EP0601283B1 - Closure for a medicin bottle - Google Patents

Closure for a medicin bottle Download PDF

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Publication number
EP0601283B1
EP0601283B1 EP19930113459 EP93113459A EP0601283B1 EP 0601283 B1 EP0601283 B1 EP 0601283B1 EP 19930113459 EP19930113459 EP 19930113459 EP 93113459 A EP93113459 A EP 93113459A EP 0601283 B1 EP0601283 B1 EP 0601283B1
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EP
European Patent Office
Prior art keywords
tongue
opening
metal foil
closure
crimp cap
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Expired - Lifetime
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EP19930113459
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German (de)
French (fr)
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EP0601283A1 (en
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Pohl GmbH and Co KG
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Pohl GmbH and Co KG
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Publication of EP0601283A1 publication Critical patent/EP0601283A1/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Definitions

  • the invention relates to a closure for a medication bottle, comprising a sealing element which can be placed on the mouth of the medication bottle and is made of polymeric material and is pressed against the mouth by a metallic crimp cap, the crimp cap being provided with an opening in the region of its base and in the edge region on at least one Circumferential point is severable.
  • Such a closure is known from DE-PS 32 41 283.
  • the closure comprises a closure plug made of a deformable, elastic material which can be penetrated by a needle and a ring made of plastic which presses the closure plug onto the mouth of the container under axial pretension.
  • the ring is crimped onto the bottle neck and has a central passage opening which is covered by a pull-out cover.
  • the cover is fastened tightly and tearably on the ring.
  • This configuration is intended on the one hand to ensure a germ-free seal and, on the other hand, that users perceive destruction or removal of the cover immediately. It should be noted, however, that the manufacture of such a closure is unsatisfactory from a manufacturing and economic point of view. A germ-free seal between the cover and the sealing plug is only guaranteed if the closure is manufactured with high precision. Especially the storage of the drug over long periods of time is problematic because the ring shows signs of relaxation over time has and a perfect seal is therefore not guaranteed.
  • the invention has for its object to develop a closure of the type mentioned in such a way that it seals the drug bottle to be sealed over a long period of use and is inexpensive to manufacture in terms of production technology and economy.
  • the closure should also be able to be used with small bottle diameters, the bottle neck of which has a diameter of less than 20 mm.
  • the crimp cap of the closure has a tongue protruding into the opening, with a tongue base which is at least sharply delimited at the circumferential point relative to the crimp cap and with a tongue tip which is inseparably attached to a metal foil which covers the opening in its entirety and is germ-free sealing. wherein the metal foil on the opposite side of the tongue is manually lifted and designed to be removable from the opening in the direction of the tongue.
  • the handling of such a closure is particularly simple.
  • the metal foil is formed, for example, by an aluminum foil which is fastened in the region of the annular bottom on the crimp cap, which can be made of aluminum, for example.
  • the metal foil In order to expose the opening and the sealing element made of flexible, polymeric material underneath, the metal foil is pulled off in the direction of the tongue, so that the contents of the medication bottle are then removed with the help of an injection needle, which holds the sealing element penetrates, can be removed.
  • the metal foil and the crimp cap are inseparably connected in the area of the tongue, which makes it possible to pull the metal foil further in the tear-open direction over the opening to remove the closure from the medication bottle and together with the tongue over the edge region of the base and the flange edge adjoining in the axial direction to separate from the crimp cap.
  • the crimp cap which is then radially severed at a circumferential point can then be removed from the bottle neck without any problems and, like the freely accessible sealing element, can be recycled.
  • the metal foil and the tip of the tongue can be connected by an adhesive zone.
  • the adhesive force of the adhesive and the material thickness of the crimp cap are to be matched to one another in such a way that a separation of the crimp cap is ensured without the bond between the metal foil and the tip of the tongue being released.
  • a hot melt adhesive is preferably used as the adhesive. This can cover the film and / or the material forming the crimp cap in the manner of a film and, for activation in a manner known per se, be temporarily heated to the required extent and solidified by subsequent cooling. The use of a heated pressure die or vibration welding is preferred in the present case.
  • the bonding zone can be provided with an extension that surrounds the opening in a ring-shaped manner in order to ensure a germ-free sealing of the closure on the medication bottle.
  • the bonding zone is in the area of the extension is dimensioned very narrow and is possibly designed only in the manner of a line train.
  • An embodiment in which the adhesive zone in the area surrounding the opening consists of mutually adjacent adhesive points is also possible and in many cases sufficient if the storage and use of the medication bottle is subject to strict control.
  • the microbicidal properties of the metal also result in a barrier effect against penetrating pathogens in the area of an atrium. Under normal hygienic conditions, sufficient sterility of the central area of the opening can often be ensured during a normal storage period, with the tear-open process being considerably easier.
  • the metal foil preferably has a shape adapted to the shape of the crimp cap.
  • the edge region of the base which delimits the opening, can be flanged inwards and in the direction of the outer circumference, the flanging being sharp-edged in the region of the circumferential points to make it easier to cut through the flare cap.
