EP0082798B2 - Procédé de désinfection et de nettoyage de lentilles de contact - Google Patents
Procédé de désinfection et de nettoyage de lentilles de contact Download PDFInfo
- Publication number
- EP0082798B2 EP0082798B2 EP82710055A EP82710055A EP0082798B2 EP 0082798 B2 EP0082798 B2 EP 0082798B2 EP 82710055 A EP82710055 A EP 82710055A EP 82710055 A EP82710055 A EP 82710055A EP 0082798 B2 EP0082798 B2 EP 0082798B2
- Authority
- EP
- European Patent Office
- Prior art keywords
- hydrogen peroxide
- solution
- catalase
- contact lenses
- sodium chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/12—Non-macromolecular oxygen-containing compounds, e.g. hydrogen peroxide or ozone
- A61L12/124—Hydrogen peroxide; Peroxy compounds
- A61L12/126—Hydrogen peroxide; Peroxy compounds neutralised with catalase or peroxidase
Definitions
- the invention relates to a method for disinfecting and cleaning contact lenses for the human eye, in which method a hydrogen peroxide solution is first applied to the contact lens during a first period of time and then during a second period of time the adhesive and / or the adhesive adhering to the contact lens this absorbed hydrogen peroxide is split into water and oxygen under the action of a catalyst, and the use of a treatment liquid for the final cleaning of contact lenses which have been subjected to a hygiene treatment in a hydrogen peroxide solution.
- FR-AS-2 231 395 describes a process in which hydrogen peroxide is used, which at the same time has an oxidizing, germicidal, cleaning and odor-eliminating effect.
- the contact lenses are first exposed to a 3 to 30 percent solution of hydrogen peroxide, which can, for example, as described in GB-AS-1 531 035, take place in a small container in which the contact lenses are arranged in a carrier basket are.
- the time period during which the hydrogen peroxide has to act on the contact lenses in order to achieve adequate disinfection and cleaning is approximately 20 minutes.
- the hydrogen peroxide adhering to the contact lenses must then be removed, which in the known method is achieved by placing the contact lenses in a second container in which there is a neutral liquid and a catalyst, in the presence of which the hydrogen peroxide is in accordance with the reaction equation.
- 2 H 2 O 2 ⁇ 2 H 2 O + O 2 is split into water and oxygen.
- the catalyst is a metal-coated solid body.
- the disadvantage of the known process is that the second process step, ie the removal of the hydrogen peroxide by splitting, takes a relatively long time. This takes at least 4 hours. For example, if the user of contact lenses on the previous evening forgets to move the contact lenses from the hydrogen peroxide solution to the solution containing the catalyst, the following morning there is no time to remove the hydrogen peroxide residues from the contact lenses to such an extent that the eyes burn when wearing the contact lenses is avoided.
- the metallic catalyst is added to the hydrogen peroxide solution at the moment in which the hydrogen peroxide solution is brought to act on the contact lenses.
- catalase is mentioned as part of a culture medium and serves to enable the growth of bacteria.
- the invention is based on the object of further developing the method mentioned at the outset in such a way that the time required for the second method step is substantially shortened and at the same time a very high degree of removal of hydrogen peroxide is achieved.
- a method is proposed according to the invention, which is characterized in that after the end of the first period of time the hydrogen peroxide solution surrounding the contact lens is replaced by a saline solution which contains catalase and which corresponds to the concentration of the eye fluid.
- a saline solution which contains catalase is a mixture of at least 100 to 1000, preferably 400 to 600 parts by volume of an approximately 0.8 to 1.0% saline solution and one part by volume of a commercially available highly concentrated catalase solution are used.
- Claims 3 and 4 are directed to the use of a treatment liquid for carrying out the method according to the invention.
- Catalase is an enzyme that is preferably obtained from beef liver and has a crystalline structure.
- the problem with using the organic catalase is that it is not very stable and that it is difficult to store.
- the commercially available, highly concentrated catalase solution mentioned above must be stored at 4 ° C and can only be kept for several months.
