EE04216B1 - Vedel polümeerne kompositsioon ning selle kasutamine ravimina, mis on ette nähtud hüdrofoobse bioaktiivse aine reguleeritud vabastamiseks loomorganismis - Google Patents

Vedel polümeerne kompositsioon ning selle kasutamine ravimina, mis on ette nähtud hüdrofoobse bioaktiivse aine reguleeritud vabastamiseks loomorganismis

Info

Publication number
EE04216B1
EE04216B1 EEP200000539A EEP200000539A EE04216B1 EE 04216 B1 EE04216 B1 EE 04216B1 EE P200000539 A EEP200000539 A EE P200000539A EE P200000539 A EEP200000539 A EE P200000539A EE 04216 B1 EE04216 B1 EE 04216B1
Authority
EE
Estonia
Prior art keywords
controlled release
polymeric composition
medicament
animal
liquid polymeric
Prior art date
Application number
EEP200000539A
Other languages
English (en)
Estonian (et)
Inventor
T. Chern Rey
R. Zingerman Joel
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9815801.7A external-priority patent/GB9815801D0/en
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of EE200000539A publication Critical patent/EE200000539A/xx
Publication of EE04216B1 publication Critical patent/EE04216B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
EEP200000539A 1998-03-19 1999-03-18 Vedel polümeerne kompositsioon ning selle kasutamine ravimina, mis on ette nähtud hüdrofoobse bioaktiivse aine reguleeritud vabastamiseks loomorganismis EE04216B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7957498P 1998-03-19 1998-03-19
GBGB9815801.7A GB9815801D0 (en) 1998-07-21 1998-07-21 Liquid polymeric compositions for controlled released bioactive substances
PCT/US1999/005938 WO1999047073A1 (en) 1998-03-19 1999-03-18 Liquid polymeric compositions for controlled release of bioactive substances

Publications (2)

Publication Number Publication Date
EE200000539A EE200000539A (et) 2002-02-15
EE04216B1 true EE04216B1 (et) 2004-02-16

Family

ID=26314072

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000539A EE04216B1 (et) 1998-03-19 1999-03-18 Vedel polümeerne kompositsioon ning selle kasutamine ravimina, mis on ette nähtud hüdrofoobse bioaktiivse aine reguleeritud vabastamiseks loomorganismis

Country Status (30)

Country Link
EP (2) EP1484033B1 (id)
KR (1) KR100684055B1 (id)
CN (1) CN1263435C (id)
AT (1) ATE269676T1 (id)
AU (1) AU745841B2 (id)
BG (1) BG64782B1 (id)
BR (1) BRPI9908893B8 (id)
CA (1) CA2324265C (id)
CY (1) CY1111669T1 (id)
CZ (1) CZ300822B6 (id)
DE (1) DE69918275T2 (id)
DK (1) DK1063942T3 (id)
EA (1) EA003460B1 (id)
EE (1) EE04216B1 (id)
ES (1) ES2222694T3 (id)
HK (2) HK1031990A1 (id)
HR (1) HRP20000618B1 (id)
HU (1) HU226711B1 (id)
ID (1) ID25808A (id)
IL (2) IL137982A0 (id)
IS (1) IS2221B (id)
ME (1) ME00867B (id)
NO (1) NO329589B1 (id)
NZ (1) NZ506415A (id)
PL (1) PL192270B1 (id)
PT (1) PT1063942E (id)
SI (1) SI1063942T1 (id)
SK (1) SK286612B6 (id)
TR (1) TR200002685T2 (id)
WO (1) WO1999047073A1 (id)