  • lines of weakness can extend in the direction of the edge region and are preferably designed to deflect from the bottom into the flange edge. This results in a simplified overall tear-off of the crimp cap.
  • the crimp cap is preferably provided with at least one line of weakness which extends on the side opposite the tongue from the opening in the direction of its outer edge.
  • the two ends need in the area the separation only to be bent apart with little force, so that the line of weakness tears open from the opening in the direction of the outer edge.
  • the metal foil can be provided with a tear-out tab lying outside the bonding zone, wherein the tear-open tab can consist of a knurled section of the metal foil.
  • the bonding zone in the area of the tear-open tab is designed in such a way that the metal foil can be easily lifted off without the risk of tearing off the tear-open tab without the opening of the floor being subsequently exposed.
  • the film used can have a thickness of 8 to 35 ⁇ m, preferably 15 to 23 ⁇ m.
  • Fig. 1 a medication bottle closed by the closure according to the invention is shown in longitudinal section.
  • FIG. 2 shows a top view of the closure according to FIG. 1.
  • FIG. 3 the crimp cap contained in the closure of FIGS. 1 and 2 in plan view.
  • a closure for a medication bottle 1 is shown, which essentially consists of a sealing element 3 made of polymeric material, which is pressed by a metallic crimp cap 4 onto the mouth 2 of the medication bottle 1.
  • the bottom 5 of the crimp cap 4 is provided with a central opening 6, which is flanged in its edge region 7 in the direction of the outer circumference and the sealing element 3.
  • the annular bottom 5 of the crimp cap 4 thus has a smooth surface and the boundary of the opening 6 is rounded to reduce the risk of injury to the operating personnel.
  • the opening 6 is sealed in a germ-free manner by a metal foil 13 glued to the base 5.
  • the metal foil 13 is circular in the region of its outer circumference.
  • the bonding zone 14 extends circumferentially and is designed in a ring shape.
  • the bottom 5 of the crimp cap 4 comprises a tongue 10 which is fixed with its tongue foot 11 to the crimp cap 4 and projects with its tongue tip 12 into the opening 6.
  • the tongue base 11 is formed with sharp edges in the region of its transition into the bottom 5 of the crimp cap 4, the surface the entire tongue 10 is provided in this embodiment as part of the bonding zone 14.
  • the tear-open tab 18 is delimited by the bonding zone 14, which runs on the side opposite the tongue 10 in a circumferential partial area from the outer circumference of the crimp cap 4 in the direction of the opening 6 and back again in the direction of the outer circumference.
  • the area of the bonding zone 14 is smaller in the area of the tear-open tab 18 than along the outer circumference of the metal foil 13.
  • the crimp cap 4 is provided with lines of weakness 16 which, starting from the opening 6, extend in the direction of the outer edge 17 of the base 5. The entire closure can thereby be completely removed from the medication bottle 1 using small forces.
  • the lines of weakness consist of a notch in the deep-drawn sheet forming the crimp cap, which has a wedge-shaped profile.
  • the metal foil 13 is pulled up at its knurled section 19 in the direction of the tongue 10. If the opening 6 is completely exposed, the content of the medication bottle 1 can be removed, for example, by a syringe. If the film is moved further in the opening direction, the tongue 10 is first bent up slightly until the material of the crimp cap 4 enters the flange projection along the weakening lines 16 via the outer edge 17 in the region of the sharp-edged circumferential points 8, 9. Depending on the design of the Lines of weakness 16 result when the metal foil 13 is pulled off completely, and the crimp cap 4 is severed in at least one area from the opening.
  • a further weakening line 16 is provided on the side of the crimp cap 4 opposite the tongue 10 in the region of the base 5, the ends in the area of the severing are bent apart around the film hinge-like joint on the side opposite the tongue 10 to remove the entire crimp cap 4, until the entire stopper can be easily lifted off the bottle neck.
  • the closure according to the invention seals the content of the medication bottle 1, if need be, even over long periods of time germ-free from the surroundings and is simple and economical to produce.
  • the closure is easy to use by the operating personnel.
  • Fig. 3 shows the crimp cap 4 contained in the closure of FIGS. 1 and 2 in plan view.
  • the crimp cap consists of a deep-drawn aluminum sheet which is provided with a curl in the area surrounding the opening in order to reduce the risk of injury after the metal foil has been removed.
  • the crimp cap is provided in the edge region of the recess on both sides of the tongue 10 and the tongue radially opposite each with a radial notch, which is continued in the lines of weakness 16. All lines of weakness are wedge-shaped. The tongue can thus be removed relatively easily from the crimp cap, which is torn open in the circumferential direction. The remaining part can then be slightly bent in the circumferential direction and removed from the medication bottle.
  • the tongue is extended so far that it mainly fills the opening in the crimp cap 4.
  • the sealing element 4 is protected in a particularly good manner against unintentional damage and an inseparable connection between the metal foil and the tongue is easily accessible.
  • the position of the bond zone is indicated below by a cross-hatching in the top view. It can be seen in the upper illustration how when opening the closure the metal foil in the left part of the left illustration is first touched and raised in an unsealed area until the opening in the crimp cap is completely exposed.
  • the tongue bends in the area of the tongue foot, and the medication can be removed after the piercing of the sealing element 4 by an injection needle.
  • the upper right illustration shows how the crimp cap tears to the right in the edge area when the metal foil connected to the tongue is subsequently pivoted further and is finally severed completely.
  • the tongue and the metal foil are separated from the crimp cap.
  • the part of the crimp cap remaining on the medication bottle can then be opened to the left in the manner indicated in the top view at the bottom right and from the medication bottle. This also frees the sealing element and can be disposed of separately.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Description