- the invention is based on the knowledge that the removal of the hydrogen peroxide residues on the contact lenses in the presence of catalase as a catalyst takes place much faster and more thoroughly than when using the known catalysts that when using the catalase in the isotonic saline solution, the catalase is surprisingly found to be proves to be very long-lasting and not very sensitive to temperature, and that the lenses can be used directly after the treatment without further rinsing. All this makes the method according to the invention extremely suitable for its practical applicability.
- the time span for the second stage of the method is only a few minutes (approximately 5 minutes). In the method according to the invention, it is therefore irrelevant if the user of contact lenses forgets to initiate the second method step in the evening, since it only takes a few minutes to make up for the following morning.
- the very stormy decomposition of the hydrogen peroxide not only significantly shortens the time required; there is also an explosive decomposition of the hydrogen peroxide on the surface of the contact lens, which blows off the contaminants on the surface of the contact lenses that have become brittle during the first process step.
- the removal of the hydrogen peroxide residues in the process according to the invention is so thorough that a subsequent after-treatment (rinsing) of the lenses in a salt solution can be dispensed with.
- the liquid which replaces the hydrogen peroxide solution in the container the above-mentioned liquid consisting of highly concentrated catalase kept in saline. It is also possible to work with two containers, one containing the hydrogen peroxide solution and the other containing the saline solution containing catalase, the concentration of which corresponds to the concentration of the eye fluid, i.e. which is isotonic.
- the concentration at which the catalase in its commercial form of the carrier liquid can vary within wide limits of about 0.1 to 1 volume percent.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agronomy & Crop Science (AREA)
- Inorganic Chemistry (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Eyeglasses (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT82710055T ATE30511T1 (de) | 1981-12-21 | 1982-12-08 | Verfahren zur desinfektion und reinigung von kontaktlinsen. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3150638 | 1981-12-21 | ||
DE3150638 | 1981-12-21 |
Publications (4)
Publication Number | Publication Date |
---|---|
EP0082798A2 EP0082798A2 (fr) | 1983-06-29 |
EP0082798A3 EP0082798A3 (en) | 1983-08-03 |
EP0082798B1 EP0082798B1 (fr) | 1987-11-04 |
EP0082798B2 true EP0082798B2 (fr) | 1991-11-27 |
Family
ID=6149329
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP82710055A Expired - Lifetime EP0082798B2 (fr) | 1981-12-21 | 1982-12-08 | Procédé de désinfection et de nettoyage de lentilles de contact |
Country Status (6)
Country | Link |
---|---|
US (1) | US4585488A (fr) |
EP (1) | EP0082798B2 (fr) |
AT (1) | ATE30511T1 (fr) |
DE (1) | DE3277567D1 (fr) |
HK (1) | HK77990A (fr) |
SG (1) | SG41590G (fr) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4568517A (en) * | 1983-08-25 | 1986-02-04 | Barnes-Hind, Inc. | Disinfection of contact lenses |
AU573247B2 (en) * | 1983-08-25 | 1988-06-02 | Advanced Medical Optics, Inc. | Contact lens disinfection |
GB8332489D0 (en) * | 1983-12-06 | 1984-01-11 | Contactasol Ltd | Contact lenses |
BR8400090A (pt) * | 1984-01-09 | 1984-06-19 | Antonio Carlos Hallais Ribeiro | Processo para a conservacao e limpeza de lentes hidrofilicas |
