EG24177A - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- EG24177A EG24177A EG132598A EG132598A EG24177A EG 24177 A EG24177 A EG 24177A EG 132598 A EG132598 A EG 132598A EG 132598 A EG132598 A EG 132598A EG 24177 A EG24177 A EG 24177A
- Authority
- EG
- Egypt
- Prior art keywords
- novel compounds
- novel
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C271/36—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9722817.5A GB9722817D0 (en) | 1997-10-29 | 1997-10-29 | Novel compounds |
GBGB9813689.8A GB9813689D0 (en) | 1998-06-25 | 1998-06-25 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
EG24177A true EG24177A (en) | 2008-09-28 |
Family
ID=26312507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EG132598A EG24177A (en) | 1997-10-29 | 1998-10-29 | Novel compounds |
Country Status (36)
Country | Link |
---|---|
US (3) | US6281226B1 (fr) |
EP (3) | EP1930330B1 (fr) |
JP (2) | JP4227729B2 (fr) |
KR (1) | KR100538721B1 (fr) |
CN (1) | CN1205211C (fr) |
AR (1) | AR015987A1 (fr) |
AT (2) | ATE525373T1 (fr) |
AU (1) | AU742167C (fr) |
BR (1) | BR9814747B1 (fr) |
CA (1) | CA2307551C (fr) |
CO (1) | CO5021129A1 (fr) |
CY (2) | CY2007028I2 (fr) |
CZ (1) | CZ298543B6 (fr) |
DE (2) | DE69826704T3 (fr) |
DK (2) | DK1028961T5 (fr) |
DZ (1) | DZ2634A1 (fr) |
EG (1) | EG24177A (fr) |
ES (2) | ES2229538T7 (fr) |
FR (1) | FR07C0057I2 (fr) |
HK (1) | HK1031376A1 (fr) |
HU (2) | HU229792B1 (fr) |
IL (2) | IL135811A0 (fr) |
LU (1) | LU91372I2 (fr) |
MY (1) | MY130665A (fr) |
NL (1) | NL300304I2 (fr) |
NO (3) | NO327392B1 (fr) |
NZ (1) | NZ504203A (fr) |
PE (1) | PE123299A1 (fr) |
PL (2) | PL197672B1 (fr) |
PT (2) | PT1930330E (fr) |
SI (2) | SI1930330T1 (fr) |
TR (1) | TR200001203T2 (fr) |
TW (1) | TWI232861B (fr) |
UY (1) | UY25225A1 (fr) |
WO (1) | WO1999021855A1 (fr) |
ZA (1) | ZA989767B (fr) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UY25225A1 (es) * | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | Derivados de pleuromutilina utiles como agentes antimicrobianos |
WO2000027790A1 (fr) * | 1998-11-11 | 2000-05-18 | Smithkline Beecham P.L.C. | Composes a base de mutiline |
GB9912657D0 (en) * | 1999-06-01 | 1999-07-28 | Smithkline Beecham Plc | Novel compounds |
GB9918037D0 (en) | 1999-07-30 | 1999-09-29 | Biochemie Gmbh | Organic compounds |
GB9919839D0 (en) * | 1999-08-20 | 1999-10-27 | Smithkline Beecham Plc | Novel compounds |
HUP0300370A3 (en) | 2000-04-04 | 2005-07-28 | Smithkline Beecham Plc | 2-hydroxy-mutilin carbamate derivatives of antibacterial effect process for preparation and pharmaceutical compositions containing them |
GB0017031D0 (en) | 2000-07-11 | 2000-08-30 | Biochemie Gmbh | Antimicrobials |
GB0017073D0 (en) * | 2000-07-11 | 2000-08-30 | Univ London | Microorganism |
PE20020676A1 (es) * | 2000-09-13 | 2002-08-27 | Biochemie Gmbh | Compuestos de mutilina como antibacterianos |
GB0024811D0 (en) * | 2000-10-10 | 2000-11-22 | Smithkline Beecham Plc | Novel compounds |
GB0027705D0 (en) | 2000-11-11 | 2000-12-27 | S P A | Novel compounds |
FR2835186B1 (fr) * | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
GB0207495D0 (en) * | 2002-03-28 | 2002-05-08 | Biochemie Gmbh | Organic compounds |
ES2295657T3 (es) * | 2002-07-24 | 2008-04-16 | Nabriva Therapeutics Forschungs Gmbh | Derivados de pleuromutilina como antimicrobianos. |
GB0218578D0 (en) * | 2002-08-09 | 2002-09-18 | Glaxo Group Ltd | Novel method |
GB0308114D0 (en) * | 2003-04-08 | 2003-05-14 | Glaxo Group Ltd | Novel compounds |
