EE200000342A - Asatsükloalkaanidest tuletatud uretaanid, nende tio- ja ditioanaloogid, nende valmistamine ja kasutamine 2,3-epoksüskvaleenlanesterooltsüklaasi inhibiitoritena - Google Patents
Asatsükloalkaanidest tuletatud uretaanid, nende tio- ja ditioanaloogid, nende valmistamine ja kasutamine 2,3-epoksüskvaleenlanesterooltsüklaasi inhibiitoritenaInfo
- Publication number
- EE200000342A EE200000342A EEP200000342A EEP200000342A EE200000342A EE 200000342 A EE200000342 A EE 200000342A EE P200000342 A EEP200000342 A EE P200000342A EE P200000342 A EEP200000342 A EE P200000342A EE 200000342 A EE200000342 A EE 200000342A
- Authority
- EE
- Estonia
- Prior art keywords
- azethanes
- lesterol
- azacycloalkanes
- thio
- derived
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/132—Heterocyclic compounds containing only one nitrogen as hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Birds (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
- Hydrogenated Pyridines (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19754796A DE19754796A1 (de) | 1997-12-10 | 1997-12-10 | Neue, von Azacycloalkanen abgeleitete Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
| PCT/EP1998/007965 WO1999029669A1 (de) | 1997-12-10 | 1998-12-08 | Von azacycloalkanen abgeleitete urethane, ihre thio- und dithioanaloga, deren herstellung und deren verwendung als 2,3-epoxisqualen-lanosterol-cyclase inhibitoren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200000342A true EE200000342A (et) | 2001-08-15 |
Family
ID=7851381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200000342A EE200000342A (et) | 1997-12-10 | 1998-12-08 | Asatsükloalkaanidest tuletatud uretaanid, nende tio- ja ditioanaloogid, nende valmistamine ja kasutamine 2,3-epoksüskvaleenlanesterooltsüklaasi inhibiitoritena |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1060162B1 (et) |
| JP (1) | JP3418688B2 (et) |
| KR (1) | KR20010032977A (et) |
| CN (1) | CN1281434A (et) |
| AR (1) | AR017827A1 (et) |
| AT (1) | ATE234816T1 (et) |
| AU (1) | AU1759499A (et) |
| BG (1) | BG104500A (et) |
| BR (1) | BR9813495A (et) |
| CA (1) | CA2309388A1 (et) |
| CO (1) | CO5370694A1 (et) |
| DE (2) | DE19754796A1 (et) |
| DK (1) | DK1060162T3 (et) |
| EA (1) | EA200000631A1 (et) |
| EE (1) | EE200000342A (et) |
| ES (1) | ES2190130T3 (et) |
| HR (1) | HRP20000377A2 (et) |
| HU (1) | HUP0100335A3 (et) |
| IL (1) | IL135738A0 (et) |
| NO (1) | NO20002967L (et) |
| PL (1) | PL341060A1 (et) |
| PT (1) | PT1060162E (et) |
| SK (1) | SK8612000A3 (et) |
| TR (1) | TR200001635T2 (et) |
| WO (1) | WO1999029669A1 (et) |
| YU (1) | YU35600A (et) |
| ZA (1) | ZA9811262B (et) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040072865A1 (en) * | 2001-01-15 | 2004-04-15 | Bouillot Anne Marie Jeanne | Aryl piperidine derivatives as inducers of ldl-receptor expression |
| WO2002055496A1 (en) * | 2001-01-15 | 2002-07-18 | Glaxo Group Limited | Aryl piperidine and piperazine derivatives as inducers of ldl-receptor expression |
| EP1351937A1 (en) * | 2001-01-15 | 2003-10-15 | Glaxo Group Limited | Aryl piperidine derivatives as inducers of ldl-receptor expression |
| DE10132686A1 (de) * | 2001-07-05 | 2003-01-16 | Boehringer Ingelheim Pharma | Heteroarylcarbonsäureamide, ihre Herstellung und ihre Verwendung als Arzneimittel |
| JP4664634B2 (ja) * | 2003-09-05 | 2011-04-06 | 富山化学工業株式会社 | 新規なベンズアミジン誘導体またはその塩 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04312572A (ja) * | 1991-04-12 | 1992-11-04 | Takeda Chem Ind Ltd | 環状アミン化合物 |