DE3410400A1 (de) * | 1984-03-21 | 1985-09-26 | Titmus Eurocon Kontaktlinsen GmbH, 8750 Aschaffenburg | Kontaktlinsenpflegesatz und verfahren zur pflege von kontaktlinsen sowie ein reinigungsgeraet hierfuer |
EP0175801B1 (fr) * | 1984-09-24 | 1992-05-20 | Jack Dr. Kessler | Composition bactericide de désinfection pour lentilles de contact et d'autres produits similaires dans un milieu aqueux |
FR2584503B1 (fr) * | 1985-02-07 | 1989-02-24 | Laroche Jean Michel | Procede de sterilisation de lentilles de contact |
GB8515079D0 (en) * | 1985-06-14 | 1985-07-17 | Kellway Pharma | Contact lens cleaning & disinfection |
DE3522282C2 (de) * | 1985-06-21 | 1993-11-25 | Peter Hoefer | Behälter für die Pflege von harten oder weichen Kontaktlinsen |
EP0209071B2 (fr) * | 1985-07-10 | 1998-07-15 | Novartis AG | Kit pour l'entretien des lentilles de contact |
DE3532433A1 (de) * | 1985-09-11 | 1987-03-26 | Iip Inst Fuer Ind Pharmazie Fo | Kontaktlinsenpflegesatz |
DE3524659C2 (de) * | 1985-07-10 | 1999-02-18 | Novartis Ag | Kontaktlinsenpflegesatz |
USRE32672E (en) * | 1985-09-09 | 1988-05-24 | Allergan, Inc. | Method for simultaneously cleaning and disinfecting contact lenses using a mixture of peroxide and proteolytic enzyme |
US4670178A (en) * | 1985-09-09 | 1987-06-02 | Allergan Pharmaceuticals, Inc. | Method for the simultaneous cleaning and disinfecting of contact lenses |
US4757014A (en) * | 1985-11-08 | 1988-07-12 | Minnesota Mining And Manufacturing Company | Immobilization of biologically active protein on a polymeric fibrous support |
US4829001A (en) * | 1985-11-08 | 1989-05-09 | Minnesota Mining And Manufacturing Company | Enzymatic neutralization of hydrogen peroxide |
DE3626082A1 (de) * | 1986-07-31 | 1988-02-11 | Henkel Kgaa | Desinfektions- und reinigungsmittelsystem fuer kontaktlinsen |
US4889689A (en) * | 1986-10-14 | 1989-12-26 | Ciba-Geigy Corporation | Method of disinfecting a soft contact lens with a diethylene triamine penta(methylenephosphonic acid) stabilized hydrogen peroxide solution |
DE3701129A1 (de) * | 1987-01-16 | 1988-07-28 | Henkel Kgaa | Verfahren zur herstellung von desinfizierend wirkenden kontaktlinsen-reinigungsmitteltabletten |
JP2625697B2 (ja) * | 1987-02-06 | 1997-07-02 | 三菱瓦斯化学株式会社 | コンタクトレンズの処理方法 |
US4812173A (en) * | 1987-05-01 | 1989-03-14 | Ciba-Geigy Corporation | Stabilized hydrogen peroxide contact lens disinfecting solution |
DE3806953A1 (de) * | 1988-03-03 | 1989-09-07 | Gerhard Dr Dipl Chem Ludwig | Verfahren zur pflege von kontaktlinsen und vorrichtung hierfuer |
US5059402A (en) * | 1988-08-12 | 1991-10-22 | Seamons Kenneth R | Contact lens disinfection unit |
US4899914A (en) * | 1988-11-04 | 1990-02-13 | Ciba-Geigy Corporation | Method for producing a sterile preservative-free aerosol saline solution |
US4986963A (en) * | 1989-01-24 | 1991-01-22 | Corcoran Richard A | Method of disinfecting contact lenses with peracetic acid |
US4997626A (en) * | 1990-01-05 | 1991-03-05 | Allergan, Inc. | Methods to disinfect contact lenses |
US5279673A (en) * | 1990-01-05 | 1994-01-18 | Allergan, Inc. | Methods to disinfect contact lenses |
US5336434A (en) * | 1989-10-02 | 1994-08-09 | Allergan, Inc. | Methods, compositions and apparatus to disinfect lenses |
US5338480A (en) * | 1989-10-02 | 1994-08-16 | Allegan, Inc. | Compositions and methods to clean contact lenses |
US5246662A (en) * | 1989-10-02 | 1993-09-21 | Allergan, Inc. | Methods for generating chlorine dioxide and compositions for disinfecting |
US5324447A (en) * | 1989-10-02 | 1994-06-28 | Allergan, Inc. | Method and activator compositions to disinfect lenses |
