EE9800248A - Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine - Google Patents

Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine

Info

Publication number
EE9800248A
EE9800248A EE9800248A EE9800248A EE9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A
Authority
EE
Estonia
Prior art keywords
freeze
preparation
ultrasound contrast
contrast medium
dried
Prior art date
Application number
EE9800248A
Other languages
English (en)
Estonian (et)
Inventor
Helge Gulliksen Per
Undheim Br�nden Jorunn
Kjersti Fahlvik Anne
Swaerd-Nordmo Marit
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603466.5A external-priority patent/GB9603466D0/en
Priority claimed from GBGB9611894.8A external-priority patent/GB9611894D0/en
Priority claimed from GBGB9624919.8A external-priority patent/GB9624919D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of EE9800248A publication Critical patent/EE9800248A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Light Receiving Elements (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
EE9800248A 1996-02-19 1997-02-19 Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine EE9800248A (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9603466.5A GB9603466D0 (en) 1996-02-19 1996-02-19 Improvements in or relating to contrast agents
GBGB9611894.8A GB9611894D0 (en) 1996-06-07 1996-06-07 Improvements in or relating to contrast agents
GBGB9624919.8A GB9624919D0 (en) 1996-11-29 1996-11-29 Product
PCT/GB1997/000458 WO1997029782A1 (fr) 1996-02-19 1997-02-19 Milieu de contraste stabilise thermiquement

Publications (1)

Publication Number Publication Date
EE9800248A true EE9800248A (et) 1999-02-15

Family

ID=27268136

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800248A EE9800248A (et) 1996-02-19 1997-02-19 Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine

Country Status (18)

