EP0267297A4 - Sialosylcholesterol, procede de preparation et medicament contre les troubles du systeme nerveux. - Google Patents

Sialosylcholesterol, procede de preparation et medicament contre les troubles du systeme nerveux.

Info

Publication number
EP0267297A4
EP0267297A4 EP19870902772 EP87902772A EP0267297A4 EP 0267297 A4 EP0267297 A4 EP 0267297A4 EP 19870902772 EP19870902772 EP 19870902772 EP 87902772 A EP87902772 A EP 87902772A EP 0267297 A4 EP0267297 A4 EP 0267297A4
Authority
EP
European Patent Office
Prior art keywords
sialosylcholesterol
drug
preparation
nervous system
treating diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP19870902772
Other languages
German (de)
English (en)
Other versions
EP0267297A1 (fr
EP0267297B1 (fr
Inventor
Haruo Ogura
Kimio Furuhata
Shingo Sato
Masayoshi Ito
Yoshiyasu Shitori
Yoshitaka Nagai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mect Corp
Original Assignee
Mect Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10822886A external-priority patent/JPH0696535B2/ja
Priority claimed from JP61208380A external-priority patent/JPH07116216B2/ja
Application filed by Mect Corp filed Critical Mect Corp
Priority to AT87902772T priority Critical patent/ATE94558T1/de
Publication of EP0267297A1 publication Critical patent/EP0267297A1/fr
Publication of EP0267297A4 publication Critical patent/EP0267297A4/fr
Application granted granted Critical
Publication of EP0267297B1 publication Critical patent/EP0267297B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
EP87902772A 1986-05-12 1987-05-11 Sialosylcholesterol, procede de preparation et medicament contre les troubles du systeme nerveux Expired - Lifetime EP0267297B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT87902772T ATE94558T1 (de) 1986-05-12 1987-05-11 Sialosylcholesterol, verfahren zu dessen herstellung und arzneimittel zur behandlung von krankheiten des nervensystems.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP108228/86 1986-05-12
JP10822886A JPH0696535B2 (ja) 1986-05-12 1986-05-12 シアロシルコレステロ−ルの神経障害疾患治療剤
JP61208380A JPH07116216B2 (ja) 1986-09-04 1986-09-04 シアロシルコレステロ−ルの製造方法
JP208380/86 1986-09-04

Publications (3)

Publication Number Publication Date
EP0267297A1 EP0267297A1 (fr) 1988-05-18
EP0267297A4 true EP0267297A4 (fr) 1988-08-29
EP0267297B1 EP0267297B1 (fr) 1993-09-15

Family

ID=26448165

Family Applications (1)

Application Number Title Priority Date Filing Date
EP87902772A Expired - Lifetime EP0267297B1 (fr) 1986-05-12 1987-05-11 Sialosylcholesterol, procede de preparation et medicament contre les troubles du systeme nerveux

Country Status (9)

Country Link
US (2) US5023239A (fr)
EP (1) EP0267297B1 (fr)
AU (1) AU594468B2 (fr)
CA (1) CA1324603C (fr)
DE (1) DE3787437T2 (fr)
DK (1) DK170648B1 (fr)
FI (1) FI91071C (fr)
HU (1) HU198216B (fr)
WO (1) WO1987006936A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987006936A1 (fr) * 1986-05-12 1987-11-19 Mect Corporation Sialosylcholesterol, procede de preparation et medicament contre les troubles du systeme nerveux
AU8295591A (en) * 1990-07-17 1992-02-18 European Colour Plc Synthesis of carminic acid and principal intermediates
US5438125A (en) * 1991-03-06 1995-08-01 Nippon Zoki Pharmaceutical Co., Ltd. Sialic acid derivatives
BR9307746A (pt) * 1993-01-08 1995-11-14 Astra Ab Derivados de esteróides especificos para otratamento de cólon e ileo
USRE39300E1 (en) 1993-01-28 2006-09-19 Virginia Commonwealth University Medical College Of Virginia Inhibiting the development of tolerance to and/or dependence on an addictive substance
US5352683A (en) * 1993-03-05 1994-10-04 Virginia Commonwealth University Medical College Of Virginia Method for the treatment of chronic pain
US5783564A (en) * 1993-12-24 1998-07-21 Mitsubishi Chemical Corporation Sialic acid derivatives
DE69616554T2 (de) 1995-06-23 2002-07-11 Mitsubishi Chem Corp Sialinsäure-derivate
WO1999052931A1 (fr) * 1998-04-10 1999-10-21 Mitsubishi Chemical Corporation Dispersion solide contenant un derive d'acide sialique
JP2009523406A (ja) * 2005-11-15 2009-06-25 オクソニカ・インコーポレーテッド 生体剤（ｂｉｏａｇｅｎｔｓ）の検出のためのＳＥＲＳに基づく方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229441A (en) * 1978-12-01 1980-10-21 Merck & Co., Inc. Immunologic adjuvant
JPS5735598A (en) * 1980-08-08 1982-02-26 Nippon Shinyaku Co Ltd Sterylglucoside derivative
JPS60190791A (ja) * 1984-03-09 1985-09-28 Kanto Ishi Pharma Co Ltd シアル酸誘導体およびその製造法
IT1177863B (it) * 1984-07-03 1987-08-26 Fidia Farmaceutici Una miscela gangliosidica come agente terapeutico capare di eliminare il dolore nele neuropatie periferiche
JPS62209094A (ja) * 1986-03-10 1987-09-14 Nippon Zoki Pharmaceut Co Ltd 新規シアル酸誘導体及びその製造方法
WO1987006936A1 (fr) * 1986-05-12 1987-11-19 Mect Corporation Sialosylcholesterol, procede de preparation et medicament contre les troubles du systeme nerveux
JPS6344590A (ja) * 1986-08-12 1988-02-25 Mect Corp シアル酸誘導体の製造方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMISTRY LETTERS, no. 9, 1986 pages 1449-1452, The Chemical Society of Japan, Tokyo, JP; K. OKAMOTO et al.: "A stereospecific synthesis of beta-glycosides of N-acetylneuraminic acid and secondary alcohols" *
See also references of WO8706936A1 *

Also Published As

Publication number Publication date
FI880103A0 (fi) 1988-01-11
EP0267297A1 (fr) 1988-05-18
DK12388A (da) 1988-03-14
CA1324603C (fr) 1993-11-23
HUT46039A (en) 1988-09-28
DE3787437T2 (de) 1994-01-20
US5126330A (en) 1992-06-30
EP0267297B1 (fr) 1993-09-15
AU7394387A (en) 1987-12-01
AU594468B2 (en) 1990-03-08
US5023239A (en) 1991-06-11
WO1987006936A1 (fr) 1987-11-19
DE3787437D1 (de) 1993-10-21
HU198216B (en) 1989-08-28
FI880103A (fi) 1988-01-11
DK12388D0 (da) 1988-01-12
DK170648B1 (da) 1995-11-20
FI91071B (fi) 1994-01-31
FI91071C (fi) 1994-05-10

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