JP5460947B2 (ja) * | 2003-09-03 | 2014-04-02 | グラクソ グループ リミテッド | 新規調製方法、塩、組成物及び使用 |
EP1747219A4 (fr) * | 2004-05-13 | 2010-05-26 | Glaxo Group Ltd | Domaine de l'invention antagonistes récepteurs d'acétyle choline muscarinique |
GB0504314D0 (en) * | 2005-03-02 | 2005-04-06 | Glaxo Group Ltd | Novel polymorph |
WO2006104667A2 (fr) * | 2005-03-10 | 2006-10-05 | Smithkline Beecham Corporation | Nouveau procede |
GB0513058D0 (en) * | 2005-06-27 | 2005-08-03 | Sandoz Ag | Organic compounds |
EP2298733B1 (fr) * | 2005-06-27 | 2016-05-25 | Nabriva Therapeutics AG | Dérivés de la pleuromutiline contenant un groupe hydroxyamino- ou acyloxyaminocycloalkyle |
WO2007037518A1 (fr) * | 2005-09-29 | 2007-04-05 | Dainippon Sumitomo Pharma Co., Ltd. | Derive de mutiline et composition pharmaceutique la contenant |
WO2007079173A2 (fr) * | 2005-12-30 | 2007-07-12 | Emergent Biosolutions Inc. | Nouveaux dérivés de 2-hétéroaryloxyphénol au titre d'agents antibactériens |
JP5293192B2 (ja) | 2007-02-09 | 2013-09-18 | アステラス製薬株式会社 | アザ架橋環化合物 |
WO2008117796A1 (fr) * | 2007-03-28 | 2008-10-02 | Dainippon Sumitomo Pharma Co., Ltd. | Nouveaux dérivés de mutiline |
US8222407B2 (en) | 2007-05-24 | 2012-07-17 | Kyorin Pharmaceutical Co., Ltd. | Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position |
US20090076071A1 (en) * | 2007-09-13 | 2009-03-19 | Protia, Llc | Deuterium-enriched retapamulin |
WO2009070307A1 (fr) * | 2007-11-26 | 2009-06-04 | Teva Pharmaceutical Industries Ltd. | Rétapamuline amorphe et ses procédés de préparation |
WO2009075776A1 (fr) * | 2007-12-05 | 2009-06-18 | Teva Pharmaceutical Industries Ltd. | Procédé pour préparer de la rétapamuline et ses intermédiaires |
US8278313B2 (en) | 2008-03-11 | 2012-10-02 | Abbott Laboratories | Macrocyclic spiro pyrimidine derivatives |
US8436005B2 (en) | 2008-04-03 | 2013-05-07 | Abbott Laboratories | Macrocyclic pyrimidine derivatives |
WO2010056855A1 (fr) * | 2008-11-13 | 2010-05-20 | Teva Pharmaceutical Industries Ltd. | Préparation de rétapamuline par l'intermédiaire de son précurseur pleuromutiline-thiol |
US20120107854A1 (en) * | 2009-03-03 | 2012-05-03 | National Institute Of Radiological Sciences | Reagent for measurement of cholinesterase activity |
KR20120104512A (ko) | 2009-07-14 | 2012-09-21 | 알바니 몰레큘라 리써치, 인크. | 5-ht3 수용체 조절체, 이의 제조 방법, 및 그의 용도 |
CN102344397B (zh) * | 2011-08-23 | 2013-09-04 | 浙江升华拜克生物股份有限公司 | 一种伐奈莫林盐酸盐的提纯方法 |
CN103626693B (zh) * | 2012-08-28 | 2016-09-14 | 中国科学院上海药物研究所 | 一类截短侧耳素衍生物、其药物组合物及其合成方法与用途 |
CN103709093B (zh) * | 2012-09-28 | 2016-06-08 | 山东亨利医药科技有限责任公司 | 含有并环的截短侧耳素类抗生素 |
WO2016014581A1 (fr) | 2014-07-21 | 2016-01-28 | Endochoice, Inc. | Systèmes d'endoscope à foyers multiples et à caméra multiples |
US10874679B2 (en) | 2016-03-02 | 2020-12-29 | Bill & Melinda Gates Foundation | Boron-containing small molecules |
EP3423159A4 (fr) * | 2016-03-02 | 2019-11-06 | Anacor Pharmaceuticals, Inc. | Petites molécules contenant du bore |
US10611780B2 (en) | 2016-03-02 | 2020-04-07 | Bill And Melinda Gates Foundation | Boron-containing small molecules |
CN106496085B (zh) * | 2016-09-21 | 2018-01-26 | 盐城市舜宝化工有限公司 | 合成盐酸沃尼妙林的中间体化合物以及盐酸沃尼妙林的制备方法 |
TWI762573B (zh) | 2017-02-10 | 2022-05-01 | 奧地利商納畢瓦治療有限責任公司 | 截短側耳素之純化 |
CN111574395B (zh) * | 2020-06-18 | 2021-07-02 | 华南农业大学 | 一种具有酰胺侧链的截短侧耳素衍生物及制备与应用 |
AT523646B1 (de) | 2020-07-21 | 2021-10-15 | Gerd Dr Ascher | Pharmazeutische Verbindungen, ihre Anwendung alleine oder in Kombination, zur Prophylaxe und lokalen Initial-Therapie bei bakteriellen und viralen Infektionen, insbesondere Coronaviren |
