EG12387A - Process for preparing of piperazinyl pyrazines - Google Patents

Process for preparing of piperazinyl pyrazines

Info

Publication number
EG12387A
EG12387A EG76205A EG20576A EG12387A EG 12387 A EG12387 A EG 12387A EG 76205 A EG76205 A EG 76205A EG 20576 A EG20576 A EG 20576A EG 12387 A EG12387 A EG 12387A
Authority
EG
Egypt
Prior art keywords
preparing
pyrazines
piperazinyl
piperazinyl pyrazines
Prior art date
Application number
EG76205A
Other languages
English (en)
Inventor
W Lumma
W Saari
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of EG12387A publication Critical patent/EG12387A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EG76205A 1975-04-21 1976-04-07 Process for preparing of piperazinyl pyrazines EG12387A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57005275A 1975-04-21 1975-04-21

Publications (1)

Publication Number Publication Date
EG12387A true EG12387A (en) 1978-12-31

Family

ID=24277994

Family Applications (1)

Application Number Title Priority Date Filing Date
EG76205A EG12387A (en) 1975-04-21 1976-04-07 Process for preparing of piperazinyl pyrazines

Country Status (36)

Country Link
JP (1) JPS51136688A (cs)
AR (1) AR210349A1 (cs)
AT (1) AT353795B (cs)
AU (1) AU496854B2 (cs)
BE (1) BE840904A (cs)
BG (1) BG34185A3 (cs)
CA (1) CA1059128A (cs)
CH (1) CH619462A5 (cs)
CS (1) CS195726B2 (cs)
CY (1) CY1090A (cs)
DD (1) DD124599A5 (cs)
DE (1) DE2617205C3 (cs)
DK (1) DK143899C (cs)
EG (1) EG12387A (cs)
ES (4) ES447150A1 (cs)
FI (1) FI62666C (cs)
FR (1) FR2308367A1 (cs)
GB (1) GB1492528A (cs)
GR (1) GR59900B (cs)
HK (1) HK60380A (cs)
HU (1) HU172684B (cs)
IE (1) IE42979B1 (cs)
IL (1) IL49391A (cs)
KE (1) KE3088A (cs)
LU (1) LU74795A1 (cs)
MY (1) MY8100225A (cs)
NL (1) NL167692C (cs)
NO (1) NO146599C (cs)
PH (1) PH12274A (cs)
PL (1) PL99664B1 (cs)
PT (1) PT65027B (cs)
RO (1) RO73278A (cs)
SE (1) SE421695B (cs)
SU (1) SU638260A3 (cs)
YU (1) YU100676A (cs)
ZA (1) ZA762320B (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091098A (en) * 1977-04-25 1978-05-23 Merck & Co., Inc. 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
US4163849A (en) 1978-03-17 1979-08-07 Merck & Co., Inc. Piperazinylpyrazines
US4252816A (en) * 1979-12-03 1981-02-24 Merck & Co., Inc. Tetrahydro-1H-1,4-diazepino(1,7-a)benzimidazoles useful as analgesic agents
US4339579A (en) 1980-12-29 1982-07-13 American Home Products Corporation 2,6-Bis-(pyrrolopyrazinyl)pyrazines
EP0094498A3 (en) * 1982-05-06 1985-04-03 American Cyanamid Company Antiatherosclerotic 1-piperazine derivatives
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
US4788290A (en) * 1987-12-11 1988-11-29 American Home Products Corporation Serotonergic pyrazine derivatives
EP0580465A1 (fr) * 1992-06-25 1994-01-26 Sanofi Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés
ATE491689T1 (de) * 1997-10-27 2011-01-15 Neurosearch As Heteroaryl diazacycloalkane als cholinergische ligande für nikotin-acetylcholin-rezeptoren
AU773830B2 (en) * 1999-04-26 2004-06-10 Neurosearch A/S Heteroaryl diazacycloalkanes, their preparation and use
KR20030031886A (ko) * 2000-02-16 2003-04-23 뉴로젠 코포레이션 치환된 아릴피라진
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
SE0202287D0 (sv) * 2002-07-19 2002-07-19 Biovitrum Ab New compounds
ATE353693T1 (de) 2002-07-19 2007-03-15 Biovitrum Ab Neue piperazinyl-pyrazinon-derivate zur behandlung von 5-ht2a rezeptor-bedingten erkrankungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2606906A (en) * 1948-10-14 1952-08-12 American Cyanamid Co 1-(2-pyridyl) piperazine and process of preparing same

Also Published As

Publication number Publication date
CS195726B2 (en) 1980-02-29
FR2308367A1 (fr) 1976-11-19
RO73278A (ro) 1982-09-09
AU1296676A (en) 1977-10-20
HK60380A (en) 1980-11-07
DE2617205C3 (de) 1981-01-29
AR210349A1 (es) 1977-07-29
HU172684B (hu) 1978-11-28
IE42979L (en) 1976-10-21
NL7603800A (nl) 1976-10-25
KE3088A (en) 1980-11-07
SU638260A3 (ru) 1978-12-15
DD124599A5 (cs) 1977-03-02
MY8100225A (en) 1981-12-31
GB1492528A (en) 1977-11-23
LU74795A1 (cs) 1977-02-07
CY1090A (en) 1980-12-27
IL49391A0 (en) 1976-06-30
BE840904A (fr) 1976-08-16
CH619462A5 (en) 1980-09-30
ES459406A1 (es) 1978-08-16
DK164476A (da) 1976-10-22
ES459407A1 (es) 1978-08-16
ES447150A1 (es) 1977-09-16
BG34185A3 (en) 1983-07-15
PH12274A (en) 1978-12-12
DE2617205A1 (de) 1976-10-28
AT353795B (de) 1979-12-10
DK143899C (da) 1982-04-13
DK143899B (da) 1981-10-26
NL167692C (nl) 1982-01-18
SE7604093L (sv) 1976-10-22
AU496854B2 (en) 1978-11-02
ATA288376A (de) 1979-05-15
NO146599B (no) 1982-07-26
FI62666B (fi) 1982-10-29
FR2308367B1 (cs) 1979-09-21
YU100676A (en) 1982-08-31
FI62666C (fi) 1983-02-10
ES459405A1 (es) 1978-08-16
PT65027A (en) 1976-05-01
CA1059128A (en) 1979-07-24
GR59900B (en) 1978-03-16
NO761207L (cs) 1976-10-22
JPS5522475B2 (cs) 1980-06-17
JPS51136688A (en) 1976-11-26
PL99664B1 (pl) 1978-07-31
NO146599C (no) 1982-11-03
ZA762320B (en) 1977-11-30
NL167692B (nl) 1981-08-17
SE421695B (sv) 1982-01-25
FI760978A (cs) 1976-10-22
DE2617205B2 (de) 1980-05-08
PT65027B (en) 1978-04-03
IE42979B1 (en) 1980-11-19
IL49391A (en) 1979-09-30

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