Die Erfindung betrifft einen Verschluß für eine Medikamentenflasche, umfassend ein auf die Mündung der Medikamentenflasche aufsetzbares Dichtelement aus polymerem Werkstoff, das von einer metallischen Bördelkappe an die Mündung angepreßt wird, wobei die Bördelkappe im Bereich ihres Bodens mit einer Durchbrechung versehen und im Randbereich an wenigstens einer Umfangsstelle durchtrennbar ist.The invention relates to a closure for a medication bottle, comprising a sealing element which can be placed on the mouth of the medication bottle and is made of polymeric material and is pressed against the mouth by a metallic crimp cap, the crimp cap being provided with an opening in the region of its base and in the edge region on at least one Circumferential point is severable.

Ein derartiger Verschluß ist aus der DE-PS 32 41 283 bekannt. Der Verschluß umfaßt einen Verschlußstopfen aus einem verformbaren, elastischen und von einer Nadel durchdringbaren Material und einen Ring aus Kunststoff, der den Verschlußstopfen unter axialer Vorspannung auf die Mündung des Behälters drückt. Der Ring wird auf den Flaschenhals aufgebördelt und weist eine zentrale Durchtrittsöffnung auf, die von einem ausreißbaren Deckel überdeckt ist. Zur Vermeidung von Verunreinigungen der Oberfläche des Verschlußstopfens ist der Deckel am Ring dicht und abreißbar befestigt. Durch diese Ausgestaltung soll einerseits eine keimfreie Abdichtung gewährleistet sein und andererseits eine Zerstörung oder Entfernung des Deckels Benutzer sofort wahrgenommen werden. Dabei ist allerdings zu beachten, daß die Herstellung eines derartigen Verschlusses in fertigungstechnischer und wirtschaftlicher Hinsicht wenig befriedigend ist. Eine keimfreie Abdichtung zwischen dem Deckel und dem Verschlußstopfen ist nur dann gewahrleistet, wenn der Verschluß mit hoher Präzision hergestellt ist. Insbesondere die Aufbewahrung des Medikaments über längere Zeiträume ist problematisch, da der Ring im Laufe der Zeit Relaxationserscheinungen aufweist und eine einwandfreie Abdichtung daher nicht sicher gewährleistet ist.Such a closure is known from DE-PS 32 41 283. The closure comprises a closure plug made of a deformable, elastic material which can be penetrated by a needle and a ring made of plastic which presses the closure plug onto the mouth of the container under axial pretension. The ring is crimped onto the bottle neck and has a central passage opening which is covered by a pull-out cover. In order to avoid contamination of the surface of the sealing plug, the cover is fastened tightly and tearably on the ring. This configuration is intended on the one hand to ensure a germ-free seal and, on the other hand, that users perceive destruction or removal of the cover immediately. It should be noted, however, that the manufacture of such a closure is unsatisfactory from a manufacturing and economic point of view. A germ-free seal between the cover and the sealing plug is only guaranteed if the closure is manufactured with high precision. Especially the storage of the drug over long periods of time is problematic because the ring shows signs of relaxation over time has and a perfect seal is therefore not guaranteed.

Der Erfindung liegt die Aufgabe zugrunde, einen Verschluß der eingangs genannten Art derart weiterzuentwickeln, daß er die abzudichtende Medikamentenflasche während einer langen Gebrauchsdauer abdichtet und in fertigungstechnischer und wirtschaftlicher Hinsicht günstig herstellbar ist. Außerdem soll der Verschluß auch bei kleinen Flaschendurchmessern zur Anwendung gelangen können, deren Flaschenhals einen Durchmesser von weniger als 20 mm aufweist.The invention has for its object to develop a closure of the type mentioned in such a way that it seals the drug bottle to be sealed over a long period of use and is inexpensive to manufacture in terms of production technology and economy. In addition, the closure should also be able to be used with small bottle diameters, the bottle neck of which has a diameter of less than 20 mm.

Diese Aufgabe wird erfindungsgemäß mit den Merkmalen von Anspruch 1 gelöst. Auf vorteilhafte Ausgestaltungen nehmen die Unteransprüche Bezug.This object is achieved with the features of claim 1. The subclaims refer to advantageous refinements.

Die Bördelkappe des Verschlusses weist eine in die Durchbrechung vorspringende Zunge auf, mit einem Zungenfuß, der zumindest an der Umfangsstelle scharfkantig gegenüber der Bördelkappe begrenzt ist sowie mit einer Zungenspitze, die an einer die Durchbrechung in ihrer Gesamtheit überdeckenden und keimfrei abdichtenden Metallfolie unlösbar festgelegt ist, wobei die Metallfolie auf der der Zunge gegenüberliegenden Seite manuell abhebbar und in Richtung der Zunge von der Durchbrechung abziehbar gestaltet ist. Die Handhabung eines derartigen Verschlusses ist besonders einfach. Die Metallfolie ist beispielsweise durch eine Aluminiumfolie gebildet, die im Bereich des kreisringförmigen Bodens auf der Bördelkappe, die beispielsweise aus Aluminium bestehen kann, befestigt ist. Um die Durchbrechung und das darunter angeordnete Dichtelement aus weichelastischem, polymerem Werkstoff freizulegen, wird die Metallfolie in Richtung der Zunge abgezogen, so daß anschließend der Inhalt der Medikamentenflasche mit Hilfe einer Injektionsnadel, die das Dichtelement durchdringt, entnommen werden kann. Die Metallfolie und die Bördelkappe sind im Bereich der Zunge unlösbar verbundenden, wodurch es möglich ist, die Metallfolie zum Entfernen des Verschlusses von der Medikamentenflasche in Aufreißrichtung über die Durchbrechung weiterzuziehen und zusammen mit der Zunge über den Randbereich des Bodens und den in axialer Richtung angrenzenden Flanschrand aus der Bördelkappe herauszutrennen. Die anschließend an einer Umfangsstelle radial durchtrennte Bördelkappe kann dann problemlos vom Flaschenhals entfernt und ebenso wie das frei zugängliche Dichtelement der Wiederverwertung zugeführt werden.The crimp cap of the closure has a tongue protruding into the opening, with a tongue base which is at least sharply delimited at the circumferential point relative to the crimp cap and with a tongue tip which is inseparably attached to a metal foil which covers the opening in its entirety and is germ-free sealing. wherein the metal foil on the opposite side of the tongue is manually lifted and designed to be removable from the opening in the direction of the tongue. The handling of such a closure is particularly simple. The metal foil is formed, for example, by an aluminum foil which is fastened in the region of the annular bottom on the crimp cap, which can be made of aluminum, for example. In order to expose the opening and the sealing element made of flexible, polymeric material underneath, the metal foil is pulled off in the direction of the tongue, so that the contents of the medication bottle are then removed with the help of an injection needle, which holds the sealing element penetrates, can be removed. The metal foil and the crimp cap are inseparably connected in the area of the tongue, which makes it possible to pull the metal foil further in the tear-open direction over the opening to remove the closure from the medication bottle and together with the tongue over the edge region of the base and the flange edge adjoining in the axial direction to separate from the crimp cap. The crimp cap which is then radially severed at a circumferential point can then be removed from the bottle neck without any problems and, like the freely accessible sealing element, can be recycled.

