EE03764B1 - Difenüülalküültetrahüdropüridiinid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon - Google Patents
Difenüülalküültetrahüdropüridiinid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioonInfo
- Publication number
- EE03764B1 EE03764B1 EEP199900238A EE9900238A EE03764B1 EE 03764 B1 EE03764 B1 EE 03764B1 EE P199900238 A EEP199900238 A EE P199900238A EE 9900238 A EE9900238 A EE 9900238A EE 03764 B1 EE03764 B1 EE 03764B1
- Authority
- EE
- Estonia
- Prior art keywords
- pct
- preparation
- diphenylalkyltetrahydropyridines
- pharmaceutical composition
- composition containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9615336A FR2757161B1 (fr) | 1996-12-13 | 1996-12-13 | Diphenylalkyl-tetrahydropyridines |
| PCT/FR1997/002289 WO1998025904A1 (fr) | 1996-12-13 | 1997-12-12 | Diphenylalkyl-tetrahydropyridines, procede pour leur preparation et composition pharmaceutique les contenant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE9900238A EE9900238A (et) | 1999-12-15 |
| EE03764B1 true EE03764B1 (et) | 2002-06-17 |
Family
ID=9498642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP199900238A EE03764B1 (et) | 1996-12-13 | 1997-12-12 | Difenüülalküültetrahüdropüridiinid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6124318A (de) |
| EP (1) | EP0950049B1 (de) |
| JP (1) | JP2001505903A (de) |
| KR (1) | KR100549656B1 (de) |
| CN (1) | CN1144784C (de) |
| AT (1) | ATE207056T1 (de) |
| AU (1) | AU730142B2 (de) |
| BR (1) | BR9713926A (de) |
| CA (1) | CA2274946C (de) |
| CY (1) | CY2282B1 (de) |
| CZ (1) | CZ290242B6 (de) |
| DE (1) | DE69707504T2 (de) |
| DK (1) | DK0950049T3 (de) |
| EE (1) | EE03764B1 (de) |
| ES (1) | ES2167805T3 (de) |
| FR (1) | FR2757161B1 (de) |
| HK (1) | HK1024001A1 (de) |
| HU (1) | HUP0001437A3 (de) |
| IL (2) | IL130001A0 (de) |
| IS (1) | IS2001B (de) |
| NO (1) | NO313282B1 (de) |
| NZ (1) | NZ336032A (de) |
| PL (1) | PL192926B1 (de) |
| PT (1) | PT950049E (de) |
| RS (1) | RS49672B (de) |
| RU (1) | RU2198874C2 (de) |
| SI (1) | SI0950049T1 (de) |
| SK (1) | SK283332B6 (de) |
| TR (1) | TR199901290T2 (de) |
| UA (1) | UA52708C2 (de) |
| WO (1) | WO1998025904A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2763847B1 (fr) * | 1997-05-28 | 2003-06-06 | Sanofi Sa | Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1 |
| WO2001078709A2 (en) * | 2000-04-12 | 2001-10-25 | Minerva Biotechnologies Corporation | Treatment of neurodegenerative disease |
| US6699866B2 (en) | 2001-04-17 | 2004-03-02 | Sepracor Inc. | Thiazole and other heterocyclic ligands for mammalian dopamine, muscarinic and serotonin receptors and transporters, and methods of use thereof |
| CA2551946A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Immediate, controlled and sustained release formulations of galantamine |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1321701A (en) * | 1969-10-01 | 1973-06-27 | Continental Pharma | Amino-alcohols their salts and process for prepairing the same |
| BE775611A (fr) * | 1970-11-24 | 1972-03-16 | Synthelabo | Derives de la (diphenyl-3,3 propyl-1)-1 piperidine, leur preparation etles medicaments qui en contiennent |
| FR2650505B1 (fr) * | 1989-08-07 | 1994-06-03 | Midy Spa | Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale |
| US5266573A (en) * | 1989-08-07 | 1993-11-30 | Elf Sanofi | Trifluoromethylphenyltetrahydropyridines for the treatment and/or prophylaxis of intestinal motility disorders |
