EP0589927A1 - Geschützter aminosäurebaustein, herstellung und verwendung - Google Patents

Geschützter aminosäurebaustein, herstellung und verwendung

Info

Publication number
EP0589927A1
EP0589927A1 EP92911418A EP92911418A EP0589927A1 EP 0589927 A1 EP0589927 A1 EP 0589927A1 EP 92911418 A EP92911418 A EP 92911418A EP 92911418 A EP92911418 A EP 92911418A EP 0589927 A1 EP0589927 A1 EP 0589927A1
Authority
EP
European Patent Office
Prior art keywords
amino acid
building block
amino
group
protected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92911418A
Other languages
German (de)
English (en)
French (fr)
Inventor
Ralf Bartl
Ronald Frank
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
Original Assignee
Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helmholtz Zentrum fuer Infektionsforschung HZI GmbH filed Critical Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
Publication of EP0589927A1 publication Critical patent/EP0589927A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP92911418A 1991-06-13 1992-06-05 Geschützter aminosäurebaustein, herstellung und verwendung Withdrawn EP0589927A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4119544 1991-06-13
DE19914119544 DE4119544C1 (enrdf_load_stackoverflow) 1991-06-13 1991-06-13
PCT/EP1992/001280 WO1992022566A1 (de) 1991-06-13 1992-06-05 Geschützter aminosäurebaustein, herstellung und verwendung

Publications (1)

Publication Number Publication Date
EP0589927A1 true EP0589927A1 (de) 1994-04-06

Family

ID=6433885

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92911418A Withdrawn EP0589927A1 (de) 1991-06-13 1992-06-05 Geschützter aminosäurebaustein, herstellung und verwendung

Country Status (4)

Country Link
EP (1) EP0589927A1 (enrdf_load_stackoverflow)
JP (1) JP3296434B2 (enrdf_load_stackoverflow)
DE (1) DE4119544C1 (enrdf_load_stackoverflow)
WO (1) WO1992022566A1 (enrdf_load_stackoverflow)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117974A (en) * 1991-10-02 2000-09-12 Peptor Limited Libraries of backbone-cyclized peptidomimetics
AU724386B2 (en) * 1994-06-08 2000-09-21 Peptor Ltd Conformationally constrained backbone cyclized peptide analogs
IL109943A (en) * 1994-06-08 2006-08-01 Develogen Israel Ltd Conformationally constrained backbone cyclized peptide analogs
US6407059B1 (en) 1994-06-08 2002-06-18 Peptor Limited Conformationally constrained backbone cyclized peptide analogs
DE4431513A1 (de) * 1994-09-03 1996-03-07 Carsten Goldammer Racemisierungsfreie Herstellung und Verwendung von N-Methoxy- oder -Hydroxy-benzyl-Aminosäurederivaten und -Dipeptiden
US6051554A (en) * 1995-06-07 2000-04-18 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
US5770687A (en) * 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6841533B1 (en) 1995-12-07 2005-01-11 Peptor Limited Conformationally constrained backbone cyclized interleukin-6 antagonists
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
CN103025165B (zh) * 2010-05-05 2016-06-08 普罗林科斯有限责任公司 自大分子共轭物的控释
WO2023219152A1 (ja) * 2022-05-13 2023-11-16 中外製薬株式会社 リチウム塩の析出工程を含む、アミノ酸の塩若しくはペプチド化合物の塩又はこれらの溶媒和物の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH516523A (fr) * 1969-11-25 1971-12-15 Sogespar S A Procédé de préparation des dérivés des acides a-aminés N-disubstitués par benzoylation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9222566A1 *

Also Published As

Publication number Publication date
JPH07501312A (ja) 1995-02-09
WO1992022566A1 (de) 1992-12-23
JP3296434B2 (ja) 2002-07-02
DE4119544C1 (enrdf_load_stackoverflow) 1992-10-15

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