Die Metallfolie und die Zungenspitze können durch eine Verklebungszone verbunden sein. Die Haftkraft des Klebstoffes und die Materialstärke der Bördelkappe sind dabei so aufeinander abzustimmen, daß eine Durchtrennung der Bördelkappe gewährleistet ist, ohne daß sich die Verklebung zwischen der Metallfolie und der Zungenspitze löst. Als Kleber gelangt bevorzugt ein Schmelzkleber zur Anwendung. Dieser kann die Folie und/oder den die Bördelkappe bildenden Werkstoff nach Art eines Films überziehen und und zur Aktivierung auf an sich bekannte Weise im erforderlichen Maße vorübergehend erwärmt und durch nachfolgende Abkühlung verfestigt werden. Die Verwendung eines erwärmten Andrückstempels oder des Fibrationsschweißens wird vorliegend bevorzugt.The metal foil and the tip of the tongue can be connected by an adhesive zone. The adhesive force of the adhesive and the material thickness of the crimp cap are to be matched to one another in such a way that a separation of the crimp cap is ensured without the bond between the metal foil and the tip of the tongue being released. A hot melt adhesive is preferably used as the adhesive. This can cover the film and / or the material forming the crimp cap in the manner of a film and, for activation in a manner known per se, be temporarily heated to the required extent and solidified by subsequent cooling. The use of a heated pressure die or vibration welding is preferred in the present case.

Die Verklebungszone kann mit einer die Durchbrechung ringförmig umschließenden Erweiterung versehen sein, um eine keimfreie Abdichtung des Verschlusses auf der Medikamentenflasche zu gewährleisten. Um dennoch eine leichte Handhabung während des Aufreißens der Folie sicherzustellen, hat es sich als vorteilhaft bewährt, wenn die Verklebungszone im Bereich der Erweiterung sehr schmal dimensioniert wird und gegebenenfalls nur nach Art eines Linienzuges gestaltet ist. Eine Ausbildung, bei der die Verklebungzone in dem die Druchbrechung umschließenden Bereich aus einander benachbarten Verklebungspunkten besteht ist ebenfalls möglich und vielfach ausreichend, wenn die Lagerung und Verwendung der Medikamentenflasche einer stregen Kontrolle unterliegt. Außerdem ergibt sich im Dichtspalt, wenn dieser auf einer Seite durch eine freie Metallfläche begrenzt ist, aufgrund der mikrobiziden Eigenschaften des Metalls auch im Bereich eines Vorhofs eine Sperrwirkung gegenüber eindringenden Erregern. Unter üblichen hygienischen Verhältnissen läßt sich hierdurch während einer normalen Lagerdauer häufig eine ausreichende Sterilität des Zentralbereichs der Durchbrechung gewährleisten bei einer erheblichen Erleichtetung des Aufreißvorganges.The bonding zone can be provided with an extension that surrounds the opening in a ring-shaped manner in order to ensure a germ-free sealing of the closure on the medication bottle. In order to ensure easy handling while the film is being torn open, it has proven to be advantageous if the bonding zone is in the area of the extension is dimensioned very narrow and is possibly designed only in the manner of a line train. An embodiment in which the adhesive zone in the area surrounding the opening consists of mutually adjacent adhesive points is also possible and in many cases sufficient if the storage and use of the medication bottle is subject to strict control. In addition, in the sealing gap, if this is delimited on one side by a free metal surface, the microbicidal properties of the metal also result in a barrier effect against penetrating pathogens in the area of an atrium. Under normal hygienic conditions, sufficient sterility of the central area of the opening can often be ensured during a normal storage period, with the tear-open process being considerably easier.

Die Metallfolie weist bevorzugt eine an die Form der Bördelkappe angepaßte Gestalt auf. Um die Verletzungsgefahr zu minimieren kann der Randbereich des Bodens, der die Durchbrechung begrenzt, nach innen und in Richtung des Außenumfangs umgebördelt sein, wobei die Umbördelung im Bereich der Umfangsstellen zur leichteren Durchtrennung der Bördelkappe scharfkantig ausgebildet ist. Von den Umfangsstellen ausgehend, können sich Schwächungslinien in Richtung des Randbereichs erstrecken und sind bevorzugt vom Boden in den Flanschrand umlenkend ausgebildet. Ein vereinfachter Gesamtabriß der Bördelkappe ist dadurch bedingt. Die Bördelkappe ist bevorzugt mit zumindest einer Schwächungslinie versehen, die sich auf der der Zunge gegenüberliegenden Seite von der Durchbrechung in Richtung ihres Außenrandes erstreckt. Ist die Bördelkappe durch ein vollständiges Abziehen der Metallfolie in einem Teilbereich ihres Umfanges aufgetrennt brauchen die beiden Enden im Bereich der Auftrennung nur noch mit geringer Kraft auseinandergebogen zu werden, so daß die Schwächungslinie von der Durchbrechung ausgehend in Richtung des Außenrandes aufreißt. Der Bereich des Kappenrandes, der der Zunge gegenüberliegt, bildet ein filmscharnierartiges Gelenk, das den Drehpunkt beim Aufbiegen der beiden Enden bildet. Nach dem Ausreißen der Zunge aus der Bördelkappe kann diese leicht in Umfangsrichtung aufgebogen und problemlos vom Flaschenhals entnommen werden.The metal foil preferably has a shape adapted to the shape of the crimp cap. In order to minimize the risk of injury, the edge region of the base, which delimits the opening, can be flanged inwards and in the direction of the outer circumference, the flanging being sharp-edged in the region of the circumferential points to make it easier to cut through the flare cap. Starting from the circumferential points, lines of weakness can extend in the direction of the edge region and are preferably designed to deflect from the bottom into the flange edge. This results in a simplified overall tear-off of the crimp cap. The crimp cap is preferably provided with at least one line of weakness which extends on the side opposite the tongue from the opening in the direction of its outer edge. If the crimp cap is separated in a partial area of its circumference by completely pulling off the metal foil, the two ends need in the area the separation only to be bent apart with little force, so that the line of weakness tears open from the opening in the direction of the outer edge. The area of the edge of the cap, which lies opposite the tongue, forms a hinge-like hinge, which forms the fulcrum when the two ends are bent open. After the tongue has been torn out of the crimp cap, it can be easily bent open in the circumferential direction and easily removed from the bottle neck.

