EG15376A - Process for preparing n-(1-allyl-2 pyrrolidinyl-methyl)2-methoxy 4-amino-5-methylsulfamoyl benzamide,and its use as a medicament - Google Patents

Process for preparing n-(1-allyl-2 pyrrolidinyl-methyl)2-methoxy 4-amino-5-methylsulfamoyl benzamide,and its use as a medicament

Info

Publication number
EG15376A
EG15376A EG434/81A EG43481A EG15376A EG 15376 A EG15376 A EG 15376A EG 434/81 A EG434/81 A EG 434/81A EG 43481 A EG43481 A EG 43481A EG 15376 A EG15376 A EG 15376A
Authority
EG
Egypt
Prior art keywords
pyrrolidinyl
allyl
medicament
methoxy
amino
Prior art date
Application number
EG434/81A
Other languages
English (en)
Inventor
Perrot Jacques
Thominet Michel
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Application granted granted Critical
Publication of EG15376A publication Critical patent/EG15376A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
EG434/81A 1980-08-28 1981-07-28 Process for preparing n-(1-allyl-2 pyrrolidinyl-methyl)2-methoxy 4-amino-5-methylsulfamoyl benzamide,and its use as a medicament EG15376A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8018635A FR2489327B1 (fr) 1980-08-28 1980-08-28 N (1 allyl 2 pyrrolidinyl methyl) 2 methoxy 4 amino 5 methylsulfa moyl benzamide, son procede de preparation et son application comme medicament

Publications (1)

Publication Number Publication Date
EG15376A true EG15376A (en) 1986-12-30

Family

ID=9245444

Family Applications (1)

Application Number Title Priority Date Filing Date
EG434/81A EG15376A (en) 1980-08-28 1981-07-28 Process for preparing n-(1-allyl-2 pyrrolidinyl-methyl)2-methoxy 4-amino-5-methylsulfamoyl benzamide,and its use as a medicament

Country Status (41)

Country Link
US (2) US4405636A (da)
EP (1) EP0047207B1 (da)
JP (1) JPS5775969A (da)
KR (1) KR840002063B1 (da)
AR (1) AR226737A1 (da)
AT (1) ATE11911T1 (da)
AU (1) AU549396B2 (da)
BE (1) BE890085A (da)
BG (1) BG36931A3 (da)
CA (1) CA1168250A (da)
CH (1) CH648299A5 (da)
CS (1) CS223895B2 (da)
DD (1) DD202011A5 (da)
DE (2) DE3133768A1 (da)
DK (1) DK157845C (da)
EG (1) EG15376A (da)
ES (1) ES8301466A1 (da)
FI (1) FI73207C (da)
FR (1) FR2489327B1 (da)
GB (1) GB2083033B (da)
GR (1) GR74560B (da)
HK (1) HK55989A (da)
HU (1) HU183555B (da)
IE (1) IE51357B1 (da)
IL (1) IL63217A (da)
IN (1) IN155495B (da)
IS (1) IS1213B6 (da)
IT (1) IT1171490B (da)
JO (1) JO1120B1 (da)
LU (1) LU83583A1 (da)
MA (1) MA19218A1 (da)
MX (1) MX6707E (da)
NO (1) NO155097C (da)
OA (1) OA06877A (da)
PH (1) PH19211A (da)
PL (1) PL135397B1 (da)
PT (1) PT73509B (da)
SU (1) SU1148559A3 (da)
YU (1) YU42581B (da)
ZA (1) ZA814575B (da)
ZW (1) ZW17581A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8317597D0 (en) * 1983-06-29 1983-08-03 Beecham Group Plc Pharmaceutical compounds
FR2550447B1 (fr) * 1983-08-10 1986-01-17 Ile De France Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire
FR2584605B1 (fr) * 1985-07-15 1988-06-17 Ile De France Application du n-(1-allyl-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide dans le traitement de la maladie de parkinson
US7544676B2 (en) * 2005-11-10 2009-06-09 Adolor Corporation Sulfamoyl benzamides and methods of their use
CN101628886B (zh) * 2009-08-25 2012-12-12 北京紫萌同达科技有限公司 一种2-甲氧基-4-氨基-5-乙砜基苯甲酸的合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1525M (fr) * 1961-07-25 1962-11-16 Ile De France Médicaments antiémétiques nouveaux.
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR5916M (da) * 1966-01-21 1968-05-06
US3766178A (en) * 1967-04-03 1973-10-16 Ile De France Substituted 2-arylalkyloxy benzamides
GB1364231A (en) 1968-12-23 1974-08-21 Robins Co Inc A H N-/1-substituted-3-pyrrolidinyl/benzamides and thiobenzamides
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
FR2244760B1 (da) * 1973-09-25 1980-06-27 Ile De France
CH605793A5 (da) * 1974-03-05 1978-10-13 Ile De France
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
US4197243A (en) * 1975-04-02 1980-04-08 Yamanouchi Pharmaceutical Co., Ltd. N-1-Benzyl-3-pyrrolidinyl-4-dimethylamino benzamide derivatives
US4186135A (en) * 1976-08-04 1980-01-29 Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation
FR2438650A1 (fr) * 1978-10-11 1980-05-09 Ile De France N-(1-methyl 2-pyrrolidinyl methyl) 2,3-dimethoxy 5-methylsulfamoyl benzamide et ses derives, leurs methodes de preparation et leur application dans le traitement des troubles du bas appareil urinaire
US4210660A (en) * 1978-12-20 1980-07-01 Yamanouchi Pharmaceutical Co., Ltd. Benzamide derivatives
JPS55130957A (en) * 1979-03-30 1980-10-11 Kyowa Hakko Kogyo Co Ltd Production of benzamide derivative

