EE04293B1 - Stabiilsed lüofiliseeritud ravimvormid - Google Patents

Stabiilsed lüofiliseeritud ravimvormid

Info

Publication number
EE04293B1
EE04293B1 EE9800123A EE9800123A EE04293B1 EE 04293 B1 EE04293 B1 EE 04293B1 EE 9800123 A EE9800123 A EE 9800123A EE 9800123 A EE9800123 A EE 9800123A EE 04293 B1 EE04293 B1 EE 04293B1
Authority
EE
Estonia
Prior art keywords
dosage forms
lyophilized dosage
stable lyophilized
stable
forms
Prior art date
Application number
EE9800123A
Other languages
English (en)
Estonian (et)
Other versions
EE9800123A (et
Inventor
Bouloumie Colette
Breul Thierry
Colliere Laurence
Faure Philippe
Original Assignee
Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9484220&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE04293(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi filed Critical Sanofi
Publication of EE9800123A publication Critical patent/EE9800123A/xx
Publication of EE04293B1 publication Critical patent/EE04293B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EE9800123A 1995-11-03 1996-10-30 Stabiilsed lüofiliseeritud ravimvormid EE04293B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9513022A FR2740686B1 (fr) 1995-11-03 1995-11-03 Formulation pharmaceutique lyophilisee stable
PCT/FR1996/001706 WO1997017064A1 (fr) 1995-11-03 1996-10-30 Formulation pharmaceutique lyophilisee stable

Publications (2)

Publication Number Publication Date
EE9800123A EE9800123A (et) 1998-10-15
EE04293B1 true EE04293B1 (et) 2004-06-15

Family

ID=9484220

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800123A EE04293B1 (et) 1995-11-03 1996-10-30 Stabiilsed lüofiliseeritud ravimvormid

Country Status (32)