Zur Erleichterung des Abhebens der Metallfolie kann diese mit einer außerhalb der Verklebungszone liegenden Ausreißlasche versehen sein, wobei die Aufreißlasche aus einem gerändelten Abschnitt der Metallfolie bestehen kann. Die Verklebungszone im Bereich der Aufreißlasche ist derart ausgebildet, daß die Metallfolie leicht abgehoben werden kann, ohne daß die Gefahr besteht, die Aufreißlasche abzureißen, ohne daß anschließend die Durchbrechung des Bodens freigelegt ist.To make it easier to lift off the metal foil, it can be provided with a tear-out tab lying outside the bonding zone, wherein the tear-open tab can consist of a knurled section of the metal foil. The bonding zone in the area of the tear-open tab is designed in such a way that the metal foil can be easily lifted off without the risk of tearing off the tear-open tab without the opening of the floor being subsequently exposed.

In dieser Hinsicht hat es sich als vorteilhaft bewährt, wenn die Verklebungszone von der Aufreißlasche ausgehend umfangsseitig in Richtung der Zunge in ihrer Fläche erweitert ist. Diese Maßnahme bedingt gute Gebrauchseigenschaften sowohl hinsichtlich eines leichten Öffnens der Durchbrechung und eines sicheren Durchtrennens der Bördelkappe zur vollständigen Entfernung des Verschlusses von der Medikamentenflasche.In this regard, it has proven to be advantageous if the area of the bonded zone, starting from the tear-open tab, is widened in the direction of the tongue. This measure requires good usage properties both with regard to easy opening of the opening and safe severing of the crimp cap in order to completely remove the closure from the medication bottle.

Die zur Anwendung gelangende Folie kann eine Dicke von 8 bis 35 µm, bevorzugt von 15 bis 23 µm aufweisen.The film used can have a thickness of 8 to 35 μm, preferably 15 to 23 μm.

Ein Ausführungsbeispiel eines erfindungsgemäßen Verschlusses wird nachfolgend unter Bezugnahme auf die beigefügten Zeichnungen näher erläutert.An embodiment of a closure according to the invention is explained in more detail below with reference to the accompanying drawings.

In Fig. 1 ist eine durch den erfindungsgemäßen Verschluß verschlossene Medikamentenflasche längsgeschnitten dargestellt.In Fig. 1 a medication bottle closed by the closure according to the invention is shown in longitudinal section.

Fig. 2 zeigt eine Draufsicht auf den Verschluß nach Fig. 1.FIG. 2 shows a top view of the closure according to FIG. 1.

Fig. 3 die in dem Verschluß nach Fig. 1 und 2 enthaltene Bördelkappe in der Draufsicht.Fig. 3, the crimp cap contained in the closure of FIGS. 1 and 2 in plan view.

Fig. 4 und 5 den Prozess des Öffnens und des Abnehmens zweier Ausführungen des Verschlusses.4 and 5 the process of opening and removing two versions of the closure.