| DE4407138A1 (de) * | 1994-03-04 | 1995-09-07 | Thomae Gmbh Dr K | Aryliden-1-azacycloalkane und Arylalkyl-1-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
| DE4407136A1 (de) * | 1994-03-04 | 1995-09-07 | Thomae Gmbh Dr K | Aroyl-1-azacycloalkane, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
-
1997
- 1997-12-10 DE DE19754796A patent/DE19754796A1/de not_active Withdrawn
-
1998
- 1998-12-08 PT PT98962423T patent/PT1060162E/pt unknown
- 1998-12-08 SK SK861-2000A patent/SK8612000A3/sk unknown
- 1998-12-08 CA CA002309388A patent/CA2309388A1/en not_active Abandoned
- 1998-12-08 JP JP2000524266A patent/JP3418688B2/ja not_active Expired - Fee Related
- 1998-12-08 AT AT98962423T patent/ATE234816T1/de not_active IP Right Cessation
- 1998-12-08 PL PL98341060A patent/PL341060A1/xx unknown
- 1998-12-08 EA EA200000631A patent/EA200000631A1/ru unknown
- 1998-12-08 YU YU35600A patent/YU35600A/sh unknown
- 1998-12-08 EP EP98962423A patent/EP1060162B1/de not_active Expired - Lifetime
- 1998-12-08 TR TR2000/01635T patent/TR200001635T2/xx unknown
- 1998-12-08 WO PCT/EP1998/007965 patent/WO1999029669A1/de not_active Application Discontinuation
- 1998-12-08 IL IL13573898A patent/IL135738A0/xx unknown
- 1998-12-08 AU AU17594/99A patent/AU1759499A/en not_active Abandoned
- 1998-12-08 CN CN98811959A patent/CN1281434A/zh active Pending
- 1998-12-08 EE EEP200000342A patent/EE200000342A/et unknown
- 1998-12-08 DE DE59807591T patent/DE59807591D1/de not_active Expired - Fee Related
- 1998-12-08 ES ES98962423T patent/ES2190130T3/es not_active Expired - Lifetime
- 1998-12-08 KR KR1020007006326A patent/KR20010032977A/ko not_active Application Discontinuation
- 1998-12-08 HU HU0100335A patent/HUP0100335A3/hu unknown
- 1998-12-08 BR BR9813495-7A patent/BR9813495A/pt not_active IP Right Cessation
- 1998-12-08 DK DK98962423T patent/DK1060162T3/da active
- 1998-12-09 CO CO98073126A patent/CO5370694A1/es not_active Application Discontinuation
- 1998-12-09 AR ARP980106228A patent/AR017827A1/es not_active Withdrawn
- 1998-12-09 ZA ZA9811262A patent/ZA9811262B/xx unknown
-
2000
- 2000-06-02 BG BG104500A patent/BG104500A/bg active Pending
- 2000-06-07 HR HR20000377A patent/HRP20000377A2/hr not_active Application Discontinuation
- 2000-06-09 NO NO20002967A patent/NO20002967L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE234816T1 (de) | 2003-04-15 |
| AR017827A1 (es) | 2001-10-24 |
| YU35600A (sh) | 2002-09-19 |
| NO20002967D0 (no) | 2000-06-09 |
| IL135738A0 (en) | 2001-05-20 |
| AU1759499A (en) | 1999-06-28 |
| HUP0100335A2 (hu) | 2001-07-30 |
| DE59807591D1 (de) | 2003-04-24 |
| PL341060A1 (en) | 2001-03-26 |
| TR200001635T2 (tr) | 2000-11-21 |
| DK1060162T3 (da) | 2003-07-14 |
| CN1281434A (zh) | 2001-01-24 |
| JP2001525397A (ja) | 2001-12-11 |
| BR9813495A (pt) | 2000-10-10 |
| ZA9811262B (en) | 2000-06-09 |
| HUP0100335A3 (en) | 2001-11-28 |
| WO1999029669A1 (de) | 1999-06-17 |
| JP3418688B2 (ja) | 2003-06-23 |
| CA2309388A1 (en) | 1999-06-17 |
| ES2190130T3 (es) | 2003-07-16 |
| KR20010032977A (ko) | 2001-04-25 |
| DE19754796A1 (de) | 1999-06-17 |
| NO20002967L (no) | 2000-08-09 |
| EP1060162A1 (de) | 2000-12-20 |
| HRP20000377A2 (en) | 2000-12-31 |
| PT1060162E (pt) | 2003-08-29 |
| SK8612000A3 (en) | 2000-11-07 |
| EP1060162B1 (de) | 2003-03-19 |
| BG104500A (bg) | 2001-03-30 |
| CO5370694A1 (es) | 2004-02-27 |
| EA200000631A1 (ru) | 2000-12-25 |
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