unsatisfactory from a manufacturing and economic point of view. A germ-free seal between the cover and the sealing plug is only guaranteed if the closure is manufactured with high precision. Especially the storage of the drug over long periods of time is problematic because the ring shows signs of relaxation over time has and a perfect seal is therefore not guaranteed.
  • the invention has for its object to develop a closure of the type mentioned in such a way that it seals the drug bottle to be sealed over a long period of use and is inexpensive to manufacture in terms of production technology and economy.
  • the closure should also be able to be used with small bottle diameters, the bottle neck of which has a diameter of less than 20 mm.
  • the crimp cap of the closure has a tongue protruding into the opening, with a tongue base which is at least sharply delimited at the circumferential point relative to the crimp cap and with a tongue tip which is inseparably attached to a metal foil which covers the opening in its entirety and is germ-free sealing. wherein the metal foil on the opposite side of the tongue is manually lifted and designed to be removable from the opening in the direction of the tongue.
  • the handling of such a closure is particularly simple.
  • the metal foil is formed, for example, by an aluminum foil which is fastened in the region of the annular bottom on the crimp cap, which can be made of aluminum, for example.
  • the metal foil In order to expose the opening and the sealing element made of flexible, polymeric material underneath, the metal foil is pulled off in the direction of the tongue, so that the contents of the medication bottle are then removed with the help of an injection needle, which holds the sealing element penetrates, can be removed.
  • the metal foil and the crimp cap are inseparably connected in the area of the tongue, which makes it possible to pull the metal foil further in the tear-open direction over the opening to remove the closure from the medication bottle and together with the tongue over the edge region of the base and the flange edge adjoining in the axial direction to separate from the crimp cap.
  • the crimp cap which is then radially severed at a circumferential point can then be removed from the bottle neck without any problems and, like the freely accessible sealing element, can be recycled.
  • the metal foil and the tip of the tongue can be connected by an adhesive zone.
  • the adhesive force of the adhesive and the material thickness of the crimp cap are to be matched to one another in such a way that a separation of the crimp cap is ensured without the bond between the metal foil and the tip of the tongue being released.
  • a hot melt adhesive is preferably used as the adhesive. This can cover the film and / or the material forming the crimp cap in the manner of a film and, for activation in a manner known per se, be temporarily heated to the required extent and solidified by subsequent cooling. The use of a heated pressure die or vibration welding is preferred in the present case.
  • the bonding zone can be provided with an extension that surrounds the opening in a ring-shaped manner in order to ensure a germ-free sealing of the closure on the medication bottle.
  • the bonding zone is in the area of the extension is dimensioned very narrow and is possibly designed only in the manner of a line train.
  • An embodiment in which the adhesive zone in the area surrounding the opening consists of mutually adjacent adhesive points is also possible and in many cases sufficient if the storage and use of the medication bottle is subject to strict control.
  • the microbicidal properties of the metal also result in a barrier effect against penetrating pathogens in the area of an atrium. Under normal hygienic conditions, sufficient sterility of the central area of the opening can often be ensured during a normal storage period, with the tear-open process being considerably easier.
  • the metal foil preferably has a shape adapted to the shape of the crimp cap.
  • the edge region of the base which delimits the opening, can be flanged inwards and in the direction of the outer circumference, the flanging being sharp-edged in the region of the circumferential points to make it easier to cut through the flare cap.
  • lines of weakness can extend in the direction of the edge region and are preferably designed to deflect from the bottom into the flange edge. This results in a simplified overall tear-off of the crimp cap.
  • the crimp cap is preferably provided with at least one line of weakness which extends on the side opposite the tongue from the opening in the direction of its outer edge.
  • the two ends need in the area the separation only to be bent apart with little force, so that the line of weakness tears open from the opening in the direction of the outer edge.
  • the metal foil can be provided with a tear-out tab lying outside the bonding zone, wherein the tear-open tab can consist of a knurled section of the metal foil.
  • the bonding zone in the area of the tear-open tab is designed in such a way that the metal foil can be easily lifted off without the risk of tearing off the tear-open tab without the opening of the floor being subsequently exposed.
  • the film used can have a thickness of 8 to 35 ⁇ m, preferably 15 to 23 ⁇ m.
  • Fig. 1 a medication bottle closed by the closure according to the invention is shown in longitudinal section.
  • FIG. 2 shows a top view of the closure according to FIG. 1.
  • FIG. 3 the crimp cap contained in the closure of FIGS. 1 and 2 in plan view.
