EE05241B1 - Distamtsiini a-halogenoakrlolderivaadi kasutamine - Google Patents
Distamtsiini a-halogenoakrlolderivaadi kasutamineInfo
- Publication number
- EE05241B1 EE05241B1 EEP200300129A EEP200300129A EE05241B1 EE 05241 B1 EE05241 B1 EE 05241B1 EE P200300129 A EEP200300129 A EE P200300129A EE P200300129 A EEP200300129 A EE P200300129A EE 05241 B1 EE05241 B1 EE 05241B1
- Authority
- EE
- Estonia
- Prior art keywords
- derivative
- halogenoacryl
- distamycin
- administration
- tumors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/676,770 US6576612B1 (en) | 2000-10-02 | 2000-10-02 | Antitumor therapy comprising distamycin derivatives |
| PCT/EP2001/010988 WO2002028389A1 (en) | 2000-10-02 | 2001-09-21 | Antitumor therapy comprising distamycin derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200300129A EE200300129A (et) | 2003-06-16 |
| EE05241B1 true EE05241B1 (et) | 2009-12-15 |
Family
ID=24715919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300129A EE05241B1 (et) | 2000-10-02 | 2001-09-21 | Distamtsiini a-halogenoakrlolderivaadi kasutamine |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US6576612B1 (zh) |
| EP (1) | EP1345604B1 (zh) |
| JP (1) | JP2004510734A (zh) |
| KR (1) | KR100827560B1 (zh) |
| CN (1) | CN1468099A (zh) |
| AT (1) | ATE339202T1 (zh) |
| AU (2) | AU2002221622B2 (zh) |
| BR (1) | BR0114389A (zh) |
| CA (1) | CA2424116A1 (zh) |
| CZ (1) | CZ299686B6 (zh) |
| DE (1) | DE60123117T2 (zh) |
| EA (1) | EA006295B1 (zh) |
| EE (1) | EE05241B1 (zh) |
| ES (1) | ES2267841T3 (zh) |
| HU (1) | HUP0301247A2 (zh) |
| IL (1) | IL154755A0 (zh) |
| MX (1) | MXPA03002824A (zh) |
| MY (1) | MY134690A (zh) |
| NO (1) | NO20031410D0 (zh) |
| PE (1) | PE20020487A1 (zh) |
| PL (1) | PL363926A1 (zh) |
| SK (1) | SK5032003A3 (zh) |
| WO (1) | WO2002028389A1 (zh) |
| ZA (1) | ZA200303405B (zh) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0015446D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
| GB0015447D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
| US6576612B1 (en) * | 2000-10-02 | 2003-06-10 | Pharmacia Italia S.P.A. | Antitumor therapy comprising distamycin derivatives |
| US20070249651A1 (en) * | 2001-06-20 | 2007-10-25 | Nerviano Medical Sciences S.R.I. | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
| US6969592B2 (en) * | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
| DE60318561T2 (de) * | 2002-04-02 | 2009-01-08 | Nerviano Medical Sciences S.R.L., Nerviano | Kombinierte tumortherapie auf der basis von distamycin-acryloyl derivaten und radiotherapie |
| AU2003288263A1 (en) * | 2002-10-16 | 2004-05-04 | Pharmacia Italia S.P.A. | Use of substituted acrylolyl distamycin derivatives in combination with demethylating agents, in the treatment of cancer |
| BRPI0520806A2 (pt) * | 2005-12-27 | 2009-06-09 | Ct Nac De Investigaciones Oncologicas | derivados pirrólicos, processos para a preparação de compostos, seu uso e composição farmacêutica que os contém |
| MD24Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare |
| MD23Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare |
| MD35Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare |
| MD36Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8906709D0 (en) * | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
| GB9615692D0 (en) * | 1996-07-25 | 1996-09-04 | Pharmacia Spa | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB9806689D0 (en) * | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents |
| GB9928703D0 (en) * | 1999-12-03 | 2000-02-02 | Pharmacia & Upjohn Spa | Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents |
| US6576612B1 (en) * | 2000-10-02 | 2003-06-10 | Pharmacia Italia S.P.A. | Antitumor therapy comprising distamycin derivatives |
-
2000
- 2000-10-02 US US09/676,770 patent/US6576612B1/en not_active Expired - Lifetime
-
2001
- 2001-09-21 BR BR0114389-1A patent/BR0114389A/pt not_active Application Discontinuation
- 2001-09-21 EE EEP200300129A patent/EE05241B1/xx not_active IP Right Cessation
- 2001-09-21 EA EA200300427A patent/EA006295B1/ru not_active IP Right Cessation
- 2001-09-21 PL PL01363926A patent/PL363926A1/xx not_active Application Discontinuation
- 2001-09-21 AU AU2002221622A patent/AU2002221622B2/en not_active Ceased
- 2001-09-21 SK SK503-2003A patent/SK5032003A3/sk unknown
- 2001-09-21 DE DE60123117T patent/DE60123117T2/de not_active Expired - Lifetime
- 2001-09-21 CN CNA018167551A patent/CN1468099A/zh active Pending
- 2001-09-21 JP JP2002532214A patent/JP2004510734A/ja not_active Withdrawn
- 2001-09-21 HU HU0301247A patent/HUP0301247A2/hu unknown
- 2001-09-21 CA CA002424116A patent/CA2424116A1/en not_active Abandoned
- 2001-09-21 KR KR1020037004710A patent/KR100827560B1/ko not_active IP Right Cessation
- 2001-09-21 US US10/381,272 patent/US7399748B2/en not_active Expired - Fee Related
- 2001-09-21 AT AT01986259T patent/ATE339202T1/de active
- 2001-09-21 CZ CZ20030909A patent/CZ299686B6/cs not_active IP Right Cessation
- 2001-09-21 WO PCT/EP2001/010988 patent/WO2002028389A1/en active IP Right Grant
- 2001-09-21 IL IL15475501A patent/IL154755A0/xx not_active IP Right Cessation
- 2001-09-21 MX MXPA03002824A patent/MXPA03002824A/es unknown
- 2001-09-21 EP EP01986259A patent/EP1345604B1/en not_active Expired - Lifetime
- 2001-09-21 AU AU2162202A patent/AU2162202A/xx active Pending
- 2001-09-21 ES ES01986259T patent/ES2267841T3/es not_active Expired - Lifetime
- 2001-09-28 PE PE2001000967A patent/PE20020487A1/es not_active Application Discontinuation
- 2001-09-28 MY MYPI20014542A patent/MY134690A/en unknown
-
2003
- 2003-03-27 NO NO20031410A patent/NO20031410D0/no not_active Application Discontinuation
- 2003-05-02 ZA ZA200303405A patent/ZA200303405B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MY134690A (en) | 2007-12-31 |
| CZ2003909A3 (cs) | 2003-08-13 |
| ZA200303405B (en) | 2004-05-03 |
| CZ299686B6 (cs) | 2008-10-22 |
| EA200300427A1 (ru) | 2003-10-30 |
| US20040006023A1 (en) | 2004-01-08 |
| NO20031410L (no) | 2003-03-27 |
| IL154755A0 (en) | 2003-10-31 |
| AU2002221622B2 (en) | 2007-05-17 |
| DE60123117D1 (de) | 2006-10-26 |
| EA006295B1 (ru) | 2005-10-27 |
| CN1468099A (zh) | 2004-01-14 |
| MXPA03002824A (es) | 2003-07-14 |
| PE20020487A1 (es) | 2002-05-23 |
| EE200300129A (et) | 2003-06-16 |
| US6576612B1 (en) | 2003-06-10 |
| JP2004510734A (ja) | 2004-04-08 |
| NO20031410D0 (no) | 2003-03-27 |
| PL363926A1 (en) | 2004-11-29 |
| KR20030096222A (ko) | 2003-12-24 |
| US7399748B2 (en) | 2008-07-15 |
| ES2267841T3 (es) | 2007-03-16 |
| DE60123117T2 (de) | 2007-02-08 |
| EP1345604B1 (en) | 2006-09-13 |
| ATE339202T1 (de) | 2006-10-15 |
| HUP0301247A2 (hu) | 2003-09-29 |
| SK5032003A3 (en) | 2003-08-05 |
| KR100827560B1 (ko) | 2008-05-07 |
| EP1345604A1 (en) | 2003-09-24 |
| CA2424116A1 (en) | 2002-04-11 |
| BR0114389A (pt) | 2004-02-03 |
| AU2162202A (en) | 2002-04-15 |
| WO2002028389A1 (en) | 2002-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HK1A | Erratum in gazette | ||
| GB1A | Change in the ownership or in the address of the owner | ||
| KB4A | Valid patent at the end of a year |
Effective date: 20101231 |
|
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20110921 |