In Fig. 1 ist ein Verschluß für eine Medikamentenfalsche 1 gezeigt, der im wesentlichen aus einem Dichtelement 3 aus polymerem Werkstoff besteht, das von einer metallischen Bördelkappe 4 an die Mündung 2 der Medikamentenflasche 1 angepreßt wird. Der Boden 5 der Bördelkappe 4 ist mit einer zentralen Durchbrechung 6 versehen, die in ihrem Randbereich 7 in Richtung des Außenumfangs und dem Dichtelement 3 umgebördelt ist. Der kreisringförmige Boden 5 der Bördelkappe 4 weist dadurch eine glatte Oberfläche auf und die Begrenzung der Durchbrechung 6 ist gerundet ausgeführt, um die Gefahr von Verletzungen des Bedienungspersonals zu verringern. Die Durchbrechung 6 ist in diesem Ausführungsbeispiel durch eine auf den Boden 5 aufgeklebte Metallfolie 13 keimfrei abgedichtet. Die Metallfolie 13 ist ebenso wie die Bördelkappe 4 im Bereich ihres Außenumfangs kreisförmig ausgebildet. Die Verklebungszone 14 ersteckt sich umfangsseitig und ist ringförmig ausgebildet. Der Boden 5 der Bördelkappe 4 umfaßt eine Zunge 10, die mit ihrem Zungenfuß 11 an der Bördelkappe 4 festgelegt ist und mit ihrer Zungenspitze 12 in die Durchbrechung 6 vorspringt. Der Zungenfuß 11 ist im Bereich seines Übergangs in den Boden 5 der Bördelkappe 4 scharfkantig ausgebildet, wobei die Oberfläche der gesamten Zunge 10 in diesem Ausführungsbeispiel als Teil der Verklebungszone 14 vorgesehen ist. Auf der der Zunge 10 gegenüberliegenden Seite der Bördelkappe 4 ist eine außerhalb der Verklebungszone 14 liegende Aufreißlasche 18 angeordnet, die aus einem gesrändelten Abschnitt 19 der Metallfolie 13 besteht. Die Aufreißlasche 18 wird durch die Verklebungszone 14 begrenzt, die auf der der Zunge 10 gegenüberliegenden Seite in einem umfangsseitigen Teilbereich vom Außenumfang der Bördelkappe 4 in Richtung der Durchbrechung 6 und wieder zurück in Richtung des Außenumfangs verläuft. Die Fläche der Verklebungszone 14 ist im Bereich der Aufreißlasche 18 kleiner als entlang des Außenumfangs der Metallfolie 13.In Fig. 1, a closure for a medication bottle 1 is shown, which essentially consists of a sealing element 3 made of polymeric material, which is pressed by a metallic crimp cap 4 onto the mouth 2 of the medication bottle 1. The bottom 5 of the crimp cap 4 is provided with a central opening 6, which is flanged in its edge region 7 in the direction of the outer circumference and the sealing element 3. The annular bottom 5 of the crimp cap 4 thus has a smooth surface and the boundary of the opening 6 is rounded to reduce the risk of injury to the operating personnel. In this exemplary embodiment, the opening 6 is sealed in a germ-free manner by a metal foil 13 glued to the base 5. Like the crimp cap 4, the metal foil 13 is circular in the region of its outer circumference. The bonding zone 14 extends circumferentially and is designed in a ring shape. The bottom 5 of the crimp cap 4 comprises a tongue 10 which is fixed with its tongue foot 11 to the crimp cap 4 and projects with its tongue tip 12 into the opening 6. The tongue base 11 is formed with sharp edges in the region of its transition into the bottom 5 of the crimp cap 4, the surface the entire tongue 10 is provided in this embodiment as part of the bonding zone 14. On the side of the crimp cap 4 opposite the tongue 10 there is a tear-open tab 18 which lies outside the bonding zone 14 and which consists of a knurled section 19 of the metal foil 13. The tear-open tab 18 is delimited by the bonding zone 14, which runs on the side opposite the tongue 10 in a circumferential partial area from the outer circumference of the crimp cap 4 in the direction of the opening 6 and back again in the direction of the outer circumference. The area of the bonding zone 14 is smaller in the area of the tear-open tab 18 than along the outer circumference of the metal foil 13.

Die Bördelkappe 4 ist mit Schwächungslinien 16 versehen, die sich, ausgehend von der Durchbrechung 6 in Richtung des Außenrandes 17 des Bodens 5 erstrecken. Der gesamte Verschluß kann dadurch unter Einsatz geringer Kräfte vollständig von der Medikamentenflasche 1 abgenommen werden. Die Schwächungslinien bestehen aus einer Einkerbung des die Bördelkappe bildenden, teifgezogenen Bleches, die von keilförmigem Profil ist.The crimp cap 4 is provided with lines of weakness 16 which, starting from the opening 6, extend in the direction of the outer edge 17 of the base 5. The entire closure can thereby be completely removed from the medication bottle 1 using small forces. The lines of weakness consist of a notch in the deep-drawn sheet forming the crimp cap, which has a wedge-shaped profile.

Ausgehend von der manuell abhebbar gestalteten Aufreißlasche 18 wird die Metallfolie 13 an ihrem gerändelten Abschnitt 19 in Richtung der Zunge 10 aufgezogen. Ist die Durchbrechung 6 völlig freigelegt, kann der Inhalt der Medikamentenflasche 1 beispielsweise durch eine Spritze entnommen werden. Wird die Folie in Öffnungsrichtung weiter bewegt, wird zunächst die Zunge 10 etwas aufgebogen, bis im Bereich der scharfkantig ausgebildeten Umfangsstellen 8, 9 das Material der Bördelkappe 4 entlang der Schwächungslinien 16 über den Außenrand 17 in den Flanschvorsprung einreist. Je nach Ausgestaltung der Schwächungslinien 16 ergibt sich bei einem vollständigen Abziehen der Metallfolie 13 eine Durchtrennung der Bördelkappe 4 in zumindest einem Bereich von der Durchbrechung ausgehend. Ist auf der der Zunge 10 gegenüberliegenden Seite der Bördelkappe 4 im Bereich des Bodens 5 eine weitere Schwächungslinie 16 vorgesehen, werden zum Entfernen der gesamten Bördelkappe 4 die Enden im Bereich der Durchtrennung so lange um das filmscharnierartige Gelenk auf der der Zunge 10 gegenüberliegenden Seite auseinandergebogen, bis der gesamte Verschluß problemlos vom Flaschenhals abgehoben werden kann.Starting from the tear-open tab 18, which is designed to be manually liftable, the metal foil 13 is pulled up at its knurled section 19 in the direction of the tongue 10. If the opening 6 is completely exposed, the content of the medication bottle 1 can be removed, for example, by a syringe. If the film is moved further in the opening direction, the tongue 10 is first bent up slightly until the material of the crimp cap 4 enters the flange projection along the weakening lines 16 via the outer edge 17 in the region of the sharp-edged circumferential points 8, 9. Depending on the design of the Lines of weakness 16 result when the metal foil 13 is pulled off completely, and the crimp cap 4 is severed in at least one area from the opening. If a further weakening line 16 is provided on the side of the crimp cap 4 opposite the tongue 10 in the region of the base 5, the ends in the area of the severing are bent apart around the film hinge-like joint on the side opposite the tongue 10 to remove the entire crimp cap 4, until the entire stopper can be easily lifted off the bottle neck.