US5078908A (en) * | 1989-10-02 | 1992-01-07 | Allergan, Inc. | Methods for generating chlorine dioxide and compositions for disinfecting |
US5238843A (en) * | 1989-10-27 | 1993-08-24 | Genencor International, Inc. | Method for cleaning a surface on which is bound a glycoside-containing substance |
US5078798A (en) * | 1989-12-28 | 1992-01-07 | Ciba-Geigy Corporation | Buoyancy mediated control of catalytic reaction |
US5320806A (en) * | 1990-01-05 | 1994-06-14 | Allegan, Inc. | Methods to disinfect contact lenses |
ATE173639T1 (de) * | 1990-02-27 | 1998-12-15 | Allergan Inc | Wasserstoffperoxid zersetzende zusammensetzungen und verfahren zur herstellung und verwendung derselben |
WO1992004921A1 (fr) * | 1990-09-25 | 1992-04-02 | Allergan, Inc. | Appareil et procede de desinfection d'une lentille de contact et de detection de la presence d'un desinfectant oxydant |
US5129999A (en) * | 1990-10-04 | 1992-07-14 | Allergan, Inc. | Lens disinfector and method |
US5145644A (en) * | 1990-12-20 | 1992-09-08 | Allergan, Inc. | Hydrogen peroxide destroying compositions and methods of making and using same |
US5556480A (en) * | 1991-05-07 | 1996-09-17 | Dirygesa, S.L. | Procedure for disinfecting and cleaning contact lenses |
ES2041561B1 (es) * | 1991-05-07 | 1994-06-01 | Dirygesa Sl | Procedimiento para desinfectar y limpiar lentes de contacto. |
US5523012A (en) * | 1991-07-19 | 1996-06-04 | Ciba-Geigy Corporation | Hydrogen peroxide disinfection solutions |
NZ243749A (en) * | 1991-08-30 | 1994-11-25 | Allergan Inc | Composition for neutralising and indicating the absence of peroxide comprising a neutralising compound and vitamin b-12 |
US5270002A (en) * | 1991-10-03 | 1993-12-14 | Allergan, Inc. | Apparatus and method useful in disinfecting contact lenses |
NL9101986A (nl) * | 1991-11-28 | 1993-06-16 | Jon Holding B V | Werkwijze voor het bereiden van waterige vloeistof voor het reinigen van contactlenzen. |
US5197636A (en) * | 1992-02-03 | 1993-03-30 | Allergan, Inc. | Fast activation chlorine dioxide delivery apparatus |
AU676268B2 (en) * | 1992-12-28 | 1997-03-06 | Bausch & Lomb Incorporated | Controlled release composition for active substances into anaqueous medium |
US5364601A (en) * | 1992-12-30 | 1994-11-15 | Bausch & Lomb Incorporated | Treating of contact lenses with compositions comprising PVP-H202 |
AU677638B2 (en) | 1993-01-26 | 1997-05-01 | Allergan, Inc. | Compositions and methods to disinfect contact lenses |
US5362647A (en) * | 1993-02-12 | 1994-11-08 | Allergan, Inc. | Compositions and methods for destroying hydrogen peroxide |
US5736165A (en) * | 1993-05-25 | 1998-04-07 | Allergan | In-the-eye use of chlorine dioxide-containing compositions |
US5648074A (en) * | 1993-05-25 | 1997-07-15 | Allergan | Compositions and methods for disinfecting contact lenses and reducing proteinaceous deposit formation |
US5447650A (en) * | 1993-10-06 | 1995-09-05 | Allergan, Inc. | Composition for preventing the accumulation of inorganic deposits on contact lenses |
US6024954A (en) * | 1994-12-12 | 2000-02-15 | Allergan | Compositions and methods for disinfecting contact lenses and preserving contact lens care products |
US6022721A (en) * | 1997-01-03 | 2000-02-08 | Development Center For Biotechnology | Catalase, the gene thereof and composition comprising the same, and process for preparing catalase using genetic engineering technology |
US6022732A (en) * | 1997-04-09 | 2000-02-08 | Allergan | Hydrogen peroxide destroying compositions and methods of using same |
US20070228085A1 (en) * | 2006-03-31 | 2007-10-04 | Szu-Min Lin | Dispenser for delivering foam and mist |