Country Link
US (1) US6284277B1 (de)
EP (1) EP0858325B1 (de)
JP (1) JP3357376B2 (de)
KR (1) KR100367752B1 (de)
CN (1) CN1124844C (de)
AR (1) AR004255A1 (de)
AT (1) ATE221374T1 (de)
AU (1) AU713383B2 (de)
BR (1) BR9611367A (de)
CA (1) CA2234140C (de)
CZ (1) CZ287178B6 (de)
DE (1) DE69622735T2 (de)
DK (1) DK0858325T3 (de)
EE (1) EE04293B1 (de)
ES (1) ES2180805T3 (de)
FR (1) FR2740686B1 (de)
HK (1) HK1015697A1 (de)
IL (1) IL124214A (de)
IS (1) IS1967B (de)
MX (1) MX9803344A (de)
MY (1) MY116578A (de)
NO (1) NO322582B1 (de)
NZ (1) NZ321616A (de)
PL (1) PL186284B1 (de)
PT (1) PT858325E (de)
RU (1) RU2163801C2 (de)
SK (1) SK283031B6 (de)
TR (1) TR199800782T2 (de)
TW (1) TW442295B (de)
UA (1) UA60297C2 (de)
WO (1) WO1997017064A1 (de)
ZA (1) ZA969176B (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743777B1 (en) * 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US6197787B1 (en) * 1997-03-03 2001-03-06 Sanofi-Synthelabo Pharmaceutical formulations containing poorly soluble drug substances
JP4939680B2 (ja) * 1997-05-27 2012-05-30 武田薬品工業株式会社 固形製剤
FR2764800B1 (fr) * 1997-06-23 1999-09-10 Sanofi Sa Composition pharmaceutique solide contenant des derives de benzofuranne
SE9702680D0 (sv) * 1997-07-11 1997-07-11 Astra Pharma Prod New formulation
DE19754324A1 (de) * 1997-12-08 1999-06-10 Byk Gulden Lomberg Chem Fab Neue Darreichungsform enthaltend einen säurelabilen Wirkstoff
JP4546643B2 (ja) 1997-12-08 2010-09-15 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 酸不安定な活性化合物を含有する新規の坐剤形
GB9804013D0 (en) * 1998-02-25 1998-04-22 Sanofi Sa Formulations
FR2781227B1 (fr) 1998-07-20 2002-02-22 Sanofi Sa Procede pour la preparation du sel potassique du lintitript
FR2782455B3 (fr) * 1998-08-20 2000-09-15 Sanofi Sa Composition pharmaceutique injectable a base d'un sel pharmaceutiquement acceptable du clopidogrel ou de ticlopidine
US6898762B2 (en) 1998-08-21 2005-05-24 United Video Properties, Inc. Client-server electronic program guide
FR2787329B1 (fr) * 1998-12-17 2001-02-09 Aventis Pharma Sa Nouvelle application therapeutique des heparines de bas poids moleculaire
CA2362481C (en) * 1999-03-03 2008-11-04 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
WO2000052037A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Echinocandin/carbohydrate complexes
FR2793685B1 (fr) * 1999-05-19 2001-08-24 Promindus Actions Promotionnel Compositions pharmaceutiques, destinees a l'administration par voie orale de phloroglucinol et leur preparation
FR2805539B1 (fr) * 2000-02-25 2005-06-10 Oreal Compositions de teinture des fibres keratiniques contenant des derives d'indolizine et procede de teinture
US6716884B1 (en) 2000-05-19 2004-04-06 Promindus (Actions Promotionnelles Dans L'industrie Et Le Commerce) Pharmaceutical compositions for oral administration of phloroglucinol and preparation thereof
AU2001278755A1 (en) * 2000-08-18 2002-03-04 Takeda Chemical Industries Ltd. Injections
MY137726A (en) * 2000-11-22 2009-03-31 Nycomed Gmbh Freeze-dried pantoprazole preparation and pantoprazole injection
WO2002041892A1 (fr) * 2000-11-24 2002-05-30 Yamanouchi Pharmaceutical Co., Ltd. Liquide hydrosoluble pour medecine interne
WO2003048135A1 (en) * 2001-11-14 2003-06-12 Teva Pharmaceutical Industries Ltd. Amorphous and crystalline forms of losartan potassium and process for their preparation
WO2003050110A1 (en) * 2001-12-10 2003-06-19 Dr. Reddy's Laboratories Ltd. Amorphous form of 2-n-butyl-3-( (2-(1h-tetrazol-5-yl) (1,1'-biphenyl)-4-yl) methyl) -1,3-diazaspiro (4,4') non-1-en-4-one
SG161101A1 (en) 2002-02-22 2010-05-27 Schering Corp Pharmaceutical formulations of antineoplastic agents, in particular temozolomide processes of making and using the same
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
US6991800B2 (en) * 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
GB2393181A (en) * 2002-09-19 2004-03-24 Cipla Ltd Amorphous clopidogrel
ATE374768T1 (de) 2002-10-03 2007-10-15 Hoffmann La Roche Indole-3-carbonsaüreamide als glucokinase (gk) aktivatoren
DE60316180T2 (de) * 2002-12-03 2008-05-29 F. Hoffmann-La Roche Ag Aminoalkoxyindol-derivate als 5-ht6-rezeptorliganden zur bekämpfung von zns-krankheiten
DE10305984A1 (de) * 2003-02-13 2004-09-02 Helm Ag Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
GB0304636D0 (en) * 2003-02-28 2003-04-02 Britannia Pharmaceuticals Ltd Pharmaceutical composition for nasal delivery
KR100732100B1 (ko) * 2003-05-07 2007-06-27 에자이 알앤드디 매니지먼트 가부시키가이샤 메틸코발라민 함유 동결 건조 제제 및 그의 제조 방법
JP2007504177A (ja) * 2003-09-02 2007-03-01 プリヴァ−ラケマ，エー．エス． 医薬組成物、その製造方法及び治療上の使用