Country Link
EP (1) EP0885016B1 (fr)
JP (1) JP4250747B2 (fr)
KR (1) KR100501863B1 (fr)
CN (1) CN1092988C (fr)
AT (1) ATE237362T1 (fr)
AU (1) AU722735B2 (fr)
CA (1) CA2246778A1 (fr)
CZ (1) CZ262698A3 (fr)
DE (1) DE69720979T2 (fr)
EA (1) EA000900B1 (fr)
EE (1) EE9800248A (fr)
ES (1) ES2197331T3 (fr)
HU (1) HUP9900812A3 (fr)
IL (1) IL125800A0 (fr)
NO (1) NO313815B1 (fr)
NZ (1) NZ331372A (fr)
PL (1) PL328309A1 (fr)
WO (1) WO1997029782A1 (fr)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ28999A3 (cs) 1996-08-02 1999-07-14 Nycomed Imaging As Použití kontrastního prostředku
GB9717542D0 (en) 1997-08-19 1997-10-22 Nycomed Imaging As Process
US6815435B2 (en) 2000-07-13 2004-11-09 Daiichi Pharmaceutical Co., Ltd. Pharmaceutical compositions containing DDS compounds
US6793626B2 (en) 2001-01-17 2004-09-21 Fuji Photo Film Co., Ltd. Ultrasonic scatterer, ultrasonic imaging method and ultrasonic imaging apparatus
ATE299378T1 (de) * 2001-01-31 2005-07-15 Bracco Research Sa Lyophilisierbares kontrastmittel, gasgefüllte mikrobläschen enthaltend
EP1572001A1 (fr) 2002-11-29 2005-09-14 Amersham Health AS Procede de synchronisation d'ultrasons
KR101076053B1 (ko) * 2003-02-04 2011-10-21 브라코 인터내셔날 비.브이. 초음파 조영제 및 그것의 제조방법
AU2004308756B2 (en) 2003-12-22 2010-06-24 Bracco Suisse S.A. Gas-filled microvesicle assembly for contrast imaging
JP4837663B2 (ja) 2004-08-18 2011-12-14 ブラッコ・シュイス・ソシエテ・アノニム 造影画像化のためのガス充填微小胞組成物
WO2006076826A1 (fr) * 2005-01-18 2006-07-27 Institute Of Pharmacology Toxicology, Academy Of Military Medical Sciences Composition de contraste pour ultrasons utilisant un phospholipide filmogene et procede de preparation de celle-ci
EP2061517B1 (fr) 2006-09-05 2010-06-02 Bracco Research S.A. Microvesicules remplies de gaz contenant des lipides modifies par polymeres
WO2008075192A2 (fr) 2006-12-19 2008-06-26 Bracco International Bv Composés de ciblage et composés thérapeutiques, et microvésicules remplies de gaz comprenant lesdits composés
EP2197473A2 (fr) 2007-09-11 2010-06-23 Mondobiotech Laboratories AG Utilisations therapeutiques d'un peptide natriuretique de type b et l'hormone de croissance humaine 1-43
US20100184698A1 (en) 2007-09-11 2010-07-22 Dorian Bevec Use of a deslorelin and mastoparan as a therapeutic agent
RU2010114010A (ru) 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение октреотида в качестве терапевтического средства
WO2009039982A2 (fr) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Utilisation d'un peptide en tant qu'agent thérapeutique
WO2009043447A2 (fr) 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Utilisation d'un peptide en tant qu'agent thérapeutique
KR20100061478A (ko) 2007-09-11 2010-06-07 몬도바이오테크 래보래토리즈 아게 치료제로서의 세크레틴 및 임의의 유로딜라틴의 용도
RU2010114013A (ru) 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение нейротрофического фактора для холинергических нейронов сетчатки (nfrcn) и хорионического гонадотропина бета (109-145) в качестве терапевтических средств
RU2010114006A (ru) 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение пептида в качестве терапевтического средства
AU2008303955A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of melanocyte-stimulating hormone release-inhibiting factor as a therapeutic agent in the treatment of Pseudomonas aeruginosa infection
WO2009040085A2 (fr) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Utilisation d'un peptide en tant qu'agent thérapeutique
US20100190722A1 (en) 2007-09-11 2010-07-29 Dorian Bevec Substance p and thyrotropin releasing hormone for therapeutic applications
KR20100061679A (ko) 2007-09-11 2010-06-08 몬도바이오테크 래보래토리즈 아게 치료적 적용을 위한 티로트로핀 방출 호르몬
EP2090322A1 (fr) 2008-02-18 2009-08-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Utilisation de ligands du récepteur de la FSH pour le diagnostic et le traitement du cancer
CA2748995C (fr) 2008-10-07 2018-01-16 Bracco Suisse Sa Construction de ciblage comprenant un anticorps anti-polymere et des liposomes ou des microvesicules se liant a ceux-ci
CN101649293B (zh) * 2009-09-02 2012-07-18 中国农业大学 一种微生物冷冻干燥保护剂及其应用
CA2806639C (fr) 2010-08-09 2020-10-20 Bracco Suisse Sa Microvesicules ciblees remplies de gaz
EP2426202A1 (fr) 2010-09-03 2012-03-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Kinases en tant que cibles pour thérapie antidiabétique
BR112013016244B1 (pt) 2010-12-24 2021-12-21 Bracco Suisse Sa Formulação farmacêutica compreendendo microvesículas cheias de gás e precursor da mesma
CA2852777C (fr) 2011-10-21 2020-10-27 Celator Pharmaceuticals Inc. Liposomes lyophilises
EP2589383A1 (fr) 2011-11-06 2013-05-08 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin Analogue de rapamycine spécifique au sous-type de FKBP à utiliser dans le traitement des maladies
GB201405735D0 (en) * 2014-03-31 2014-05-14 Ge Healthcare As Ultrasound precursor preparation method
GB201411423D0 (en) 2014-06-26 2014-08-13 Ge Healthcare As Lipid sterilisation method
EP3020813A1 (fr) 2014-11-16 2016-05-18 Neurovision Pharma GmbH Oligonculéotides antisens en tant qu'inhibiteurs de la signalisation de TGF-R
JP2017537907A (ja) 2014-12-22 2017-12-21 ブラッコ・スイス・ソシエテ・アノニムＢｒａｃｃｏ Ｓｕｉｓｓｅ ＳＡ ワクチンとしての使用のためのガス入りの微小胞
CA3091952A1 (fr) 2018-03-07 2019-09-12 Bracco Suisse Sa Preparation de microvesicules de taille controlee
JP2022538770A (ja) 2019-06-25 2022-09-06 ブラッコ・スイス・ソシエテ・アノニム 校正されたガス充填微小胞を調製するための凍結乾燥組成物
US20220409749A1 (en) 2019-06-25 2022-12-29 Bracco Suisse Sa Freeze-dried composition for preparing calibrated gas-filled microvesicles
US10953023B1 (en) 2020-01-28 2021-03-23 Applaud Medical, Inc. Phospholipid compounds and formulations
CN112891565A (zh) * 2021-04-09 2021-06-04 上海师范大学 锌-二甲基吡啶胺在制备诊断血栓性疾病药物中的应用
EP4105328A1 (fr) 2021-06-15 2022-12-21 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Oligonucléotides antisens pour la prévention d'un dysfonctionnement rénal favorisé par le dysfonctionnement endothélial par la suppression de l'ephrine-b2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
JPH06211645A (ja) * 1993-01-14 1994-08-02 Mitsubishi Kasei Corp リポソーム凍結乾燥製剤