US20070231196A1 (en) * | 2006-03-31 | 2007-10-04 | Szu-Min Lin | Foam pretreatment for medical instruments |
US20070231200A1 (en) * | 2006-03-31 | 2007-10-04 | Szu-Min Lin | Hydrogen peroxide foam treatment |
RU2574010C2 (ru) * | 2009-11-17 | 2016-01-27 | Новартис Аг | Раствор пероксида и набор для дезинфекции контактных линз |
RU2012142507A (ru) * | 2010-03-08 | 2014-04-20 | Новартис Аг | Система для дезинфекции на основе активного кислорода и ее применение |
WO2012072777A1 (fr) * | 2010-12-01 | 2012-06-07 | B.R.A.I.N. Biotechnology Research And Information Network Ag | Nouvelles catalases |
EP3125958A1 (fr) | 2014-04-03 | 2017-02-08 | Novartis AG | Système pour la désinfection de lentilles de contact |
CA2939880C (fr) | 2014-04-03 | 2018-05-22 | Novartis Ag | Systeme electrochimique pour desinfecter et nettoyer des lentilles de contact |
US11717591B2 (en) | 2018-11-29 | 2023-08-08 | Better Vision Solutions LLC | Methods for disinfecting contact lenses with a manganese-coated disc, and related contact lens treatment systems |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL93177C (fr) * | 1955-02-04 | |||
US3240709A (en) * | 1962-05-16 | 1966-03-15 | Burton Parsons Chemicals Inc | Method of cleansing contact lenses |
US3282702A (en) * | 1963-07-16 | 1966-11-01 | Union Carbide Corp | Process for removing hydrogen peroxide from liquids |
FR1550186A (fr) * | 1967-08-31 | 1968-12-20 | ||
BE759530A (fr) * | 1969-11-28 | 1971-04-30 | Griffin Lab Inc | Lentille de contact et son procede de fabrication |
US3912451A (en) * | 1973-06-04 | 1975-10-14 | Warner Lambert Co | Method for removing hydrogen peroxide from soft contact lenses |
JPS5036685A (fr) * | 1973-08-08 | 1975-04-05 | ||
IL47468A (en) * | 1975-06-12 | 1979-05-31 | Rehovot Res Prod | Process for the cross-linking of proteins using water soluble cross-linking agents |
US4013410A (en) * | 1975-06-23 | 1977-03-22 | Ryder International Corporation | Contact lens sterilization process and apparatus |
GB1531035A (en) * | 1976-08-04 | 1978-11-01 | Ryder Int Corp | Contact lens sterilization process and apparatus |
JPS5324093A (en) * | 1976-08-12 | 1978-03-06 | Amano Pharma Co Ltd | Production of stabilized liquid catalase |
US4096870A (en) * | 1977-06-09 | 1978-06-27 | Burton, Parsons And Company, Inc. | Method for cleaning soft hydrophilic gel contact lenses |
JPS5749453A (en) * | 1980-09-05 | 1982-03-23 | Jujo Paper Co Ltd | Method of removing hydrogen peroxide from food instrument material |
US4473550A (en) * | 1981-01-16 | 1984-09-25 | Rosenbaum Robert S | Bactericidal compositions and methods |
US4414127A (en) * | 1981-07-06 | 1983-11-08 | Syntex (U.S.A.) Inc. | Contact lens cleaning solutions |
US4521375A (en) * | 1982-11-23 | 1985-06-04 | Coopervision, Inc. | Sterilizing treatment with hydrogen peroxide and neutralization of residual amounts thereof |
-
1982
- 1982-12-08 EP EP82710055A patent/EP0082798B2/fr not_active Expired - Lifetime
- 1982-12-08 DE DE8282710055T patent/DE3277567D1/de not_active Expired
- 1982-12-08 AT AT82710055T patent/ATE30511T1/de not_active IP Right Cessation
- 1982-12-20 US US06/451,562 patent/US4585488A/en not_active Expired - Lifetime
-
1990
- 1990-06-13 SG SG415/90A patent/SG41590G/en unknown
- 1990-09-27 HK HK779/90A patent/HK77990A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4585488A (en) | 1986-04-29 |
DE3277567D1 (en) | 1987-12-10 |
EP0082798A3 (en) | 1983-08-03 |
EP0082798B1 (fr) | 1987-11-04 |
ATE30511T1 (de) | 1987-11-15 |
EP0082798A2 (fr) | 1983-06-29 |
HK77990A (en) | 1990-10-05 |
SG41590G (en) | 1991-02-14 |
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