Der erfindungsgemäße Verschluß dichtet den Inhalt der Medikamentenflasche 1 bedarfsweise auch über lange Zeiträume keimfrei gegen die Umgebung ab und ist einfach und in wirtschaftlicher Hinsicht kostengünstig herstellbar. Der Verschluß ist durch das Bedienungspersonal einfach zu handhaben.The closure according to the invention seals the content of the medication bottle 1, if need be, even over long periods of time germ-free from the surroundings and is simple and economical to produce. The closure is easy to use by the operating personnel.

Fig. 3 zeigt die in dem Verschluß nach Fig. 1 und 2 enthaltene Bördelkappe 4 in der Draufsicht. Hierdurch wird eine Ausführung verdeutlicht, bei der die Bördelkappe aus einem tiefgezogenen Aluminiumblech besteht, welches in dem die Durchbrechung umschließenden Bereich mit einer Einrollung versehen ist um die Verletzungsgefahr nach dem Entfernen der Metallfolie zu vermindern. Die Bördelkappe ist im Randbereich der Ausnehmung beiderseits der Zunge 10 und der Zunge radial gegenüberliegend jeweils mit einer radialen Einkerbung versehen, die in den Schwächungslinien 16 eine Fortsetzung findet. Alle Schwächungslinien sind von keilförmigem Profil. Die Zunge läßt sich dadurch relativ leicht aus der Bördelkappe heraustrennen, wobei diese in Umfangsrichtung aufgerissen wird. Der zurückbleibende Teil kann anschließnd leicht in Umfangsrichtung aufgebogen und von der Medikamentenflasche abgenommen werden.Fig. 3 shows the crimp cap 4 contained in the closure of FIGS. 1 and 2 in plan view. This clarifies an embodiment in which the crimp cap consists of a deep-drawn aluminum sheet which is provided with a curl in the area surrounding the opening in order to reduce the risk of injury after the metal foil has been removed. The crimp cap is provided in the edge region of the recess on both sides of the tongue 10 and the tongue radially opposite each with a radial notch, which is continued in the lines of weakness 16. All lines of weakness are wedge-shaped. The tongue can thus be removed relatively easily from the crimp cap, which is torn open in the circumferential direction. The remaining part can then be slightly bent in the circumferential direction and removed from the medication bottle.

Um diesen Vorgang noch weiter zu erleichtern ist es möglich, die Schwächungslinien über den Randbereich der Deckfläche der Bördelkappe hinausgehend zu verlängern bis zu deren unterer Begrenzung. Beim Heraustrennen der auf die Zunge radial nach außen folgenden Bestandteile aus der Bördelkappe ergibt sich in diesem Falle keine Veränderung des erforderlichen Kraftbedarfs.In order to make this process even easier, it is possible to extend the lines of weakness beyond the edge area of the top surface of the crimp cap up to their lower limit. In this case, when the components following the tongue radially outward are removed from the crimp cap, there is no change in the required force.

Die Fig. 4 und 5 zeigen den Prozess des Öffnes und des Abnehmens zweier unterschiedlich gestalteter Ausführungen des Verschlusses von einer Medikamentenflasche. Bei er Ausführung nach Fig. 4 ist die Zunge soweit verlängert, daß sie die Durchbrechung der Bördelkappe 4 überwiegend ausfüllt. Hierdurch ist das Dichtelement 4 in besonders guter Weise vor unbeabsichtigten Beschädigungen geschützt und eine unlösbare Verbindung zwischen der Metallfolie und der Zunge leicht erreichbar. Die Lage der Verklebungszone ist unter der linken Darstellung durch eine in die Draufsicht eingetragene, sich überkreuzende Schraffur angedeutet. Es ist in der oberen Darstellung zu erkennen, wie beim Öffnen des Verschlusses zunächst die Metallfolie im linken Teil der linken Darstellung in einem unverklebten Teilbereich berührt und angehoben wird, bis die Durchbrechung der Bördelkappe völlig freigelegt ist. Die Zunge knickt dabei im Bereich des Zungenfußes ein, das Medikament kann nach dem Durchstechen des Dichtelementes 4 durch eine Injektionsnadel entnommen werden. In der oberen, rechten Darstellung ist gezeigt, wie die Bördelkappe beim anschließenden Weiterschwenken der mit der Zunge verbundenen Metallfolie nach rechts im Randbereich einreißt und schließlich ganz durchtrennt wird. Die Zunge und die Metallfolie werden dabei von der Bördelkappe getrennt. Der an der Medikamentenflasche zurückbleibende Teil der Bördelkappe kann anschließend in der rechts unten in der Draufsicht angedeuteten Weise nach links aufgeklappt und von der Medikamentenflasche getrennt werden. Das Dichtelement wird dadurch ebenfalls frei und kann gesondert entsorgt werden.4 and 5 show the process of opening and removing two differently designed versions of the closure from a medication bottle. 4, the tongue is extended so far that it mainly fills the opening in the crimp cap 4. As a result, the sealing element 4 is protected in a particularly good manner against unintentional damage and an inseparable connection between the metal foil and the tongue is easily accessible. The position of the bond zone is indicated below by a cross-hatching in the top view. It can be seen in the upper illustration how when opening the closure the metal foil in the left part of the left illustration is first touched and raised in an unsealed area until the opening in the crimp cap is completely exposed. The tongue bends in the area of the tongue foot, and the medication can be removed after the piercing of the sealing element 4 by an injection needle. The upper right illustration shows how the crimp cap tears to the right in the edge area when the metal foil connected to the tongue is subsequently pivoted further and is finally severed completely. The tongue and the metal foil are separated from the crimp cap. The part of the crimp cap remaining on the medication bottle can then be opened to the left in the manner indicated in the top view at the bottom right and from the medication bottle. This also frees the sealing element and can be disposed of separately.