Also Published As

Publication number Publication date
EP0885016B1 (fr) 2003-04-16
KR100501863B1 (ko) 2005-09-27
EP0885016A1 (fr) 1998-12-23
IL125800A0 (en) 1999-04-11
EA199800739A1 (ru) 1999-02-25
WO1997029782A1 (fr) 1997-08-21
DE69720979D1 (de) 2003-05-22
ATE237362T1 (de) 2003-05-15
HUP9900812A3 (en) 1999-11-29
DE69720979T2 (de) 2004-02-26
CA2246778A1 (fr) 1997-08-21
ES2197331T3 (es) 2004-01-01
EA000900B1 (ru) 2000-06-26
JP4250747B2 (ja) 2009-04-08
PL328309A1 (en) 1999-01-18
CZ262698A3 (cs) 1999-03-17
NO313815B1 (no) 2002-12-09
CN1213971A (zh) 1999-04-14
AU1805197A (en) 1997-09-02
CN1092988C (zh) 2002-10-23
AU722735B2 (en) 2000-08-10
JP2000506122A (ja) 2000-05-23
NZ331372A (en) 2000-01-28
KR19990082670A (ko) 1999-11-25
NO983584D0 (no) 1998-08-05
NO983584L (no) 1998-10-16
HUP9900812A2 (hu) 1999-07-28

Similar Documents

Publication Publication Date Title
EE9800248A (et) Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine
DK1133316T3 (da) Adenovirus-formulering til genterapi
DE69717815T2 (de) Verbesserungen von kreatin-zusammensetzungen
ATE91712T1 (de) Enzymstabilisierung.
ID27444A (id) Zat pewarna
HUP0100284A2 (hu) Aktivált protein C készítmények
DK59691A (da) Fremgangsmaade til fremstilling af liposomer med forbedret stabilitet under toerring
NO883926L (no) Fremgangsmaate for fremstilling av stabilisert humanproteinpreparat.
ATE110412T1 (de) Translation von mrna.
PL319347A1 (en) Method of obtaining salt-stabilised enzymes
DE69531314D1 (de) Verwendung von metallionen chelatoren zur stabilisierung von interferon-enthaltenden pharmazeutischen zubereitungen
HUP0001259A2 (hu) Készítmény keratinszálak oxidációs festésére és festési eljárás a készítmény felhasználásával
EP1308170A3 (fr) Composition d'un facteur de coagulation du sang contenant du tréhalose
DE69715482T2 (de) Herstellung von 1,1,1,3,3-Pentachlorbutan und von 1,1,1,3,3-Pentafluorbutan
CA2040815A1 (fr) Methode de stabilisation des enzymes
PL341703A1 (en) Laccase containing composition for oxidatingly dyeing creatine fibre and dyeing method employing such composition
HUP0001205A2 (hu) Készítmény keratintartalmú rostok oxidációs festéséhez
EE9800334A (et) Helicobacter pylor' iga seotud nukleiinhapete ja aminohapete järjestused ja nendest tuletatud vaktsiinikompositsioonid
HUP0002411A2 (hu) Keratinszálak oxidációs festésére alkalmas készítmény és eljárás a készítmény alkalmazásával
HUP0001340A2 (hu) Készítmény keratintartalmú rostok oxidációs festéséhez és festési eljárás a készítmény alkalmazásával
DE3889408D1 (de) Flüssigkristalline Mischungen enthaltend optisch aktive 1-[2-Halogen-substituierte-phenyl]-äthanole und Derivate davon.
DE69730766D1 (de) Maltooligosyltaranose und Maltooligosylparatinose enthaltende Polysaccharidzusammensetzung, Herstellung und Verwendung
DE59706478D1 (de) Chromanyl-ascorbinsäurederivate, deren Herstellung und Verwendung
FR2716965B1 (fr) Engin largable à stabilisation et freinage aérodynamique.
AU2001252317A1 (en) Oxidation dyeing composition for keratinous fibres and method using same