| FR2662355B1 (fr) * | 1990-05-22 | 1994-11-10 | Sanofi Sa | Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux. |
| US5512584A (en) * | 1991-04-16 | 1996-04-30 | Basf Aktiengesellschaft | 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof |
| HU211019B (en) * | 1991-12-02 | 1995-09-28 | Richter Gedeon Vegyeszet | Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds |
| DK148392D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Heterocykliske forbindelser |
-
1996
- 1996-12-13 FR FR9615336A patent/FR2757161B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-11 US US09/331,005 patent/US6124318A/en not_active Expired - Fee Related
- 1997-12-12 KR KR1019997005202A patent/KR100549656B1/ko not_active IP Right Cessation
- 1997-12-12 NZ NZ336032A patent/NZ336032A/xx unknown
- 1997-12-12 CN CNB971805830A patent/CN1144784C/zh not_active Expired - Fee Related
- 1997-12-12 RU RU99115082/04A patent/RU2198874C2/ru not_active IP Right Cessation
- 1997-12-12 ES ES97951326T patent/ES2167805T3/es not_active Expired - Lifetime
- 1997-12-12 PL PL334073A patent/PL192926B1/pl not_active IP Right Cessation
- 1997-12-12 UA UA99063287A patent/UA52708C2/uk unknown
- 1997-12-12 RS YUP-263/99A patent/RS49672B/sr unknown
- 1997-12-12 CZ CZ19992110A patent/CZ290242B6/cs not_active IP Right Cessation
- 1997-12-12 CA CA002274946A patent/CA2274946C/en not_active Expired - Fee Related
- 1997-12-12 DE DE69707504T patent/DE69707504T2/de not_active Expired - Fee Related
- 1997-12-12 SK SK787-99A patent/SK283332B6/sk unknown
- 1997-12-12 DK DK97951326T patent/DK0950049T3/da active
- 1997-12-12 HU HU0001437A patent/HUP0001437A3/hu unknown
- 1997-12-12 AU AU54895/98A patent/AU730142B2/en not_active Ceased
- 1997-12-12 PT PT97951326T patent/PT950049E/pt unknown
- 1997-12-12 WO PCT/FR1997/002289 patent/WO1998025904A1/fr not_active Application Discontinuation
- 1997-12-12 AT AT97951326T patent/ATE207056T1/de not_active IP Right Cessation
- 1997-12-12 TR TR1999/01290T patent/TR199901290T2/xx unknown
- 1997-12-12 JP JP52632398A patent/JP2001505903A/ja not_active Ceased
- 1997-12-12 EE EEP199900238A patent/EE03764B1/xx not_active IP Right Cessation
- 1997-12-12 BR BR9713926A patent/BR9713926A/pt not_active Application Discontinuation
- 1997-12-12 EP EP97951326A patent/EP0950049B1/de not_active Expired - Lifetime
- 1997-12-12 SI SI9730241T patent/SI0950049T1/xx unknown
- 1997-12-12 IL IL13000197A patent/IL130001A0/xx active IP Right Grant
-
1999
- 1999-05-18 IL IL130001A patent/IL130001A/en not_active IP Right Cessation
- 1999-06-10 IS IS5074A patent/IS2001B/is unknown
- 1999-06-11 NO NO19992870A patent/NO313282B1/no unknown
-
2000
- 2000-05-31 HK HK00103246A patent/HK1024001A1/xx not_active IP Right Cessation
-
2002
- 2002-05-15 CY CY0200036A patent/CY2282B1/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20021231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20031231 |
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| HC1A | Change of owner name | ||
| KB4A | Valid patent at the end of a year |
Effective date: 20041231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20051231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20061231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20071231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20081231 |
|
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20081212 |