WO2005065185A2 (en) * 2003-12-24 2005-07-21 Collegium Pharmaceuticals, Inc. Temperature-stable formulations, and methods of development thereof
US20050255161A1 (en) * 2004-05-10 2005-11-17 Servet Buyuktimkin Method for the long term stabilization of labile compounds at room temperature in pharmaceutical preparations containing water
DE602005025755D1 (de) 2004-06-04 2011-02-17 Teva Pharma Irbesartan enthaltende pharmazeutische zusammensetzung
US20060275331A1 (en) * 2004-08-31 2006-12-07 Borek Zaludek Pharmaceutical composition, method of manufacturing and therapeutic use thereof
ES2543813T3 (es) 2004-11-02 2015-08-24 Northwestern University Compuestos de piridazina para el tratamiento de enfermedades inflamatorias
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
US20070026026A1 (en) * 2005-08-01 2007-02-01 David Delmarre Oral liquid losartan compositions
EP1787641A1 (de) * 2005-11-22 2007-05-23 Helm AG Tazobactam-Piperacillin-Lyophilisat
US20080108664A1 (en) 2005-12-23 2008-05-08 Liu Belle B Solid-state form of AMG 706 and pharmaceutical compositions thereof
WO2007103711A2 (en) * 2006-03-01 2007-09-13 Dr. Reddy's Laboratories Ltd. Polymorphic forms of rimonabant
JP2009539869A (ja) * 2006-06-06 2009-11-19 スレショルド ファーマシューティカルズ インコーポレイティッド グルフォスファミドの単位用量形態
US20070287734A1 (en) * 2006-06-09 2007-12-13 Auspex Pharmaceuticals, Inc. Preparation and utility of substituted pyrazole compounds with cannabinoid receptor activity
EP2851087B1 (de) * 2006-11-07 2017-04-19 Sanofi Pasteur Biologics, LLC Impfstoffstabilisierung mittels Lyophilisierung
WO2008060934A2 (en) * 2006-11-14 2008-05-22 Acusphere, Inc. Formulations of tetrahydropyridine antiplatelet agents for parenteral or oral administration
US8765690B2 (en) * 2007-04-05 2014-07-01 Threshold Pharmaceuticals, Inc. Treatment of cancer with glufosfamide in patients not receiving insulin therapy
GB0715285D0 (en) * 2007-08-06 2007-09-12 Britannia Pharmaceuticals Ltd Improvements in or relating to powdered medicaments for nasal delivery
PL2112155T3 (pl) 2008-04-25 2011-03-31 Sandoz Ag Wodorosiarczan (VI) 2-acetoksy-5-(α-cyklopropylokarbonylo-2-fluorobenzylo)-4,5,6,7-tetrahydrotieno[3,2-c]pirydyny i sposób jego otrzymywania
JP5759464B2 (ja) 2009-09-21 2015-08-05 ジェイダブリュー ファーマシューティカル コーポレイション オキサリプラチンのナノ粒子及びその製造方法
WO2011101865A2 (en) 2010-02-19 2011-08-25 Cadila Healthcare Limited Stable pharmaceutical compositions of clopidogrel for parenteral delivery
CN102970992B (zh) 2010-05-12 2016-07-06 莱姆派克斯制药公司 四环素组合物
WO2013105998A2 (en) 2011-02-16 2013-07-18 Tyco Electronics Corporation Fiber optic closure
BR112013026363B1 (pt) 2011-04-15 2021-10-13 Janssen Pharmaceutica Nv Nanossuspensões compreendendo 4-[[4-[[4-(2-cianoetenil)-2,6-dimetilfenil]amino]-2-pirimidinil] amino] benzonitrila, seu processo de preparação e composição farmacêutica para administração por injeção intramuscular ou subcutânea
CN103230371B (zh) * 2012-05-18 2014-07-23 湖北一半天制药有限公司 注射用奥沙利铂冻干制剂的制备方法
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
CN106706785B (zh) * 2016-12-23 2019-02-26 东药集团沈阳施德药业有限公司 一种采用高效液相色谱检测厄贝沙坦氢氯噻嗪片中有关物质的方法
US10149857B2 (en) 2017-03-09 2018-12-11 Ampac Fine Chemicals Llc Lyophilized cyclophosphamide composition and methods of preparation thereof
US11110063B2 (en) 2017-08-25 2021-09-07 MAIA Pharmaceuticals, Inc. Storage stable sincalide formulations
JP2021505673A (ja) * 2017-12-07 2021-02-18 リーベン アイピー ホールディングカンパニー リミテッド ライアビリティ カンパニー 代謝性疾患の治療のための組成物および方法
US20230059869A1 (en) 2021-08-03 2023-02-23 Liqmeds Worldwide Limited Oral pharmaceutical solution of clopidogrel
CN114533683B (zh) * 2021-12-23 2023-08-01 李宏 一种注射用腺苷钴胺冻干制剂组合物及其制备方法
TW202339745A (zh) 2022-01-28 2023-10-16 大陸商上海柯君醫藥科技有限公司 抗血小板藥物的藥物組合物及其用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS532931B2 (de) * 1973-12-05 1978-02-01
GB2021581B (en) * 1978-05-17 1982-10-20 Wellcome Found Stabilisation of pgl derivatives
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide
JPH0296536A (ja) * 1988-09-29 1990-04-09 Green Cross Corp:The プラスミノゲン乾燥製剤
CA2013474C (en) * 1989-04-20 2000-01-18 Pharmacia Inc. Cyclophosphamide - alanine lyophilizates
US5558880A (en) 1989-12-22 1996-09-24 Janssen Pharmaceutica Inc. Pharmaceutical and other dosage forms
IL105553A (en) * 1992-05-06 1998-01-04 Janssen Pharmaceutica Inc Solid dosage forms consisting of a porous network of matrix that releases a substance that dissipates rapidly in water
US5885486A (en) * 1993-03-05 1999-03-23 Pharmaciaand Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
FR2719479B1 (fr) * 1994-05-04 1996-07-26 Sanofi Elf Formulation stable lyophilisée comprenant une protéine: kit de dosage.