US11155514B1 (en) * | 2020-12-19 | 2021-10-26 | Shaanxi University Of Science And Technology | Pleuromulin acitretin ester with antibacterial activity and a method of preparing the same |
US11332430B1 (en) * | 2021-01-25 | 2022-05-17 | Xi'an Taikomed Pharmaceutical Technology Co., Ltd. | Pleuromulin lauric acid ester with antibacterial activity and a method of preparing the same |
CN112919463B (zh) * | 2021-04-09 | 2021-10-26 | 南京理工大学 | 一种利用泰妙菌素废盐制备的活性炭及其制备方法 |
CN113121355B (zh) * | 2021-04-13 | 2023-05-09 | 西安康诺化工有限公司 | 一种截短侧耳素大黄酸酯及其制备方法和应用 |
CN114736194A (zh) * | 2022-03-29 | 2022-07-12 | 中牧实业股份有限公司 | 一种具有抗病原微生物活性的含吡啶季铵盐侧链的截短侧耳素衍生物及其制备方法与应用 |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4060542A (en) | 1969-07-25 | 1977-11-29 | Biochemie Gesellschaft M.B.H. | 14-Desoxy-14 thiocyanato-acetoxy-mutilin |
US4032530A (en) | 1971-10-05 | 1977-06-28 | Sandoz Ltd. | Certain pleuromutilins |
US4208326A (en) | 1971-10-05 | 1980-06-17 | Sandoz Ltd. | Pleuromutilin esters |
BE789629A (fr) * | 1971-10-05 | 1973-04-03 | Sandoz Sa | Nouveaux derives de la pleuromutiline, leur preparation et leurapplication en therapeutique |
CH575375A5 (fr) | 1972-05-25 | 1976-05-14 | Sandoz Ag | |
US3919290A (en) | 1972-10-03 | 1975-11-11 | Sandoz Ltd | Substituted 14-desoxy-mutilins |
CH593912A5 (en) | 1972-07-07 | 1977-12-30 | Sandoz Ag | Pleuromutilin derivs. - prepd. by acylating derivs. contg. a (4)-hydroxyalkyl-(1)-piperazinyl gp. |
DE2404046C3 (de) | 1974-01-29 | 1984-07-26 | Henkel KGaA, 4000 Düsseldorf | Verwendung von Carboxyl- bzw. Carboxylat- und Hydroxylgruppen aufweisenden Polymeren als Hautfeuchthaltemittel |
US3987194A (en) | 1975-05-12 | 1976-10-19 | E. R. Squibb & Sons, Inc. | Use of pleuromutilin derivatives for the treatment of swine dysentery |
CH619450A5 (fr) | 1976-01-15 | 1980-09-30 | Sandoz Ag | |
US4130709A (en) | 1977-12-08 | 1978-12-19 | Eli Lilly And Company | Pleuromutilin glycoside derivatives |
GB2025930B (en) * | 1978-06-01 | 1983-02-09 | Sandoz Ltd | Process for the production of pleuromutilin derivatives |
DE2966635D1 (en) * | 1979-01-12 | 1984-03-08 | Sandoz Ag | New pleuromutilin derivatives, their production and pharmaceutical compositions containing them |
JPS5594359A (en) * | 1979-01-12 | 1980-07-17 | Sandoz Ag | Novel pleuromutilin derivatives*their manufacture and use |
FR2502951B1 (fr) | 1981-04-06 | 1985-12-06 | Sandoz Sa | Compositions pharmaceutiques topiques sous forme d'une micro-emulsion |
DE3560511D1 (en) * | 1984-02-17 | 1987-10-01 | Sandoz Ag | Pleuromutilin derivatives, process for their preparation and their use |
DE3405632A1 (de) * | 1984-02-17 | 1985-08-22 | Sandoz-Patent-GmbH, 7850 Lörrach | Neue pleuromutilinderivate, verfahren zu ihrer herstellung und ihre verwendung |
AT400674B (de) | 1991-07-24 | 1996-02-26 | Biochemie Gmbh | Pharmazeutische pleuromutilin-zubereitung |
GB9201751D0 (en) | 1992-01-28 | 1992-03-11 | Smithkline Beecham Plc | Compounds |
AT397654B (de) | 1992-05-04 | 1994-06-27 | Biochemie Gmbh | Neue pleuromutilinderivate, ihre verwendung und verfahren zu ihrer herstellung |
EE9700141A (et) | 1994-12-23 | 1997-12-15 | Dr. Karl Thomae Gmbh | Piperasiinderivaadid, neid sisaldavad ravimid, nende kasutamine ja valmistamise meetod |
TR199801282T2 (xx) * | 1996-01-03 | 1998-12-21 | Smithkline Beecham P.L.C. | Mutilin'in karbamoiloksi t�revleri ve antibakteriyel olarak kullan�m�. |