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EP1299048A4 (en) * 2000-06-28 2005-09-28 Atul J Shukla BIODEGRADABLE VEHICLES AND SYSTEMS FOR DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES
CN102871979B (zh) * 2000-09-01 2014-10-22 帕尔马亚有限公司 缓释药物制剂及其施用方法
EP1372729B1 (en) * 2001-02-23 2009-04-08 Genentech, Inc. Erodible polymers for injection
CA2466642C (en) * 2001-11-14 2011-01-18 Guohua Chen Injectable depot composition
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
WO2004103342A2 (en) * 2003-05-16 2004-12-02 Alkermes Controlled Therapeutics, Inc. Injectable sustained release compositions
CN1293921C (zh) * 2003-08-18 2007-01-10 王玉万 含乙基纤维素和脂肪酸酯类的长效注射剂
US9238127B2 (en) 2004-02-25 2016-01-19 Femasys Inc. Methods and devices for delivering to conduit
US8048101B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
US8052669B2 (en) 2004-02-25 2011-11-08 Femasys Inc. Methods and devices for delivery of compositions to conduits
US8048086B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
AR052155A1 (es) * 2004-12-14 2007-03-07 Novartis Ag Compuestos organicos
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
NZ552040A (en) * 2006-12-13 2009-04-30 Bomac Research Ltd Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
TW200924647A (en) * 2007-08-30 2009-06-16 Schering Plough Ltd Local topical administration formulations containing fipronil
BRPI0705822A2 (pt) * 2007-10-25 2009-06-23 Schering Plough Saude Animal Ltda formulação injetável com ação prolongada e uso de um agente semi-sintético derivado do grupo das avermectinas, em combinação com um polìmero biodegradável
US20090181068A1 (en) * 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
US20090281150A1 (en) * 2008-04-09 2009-11-12 Nicola Frances Bateman Compound 249
BRPI0802255A2 (pt) * 2008-06-17 2010-03-16 Sespo Ind E Com Ltda composição de uso tópico para controle de ectoparasitos em cães e gatos
US9554826B2 (en) 2008-10-03 2017-01-31 Femasys, Inc. Contrast agent injection system for sonographic imaging
US10070888B2 (en) 2008-10-03 2018-09-11 Femasys, Inc. Methods and devices for sonographic imaging
WO2010106325A2 (en) 2009-03-18 2010-09-23 Omnipharm Limited Parasiticidal formulation
DE102011114986A1 (de) * 2011-09-28 2013-03-28 Ethris Gmbh Sprühsystem
JP6564369B2 (ja) 2013-12-09 2019-08-21 デュレクト コーポレイション 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法
US8785426B1 (en) 2013-12-13 2014-07-22 Upsher-Smith Laboratories, Inc. Testosterone gel compositions and related methods
CN107811967B (zh) * 2016-09-09 2021-08-24 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) 抗寄生虫药物原位固化缓释注射剂及其制备方法
WO2019050259A1 (ko) * 2017-09-06 2019-03-14 (주)인벤티지랩 목시덱틴을 포함하는 마이크로 입자 및 이의 제조 방법
KR102101969B1 (ko) 2017-09-06 2020-04-22 (주)인벤티지랩 목시덱틴을 포함하는 마이크로 입자 및 이의 제조 방법
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
CN111675778B (zh) * 2020-06-15 2021-11-02 苏州大学 基于pisa方法制备的偶氮还原酶响应性的近红外聚合物荧光探针及其应用
EP4000688A1 (en) 2020-11-19 2022-05-25 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of trenbolone acetate having a definite particle size distribution
ES2948624T3 (es) 2020-11-19 2023-09-14 Fis Fabbrica Italiana Sintetici Spa Proceso mejorado para la preparación de trembolona y/o acetato de trembolona
EP4001288A1 (en) 2020-11-19 2022-05-25 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of trenbolone acetate having a definite particle size distribution and a irregular hexagon plates crystal habit

Family Cites Families (11)