  • a closure for a medication bottle 1 is shown, which essentially consists of a sealing element 3 made of polymeric material, which is pressed by a metallic crimp cap 4 onto the mouth 2 of the medication bottle 1.
  • the bottom 5 of the crimp cap 4 is provided with a central opening 6, which is flanged in its edge region 7 in the direction of the outer circumference and the sealing element 3.
  • the annular bottom 5 of the crimp cap 4 thus has a smooth surface and the boundary of the opening 6 is rounded to reduce the risk of injury to the operating personnel.
  • the opening 6 is sealed in a germ-free manner by a metal foil 13 glued to the base 5.
  • the metal foil 13 is circular in the region of its outer circumference.
  • the bonding zone 14 extends circumferentially and is designed in a ring shape.
  • the bottom 5 of the crimp cap 4 comprises a tongue 10 which is fixed with its tongue foot 11 to the crimp cap 4 and projects with its tongue tip 12 into the opening 6.
  • the tongue base 11 is formed with sharp edges in the region of its transition into the bottom 5 of the crimp cap 4, the surface the entire tongue 10 is provided in this embodiment as part of the bonding zone 14.
  • the tear-open tab 18 is delimited by the bonding zone 14, which runs on the side opposite the tongue 10 in a circumferential partial area from the outer circumference of the crimp cap 4 in the direction of the opening 6 and back again in the direction of the outer circumference.
  • the area of the bonding zone 14 is smaller in the area of the tear-open tab 18 than along the outer circumference of the metal foil 13.
  • the crimp cap 4 is provided with lines of weakness 16 which, starting from the opening 6, extend in the direction of the outer edge 17 of the base 5. The entire closure can thereby be completely removed from the medication bottle 1 using small forces.
  • the lines of weakness consist of a notch in the deep-drawn sheet forming the crimp cap, which has a wedge-shaped profile.
  • the metal foil 13 is pulled up at its knurled section 19 in the direction of the tongue 10. If the opening 6 is completely exposed, the content of the medication bottle 1 can be removed, for example, by a syringe. If the film is moved further in the opening direction, the tongue 10 is first bent up slightly until the material of the crimp cap 4 enters the flange projection along the weakening lines 16 via the outer edge 17 in the region of the sharp-edged circumferential points 8, 9. Depending on the design of the Lines of weakness 16 result when the metal foil 13 is pulled off completely, and the crimp cap 4 is severed in at least one area from the opening.
  • a further weakening line 16 is provided on the side of the crimp cap 4 opposite the tongue 10 in the region of the base 5, the ends in the area of the severing are bent apart around the film hinge-like joint on the side opposite the tongue 10 to remove the entire crimp cap 4, until the entire stopper can be easily lifted off the bottle neck.
  • the closure according to the invention seals the content of the medication bottle 1, if need be, even over long periods of time germ-free from the surroundings and is simple and economical to produce.
  • the closure is easy to use by the operating personnel.
  • Fig. 3 shows the crimp cap 4 contained in the closure of FIGS. 1 and 2 in plan view.
  • the crimp cap consists of a deep-drawn aluminum sheet which is provided with a curl in the area surrounding the opening in order to reduce the risk of injury after the metal foil has been removed.
  • the crimp cap is provided in the edge region of the recess on both sides of the tongue 10 and the tongue radially opposite each with a radial notch, which is continued in the lines of weakness 16. All lines of weakness are wedge-shaped. The tongue can thus be removed relatively easily from the crimp cap, which is torn open in the circumferential direction. The remaining part can then be slightly bent in the circumferential direction and removed from the medication bottle.
  • the tongue is extended so far that it mainly fills the opening in the crimp cap 4.
  • the sealing element 4 is protected in a particularly good manner against unintentional damage and an inseparable connection between the metal foil and the tongue is easily accessible.
  • the position of the bond zone is indicated below by a cross-hatching in the top view. It can be seen in the upper illustration how when opening the closure the metal foil in the left part of the left illustration is first touched and raised in an unsealed area until the opening in the crimp cap is completely exposed.
  • the tongue bends in the area of the tongue foot, and the medication can be removed after the piercing of the sealing element 4 by an injection needle.
  • the upper right illustration shows how the crimp cap tears to the right in the edge area when the metal foil connected to the tongue is subsequently pivoted further and is finally severed completely.
  • the tongue and the metal foil are separated from the crimp cap.
  • the part of the crimp cap remaining on the medication bottle can then be opened to the left in the manner indicated in the top view at the bottom right and from the medication bottle. This also frees the sealing element and can be disposed of separately.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP19930113459 1992-12-05 1993-08-24 Verschluss für eine Medikamentenflasche Expired - Lifetime EP0601283B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4241009 1992-12-05
DE19924241009 DE4241009C1 (de) 1992-12-05 1992-12-05 Verschluß für eine Medikamentenflasche