HUP0001741A3 (en) | 1996-08-02 | 2000-11-28 | Smithkline Beecham Plc | Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use, process for preparing them, pharmaceuticals contg. them and their use |
AU724070B2 (en) | 1996-10-01 | 2000-09-14 | Smithkline Beecham Corporation | Use of mupirocin for the manufacture of a medicament for the treatment of bacterial infections associated with colonisation of the nasopharynx by pathogenic organisms |
UY25225A1 (es) * | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | Derivados de pleuromutilina utiles como agentes antimicrobianos |
JP5460947B2 (ja) | 2003-09-03 | 2014-04-02 | グラクソ グループ リミテッド | 新規調製方法、塩、組成物及び使用 |
GB0504314D0 (en) | 2005-03-02 | 2005-04-06 | Glaxo Group Ltd | Novel polymorph |
-
1996
- 1996-05-07 UY UY25225A patent/UY25225A1/es not_active IP Right Cessation
-
1998
- 1998-10-27 DK DK98950202T patent/DK1028961T5/da active
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- 1998-10-27 US US09/530,446 patent/US6281226B1/en not_active Ceased
- 1998-10-27 AU AU96361/98A patent/AU742167C/en not_active Expired
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- 1998-10-27 AT AT08152170T patent/ATE525373T1/de active
- 1998-10-27 JP JP2000517965A patent/JP4227729B2/ja not_active Expired - Lifetime
- 1998-10-27 WO PCT/GB1998/003211 patent/WO1999021855A1/fr active IP Right Grant
- 1998-10-27 CN CNB988127318A patent/CN1205211C/zh not_active Expired - Lifetime
- 1998-10-27 EP EP08152170A patent/EP1930330B1/fr not_active Expired - Lifetime
- 1998-10-27 PL PL340254A patent/PL191927B1/pl unknown
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- 1998-10-27 HU HU0004040A patent/HU229792B1/hu active Protection Beyond IP Right Term
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- 1998-10-27 CA CA002307551A patent/CA2307551C/fr not_active Expired - Lifetime
- 1998-10-27 DK DK08152170.0T patent/DK1930330T3/da active
- 1998-10-27 ES ES98950202T patent/ES2229538T7/es active Active
- 1998-10-27 TR TR2000/01203T patent/TR200001203T2/xx unknown
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- 1998-10-27 KR KR10-2000-7004707A patent/KR100538721B1/ko not_active IP Right Cessation
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- 1998-10-27 AR ARP980105377A patent/AR015987A1/es active IP Right Grant
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- 1998-10-27 DE DE122007000076C patent/DE122007000076I2/de active Active
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- 1998-10-27 EP EP04076485A patent/EP1452534A1/fr not_active Withdrawn
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- 1998-10-28 DZ DZ980244A patent/DZ2634A1/fr active
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- 1998-10-29 PE PE1998001018A patent/PE123299A1/es not_active Application Discontinuation
- 1998-10-29 EG EG132598A patent/EG24177A/xx active
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2000
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2001
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2007
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- 2007-11-09 FR FR07C0057C patent/FR07C0057I2/fr active Active
- 2007-11-12 CY CY200700028C patent/CY2007028I2/el unknown
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2008
- 2008-08-25 JP JP2008215667A patent/JP2009040789A/ja active Pending
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2009
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2011
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2014
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