Also Published As

Publication number Publication date
FR2740686B1 (fr) 1998-01-16
CA2234140A1 (fr) 1997-05-15
AU713383B2 (en) 1999-12-02
FR2740686A1 (fr) 1997-05-09
TW442295B (en) 2001-06-23
NO981967L (no) 1998-06-30
JPH11507945A (ja) 1999-07-13
ES2180805T3 (es) 2003-02-16
MX9803344A (es) 1998-09-30
PL186284B1 (pl) 2003-12-31
CZ123198A3 (cs) 1998-07-15
CZ287178B6 (en) 2000-10-11
CN1124844C (zh) 2003-10-22
HK1015697A1 (en) 1999-10-22
BR9611367A (pt) 1999-02-23
PL326451A1 (en) 1998-09-28
DE69622735T2 (de) 2003-04-03
KR19990067325A (ko) 1999-08-16
IS1967B (is) 2004-12-15
ATE221374T1 (de) 2002-08-15
RU2163801C2 (ru) 2001-03-10
ZA969176B (en) 1998-04-30
IL124214A (en) 2001-01-28
NO322582B1 (no) 2006-10-30
NO981967D0 (no) 1998-04-30
TR199800782T2 (xx) 1998-09-21
AU7499096A (en) 1997-05-29
SK52598A3 (en) 1998-10-07
KR100367752B1 (ko) 2003-03-15
DK0858325T3 (da) 2002-11-25
SK283031B6 (sk) 2003-02-04
EE9800123A (et) 1998-10-15
PT858325E (pt) 2002-12-31
WO1997017064A1 (fr) 1997-05-15
IS4729A (is) 1998-04-29
JP3357376B2 (ja) 2002-12-16
US6284277B1 (en) 2001-09-04
DE69622735D1 (de) 2002-09-05
UA60297C2 (uk) 2003-10-15
CA2234140C (fr) 2004-10-26
AR004255A1 (es) 1998-11-04
EP0858325B1 (de) 2002-07-31
NZ321616A (en) 1999-04-29
EP0858325A1 (de) 1998-08-19
CN1203527A (zh) 1998-12-30
MY116578A (en) 2004-02-28

Similar Documents

Publication Publication Date Title
EE04293B1 (et) Stabiilsed lüofiliseeritud ravimvormid
NO20004345L (no) Farmasøytisk sammensetning
DE69606663D1 (de) Förderer
DE69600083D1 (de) Förderer
DK0850426T3 (da) Transpondearrangement
FI951018A0 (fi) Hoeghastighetsdataoeverfoering i mobiltelesystem
DK0748583T3 (da) Mejetærsker
DK0825860T3 (da) Præpart
LV11727A (lv) Farmaceitiska kompozicija
FI973280A (fi) Farmaseuttinen koostumus
DK0818964T3 (da) Doseringsstift
BR9606756A (pt) Peptídeo
NO981052D0 (no) Peptidderivater
BR9610193A (pt) 4-Tiocarbamoil-1-(2-Pirazolil)-pirazóis
NO981051D0 (no) Peptidderivater
BR9605777A (pt) Composição farmacêutica
BR9605131A (pt) Composição farmacêutica
KR970007987U (ko) 유아용 식탁의자
SE9504467D0 (sv) Peptide
BR1100812A (pt) Peptìdeo
DE69601745D1 (de) Förderer
FI1900U1 (fi) Spejningsbraeda foer katter i hoeghus
FI1803U1 (fi) Anordning i saollskopa
FI1872U1 (fi) I dryckesbackar anvaendbart reklammaterial
FI2050U1 (fi) Rullstol foer fastmontering i fordonsgolv

Legal Events

Date Code Title Description
HC1A Change of owner name
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20141030