Publications (2)

Publication Number Publication Date
EP0601283A1 EP0601283A1 (de) 1994-06-15
EP0601283B1 true EP0601283B1 (de) 1996-03-06

Family

ID=6474500

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19930113459 Expired - Lifetime EP0601283B1 (de) 1992-12-05 1993-08-24 Verschluss für eine Medikamentenflasche

Country Status (5)

Country Link
EP (1) EP0601283B1 (da)
JP (1) JP2736218B2 (da)
DE (2) DE4241009C1 (da)
DK (1) DK0601283T3 (da)
ES (1) ES2086840T3 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4430741A1 (de) * 1994-08-30 1996-03-07 Helvoet Pharma Aufreißbare Kapsel für flaschenförmige Behälter
DE10127823C1 (de) * 2001-06-07 2002-08-22 West Pharm Serv Drug Res Ltd Verschluss für eine Medikamentenflasche sowie Verfahren zu dessen Herstellung
DE102007038062B3 (de) * 2007-08-11 2009-04-02 Bimed Teknik A.S., Büyükcekmece Verschlusselement für eine Ampulle zur Aufnahme von Flüssigkeiten und Ampulle mit einem solchen Verschlusselement

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1587078A (da) * 1968-08-01 1970-03-13
DE7143101U (de) * 1971-11-16 1972-02-24 Vorkauf H Kuehlrohrwand fuer waermetauscher
US3834579A (en) * 1973-03-27 1974-09-10 American Can Co Container having a metal overcap-thermoplastic lid closure assembly
GB1524548A (en) * 1975-04-18 1978-09-13 Nissin Shokuhin Kaisha Ltd Food receptacle with a peelable and pierceable lid
JPS5666440A (en) * 1979-11-02 1981-06-04 Toyota Motor Corp Piston valve controller for constant negative pressure type carburetor
FR2516480B1 (fr) * 1981-11-13 1986-03-07 Lyonnaise Bouchage Moyens de bouchage d'un recipient contenant des produits a injecter
CH654500A5 (de) * 1982-02-10 1986-02-28 Fischer Ag Georg Dauerform mit mindestens zwei nebeneinander angeordneten formhohlraeumen.
DE3628953A1 (de) * 1986-08-26 1988-03-03 Wuennerlein & Co Fritz Boerdelklappenverschluss
IT213756Z2 (it) * 1988-04-18 1990-02-16 Capsulit Srl Cappuccio di sigillo particolarmente per flaconi di antibiotici e di infusione e trasfusione.
DE3909590A1 (de) * 1989-03-23 1990-09-27 Pharma Metall Gmbh Verschluss fuer medikamentenflaschen und verfahren zum herstellen dieses verschlusses
DE8906346U1 (de) * 1989-05-23 1989-09-14 Pharma-Gummi Wimmer West Gmbh, 5180 Eschweiler Verschluß für Medikamentenflaschen
JP2931993B2 (ja) * 1990-06-25 1999-08-09 日本クラウンコルク株式会社 容器蓋

Also Published As

Publication number Publication date
DE4241009C1 (de) 1994-02-17
DE59301797D1 (de) 1996-04-11
JPH06211297A (ja) 1994-08-02
JP2736218B2 (ja) 1998-04-02
DK0601283T3 (da) 1996-06-24
EP0601283A1 (de) 1994-06-15
ES2086840T3 (es) 1996-07-01

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