EE03764B1 - Difenüülalküültetrahüdropüridiinid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon - Google Patents

Difenüülalküültetrahüdropüridiinid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon

Info

Publication number
EE03764B1
EE03764B1 EEP199900238A EE9900238A EE03764B1 EE 03764 B1 EE03764 B1 EE 03764B1 EE P199900238 A EEP199900238 A EE P199900238A EE 9900238 A EE9900238 A EE 9900238A EE 03764 B1 EE03764 B1 EE 03764B1
Authority
EE
Estonia
Prior art keywords
pct
preparation
diphenylalkyltetrahydropyridines
pharmaceutical composition
composition containing
Prior art date
Application number
EEP199900238A
Other languages
English (en)
Estonian (et)
Other versions
EE9900238A (et
Inventor
Baroni Marco
Cardamone Rosanna
Fournier Jacqueline
Guzzi Umberto
Original Assignee
Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi filed Critical Sanofi
Publication of EE9900238A publication Critical patent/EE9900238A/xx
Publication of EE03764B1 publication Critical patent/EE03764B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP199900238A 1996-12-13 1997-12-12 Difenüülalküültetrahüdropüridiinid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon EE03764B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9615336A FR2757161B1 (fr) 1996-12-13 1996-12-13 Diphenylalkyl-tetrahydropyridines
PCT/FR1997/002289 WO1998025904A1 (fr) 1996-12-13 1997-12-12 Diphenylalkyl-tetrahydropyridines, procede pour leur preparation et composition pharmaceutique les contenant

Publications (2)

Publication Number Publication Date
EE9900238A EE9900238A (et) 1999-12-15
EE03764B1 true EE03764B1 (et) 2002-06-17

Family

ID=9498642

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900238A EE03764B1 (et) 1996-12-13 1997-12-12 Difenüülalküültetrahüdropüridiinid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon

Country Status (31)

Country Link
US (1) US6124318A (xx)
EP (1) EP0950049B1 (xx)
JP (1) JP2001505903A (xx)
KR (1) KR100549656B1 (xx)
CN (1) CN1144784C (xx)
AT (1) ATE207056T1 (xx)
AU (1) AU730142B2 (xx)
BR (1) BR9713926A (xx)
CA (1) CA2274946C (xx)
CY (1) CY2282B1 (xx)
CZ (1) CZ290242B6 (xx)
DE (1) DE69707504T2 (xx)
DK (1) DK0950049T3 (xx)
EE (1) EE03764B1 (xx)
ES (1) ES2167805T3 (xx)
FR (1) FR2757161B1 (xx)
HK (1) HK1024001A1 (xx)
HU (1) HUP0001437A3 (xx)
IL (2) IL130001A0 (xx)
IS (1) IS2001B (xx)
NO (1) NO313282B1 (xx)
NZ (1) NZ336032A (xx)
PL (1) PL192926B1 (xx)
PT (1) PT950049E (xx)
RS (1) RS49672B (xx)
RU (1) RU2198874C2 (xx)
SI (1) SI0950049T1 (xx)
SK (1) SK283332B6 (xx)
TR (1) TR199901290T2 (xx)
UA (1) UA52708C2 (xx)
WO (1) WO1998025904A1 (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763847B1 (fr) * 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
WO2001078709A2 (en) * 2000-04-12 2001-10-25 Minerva Biotechnologies Corporation Treatment of neurodegenerative disease
US6699866B2 (en) 2001-04-17 2004-03-02 Sepracor Inc. Thiazole and other heterocyclic ligands for mammalian dopamine, muscarinic and serotonin receptors and transporters, and methods of use thereof
CA2551946A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Immediate, controlled and sustained release formulations of galantamine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1321701A (en) * 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
BE775611A (fr) * 1970-11-24 1972-03-16 Synthelabo Derives de la (diphenyl-3,3 propyl-1)-1 piperidine, leur preparation etles medicaments qui en contiennent
FR2650505B1 (fr) * 1989-08-07 1994-06-03 Midy Spa Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
US5266573A (en) * 1989-08-07 1993-11-30 Elf Sanofi Trifluoromethylphenyltetrahydropyridines for the treatment and/or prophylaxis of intestinal motility disorders
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
US5512584A (en) * 1991-04-16 1996-04-30 Basf Aktiengesellschaft 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof
HU211019B (en) * 1991-12-02 1995-09-28 Richter Gedeon Vegyeszet Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser

Also Published As

Publication number Publication date
BR9713926A (pt) 2000-03-21
DE69707504T2 (de) 2002-06-27
CN1144784C (zh) 2004-04-07
KR20000069421A (ko) 2000-11-25
CZ211099A3 (cs) 1999-09-15
WO1998025904A1 (fr) 1998-06-18
SK78799A3 (en) 1999-12-10
SI0950049T1 (en) 2002-10-31
EP0950049B1 (fr) 2001-10-17
HUP0001437A3 (en) 2001-12-28
ES2167805T3 (es) 2002-05-16
NO992870L (no) 1999-08-11
FR2757161A1 (fr) 1998-06-19
NO992870D0 (no) 1999-06-11
IS2001B (is) 2005-04-15
EP0950049A1 (fr) 1999-10-20
KR100549656B1 (ko) 2006-02-08
DK0950049T3 (da) 2002-01-28
FR2757161B1 (fr) 1999-03-12
SK283332B6 (sk) 2003-06-03
NZ336032A (en) 2000-12-22
CA2274946A1 (en) 1998-06-18
PT950049E (pt) 2002-03-28
IS5074A (is) 1999-06-10
RS49672B (sr) 2007-11-15
TR199901290T2 (xx) 1999-08-23
DE69707504D1 (de) 2001-11-22
YU26399A (sh) 2000-03-21
NO313282B1 (no) 2002-09-09
CY2282B1 (en) 2003-07-04
EE9900238A (et) 1999-12-15
PL192926B1 (pl) 2006-12-29
CA2274946C (en) 2005-09-20
AU730142B2 (en) 2001-03-01
HK1024001A1 (en) 2000-09-29
PL334073A1 (en) 2000-01-31
UA52708C2 (uk) 2003-01-15
US6124318A (en) 2000-09-26
JP2001505903A (ja) 2001-05-08
IL130001A (en) 2006-04-10
CZ290242B6 (cs) 2002-06-12
HUP0001437A2 (hu) 2000-09-28
IL130001A0 (en) 2000-02-29
AU5489598A (en) 1998-07-03
ATE207056T1 (de) 2001-11-15
CN1240428A (zh) 2000-01-05
RU2198874C2 (ru) 2003-02-20

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

HC1A Change of owner name
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20081212