Der vorstehend erläuterte Ablöseprozess wiederholt sich bei Fig. 5 in identischer Weise. Die Metallfolie ist jedoch topfartig gestaltet und auf die Bördelkappe aufgestülpt, wodurch ein besseres Aussehen und eine bessere Verschmutzungssicherheit der Oberseite der Bördelkappe im Randbereich erreicht wird. Unter hygienischen Gesichtspunkten ist das von großem Vorteil wird.The detachment process explained above is repeated in an identical manner in FIG. 5. However, the metal foil is pot-shaped and put on the crimp cap, which results in a better appearance and better protection against contamination of the top of the crimp cap in the edge region. From a hygienic point of view, this is a great advantage.

Claims (6)

  1. A closure for a medicine bottle, comprising a sealing element (3) of polymeric material which can be placed on the mouth of the medicine bottle and can be pressed against the mouth by a metallic flanged cap (4), the flanged cap (4) being provided in the region of its base with an opening (6) and being penetrable in the peripheral region at at least one circumferential point, characterized in that the flanged cap (4) has a tongue (10) projecting into the opening (6) and having a tongue root (11), which at least at the circumferential point (8, 9) is delimited from the flanged cap (4) by a sharp edge, and also having a tongue tip (12), which is fixed undetachably on a metal foil (13) covering the opening (6) in its entirety and sealing it against germs, and in that the metal foil (13) is designed such that, on the side lying opposite the tongue (10), it can be manually lifted off and pulled away from the opening in the direction of the tongue.
  2. A closure according to claim 1, characterized in that the metal foil (13) and the tongue tip (12) are connected by an adhesive bonding zone (14).
  3. A closure according to claim 2, characterized in that the adhesive bonding zone (14) is provided with an extension (15) annularly surrounding the opening (6).
  4. A closure according to any of claims 1 to 3, characterized in that the flanged cap (4) is provided with at least one line of weakness (16), which on the side lying opposite the tongue (10) extends from the opening (6) in the direction of its outer periphery (17).
  5. A closure according to any of claims 1 to 4, characterized in that the metal foil (13) is provided with a tear-open tab (18), lying outside the adhesive bonding zone (14), to facilitate lifting off.
  6. A closure according to claim 5, characterized in that the tear-open tab (18) comprises a crimped portion (19) of the metal foil (13).
EP19930113459 1992-12-05 1993-08-24 Closure for a medicin bottle Expired - Lifetime EP0601283B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4241009 1992-12-05
DE19924241009 DE4241009C1 (en) 1992-12-05 1992-12-05 Closure for a medication bottle

Publications (2)

Publication Number Publication Date
EP0601283A1 EP0601283A1 (en) 1994-06-15
EP0601283B1 true EP0601283B1 (en) 1996-03-06

Family

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Application Number Title Priority Date Filing Date
EP19930113459 Expired - Lifetime EP0601283B1 (en) 1992-12-05 1993-08-24 Closure for a medicin bottle

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EP (1) EP0601283B1 (en)
JP (1) JP2736218B2 (en)
DE (2) DE4241009C1 (en)
DK (1) DK0601283T3 (en)
ES (1) ES2086840T3 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4430741A1 (en) * 1994-08-30 1996-03-07 Helvoet Pharma Tearable capsule for bottle-shaped containers
DE10127823C1 (en) * 2001-06-07 2002-08-22 West Pharm Serv Drug Res Ltd Closure for a medication bottle and process for its manufacture
DE102007038062B3 (en) * 2007-08-11 2009-04-02 Bimed Teknik A.S., Büyükcekmece Sealing element for pharmaceutical phial, has sealing cap for sealing extraction section after extraction of liquid and includes conical stopper section with outer surface that is formed complementary to inner surface of recess

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1587078A (en) * 1968-08-01 1970-03-13
DE7143101U (en) * 1971-11-16 1972-02-24 Vorkauf H COOLING PIPE WALL FOR HEAT EXCHANGER
US3834579A (en) * 1973-03-27 1974-09-10 American Can Co Container having a metal overcap-thermoplastic lid closure assembly
GB1524548A (en) * 1975-04-18 1978-09-13 Nissin Shokuhin Kaisha Ltd Food receptacle with a peelable and pierceable lid
JPS5666440A (en) * 1979-11-02 1981-06-04 Toyota Motor Corp Piston valve controller for constant negative pressure type carburetor
FR2516480B1 (en) * 1981-11-13 1986-03-07 Lyonnaise Bouchage MEANS FOR SEALING A CONTAINER CONTAINING PRODUCTS FOR INJECTION
CH654500A5 (en) * 1982-02-10 1986-02-28 Fischer Ag Georg PERMANENT MOLD WITH AT LEAST TWO MOLDING CAVIES ARRANGED SIDE BY EACH OTHER.
DE3628953A1 (en) * 1986-08-26 1988-03-03 Wuennerlein & Co Fritz Flanged cap closure
IT213756Z2 (en) * 1988-04-18 1990-02-16 Capsulit Srl SEAL HOOD PARTICULARLY FOR BOTTLES OF ANTIBIOTICS AND INFUSION AND TRANSFUSION.
DE3909590A1 (en) * 1989-03-23 1990-09-27 Pharma Metall Gmbh CLOSURE FOR MEDICINAL BOTTLES AND METHOD FOR PRODUCING THIS CLOSURE
DE8906346U1 (en) * 1989-05-23 1989-09-14 Pharma-Gummi Wimmer West Gmbh, 5180 Eschweiler Closure for medicine bottles
JP2931993B2 (en) * 1990-06-25 1999-08-09 日本クラウンコルク株式会社 Container lid

Also Published As

Publication number Publication date
DE4241009C1 (en) 1994-02-17
DE59301797D1 (en) 1996-04-11
JPH06211297A (en) 1994-08-02
JP2736218B2 (en) 1998-04-02
DK0601283T3 (en) 1996-06-24
EP0601283A1 (en) 1994-06-15
ES2086840T3 (en) 1996-07-01

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