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US4150108A (en) * 1975-12-29 1979-04-17 Graham Neil B Injectable medicinal compositions
US4489055A (en) * 1978-07-19 1984-12-18 N.V. Sopar S.A. Process for preparing biodegradable submicroscopic particles containing a biologically active substance and their use
EP0007895B1 (fr) * 1978-07-19 1983-06-22 Patrick Couvreur Nanoparticules biodégradables, compositions pharmaceutiques les contenant et procédé pour leur préparation
US4333919A (en) * 1979-09-12 1982-06-08 Eli Lilly And Company Growth promotant controlled release formulations and method of treatment
US4331652A (en) * 1979-09-12 1982-05-25 Eli Lilly And Company Controlled release parasitic formulations and method
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
DE3378250D1 (en) * 1982-04-22 1988-11-24 Ici Plc Continuous release formulations
DE3400106A1 (de) * 1984-01-04 1985-07-11 Klaus-Dieter Dr. 3550 Marburg Bremecker Pharmazeutische zubereitungen mit gesteuerter arzneistoff-freisetzung
IT1250654B (it) * 1991-07-08 1995-04-21 Farcon Ag Metodo per la preparazione di forme farmaceutiche orali a rilascio prolungato contenenti sostanze attive a solubilita' dipendente dal valore di ph.
AU2605592A (en) * 1991-10-15 1993-04-22 Atrix Laboratories, Inc. Polymeric compositions useful as controlled release implants
ATE173616T1 (de) * 1992-11-30 1998-12-15 Pfizer Verabreichungsvorrichtungen mit gestützten flüssigen membranen

Also Published As

Publication number Publication date
CA2324265A1 (en) 1999-09-23
EP1484033A1 (en) 2004-12-08
ME00867B (me) 2008-08-07
ID25808A (id) 2000-11-09
CY1111669T1 (el) 2015-10-07
CN1293553A (zh) 2001-05-02
BG104838A (en) 2001-07-31
IS2221B (is) 2007-03-15
CN1263435C (zh) 2006-07-12
NZ506415A (en) 2003-06-30
HK1036579A1 (en) 2002-01-11
AU745841B2 (en) 2002-04-11
NO20004616D0 (no) 2000-09-15
BR9908893B1 (pt) 2013-11-19
DE69918275T2 (de) 2005-07-07
EP1484033B1 (en) 2011-02-23
HRP20000618B1 (en) 2010-10-31
AU3010099A (en) 1999-10-11
EP1063942A4 (en) 2002-07-10
HUP0102385A3 (en) 2002-12-28
PT1063942E (pt) 2004-10-29
DE69918275D1 (de) 2004-07-29
HK1031990A1 (en) 2001-07-06
SI1063942T1 (en) 2004-10-31
IL137982A0 (en) 2001-10-31
EA003460B1 (ru) 2003-06-26
BR9908893A (pt) 2000-11-28
HRP20000618A2 (en) 2001-08-31
KR100684055B1 (ko) 2007-02-16
CA2324265C (en) 2008-08-05
KR20010041987A (ko) 2001-05-25
SK286612B6 (sk) 2009-02-05
EE200000539A (et) 2002-02-15
NO20004616L (no) 2000-09-15
BG64782B1 (bg) 2006-04-28
EA200000964A1 (ru) 2001-02-26
HUP0102385A2 (hu) 2002-03-28
HU226711B1 (en) 2009-07-28
PL192270B1 (pl) 2006-09-29
WO1999047073A1 (en) 1999-09-23
DK1063942T3 (da) 2005-11-07
TR200002685T2 (tr) 2000-12-21
ES2222694T3 (es) 2005-02-01
CZ20003420A3 (en) 2001-05-16
SK13752000A3 (sk) 2001-03-12
ATE269676T1 (de) 2004-07-15
NO329589B1 (no) 2010-11-15
EP1063942B1 (en) 2004-06-23
EP1063942A1 (en) 2001-01-03
PL342858A1 (en) 2001-07-16
IS5599A (is) 2000-08-22
IL137982A (en) 2006-10-05
CZ300822B6 (cs) 2009-08-19
BRPI9908893B8 (pt) 2021-05-25

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Legal Events

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Effective date: 20041231

KB4A Valid patent at the end of a year

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KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

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Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231

HC1A Change of owner name