Also Published As

Publication number Publication date
JO1120B1 (en) 1982-07-10
ZW17581A1 (en) 1981-10-21
FI73207C (fi) 1987-09-10
LU83583A1 (fr) 1981-12-01
BE890085A (fr) 1982-02-26
DE3133768A1 (de) 1982-06-16
GR74560B (da) 1984-06-29
CH648299A5 (fr) 1985-03-15
GB2083033B (en) 1984-02-01
EP0047207B1 (fr) 1985-02-20
DK383081A (da) 1982-03-01
DK157845C (da) 1990-07-23
YU201081A (en) 1983-10-31
KR830006201A (ko) 1983-09-20
SU1148559A3 (ru) 1985-03-30
EP0047207A1 (fr) 1982-03-10
IE51357B1 (en) 1986-12-10
MX6707E (es) 1985-10-23
JPS5775969A (en) 1982-05-12
US4405636A (en) 1983-09-20
IT1171490B (it) 1987-06-10
GB2083033A (en) 1982-03-17
ES503805A0 (es) 1982-12-01
DK157845B (da) 1990-02-26
NO155097C (no) 1987-02-11
AU549396B2 (en) 1986-01-23
IL63217A (en) 1985-03-31
FI812506L (fi) 1982-03-01
ZA814575B (en) 1982-07-28
AR226737A1 (es) 1982-08-13
PH19211A (en) 1986-02-04
CS223895B2 (en) 1983-11-25
NO812937L (no) 1982-03-01
IE811449L (en) 1982-02-28
DD202011A5 (de) 1983-08-24
AU7464281A (en) 1982-03-04
OA06877A (fr) 1983-04-30
IS1213B6 (is) 1986-04-02
PT73509A (fr) 1981-09-01
NO155097B (no) 1986-11-03
IS2654A7 (is) 1981-09-11
IN155495B (da) 1985-02-09
MA19218A1 (fr) 1982-04-01
PL135397B1 (en) 1985-10-31
IT8149179A0 (it) 1981-08-26
CA1168250A (fr) 1984-05-29
ATE11911T1 (de) 1985-03-15
ES8301466A1 (es) 1982-12-01
PT73509B (fr) 1982-10-28
BG36931A3 (en) 1985-02-15
HK55989A (en) 1989-07-21
KR840002063B1 (ko) 1984-11-09
HU183555B (en) 1984-05-28
US4550179A (en) 1985-10-29
IL63217A0 (en) 1981-10-30
YU42581B (en) 1988-10-31
JPH0233027B2 (da) 1990-07-25
FI73207B (fi) 1987-05-29
FR2489327A1 (fr) 1982-03-05
PL232686A1 (da) 1982-03-01
DE3169052D1 (en) 1985-03-28
FR2489327B1 (fr) 1984-05-18

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